يعرض 1 - 10 نتائج من 24,740 نتيجة بحث عن '"G-protein-coupled receptors"', وقت الاستعلام: 1.21s تنقيح النتائج
  1. 1
    دورية أكاديمية
    GPCR-IPL score: multilevel featurization of GPCR–ligand interaction patterns and prediction of ligand functions from selectivity to biased activation.

    المؤلفون: Kumar, Surendra1 (AUTHOR), Teli, Mahesh K1 (AUTHOR), Kim, Mi-hyun1 (AUTHOR) kmh0515@gachon.ac.kr

    المصدر: Briefings in Bioinformatics. Mar2024, Vol. 25 Issue 2, p1-17. 17p.

    مصطلحات موضوعية: LIGAND binding (Biochemistry), G protein coupled receptors, RECEIVER operating characteristic curves, STRUCTURE-activity relationships, ARRESTINS, CELL communication


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  2. 2
    دورية أكاديمية
    Molecular insights into orphan G protein‐coupled receptors relevant to schizophrenia.

    المؤلفون: Lu, Yao1,2 (AUTHOR), Hatzipantelis, Cassandra J.3 (AUTHOR), Langmead, Christopher J.1,2,4,5 (AUTHOR) chris.langmead@monash.edu, Stewart, Gregory D.1,2,4,5 (AUTHOR) gregory.stewart@monash.edu

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2095-2113. 19p.

    مصطلحات موضوعية: *G protein coupled receptors, *DOPAMINE receptors, *MUSCARINIC receptors, *SCHIZOPHRENIA, *ORPHANS, *SMALL molecules, *CELL physiology


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  3. 3
    دورية أكاديمية
    The application of artificial intelligence to accelerate G protein‐coupled receptor drug discovery.

    المؤلفون: Nguyen, Anh T. N.1 (AUTHOR), Nguyen, Diep T. N.2 (AUTHOR), Koh, Huan Yee1,3 (AUTHOR), Toskov, Jason4 (AUTHOR), MacLean, William4 (AUTHOR), Xu, Andrew4 (AUTHOR), Zhang, Daokun1,3 (AUTHOR), Webb, Geoffrey I.3 (AUTHOR), May, Lauren T.1 (AUTHOR) lauren.may@monash.edu, Halls, Michelle L.1 (AUTHOR) michelle.halls@monash.edu

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2371-2384. 14p.

    مصطلحات موضوعية: *DRUG discovery, *G protein coupled receptors, *ARTIFICIAL intelligence, *DRUG receptors, *DEEP learning, *MACHINE learning, *INTELLIGENCE sharing


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  4. 4
    دورية أكاديمية
    Highlights and hot topics in GPCR research from 'Down Under'.

    المؤلفون: Smith, Nicola J.1 (AUTHOR) nicola.smith@unsw.edu.au, May, Lauren T.2 (AUTHOR) lauren.may@monash.edu, Grimsey, Natasha L.3,4,5 (AUTHOR) n.grimsey@auckland.ac.nz

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2091-2094. 4p.

    مصطلحات موضوعية: *G protein coupled receptors, *SECOND messengers (Biochemistry), *TOXICOLOGISTS


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  5. 5
    دورية أكاديمية
    RAMP and MRAP accessory proteins have selective effects on expression and signalling of the CB1, CB2, GPR18 and GPR55 cannabinoid receptors.

    المؤلفون: Glenn, Nathaniel A. K.1,2 (AUTHOR), Finlay, David B.3 (AUTHOR), Carruthers, Emma R.1,2,4 (AUTHOR), Mountjoy, Kathleen G.2,4,5 (AUTHOR), Walker, Christopher S.4,6 (AUTHOR), Grimsey, Natasha L.1,2,4 (AUTHOR) n.grimsey@auckland.ac.nz

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2212-2231. 20p.

    مصطلحات موضوعية: *CANNABINOID receptors, *G protein coupled receptors, *MELANOCORTIN receptors, *PEPTIDES, *PROTEIN receptors, *G proteins


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  6. 6
    دورية أكاديمية
    The application of targeted protein degradation technologies to G protein‐coupled receptors.

    المؤلفون: Keen, Alastair C.1 (AUTHOR) alastair.keen1@monash.edu, Jörg, Manuela2,3 (AUTHOR), Halls, Michelle L.1 (AUTHOR) michelle.halls@monash.edu

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2351-2358. 8p.

    مصطلحات موضوعية: *PROTEOLYSIS, *G protein coupled receptors, *DRUG target, *MEMBRANE proteins


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  7. 7
    دورية أكاديمية
    The role of the adenosine system in epilepsy and its comorbidities.

    المؤلفون: Baltos, Jo‐Anne1 (AUTHOR), Casillas‐Espinosa, Pablo M.2,3,4 (AUTHOR), Rollo, Ben2 (AUTHOR), Gregory, Karen J.1,5 (AUTHOR), White, Paul J.1 (AUTHOR), Christopoulos, Arthur1,6 (AUTHOR), Kwan, Patrick2,3,4,7 (AUTHOR), O'Brien, Terence J.2,3,4,7 (AUTHOR), May, Lauren T.1 (AUTHOR) lauren.may@monash.edu

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2143-2157. 15p.

    مصطلحات موضوعية: *ADENOSINES, *G protein coupled receptors, *CARDIOVASCULAR diseases, *NEUROLOGICAL disorders, *COMORBIDITY, *PEOPLE with epilepsy


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  8. 8
    دورية أكاديمية
    Unravelling G protein‐coupled receptor signalling networks using global phosphoproteomics.

    المؤلفون: Pokhrel, Rina1 (AUTHOR), Morgan, Alexandra L.1 (AUTHOR), Robinson, Harley R.2 (AUTHOR), Stone, Martin J.1 (AUTHOR) martin.stone@monash.edu, Foster, Simon R.2,3 (AUTHOR) simon.foster@qimrberghofer.edu.au

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2359-2370. 12p.

    مصطلحات موضوعية: *G protein coupled receptors, *DRUG receptors, *PROTEOMICS, *DRUG discovery, *CELLULAR signal transduction


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  9. 9
    دورية أكاديمية
    Mas‐related G protein‐coupled receptors in gastrointestinal dysfunction and inflammatory bowel disease: A review.

    المؤلفون: Hawker, Patrick1 (AUTHOR), Zhang, Li2 (AUTHOR), Liu, Lu1 (AUTHOR) lu.liu@unsw.edu.au

    المصدر: British Journal of Pharmacology. Jul2024, Vol. 181 Issue 14, p2197-2211. 15p.

    مصطلحات موضوعية: *G protein coupled receptors, *INFLAMMATORY bowel diseases, *GASTROINTESTINAL system, *ENTERIC nervous system


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  10. 10
    دورية أكاديمية
    Building the Glucagon-Like Peptide-1 Receptor Brick by Brick: Revisiting a 1993 Diabetes Classic by Thorens et al.

    المؤلفون: Thorens, Bernard1 (AUTHOR) bernard.thorens@unil.ch, Hodson, David J.2 (AUTHOR) david.hodson@ocdem.ox.ac.uk

    المصدر: Diabetes. Jul2024, Vol. 73 Issue 7, p1027-1031. 5p.

    مصطلحات موضوعية: *GLUCAGON-like peptide-1 receptor, *G protein coupled receptors, *CHEMICAL biology, *TYPE 2 diabetes, *HUMAN genetics


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