المؤلفون: Birgitta Karlsson Svalstedt, Anders Thelin, Annika Wellner, Johanna Vinblad, Margareta Herslöf, David Gustafsson, Yantao Chen, Cristian Bodin, Ola Fjellström, Stefan Blaho, Jenny Sandmark, Carina Johansson, Birgitta Rosengren, Sofia Martinsson, Tomas Fex, Jonas Boström, Andreas Moberg, Tomas Akerud, Emma Evertsson, Bingze Xu, Ryan Hicks, Magnus Althage, Emelie Jarkvist, Wolfgang Knecht, Per-Olof Eriksson, Marianne Ridderström, Ann-Margret Östlund-Lindqvist, Anna Tigerström, Anders Dahlén, Anne Legnehed, Thomas Antonsson, Alan Sabirsh, Inge Kalies, Fredrik Kartberg

المصدر: J Biol Chem

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Apolipoprotein B, Plasmin, Lysine, Sequence Homology, Ligands, Biochemistry, Kringle domain, Small Molecule Libraries, 03 medical and health sciences, Kringles, Protein Domains, medicine, Humans, Amino Acid Sequence, Molecular Biology, Apolipoproteins A, Fibrin, 030102 biochemistry & molecular biology, biology, Ligand, Chemistry, Cell growth, Molecular Bases of Disease, Cell Biology, Small molecule, High-Throughput Screening Assays, 030104 developmental biology, biology.protein, lipids (amino acids, peptides, and proteins), Protein Binding, medicine.drug, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb534512cdcc56630f05e52c97ed62aTest
https://doi.org/10.1074/jbc.ra119.011251Test

المؤلفون: Paul H. Weinreb, Lary C. Walker, Matthias Staufenbiel, Ruth E. Uhlmann, Rawaa Al-Shaana, Emily M. Ullrich Gavilanes, Søren Christensen, Frank Baumann, Ulrike Obermüller, Stephan A. Kaeser, Fredrik Kartberg, Mathias Jucker, Angelos Skodras, Jay Rasmussen, Holger Cynis, Lan Ye, Anika Buehler, Fang Qian, Carina Bergmann, Juliane Schelle, Sarah K. Fritschi, Thierry Bussiere, Jens-Ulrich Rahfeld, Christine Rother, Natalie Beschorner, Jeffrey B. Stavenhagen

المساهمون: Publica

المصدر: Nat Neurosci
Nature neuroscience 23(12), 1580-1588 (2020). doi:10.1038/s41593-020-00737-w

مصطلحات موضوعية: 0301 basic medicine, Male, pharmacology [Tissue Extracts], pharmacokinetics [Antibodies, Monoclonal, Humanized], Plaque, Amyloid, Protein aggregation, pharmacology [Antibodies, Monoclonal, Humanized], neuroscience, pathology [Alzheimer Disease], Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Neurofilament Proteins, antagonists & inhibitors [Amyloid beta-Protein Precursor], Aged, 80 and over, biology, Chemistry, General Neuroscience, aducanumab, Middle Aged, Alzheimer's disease, Cell biology, Aducanumab, Antibody, pharmacology [Antibodies, Blocking], metabolism [Alzheimer Disease], Genetically modified mouse, Amyloid, Immunoprecipitation, Transgene, metabolism [Amyloid beta-Peptides], Mice, Transgenic, Antibodies, Monoclonal, Humanized, Article, 03 medical and health sciences, In vivo, Alzheimer Disease, Animals, Humans, ddc:610, pathology [Plaque, Amyloid], Antibodies, Blocking, Aged, Brain Chemistry, Amyloid beta-Peptides, Tissue Extracts, cerebrospinal fluid [Neurofilament Proteins], Mice, Inbred C57BL, 030104 developmental biology, biology.protein, diseases of the nervous system, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304ff0cfb27901cbd3f5fac431ae6943Test
https://publica.fraunhofer.de/handle/publica/269747Test

المؤلفون: Lennart Asp, Fredrik Kartberg, Julia Fern, Maria Smedh, Markus Elsner, Frederic Laporte, Karen A. Jansen, Tommy Nilsson

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633395/pdf/zmk780.pdfTest.

مصطلحات موضوعية: Weiss and Nilsson, Bethune et al, 2006). For

الوقت: 2003

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.666.4313Test; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633395/pdf/zmk780.pdfTest

الإتاحة: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633395/pdf/zmk780.pdfTest

المؤلفون: Sarah K. Fritschi, Matthias Staufenbiel, Lary C. Walker, Anika Buehler, Ulrike Obermüller, Juliane Schelle, Christine Rother, Ruth E. Uhlmann, Mathias Jucker, Jay Rasmussen, Fredrik Kartberg, Stephan A. Kaeser, Jeffrey B. Stavenhagen, Emily M. Ullrich-Gavilanes, Holger Cynis, Søren Christensen, Frank Baumann

المصدر: Alzheimer's & Dementia. 15

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Amyloid disease, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology, Biology, Microbiology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::784dcbf4f6976d6ea696757c7107e324Test
https://doi.org/10.1016/j.jalz.2019.09.054Test

المؤلفون: Karsten Skjødt, Jan Egebjerg, Jan Torleif Pedersen, Fredrik Kartberg, Christiane Volbracht, Florence Sotty, Nina Helen Rosenqvist, Lars Østergaard Pedersen, Einar M. Sigurdsson, Ayodeji A. Asuni, Pia Jul, Christian Rungsted Andersson, Jeppe Falsig, Lone Helboe, Jeffrey B. Stavenhagen, Justus Claus Alfred Daechsel, Søren Christensen

المصدر: Alzheimer's & Dementia : Translational Research & Clinical Interventions
Rosenqvist, N, Asuni, A A, Andersson, C R, Christensen, S, Daechsel, J A, Egebjerg, J, Falsig, J, Helboe, L, Jul, P, Kartberg, F, Pedersen, L Ø, Sigurdsson, E M, Sotty, F, Skjødt, K, Stavenhagen, J B, Volbracht, C & Pedersen, J T 2018, ' Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tau ', Alzheimer's & Dementia: Translational Research & Clinical Interventions, vol. 4, pp. 521-534 . https://doi.org/10.1016/j.trci.2018.09.005Test

مصطلحات موضوعية: 0301 basic medicine, Monoclonal antibody, medicine.drug_class, Tau protein, Hyperphosphorylation, Anti-tau antibodies, C10.2, Peptide, D1.2, 03 medical and health sciences, 0302 clinical medicine, C8.3, Tau seeding, mental disorders, medicine, IC50, chemistry.chemical_classification, biology, HEK 293 cells, Neurodegeneration, Featured Article, medicine.disease, Phospho-serine 396, C5.2, Cell biology, Psychiatry and Mental health, 030104 developmental biology, chemistry, biology.protein, Neurology (clinical), Antibody, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4e509d5c60e3458f1a368b67631b5aTest
https://pubmed.ncbi.nlm.nih.gov/30386817Test

المؤلفون: Fredrik Kartberg, Søren Christensen, Kasper D. Rand, Ziqian Wan, Nadia Abu-Asad, Esben Trabjerg

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Recombinant Fusion Proteins, Genetic Vectors, Gene Expression, Hydrogen Deuterium Exchange-Mass Spectrometry, Peptide, Crystallography, X-Ray, Ligands, 03 medical and health sciences, chemistry.chemical_compound, Progranulins, 0302 clinical medicine, Structural Biology, Cell surface receptor, Neurotrophic factors, Nerve Growth Factor, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Cloning, Molecular, Protein Precursors, Binding site, Receptor, Protein precursor, Molecular Biology, Neurotensin, Glutathione Transferase, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, 030302 biochemistry & molecular biology, Transmembrane protein, 3. Good health, Adaptor Proteins, Vesicular Transport, HEK293 Cells, chemistry, Biophysics, Protein Conformation, beta-Strand, 030217 neurology & neurosurgery, Protein Binding, Protein ligand

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba77b31a1c223e89b410dba1da1ff371Test

المؤلفون: Fredrik Kartberg, Josefine Claesson, Brian Middleton, David I Fisher, W. Mark Abbott, Robert G. Roth

المصدر: Protein Expression and Purification. 116:113-119

مصطلحات موضوعية: Chinese hamster ovary cell, HEK 293 cells, Cell Culture Techniques, Gene Expression, Heterologous, CHO Cells, DNA, Transfection, Biology, Molecular biology, law.invention, Cell biology, Bioreactors, Cricetulus, law, Cell culture, Gene expression, Recombinant DNA, Bioreactor, Animals, Polyethyleneimine, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acacb9dd4538db291e167372bcf9fefeTest
https://doi.org/10.1016/j.pep.2015.08.016Test

المؤلفون: Martin J. Glennie, Jeffrey B. Stavenhagen, Fredrik Kartberg, Jessica L. Teeling, James P. Fuller, Søren Christensen

المصدر: Acta Neuropathologica

مصطلحات موضوعية: Neuroimmunomodulation, Amyloid beta, Interleukin-1beta, Drug Evaluation, Preclinical, Clinical Neurology, Antigens, Differentiation, Myelomonocytic, Mice, Transgenic, Plaque, Amyloid, Inflammation, Antibodies, Monoclonal, Humanized, Hippocampus, Cell Line, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Bapineuzumab, Alzheimer Disease, Antigens, CD, Crenezumab, Animals, Humans, Immunologic Factors, Medicine, Neuroinflammation, Original Paper, Amyloid beta-Peptides, CD11b Antigen, Microglia, biology, Tumor Necrosis Factor-alpha, business.industry, Antibodies, Monoclonal, medicine.disease, Gantenerumab, medicine.anatomical_structure, Immunology, biology.protein, Female, Immunotherapy, Neurology (clinical), medicine.symptom, Alzheimer's disease, business, Alzheimer’s disease, medicine.drug

وصف الملف: text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb42dace76418fc12871074b9b536f64Test
https://doi.org/10.1007/s00401-015-1484-2Test

المؤلفون: Esben Trabjerg, Søren Christensen, Kasper D. Rand, Fredrik Kartberg

مصطلحات موضوعية: 0301 basic medicine, Nervous system, Receptor complex, Glycosylation, Stereochemistry, Crystallography, X-Ray, Biochemistry, Protein Structure, Secondary, 03 medical and health sciences, Protein structure, Protein Domains, Nerve Growth Factor, medicine, Humans, Protein Precursors, Receptor, Molecular Biology, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, Protein Stability, Neurodegeneration, Deuterium Exchange Measurement, Cell Biology, medicine.disease, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Nerve growth factor, chemistry, nervous system, biology.protein, Glycoprotein, Molecular Biophysics, Neurotrophin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a4d6da809b064581fc314a736d5d5fTest
https://europepmc.org/articles/PMC5633128Test/

المؤلفون: Maria Smedh, Tommy Nilsson, Fredrik Kartberg, John F. Presley, Selma Yilmaz Dejgaard, Lennart Asp, Julia Fernandez-Rodriguez

المصدر: Journal of Biological Chemistry. 285:36709-36720

مصطلحات موضوعية: Golgi Apparatus, Biology, Biochemistry, Coat Protein Complex I, Immunoenzyme Techniques, Vesicle uncoating, Humans, RNA, Small Interfering, Molecular Biology, COPII, Secretory pathway, Golgi membrane, ADP-Ribosylation Factors, Vesicular-tubular cluster, Vesicle, GTPase-Activating Proteins, Intracellular Membranes, Cell Biology, COPI, Cell biology, Protein Transport, Coatomer, ADP-Ribosylation Factor 1, Guanosine Triphosphate, COP-Coated Vesicles, HeLa Cells, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8bcc02652655118156a7a2910a19a9Test
https://doi.org/10.1074/jbc.m110.180380Test