المؤلفون: Joshua Abd Alla, Ursula Quitterer

المصدر: Cells; Volume 11; Issue 4; Pages: 654

مصطلحات موضوعية: RKIP (RAF kinase inhibitor protein), PEBP1 (phosphatidylethanolamine-binding protein 1), RAF1, GRK2 (G protein-coupled receptor kinase 2), AGTR1 (angiotensin II receptor type 1), MAPK (mitogen-activated protein kinase), tumour suppressor, heart failure, fibrosis

وصف الملف: application/pdf

العلاقة: Cell Microenvironment; https://dx.doi.org/10.3390/cells11040654Test

الإتاحة: https://doi.org/10.3390/cells11040654Test

المؤلفون: Abd Alla, Joshua, Quitterer, Ursula

المصدر: Cells, 11 (4)

مصطلحات موضوعية: RKIP (RAF kinase inhibitor protein), PEBP1 (phosphatidylethanolamine-binding protein 1), RAF1, GRK2 (G protein-coupled receptor kinase 2), AGTR1 (angiotensin II receptor type 1), MAPK (mitogen-activated protein kinase), Tumour suppressor, Heart failure, Fibrosis

وصف الملف: application/application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/wos/000762049900001; info:eu-repo/grantAgreement/SNF/Projektförderung in Biologie und Medizin (Abteilung III)/140679; info:eu-repo/grantAgreement/SNF/Projekte Lebenswissenschaften/169354; http://hdl.handle.net/20.500.11850/533339Test

الإتاحة: https://doi.org/20.500.11850/533339Test
https://doi.org/10.3929/ethz-b-000533339Test
https://doi.org/10.3390/cells11040654Test
https://hdl.handle.net/20.500.11850/533339Test

المؤلفون: Seunghun P. Lee, Jenson Qi, Guozhang Xu, Matthew M. Rankin, James Littrell, June Zhi Xu, Ivona Bakaj, Alessandro Pocai

المصدر: Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: GRK2 = G protein–coupled receptor kinase 2, GLP-1, diabetes, obesity, NASH, insulin secretion, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2021.652628/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/c5c8decb80f8469c94f501e6c8a341aeTest

المؤلفون: Denise Veltman, Piet Claus, Ellen Caluwé, Maarten Vanhaverbeke, Uwe Himmelreich, Stefan Janssens, Peter Pokreisz, Peter Sinnaeve, Willy Gsell, Ming Wu, Hilde Gillijns

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: Pathology, PRR, pattern recognition receptor, TnT, troponin T, Angiogenesis, CAD, coronary artery disease, NS, not significant, DAMP, damage-associated molecular pattern, SMC, smooth muscle cell, MPO, myeloperoxidase, myocardial remodeling, Car3, carbonic anhydrase 3, Transcriptome, Myocyte, magnetic resonance imaging, CMC, cardiac myocyte, Cxcr2, CXC chemokine receptor 2, ANOVA, analysis of variance, STEMI, ST-segment elevation myocardial infarction, I/R, ischemia-reperfusion, ECM, extracellular matrix, LAD, left anterior descending coronary artery, medicine.symptom, Grk2, G protein–coupled receptor kinase 2, Cardiology and Cardiovascular Medicine, Extracellular matrix organization, medicine.medical_specialty, qRT-PCR, quantitative reverse transcription polymerase chain reaction, ischemia-reperfusion injury, Ischemia, Inflammation, Downregulation and upregulation, Cxcl2, CXC chemokine ligand 2, medicine, CLEC4E, LV, left ventricular, CLEC4E, C-type lectin domain family 4 member E, business.industry, medicine.disease, Efna2, ephrin A2, WT, wild-type, ESV, end-systolic volume, AMI, acute myocardial infarction, inflammation, RNA, ribonucleic acid, ACS, acute coronary syndrome, Preclinical Research, hs-TnI, high-sensitivity troponin I, business, Reperfusion injury, MRI, magnetic resonance imaging

وصف الملف: Electronic-eCollection

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a46fac4ecaf99cf50513516da72175Test
https://lirias.kuleuven.be/handle/123456789/680542Test

المؤلفون: June Zhi Xu, James Littrell, Seunghun Paul Lee, Guozhang Xu, Matthew Rankin, Jenson Qi, Ivona Bakaj, Alessandro Pocai

المصدر: Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology

مصطلحات موضوعية: 0301 basic medicine, obesity, insulin secretion, CKD - chronic kidney disease, G-Protein-Coupled Receptor Kinase 1, Endocrinology, Diabetes and Metabolism, Endogeny, GRK2 = G protein–coupled receptor kinase 2, Eating, Mice, 0302 clinical medicine, Endocrinology, Glucagon-Like Peptide 1, Receptors, Glucagon, Insulin, Phosphorylation, Receptor, beta-Arrestins, Original Research, biology, diabetes, Chemistry, Kinase, digestive, oral, and skin physiology, NASH, Glucagon-like peptide-1, Cell biology, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, endocrine system, Dipeptidyl Peptidase 4, CHO Cells, Carbohydrate metabolism, Glucagon-Like Peptide-1 Receptor, Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, Islets of Langerhans, Cricetulus, Diabetes Mellitus, Animals, Humans, Renal Insufficiency, Chronic, Dipeptidyl peptidase-4, G protein-coupled receptor, Beta adrenergic receptor kinase, RC648-665, Amides, 030104 developmental biology, Glucose, biology.protein, Calcium, GLP-1, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440f9f5baedcb64f3b7c2909187f7092Test

المؤلفون: David Garcia-Dorado, Federico Mayor, Javier Inserte, Antonio Rodríguez-Sinovas, Petronila Penela, Paula Ramos

المساهمون: Instituto de Salud Carlos III, Ministerio de Economía, Industria y Competitividad (España), Centro de Investigación Biomédica en Red Enfermedades Cardiovaculares (España), European Commission, Comunidad de Madrid, Fundación Ramón Areces, UAM. Departamento de Biología Molecular, [Penela P, Mayor Jr F] Departamento de Biología Molecular, Centro de Biología Molecular 'Severo Ochoa' (UAM-CSIC), Madrid, Spain. Instituto de Investigación Sanitaria La Princesa, Madrid, Spain. CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain. [Inserte J, Rodriguez-Sinovas A, Garcia-Dorado D] CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain. Grup de Recerca en Malalties Cardiovasculars, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Barcelona, Spain. [Ramos P] Departamento de Biología Molecular, Centro de Biología Molecular 'Severo Ochoa' (UAM-CSIC), Madrid, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
EBioMedicine
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

مصطلحات موضوعية: Male, 0301 basic medicine, Research paper, G-Protein-Coupled Receptor Kinase 2, Swine, Myocardial Ischemia, Cardioprotection, Pharmacology, enfermedades cardiovasculares::enfermedades cardíacas::enfermedades cardiovasculares::enfermedades cardíacas::isquemia miocárdica::enfermedades cardiovasculares::enfermedades cardiovasculares::daño por reperfusión miocárdica [ENFERMEDADES], RISK, reperfusion injury salvage kinase pathway, HF, heart failure, aminoácidos, péptidos y proteínas::péptidos::péptidos y proteínas de señalización intracelular::cinasas de receptores acoplados a proteína G::cinasas de receptores adrenérgicos beta::aminoácidos, péptidos y proteínas::cinasa 2 del receptor acoplado a proteína G [COMPUESTOS QUÍMICOS Y DROGAS], 0302 clinical medicine, Cardiovascular Diseases::Heart Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Cardiovascular Diseases::Cardiovascular Diseases::Myocardial Reperfusion Injury [DISEASES], Phosphorylation, Cells, Cultured, Amino Acids, Peptides, and Proteins::Amino Acids, Peptides, and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::G-Protein-Coupled Receptor Kinases::beta-Adrenergic Receptor Kinases::G-Protein-Coupled Receptor Kinase 2 [CHEMICALS AND DRUGS], biology, Ischemia-reperfusion, Calpain, General Medicine, Reperfusió miocardíaca, Biología y Biomedicina / Biología, metabolismo, 030220 oncology & carcinogenesis, Proteïna quinasa CK2, MI, myocardial infarction, Signal transduction, Oxidation-Reduction, Proteasome Endopeptidase Complex, Ischemia, Calpains, GRK2, G-protein coupled receptor kinase 2, GRK2, Myocardial Reperfusion Injury, Models, Biological, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Pin1, medicine, Animals, Protein kinase B, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Proteasome, business.industry, Beta adrenergic receptor kinase, AKT, metabolism, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, GPCR, G-protein coupled receptor, Proteolysis, biology.protein, I/R, Ischemia/Reperfusion, Models animals en la investigació, Investigative Techniques::Models, Animal::Investigative Techniques::Disease Models, Animal [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], técnicas de investigación::modelos animales::técnicas de investigación::modelos de enfermedad en animales [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], business, Proto-Oncogene Proteins c-akt, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41dad9110403d709ff026f063aca0a1dTest
http://hdl.handle.net/10261/214344Test

المؤلفون: Kai Sun, Jing-Yan Han, Jing-Yu Fan

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 1, Pp 8-24 (2015)

مصطلحات موضوعية: OGD, oxygen-glucose deprivation, MPO, myeloperoxidase, Brain blood barrier, Review, ICAM-1, intercellular adhesion molecule-1, Traditional Chinese medicine, JAM-1, junctional adhesion molecule-1, BNDF, brain-derived neurotrophic factor, ZO-1, zonula occludens-1, Cognitive disabilities, bFGF, basic fibroblast growth factor, ERK, extracellular signal-regulated kinase, GSH, glutathione, RANTES, regulated upon activation normal T-cell expressed and secreted, Asian country, BMEC, brain microvascular endothelial cell, General Pharmacology, Toxicology and Pharmaceutics, IL-8, interleukin-8, ICAM-1, I-κBα, Inhibitory κBα, LDH, lactate dehydrogenase, GRK2, G protein-coupled receptor kinase 2, GSSH, glutathione disulfide, HE, hematoxylin and eosin, Cav-1, caveolin-1, IL-10, interleukin-10, TTC, 2,3,5-triphenyltetrazolium chloride, Hyperpermeability, I/R, ischemia-reperfusion, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, HIF, hypoxia-inducible factor, medicine.anatomical_structure, HPLC, high performance liquid chromatography, COX-2, cyclooxygenase-2, JNK, Jun N-terminal kinase, iNOS, inducible nitric oxide synthase, TBARS, thiobarbituric acid reactive substance, Cardiology, Antioxidant, CBF, cerebral blood flow, TCM, traditional Chinese medicine, Gly, glysine, AIF, apoptosis inducing factor, Perfusion, AP-1, activator protein-1, PARP, poly-ADP-ribose polymerase, Asp, aspartate, medicine.medical_specialty, AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, GSH-Px, glutathione peroxidase, IL-1β, interleukin-1β, NGF, nerve growth factor, rtPA, recombinant tissue plasminogen activator, Ischemia, Materia medica, Ischemia/reperfusion, PMN, polymorphonuclear, BBB, brain blood barrier, 8-OHdG, 8-hydroxydeoxyguanosine, ROS, reactive oxygen species, SOD, superoxide dismutase, Internal medicine, VCAM-1, vascular adhesion molecule-1, medicine, NMDA, N-methyl-d-aspartic acid, NSC, neural stem cells, MCAO, middle cerebral artery occlusion, TNF-α, tissue necrosis factor-α, MDA, malondialdehyde, NO, nitric oxide, Glu, glutamate, business.industry, lcsh:RM1-950, TGF-β1, transforming growth factor β1, Neuron, NADPH, nicotinamide adenine dinucleotide phosphate, NF-κB, nuclear factor κ-B, medicine.disease, Tuj-1, class III β-tublin, hs-CRP, high-sensitivity C-reactive protein, lcsh:Therapeutics. Pharmacology, TIMP-1, tissue inhibitor of metalloproteinase-1, Leukocyte adhesion, TUNEL, terminal-deoxynucleoitidyl transferase mediated nick end labeling, Immunology, MMPs, matrix metalloproteinases, DPPH, 1,1-diphenyl-2-picrylhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl, CAT, catalase, business, DHR, dihydrorhodamine 123, GABA, γ-aminobutyric acid, MRI, magnetic resonance imaging, MAPK, mitogen activated protein kinase, SFDA, state food and drug administration

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a92c082ff55a05b39696b6f1c0e3ba8aTest
https://doi.org/10.1016/j.apsb.2014.11.002Test

المؤلفون: Raffaella Molteni, Ivan de Curtis, Ruggero Pardi, Manuela Gavina, Lorena Za

المصدر: Biology of the Cell

مصطلحات موضوعية: GTPase-activating protein, Cell Cycle Proteins, migration, PAK, p21-activated kinase, GAP, GTPase-activating protein, chemotactic response, Cdc42, cell division cycle 42, Cell Movement, Internalization, Receptor, ARF, ADP-ribosylation factor, media_common, HA, haemagglutinin, Chemotaxis, GTPase-Activating Proteins, GIT, G-protein-coupled-receptor-kinase-interacting protein, Cell migration, General Medicine, Basophils, Cell biology, N-Formylmethionine Leucyl-Phenylalanine, adhesion, GIT–PIX complex, spreading, Research Article, S1, Fluo4/AM, Fluo-4 acetoxymethyl ester, media_common.quotation_subject, Down-Regulation, Motility, Biology, Endocytosis, FPR, fMLP peptide receptor, Cell Line, Tumor, Cell Adhesion, endocytosis, Animals, mAb, monoclonal antibody, Cell Cycle Protein, Cell adhesion, FN, fibronectin, fMLP, formyl-Met-Leu-Phe, PIX, PAK-interacting exchange factor, Cell Biology, Phosphoproteins, GRK2, G-protein-coupled receptor-kinase 2, Rats, p21-Activated Kinases, siRNA, small interfering RNA, Calcium

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f1190268aea9cc607db42582490532Test
https://doi.org/10.1042/bc20090074Test

المؤلفون: Gareth L. Ackland, Svetlana Mastitskaya, Patrick S. Hosford, Alex Dyson, Asif Machhada, Alexander V. Gourine

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Efferent, medicine.medical_treatment, LVEDP, left ventricular end-diastolic pressure, heart failure, ABP, arterial blood pressure, LVESP, left ventricular end-systolic pressure, Stimulation, 030204 cardiovascular system & hematology, Optogenetics, LV dP/dtMAX, maximum rate of rise of left ventricular pressure, vagal nerve stimulation, PRECLINICAL RESEARCH, 03 medical and health sciences, 0302 clinical medicine, DVMN, dorsal motor nucleus of the vagus nerve, Internal medicine, LVV, lentiviral vector, medicine, Myocardial infarction, optogenetics, business.industry, autonomic nervous system, vagus nerve stimulation, medicine.disease, Neuromodulation (medicine), LAD, left anterior descending coronary artery, VNS, vagus nerve stimulation, Autonomic nervous system, myocardial infarction, GRK2, G-protein−coupled receptor kinase 2, LV, left ventricle, 030104 developmental biology, eGFP, enhanced green fluorescent protein, LVP, left ventricular pressure, Heart failure, cardiac contractility, neuromodulation, MI, myocardial infarction, Cardiology, Cardiology and Cardiovascular Medicine, business, Editorial Comment, Vagus nerve stimulation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68f79ec73b22fafafa1cdb6958e38beTest