دورية أكاديمية
Cardiac dysfunction in survivors of sepsis: a scoping review.
| العنوان: | Cardiac dysfunction in survivors of sepsis: a scoping review. |
|---|---|
| المؤلفون: | Garrity, Kevin, Gaw, Samantha, Blewitt, Alice, Canon, Paul, McCall, Philip, McPeake, Joanne |
| بيانات النشر: | BMJ Publishing Group Department of Public Health and Primary Care Open Heart |
| سنة النشر: | 2023 |
| المجموعة: | Apollo - University of Cambridge Repository |
| مصطلحات موضوعية: | biomarkers, cardiac imaging techniques, heart failure, outcome assessment, health care, risk factors, Adult, Humans, Myocardial Infarction, Arrhythmias, Cardiac, Hospitalization, Sepsis, Survivors |
| الوصف: | BACKGROUND: Sepsis is associated with an increased risk of adverse cardiovascular events in a magnitude comparable to other major cardiovascular risk factors. Sepsis is one of the most common reasons for intensive care admission and survivors often have significant functional limitations following discharge. However, it is not clear to what extent chronic cardiovascular dysfunction might mediate these functional impairments, or how we might screen and manage these patients at risk of chronic cardiovascular disease. We conducted a scoping review to map existing evidence and identify research gaps relating to cardiovascular dysfunction following sepsis. METHODS: We conducted a systematic search of MEDLINE, Embase and CINAHL databases using a concept, context, population (CoCoPop) framework. Studies examining cardiovascular outcomes or symptoms following an episode of sepsis in adults were included. Data were mapped based on the population assessed, cardiovascular outcomes examined, inclusion of objective measures of cardiac dysfunction such as biomarkers or cardiovascular imaging, or whether cardiovascular symptoms or patient-reported functional outcomes measures were recorded. RESULTS: We identified 11 210 articles of which 70 were eligible for full text review and 28 were included in final analysis. Across our dataset, a wide range of incident cardiovascular outcomes were reported in the literature including incidence of congestive heart failure (13/28), arrhythmia (6/28), myocardial infarction (24/28) or cardiovascular death or all-cause mortality (20/28). Only 39% (11/28) of articles reported objective measures of cardiovascular function and only one article related cardiovascular function to functional impairment via patient-reported outcome measures. CONCLUSION: There are significant gaps in our understanding of cardiac dysfunction following sepsis . While the research highlights the strong association of sepsis with a variety of adverse cardiovascular outcomes, further prospective work is required to ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://www.repository.cam.ac.uk/handle/1810/360835Test; https://doi.org/10.17863/CAM.104067Test |
| DOI: | 10.17863/CAM.104067 |
| الإتاحة: | https://doi.org/10.17863/CAM.104067Test https://www.repository.cam.ac.uk/handle/1810/360835Test |
| حقوق: | Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.12DBA3D |
| قاعدة البيانات: | BASE |
| DOI: | 10.17863/CAM.104067 |
|---|