التفاصيل البيبلوغرافية
| العنوان: |
Treatment strategies in axial spondyloarthritis: What, when and how? |
| المؤلفون: |
Fragoulis, G.E. Siebert, S. |
| سنة النشر: |
2020 |
| الوصف: |
There have been major advances in the management of axial spondyloarthritis (axSpA) with the introduction of effective biologic agents targeting TNF and IL-17A. Clinicians now have more choice but, despite treatment recommendations, are still faced with significant uncertainty when deciding on the optimal treatment strategy for an individual patient in clinical practice. Management of axSpA typically requires both non-pharmacological and pharmacological interventions. NSAIDs remain the first line drug therapies for axSpA with proven efficacy for symptomatic management but uncertainty remains regarding their optimal long-term use relating to radiographic progression and safety in axSpA. To-date there are no head-to-head trials of biologics in axSpA. Clinicians need to consider other factors, including extra-articular manifestations, comorbidities, safety and radiographic progression when deciding on which biologic to recommend for an individual patient. This article will explore the evidence relating to these factors and highlight areas of unmet need. © 2020 The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. |
| اللغة: |
English |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=od______2127::463a339e13fb99b9c29365bcaaea3d74Test
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3103767Test |
| حقوق: |
OPEN |
| رقم الانضمام: |
edsair.od......2127..463a339e13fb99b9c29365bcaaea3d74 |
| قاعدة البيانات: |
OpenAIRE |
