دورية أكاديمية
Study of the toxic effect of trichothecene mycotoxin produced by Fusarium sporotrichioides in an experiment on pigs ; Изучение токсического действия трихотеценового микотоксина продуцента Fusarium sporotrichioides в опыте на свиньях
| العنوان: | Study of the toxic effect of trichothecene mycotoxin produced by Fusarium sporotrichioides in an experiment on pigs ; Изучение токсического действия трихотеценового микотоксина продуцента Fusarium sporotrichioides в опыте на свиньях |
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| المؤلفون: | I. Idiyatov I., I. Kadikov R., V. Saitov R., G. Kashevarov S., I. Fitsev M., A. Tremasova M., K. Perfilova V., M. Salnikova M., И. Идиятов И., И. Кадиков Р., В. Саитов Р., Г. Кашеваров С., И. Фицев М., А. Тремасова М., К. Перфилова В., М. Сальникова М. |
| المساهمون: | Part of the work was carried out as part of the implementation of grant MK‐1582.2020.11 (Agreement No. 075‐15‐2020‐225 dated 04/27/20), with the involvement of equipment purchased with the support of the Presidential Grants Council of the Russian Federation for state support of young Russian scientists and state support of leading scientific schools of the Russian Federation., Часть работы выполнена в рамках реализации гранта МК‐1582.2020.11 (соглашение № 075‐15‐2020‐225 от 27.04.2020), с привлечением оборудования, приобретенного при поддержке Совета по грантам Президента Российской Федерации для государственной поддержки молодых российских ученых и по государственной поддержке ведущих научных школ Российской Федерации. |
| المصدر: | South of Russia: ecology, development; Том 17, № 1 (2022); 62-79 ; Юг России: экология, развитие; Том 17, № 1 (2022); 62-79 ; 2413-0958 ; 1992-1098 ; 10.18470/1992-1098-2022-1 |
| بيانات النشر: | State Institute of Applied Ecology of the Republic of Dagestan |
| سنة النشر: | 2022 |
| المجموعة: | South of Russia: ecology, development (E-Journal) / Юг России: экология, развитие |
| مصطلحات موضوعية: | Fusarium sporotrichioides, T‐2 toxin, pigs, toxicity, Т‐2 токсин, свиньи, токсичность |
| الوصف: | Aim. To assess the consequences of long‐term consumption by pigs of feed experimentally contaminated with T‐2 toxin in an amount close to the most commonly found in feed.Material and Methods. The experiments were carried out on pigs, which were fed food contaminated with T‐2 toxin in the amount of 200 mkg/kg for 45 days. During the experiment, the clinical condition of animals, feed and water consumption, the dynamics of live weight, analysis of blood parameters, the state of internal organs and tissues and statistical processing of the data obtained by conventional methods were undertaken.Results. Long‐term consumption of feed contaminated with mycotoxin T‐2 by pigs did not cause a pronounced clinical picture of toxicosis. However, the treated animals had diarrhea and lag in growth and development. According to the results of the blood test, it was concluded that the toxin suppressed the hematopoiesis process, inhibited protein synthesis, reduced resistance and microphagocytic function of the body, metabolic disorders and the functioning of most organs and systems. Pathological conditions and degenerative changes of cells and tissues of internal organs were recorded and mediated by the initiation of oxidative stress, inflammatory processes and cytotoxic effect.Conclusions. The consumption of feed contaminated with T‐2 toxin in a dose of 200 mkg /kg by pigs was accompanied by disturbances of metabolic processes, functions of organs and systems, manifested by a decrease in growth intensity, changes in the blood picture, activity of enzyme systems, induction of oxidative stress, immunosuppressive and inflammatory reactions and pathomorphological disorders. Thus, the oral intake of T‐2 toxin, even in small concentrations, was found to have a complex negative effect on the body. ; Цель. Оценить последствия длительного потребления свиньями корма, экспериментально контаминированного Т‐2 токсином в количестве, близком к наиболее часто обнаруживаемому в кормах.Материал и методы. Опыты проводили на свиньях, которым в ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
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| DOI: | 10.18470/1992-1098-2022-1-62-79 |
| الإتاحة: | https://doi.org/10.18470/1992-1098-2022-1-62-79Test https://doi.org/10.18470/1992-1098-2022-1Test https://doi.org/10.1016/j.anifeedsci.2011.12.014Test https://doi.org/10.1088/1755Test‐1315/663/1/012047 https://doi.org/10.3390/toxins11070375Test https://doi.org/10.1088/1755Test‐1315/723/2/022022 https://doi.org/10.1007/s00204Test‐014‐1309‐4 https://doi.org/10.1111/1541Test‐4337.12029 https://doi.org/10.17221/156/2009Test‐VETMED https://doi.org/10.2478/pjvsTest‐2013‐0046 |
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| رقم الانضمام: | edsbas.1831424D |
| قاعدة البيانات: | BASE |
| DOI: | 10.18470/1992-1098-2022-1-62-79 |
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