المؤلفون: Cai, Huiqiang, Zhang, Bin, Ahrenfeldt, Johanne, Joseph, Justin V., Riedel, Maria, Gao, Zongliang, Thomsen, Sofie K., Christensen, Ditte S., Bak, Rasmus O., Hager, Henrik, Vendelbo, Mikkel H., Gao, Xin, Birkbak, Nicolai, Thomsen, Martin K.

المصدر: Cai , H , Zhang , B , Ahrenfeldt , J , Joseph , J V , Riedel , M , Gao , Z , Thomsen , S K , Christensen , D S , Bak , R O , Hager , H , Vendelbo , M H , Gao , X , Birkbak , N & Thomsen , M K 2024 , ' CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression ' , Nature Communications , vol. 15 , no. 1 , 2088 . https://doi.org/10.1038/s41467-024-46370-0Test , https://doi.org/10.1038/s41467-024-46370-0Test

مصطلحات موضوعية: Male, Humans, Animals, Mice, CRISPR-Cas Systems/genetics, Prostatic Neoplasms/genetics, Transcriptome, Multigene Family

العلاقة: https://pure.au.dk/portal/en/publications/48136e79-1998-4e13-986b-0c921f9b3f18Test

الإتاحة: https://doi.org/10.1038/s41467-024-46370-0Test
https://pure.au.dk/portal/en/publications/48136e79-1998-4e13-986b-0c921f9b3f18Test
http://www.scopus.com/inward/record.url?scp=85187165808&partnerID=8YFLogxKTest

المؤلفون: Ren, Fanghui, Narita, Ryo, Rashidi, Ahmad S., Fruhwürth, Stefanie, Gao, Zongliang, Bak, Rasmus O., Thomsen, Martin K., Verjans, Georges M.G.M., Reinert, Line S., Paludan, Søren R.

المصدر: Ren , F , Narita , R , Rashidi , A S , Fruhwürth , S , Gao , Z , Bak , R O , Thomsen , M K , Verjans , G M G M , Reinert , L S & Paludan , S R 2023 , ' ER stress induces caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with herpes simplex virus type 2 ' , EMBO Journal , vol. 42 , no. 19 , e113118 . https://doi.org/10.15252/embj.2022113118Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://pure.eur.nl/en/publications/9b1dd6ca-de2b-458e-88e7-20b93ca5858fTest

الإتاحة: https://doi.org/10.15252/embj.2022113118Test
https://pure.eur.nl/en/publications/9b1dd6ca-de2b-458e-88e7-20b93ca5858fTest
https://pure.eur.nl/ws/files/99254189/ER_stress_induces_caspase-2-tBID-GSDME-dependent_cell_death_in_neurons_lytically_infected_with_herpes_simplex_virus_type_2.pdfTest
http://www.scopus.com/inward/record.url?scp=85168994590&partnerID=8YFLogxKTest

المؤلفون: Neldeborg, Signe, Soerensen, Johannes Frasez, Møller, Charlotte Thornild, Bill, Marie, Gao, Zongliang, Bak, Rasmus O, Holm, Kasper, Sorensen, Boe, Nyegaard, Mette, Luo, Yonglun, Hokland, Peter, Stougaard, Magnus, Ludvigsen, Maja, Holm, Christian Kanstrup

المصدر: Neldeborg , S , Soerensen , J F , Møller , C T , Bill , M , Gao , Z , Bak , R O , Holm , K , Sorensen , B , Nyegaard , M , Luo , Y , Hokland , P , Stougaard , M , Ludvigsen , M & Holm , C K 2023 , ' Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo ' , Leukemia , vol. 37 , no. 9 , pp. 1792-1801 . https://doi.org/10.1038/s41375-023-01950-9Test

مصطلحات موضوعية: Animals, Mice, RUNX1 Translocation Partner 1 Protein/genetics, Translocation, Genetic, Introns/genetics, Core Binding Factor Alpha 2 Subunit/genetics, Tumor Burden, CRISPR-Cas Systems, Leukemia, Myeloid, Acute/genetics, Cell Proliferation, Oncogene Proteins, Fusion/genetics

العلاقة: https://pure.au.dk/portal/en/publications/3bc00f3a-ee60-4a4f-a33f-1767984373aaTest

الإتاحة: https://doi.org/10.1038/s41375-023-01950-9Test
https://pure.au.dk/portal/en/publications/3bc00f3a-ee60-4a4f-a33f-1767984373aaTest

المؤلفون: Gao, Zongliang, Ravendran, Sujan, Mikkelsen, Nanna S., Haldrup, Jakob, Cai, Huiqiang, Ding, Xiangning, Paludan, Søren R., Thomsen, Martin K., Mikkelsen, Jacob Giehm, Bak, Rasmus O.

المصدر: Gao , Z , Ravendran , S , Mikkelsen , N S , Haldrup , J , Cai , H , Ding , X , Paludan , S R , Thomsen , M K , Mikkelsen , J G & Bak , R O 2022 , ' A truncated reverse transcriptase enhances prime editing by split AAV vectors ' , Molecular Therapy , vol. 30 , no. 9 , pp. 2942-2951 . https://doi.org/10.1016/j.ymthe.2022.07.001Test

مصطلحات موضوعية: AAV vectors, CRISPR-Cas9, gene editing, gene therapy, in vivo delivery, PASTE, prime editing, reverse transcriptase, Dependovirus/genetics, Animals, CRISPR-Cas Systems, Genetic Vectors/genetics, Proprotein Convertase 9/genetics, Mice, RNA, Guide, Kinetoplastida/genetics, RNA-Directed DNA Polymerase/genetics

العلاقة: https://pure.au.dk/portal/en/publications/f8e75b2d-a57b-496a-b465-f74b4080a2dcTest

الإتاحة: https://doi.org/10.1016/j.ymthe.2022.07.001Test
https://pure.au.dk/portal/en/publications/f8e75b2d-a57b-496a-b465-f74b4080a2dcTest
http://www.scopus.com/inward/record.url?scp=85134827831&partnerID=8YFLogxKTest
https://www.biorxiv.org/content/biorxiv/early/2021/11/05/2021.11.05.467423.full.pdfTest

المؤلفون: Jensen, Trine I, Mikkelsen, Nanna S, Gao, Zongliang, Foßelteder, Johannes, Pabst, Gabriel, Axelgaard, Esben, Laustsen, Anders, König, Saskia, Reinisch, Andreas, Bak, Rasmus O

المصدر: Jensen , T I , Mikkelsen , N S , Gao , Z , Foßelteder , J , Pabst , G , Axelgaard , E , Laustsen , A , König , S , Reinisch , A & Bak , R O 2021 , ' Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi ' , Genome Research , vol. 31 , no. 11 , pp. 2120-2130 . https://doi.org/10.1101/gr.275607.121Test

مصطلحات موضوعية: ACTIVATION, HIGHLY EFFICIENT

وصف الملف: application/pdf

العلاقة: https://pure.au.dk/portal/en/publications/d10b3bb3-78d9-4324-be7a-a6fbc615798bTest

الإتاحة: https://doi.org/10.1101/gr.275607.121Test
https://pure.au.dk/portal/en/publications/d10b3bb3-78d9-4324-be7a-a6fbc615798bTest
https://pure.au.dk/ws/files/273859097/Genome_Res._2021_Jensen_2120_30.pdfTest

المؤلفون: Gao, Zongliang, Van Der Velden, Yme Ubeles, Fan, Minghui, Van Der Linden, Cynthia Alyssa, Vink, Monique, Herrera-Carrillo, Elena, Berkhout, Ben

المصدر: Gao , Z , Van Der Velden , Y U , Fan , M , Van Der Linden , C A , Vink , M , Herrera-Carrillo , E & Berkhout , B 2021 , ' Engineered miniature H1 promoters with dedicated RNA polymerase II or III activity ' , Journal of Biological Chemistry , vol. 296 , 100026 . https://doi.org/10.1074/jbc.RA120.015386Test

الإتاحة: https://doi.org/10.1074/jbc.RA120.015386Test
https://pure.au.dk/portal/da/publications/engineered-miniature-h1-promoters-with-dedicated-rna-polymerase-ii-or-iii-activityTest(a1fe5f4a-baf4-4d1e-bf54-6f806d524b0b).html
http://www.scopus.com/inward/record.url?scp=85102940590&partnerID=8YFLogxKTest

المؤلفون: Gao, Zongliang, Fan, Minghui, Das, Atze T, Herrera-Carrillo, Elena, Berkhout, Ben

المساهمون: Chinese Government Scholarship, NIH, Aids Fonds, King Baudouin Foundation

المصدر: Nucleic Acids Research ; volume 48, issue 10, page 5527-5539 ; ISSN 0305-1048 1362-4962

مصطلحات موضوعية: Genetics

الإتاحة: https://doi.org/10.1093/nar/gkaa226Test
http://academic.oup.com/nar/article-pdf/48/10/5527/33326136/gkaa226.pdfTest

المؤلفون: You, Chen, Li, Zhen, Li, Meng, Gao, Zongliang, Li, Wei

المصدر: Journal of Physics: Conference Series ; volume 1631, issue 1, page 012054 ; ISSN 1742-6588 1742-6596

الإتاحة: https://doi.org/10.1088/1742-6596/1631/1/012054Test

المؤلفون: Wedge, Eileen, Ahmadov, Ulvi, Hansen, Thomas B, Gao, Zongliang, Tulstrup, Morten, Côme, Christophe, Nonavinkere Srivatsan, Sridhar, Ahmed, Tanzir, Jespersen, Jakob S, Schlotmann, Balthasar C, Schöllkopf, Claudia, Raaschou-Jensen, Klas, Ødum, Niels, Kjems, Jørgen, Bak, Rasmus O, Walter, Matthew J, Grønbæk, Kirsten, Kristensen, Lasse S

المصدر: Wedge , E , Ahmadov , U , Hansen , T B , Gao , Z , Tulstrup , M , Côme , C , Nonavinkere Srivatsan , S , Ahmed , T , Jespersen , J S , Schlotmann , B C , Schöllkopf , C , Raaschou-Jensen , K , Ødum , N , Kjems , J , Bak , R O , Walter , M J , Grønbæk , K & Kristensen , L S 2023 , ' Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms ' , Leukemia , vol. 37 , ....

مصطلحات موضوعية: Animals, Doxycycline, Mice, Mutation, Myelodysplastic Syndromes/genetics, Neoplasms, RNA Splicing, RNA Splicing Factors/genetics, RNA, Circular/genetics, Splicing Factor U2AF/genetics

الإتاحة: https://doi.org/10.1038/s41375-023-01866-4Test
https://pure.au.dk/portal/da/publications/impact-of-u2af1-mutations-on-circular-rna-expression-in-myelodysplastic-neoplasmsTest(3de8bf0a-a973-4385-b2c9-1ac1bb734ed6).html
http://www.scopus.com/inward/record.url?scp=85149954219&partnerID=8YFLogxKTest

المؤلفون: Gao, Zongliang, Berkhout, Ben, Herrera-Carrillo, Elena

المساهمون: Chinese Government Scholarship, ZonMw

المصدر: RNA Biology ; volume 16, issue 7, page 890-898 ; ISSN 1547-6286 1555-8584

الإتاحة: https://doi.org/10.1080/15476286.2019.1599259Test