يعرض 1 - 10 نتائج من 29 نتيجة بحث عن '"Frédéric Vanhoutte"', وقت الاستعلام: 1.08s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first‐in‐human phase I study

    المؤلفون: Andrew Gewitz, Jeanne Mendell, Yuhuan Wang, Charles Harris, Benjamin A. Olenchock, Simona Podgrabinska, Wenjun Zheng, An Zhao, Hao Pan, Frédéric Vanhoutte, John D. Davis

    المصدر: Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)

    مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

    وصف الملف: electronic resource

    العلاقة: https://doaj.org/toc/1752-8054Test; https://doaj.org/toc/1752-8062Test

    الوصول الحر: https://doaj.org/article/3a53c650addb4dff9fd51a0f804d2d33Test

    View record in DOAJ النص الكامل

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  2. 2
    دورية أكاديمية
    Safety and immunogenicity of the measles vector-based SARS-CoV-2 vaccine candidate, V591, in adults: results from a phase 1/2 randomised, double-blind, placebo-controlled, dose-ranging trial

    المؤلفون: Frédéric Vanhoutte, Wen Liu, Richard T. Wiedmann, Liesbeth Haspeslagh, Xin Cao, Keith Boundy, Antonios Aliprantis, Michelle Davila, Jonathan Hartzel, Jianing Li, Mac McGuire, Katrin Ramsauer, Yvonne Tomberger, Roland Tschismarov, Deborah D. Brown, Weifeng Xu, Jeffrey R. Sachs, Kevin Russell, S. Aubrey Stoch, Eseng Lai

    المصدر: EBioMedicine, Vol 75, Iss , Pp 103811- (2022)

    مصطلحات موضوعية: COVID-19, SARS-CoV-2, Vaccine, Medicine, Medicine (General), R5-920

    وصف الملف: electronic resource

    العلاقة: http://www.sciencedirect.com/science/article/pii/S2352396421006058Test; https://doaj.org/toc/2352-3964Test

    الوصول الحر: https://doaj.org/article/d59aa9653c964fe6ac6e01ea17db7d32Test

    View record in DOAJ النص الكامل

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  3. 3
    Sputum induction for assessment of biomarkers in early respiratory drug development

    المؤلفون: Lien Gheyle, Muriel Lins, Haiko Pillu, Frédéric Vanhoutte, Annick van Riel, Robert Lins

    المصدر: Int. Journal of Clinical Pharmacology and Therapeutics. 57:20-23

    مصطلحات موضوعية: Pharmacology, Reproducibility, medicine.medical_specialty, integumentary system, business.industry, Sample processing, Sputum, Healthy subjects, Reproducibility of Results, medicine.disease, Gastroenterology, Asthma, Drug Development, Drug development, Internal medicine, medicine, Humans, Biomarker (medicine), Pharmacology (medical), Respiratory system, medicine.symptom, business, Biomarkers

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1fabfb020dac047c0dc123f2b0f15dTest
    https://doi.org/10.5414/cp203294Test


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  4. 4
    Pharmacokinetics and Pharmacodynamics of Garetosmab (Anti-Activin A): Results From a First-in-Human Phase 1 Study

    المؤلفون: Su Liang, Richard DelGizzi, Tiera Drewery, An Zhao, Marcella Ruddy, Yuhuan Wang, Manoj Rajadhyaksha, Frédéric Vanhoutte, Gary Herman, John D. Davis, Eduardo Forleo-Neto

    المصدر: Journal of Clinical Pharmacology

    مصطلحات موضوعية: Injections, Subcutaneous, Pharmacokinetics/Pharmacodynamics, Pharmacology, Placebo, Pharmacokinetics, Double-Blind Method, fibrodysplasia ossificans progressiva, Medicine, Humans, Immunologic Factors, Pharmacology (medical), In patient, garetosmab, NON COVID ARTICLES, Time zero, business.industry, clinical trial, First in human, medicine.disease, Antibodies, Neutralizing, Healthy Volunteers, Activins, Activin a, Safety profile, monoclonal antibody, Fibrodysplasia ossificans progressiva, Area Under Curve, Administration, Intravenous, Female, activin A, business

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0a38d2104a39535372d06486336ac2Test
    https://pubmed.ncbi.nlm.nih.gov/32557665Test


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  5. 5
    Randomized study of the effect of gadopiclenol, a new gadolinium‐based contrast agent, on the QTc interval in healthy subjects

    المؤلفون: Mathieu Felices, Pascal Voiriot, Frédéric Vanhoutte, Corinne Dubourdieu, Christian Funck-Brentano, Nathalie Le Fur, Pierre Desché

    المساهمون: Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service de pharmacologie médicale [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

    المصدر: British Journal of Clinical Pharmacology
    British Journal of Clinical Pharmacology, Wiley, In press, ⟨10.1111/bcp.14309⟩
    Br J Clin Pharmacol

    مصطلحات موضوعية: Male, medicine.medical_specialty, gadopiclenol, Contrast Media, Gadolinium, QTc interval, Placebo, thorough QT study, 030226 pharmacology & pharmacy, QT interval, 03 medical and health sciences, Electrocardiography, 0302 clinical medicine, Double-Blind Method, Moxifloxacin, Heart Rate, Internal medicine, Medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Adverse effect, osmolarity, Pharmacology, Proarrhythmia, Cross-Over Studies, Dose-Response Relationship, Drug, business.industry, Assay sensitivity, Original Articles, medicine.disease, Crossover study, Confidence interval, Healthy Volunteers, 3. Good health, Long QT Syndrome, healthy subjects, Cardiology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Female, business, Azabicyclo Compounds, medicine.drug, Fluoroquinolones

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39067ff3463c37fc05c63e7f390e0bdTest
    https://hal.sorbonne-universite.fr/hal-02875281Test


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  6. 6
    Safety, Pharmacokinetics, and Antiviral Activity of AT-527, a Novel Purine Nucleotide Prodrug, in Hepatitis C Virus-Infected Subjects with or without Cirrhosis

    المؤلفون: X.J. Zhou, Steven S. Good, Robert L. Murphy, Adel Moussa, Pieter Jan Berghmans, Frédéric Vanhoutte, Elina Berliba, Maxim Bogus, Keith Pietropaolo, Jean Pierre Sommadossi

    المصدر: Antimicrobial Agents and Chemotherapy. 63

    مصطلحات موضوعية: Pharmacology, 0303 health sciences, Cirrhosis, Sofosbuvir, 030306 microbiology, business.industry, Hepatitis C virus, Prodrug, medicine.disease, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, Infectious Diseases, Pharmacokinetics, chemistry, Genotype, medicine, Pharmacology (medical), business, Nucleoside, NS5B, 030304 developmental biology, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cb2c03b3c75752d03aaace12aaa9a828Test
    https://doi.org/10.1128/aac.01201-19Test


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  7. 7
    Safety, pharmacokinetics and antiviral activity of AT-527, a novel purine nucleotide prodrug, in HCV-infected subjects with and without cirrhosis

    المؤلفون: Elina, Berliba, Maxim, Bogus, Frédéric, Vanhoutte, Pieter-Jan, Berghmans, Steven S, Good, Adel, Moussa, Keith, Pietropaolo, Robert L, Murphy, Xiao-Jian, Zhou, Jean-Pierre, Sommadossi

    المصدر: Antimicrobial Agents and Chemotherapy

    مصطلحات موضوعية: pangenotypic, direct-acting antiviral, viruses, cirrhosis, chronic hepatitis C virus infection, virus diseases, nucleotide, Antiviral Agents, NS5B, digestive system diseases

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c650c660583fcc16797347d17f085589Test
    https://pubmed.ncbi.nlm.nih.gov/31570394Test


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  8. 8
    Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK‐1 Inhibitor, After Short‐Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials

    المؤلفون: Mykola Stanislavchuk, Frédéric Vanhoutte, Minodora Mazur, Rene Galien, L. Meuleners, Oleksandr Voloshyn, Florence Namour, Annegret Van der Aa, Gerben van ’t Klooster

    المصدر: Arthritis & Rheumatology (Hoboken, N.j.)

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Filgotinib, Pyridines, Immunology, Arthritis, Rheumatoid Arthritis, Pharmacology, Neutropenia, Placebo, Arthritis, Rheumatoid, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rheumatology, Pharmacokinetics, medicine, Humans, Immunology and Allergy, Aged, 030203 arthritis & rheumatology, business.industry, Janus Kinase 1, Middle Aged, Triazoles, medicine.disease, C-Reactive Protein, Methotrexate, Treatment Outcome, 030104 developmental biology, Antirheumatic Agents, Rheumatoid arthritis, Pharmacodynamics, Drug Therapy, Combination, Female, business, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f7de209ab9f04a13f6a7cc674af718Test
    https://doi.org/10.1002/art.40186Test


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  9. 9
    Filgotinib (GLPG0634/GS-6034), an oral selective JAK1 inhibitor, is effective as monotherapy in patients with active rheumatoid arthritis: results from a randomised, dose-finding study (DARWIN 2)

    المؤلفون: O V Reshetko, Joel M. Kremer, A. Kavanaugh, A Van der Aa, L. Ponce, Chantal Tasset, P. Harrison, R. Cseuz, Maria Greenwald, Mykola Stanislavchuk, Frédéric Vanhoutte

    المصدر: Annals of the Rheumatic Diseases. 76:1009-1019

    مصطلحات موضوعية: Male, medicine.medical_specialty, Filgotinib, Pyridines, Immunology, Administration, Oral, Infections, Placebo, Severity of Illness Index, General Biochemistry, Genetics and Molecular Biology, Arthritis, Rheumatoid, Disability Evaluation, Hemoglobins, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rheumatology, Surveys and Questionnaires, Internal medicine, JAK1 Inhibitor, Clinical endpoint, Humans, Immunology and Allergy, Medicine, In patient, Protein Kinase Inhibitors, 030203 arthritis & rheumatology, Dose-Response Relationship, Drug, business.industry, Janus Kinase 1, Middle Aged, Triazoles, medicine.disease, Surgery, C-Reactive Protein, Methotrexate, Treatment Outcome, Antirheumatic Agents, 030220 oncology & carcinogenesis, Rheumatoid arthritis, Retreatment, Female, business, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975abe0e4dddd80e4e635854aa7c4e60Test
    https://doi.org/10.1136/annrheumdis-2016-210105Test


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  10. 10
    Filgotinib (GLPG0634/GS-6034), an oral JAK1 selective inhibitor, is effective in combination with methotrexate (MTX) in patients with active rheumatoid arthritis and insufficient response to MTX: results from a randomised, dose-finding study (DARWIN 1)

    المؤلفون: Chantal Tasset, Minodora Mazur, P. Harrison, Frédéric Vanhoutte, F. Enriquez-Sosa, Maria Greenwald, Rieke Alten, Rene Westhovens, Peter C. Taylor, D. Pavlova, A Van der Aa

    المصدر: Annals of the Rheumatic Diseases. 76:998-1008

    مصطلحات موضوعية: Male, musculoskeletal diseases, medicine.medical_specialty, Filgotinib, Pyridines, Immunology, Administration, Oral, Infections, Placebo, Severity of Illness Index, General Biochemistry, Genetics and Molecular Biology, Arthritis, Rheumatoid, Disability Evaluation, Hemoglobins, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rheumatology, Surveys and Questionnaires, Internal medicine, medicine, Clinical endpoint, Humans, Immunology and Allergy, Adverse effect, Protein Kinase Inhibitors, 030203 arthritis & rheumatology, Dose-Response Relationship, Drug, biology, business.industry, C-reactive protein, Janus Kinase 1, Middle Aged, Triazoles, medicine.disease, Surgery, C-Reactive Protein, Methotrexate, Antirheumatic Agents, 030220 oncology & carcinogenesis, Rheumatoid arthritis, biology.protein, Drug Therapy, Combination, Female, business, medicine.drug

    وصف الملف: Print-Electronic; application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79f3ec3652efbe8149a5f40badf7560Test
    https://doi.org/10.1136/annrheumdis-2016-210104Test


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