المؤلفون: Asma Ettahar, Olivier Ferrigno, Ming-Zhu Zhang, Mutsuko Ohnishi, Nathalie Ferrand, Céline Prunier, Laurence Levy, Marie-Françoise Bourgeade, Ivan Bieche, Damian G. Romero, Frédéric Colland, Azeddine Atfi

المصدر: Cell Reports, Vol 4, Iss 3, Pp 530-541 (2013)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124713003562Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/7df0852ea2e145babc72f4f55e903569Test

المؤلفون: Szabolcs Sipos (9600207), Balázs Bálint (1417288), Zoltán B. Szabó (1417297), Levente Ondi (1417303), Márton Csékei (7036181), Zoltán Szlávik (11288705), Ágnes Proszenyák (11288708), James B. Murray (11336), James Davidson (6726209), Ijen Chen (6726212), Pawel Dokurno (2188936), Allan E. Surgenor (2188933), Christopher Pedder (6726215), Roderick E. Hubbard (19472), Ana-Leticia Maragno (9600231), Maia Chanrion (698420), Frederic Colland (7036199), Olivier Geneste (508750), András Kotschy (1417294)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Evolutionary Biology, Ecology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, core structure, efficacy studies, deep-S 2 pocket, core replacement analogues, vivo PD response, hit-to-lead optimization, affinity, X-ray-guided S-N replacement, MCL -1, Core Replacement, compound, core swap analogues, tumor growth

العلاقة: https://figshare.com/articles/journal_contribution/The_Effect_of_Core_Replacement_on_S64315_a_Selective_MCL_1_Inhibitor_and_Its_Analogues/15185936Test

الإتاحة: https://doi.org/10.1021/acsomega.1c02595.s002Test

المؤلفون: Szabolcs Sipos, Balázs Bálint, Zoltán B. Szabó, Levente Ondi, Márton Csékei, Zoltán Szlávik, Ágnes Proszenyák, James B. Murray, James Davidson, Ijen Chen, Pawel Dokurno, Allan E. Surgenor, Christopher Pedder, Roderick E. Hubbard, Ana-Leticia Maragno, Maia Chanrion, Frederic Colland, Olivier Geneste, András Kotschy

المصدر: ACS Omega, Vol 6, Iss 34, Pp 22073-22102 (2021)

مصطلحات موضوعية: Chemistry, QD1-999

العلاقة: https://doi.org/10.1021/acsomega.1c02595Test; https://doaj.org/toc/2470-1343Test; https://doaj.org/article/8920fac56cd04386b0126955f672d5f2Test

الإتاحة: https://doi.org/10.1021/acsomega.1c02595Test
https://doaj.org/article/8920fac56cd04386b0126955f672d5f2Test

المؤلفون: Laurent Daviet, Rémi Delansorne, Philippe Guedat, Jean-Christophe Rain, Guillaume Boissy, Vincent Collura, Wolfgang Sippl, Catherine Borg-Capra, Alessandra Calabrese, Jacques Camonis, Vasily N. Aushev, Julie Bianchi, Virginie Trouplin, Susan Conrath, Cécile Planquette, Céline Reverdy, Xavier Jacq, Etienne Formstecher, Frédéric Colland

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b7c9eb0a78d607a3ed0a2185eba838Test
https://doi.org/10.1158/1535-7163.c.6532221.v1Test

المؤلفون: Laurent Daviet, Rémi Delansorne, Philippe Guedat, Jean-Christophe Rain, Guillaume Boissy, Vincent Collura, Wolfgang Sippl, Catherine Borg-Capra, Alessandra Calabrese, Jacques Camonis, Vasily N. Aushev, Julie Bianchi, Virginie Trouplin, Susan Conrath, Cécile Planquette, Céline Reverdy, Xavier Jacq, Etienne Formstecher, Frédéric Colland

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e51112a679de8e29abcc1e35e6f3f6Test
https://doi.org/10.1158/1535-7163.22486059Test

المؤلفون: I-Jen Chen, Proszenyák Ágnes, Zoltán B. Szabó, Levente Ondi, Csékei Márton, Olivier Geneste, Szabolcs Sipos, Allan E. Surgenor, Frédéric Colland, C. Pedder, Maïa Chanrion, Balázs Bálint, Ana-Leticia Maragno, Roderick E. Hubbard, Szlávik Zoltán, Pawel Dokurno, András Kotschy, James B. Murray, James R. Davidson

المصدر: ACS Omega, Vol 6, Iss 34, Pp 22073-22102 (2021)
ACS Omega

مصطلحات موضوعية: Cellular activity, Pyrimidine, Stereochemistry, General Chemical Engineering, General Chemistry, Article, chemistry.chemical_compound, Chemistry, chemistry, In vivo, Epimer, Tumor growth, Swap (computer programming), QD1-999

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29a331e5552c24581a23a95aafbb773Test
https://doaj.org/article/8920fac56cd04386b0126955f672d5f2Test

المؤلفون: Aniello Federico, Apurva Gopisetty, Didier Surdez, Yasmine Iddir, Alexandra Saint-Charles, Justyna Wierzbinska, Andreas Schlicker, Richard Volckmann, Danny Zwijnenburg, Sara Colombetti, Olaf Heidenreich, Fatima Iradier, Heinrich Kovar, Jan-Henning Klusmann, Klaus-Michael Debatin, Simon Bomken, Christina Guttke, Maureen M. Hattersley, Frédéric Colland, Ashley Strougo, María José Guillén, Louis Chesler, Chris Jones, Maria Eugénia Marques da Costa, Katia Scotlandi, Massimo Moro, Beat Schäfer, Marco Wachtel, Johannes Gojo, Walter Berger, Ángel Montero Carcaboso, Dennis Gürgen, Jens Hoffmann, Emilie Indersie, Stefano Cairo, Julia Schueler, Nicole Huebener, Johannes H. Schulte, Jan J. Molenaar, Birgit Geoerger, David J. Shields, Hubert N. Caron, Gilles Vassal, Lou F. Stancato, Stefan M. Pfister, Natalie Jäger, Jan Koster, Marcel Kool, Gudrun Schleiermacher

المصدر: Cancer Research. 83:3571-3571

مصطلحات موضوعية: Cancer Research, Oncology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3c7d77b80bb6afd8e4ab4b8847a79869Test
https://doi.org/10.1158/1538-7445.am2023-3571Test

المؤلفون: Marcel Kool, Aniello Federico, Didier Surdez, Apurva Gopisetty, Elnaz Saberi-Ansari, Alexandra Saint-Charles, Yasmine Iddir, Joshua Waterfall, Justyna Wierzbinska, Andreas Schlicker, Jaydutt Bhalsankar, Norman Mack, Benjamin Schwalm, Anna-Lisa Böttcher, Martin Sill, Frank Westermann, David T W Jones, Richard Volckmann, Danny Zwijnenburg, Dennis Gürgen, Emilie Inderise, Johannes Schulte, Angelika Eggert, Jan J Molenaar, Olivier Delattre, Sara Colombetti, Olaf Heidenreich, Irmela Jeremias, Katia Scotlandi, Maria Cristina Manara, Johannes Gojo, Walter Berger, Fatima Iradier, Birgit Geoerger, Jenny Costa, Beat Schäfer, Marco Wachtel, Louis Chesler, Chris Jones, Heinrich Kovar, Ángel Montero Carcaboso, Jan-Henning Klusmann, Klaus-Michael Debatin, Simon Bomken, Christina Guttke, Petra Hamerlik, Maureen Hattersley, Michelle Garcia, Frédéric Colland, Ashley Strougo, Olaf Witt, Gilles Vassal, Hubert Caron, David J Shields, Lou F Stancato, Pablo M Aviles, Jens Hoffmann, Stefano Cairo, Julia Schueler, Natalie Jäger, Jan Koster, Gudrun Schleiermacher, Stefan M Pfister

المصدر: Neuro-Oncology. 24:i189-i189

مصطلحات موضوعية: Cancer Research, Oncology, Neurology (clinical)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0ae29eeb04131d53a4fafa97de70f2dfTest
https://doi.org/10.1093/neuonc/noac079.711Test

المؤلفون: Lan Zhang, Y. Wang, Jessica M. Salmon, Corina Ghiurau, Andrew H. Wei, David C.S. Huang, Donia M Moujalled, Audrey Claperon, Olivier Geneste, Sarah MacRaild, Ping Lan, Guillaume Lessene, David J. Segal, Ana Leticia Maragno, Frédéric Colland, Tse-Chieh Teh, Laurence Kraus-Berthier, Adrien Zichi, Francesca Rocchetti, Giovanna Pomilio, Andrew W. Roberts, Adam Ivey, Ing Soo Tiong, Erick Morris, Maïa Chanrion, Ensar Halilovic, Sewa Rijal

المصدر: Leukemia

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Myeloid, Mice, SCID, Mice, chemistry.chemical_compound, 0302 clinical medicine, Biomimetics, Mice, Inbred NOD, hemic and lymphatic diseases, Tumor Cells, Cultured, MCL1, Sulfonamides, Hematology, Myeloid leukemia, Leukemia, Myeloid, Acute, Leukemia, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Oncology, 030220 oncology & carcinogenesis, Drug Therapy, Combination, Female, medicine.medical_specialty, Antineoplastic Agents, Thiophenes, Article, Acute myeloid leukaemia, 03 medical and health sciences, Proto-Oncogene Proteins, Internal medicine, medicine, Animals, Humans, Venetoclax, business.industry, Translational research, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Xenograft Model Antitumor Assays, Peptide Fragments, Myeloid Cell Leukemia Sequence 1 Protein, Pyrimidines, 030104 developmental biology, chemistry, Cancer research, Bone marrow, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d5dc6690c6daf00a067441f8d8707eTest
https://doi.org/10.1038/s41375-018-0261-3Test

المؤلفون: Ana-Leticia Maragno, Attila Paczal, András Kotschy, Didier Demarles, James Edward Paul Davidson, Szlávik Zoltán, Allan E. Surgenor, Gaëtane Le Toumelin-Braizat, James Murray, Proszenyák Ágnes, Frédéric Colland, Gabor Radics, Szabolcs Sipos, Olivier Geneste, Balázs Bálint, Csékei Márton, Zoltán B. Szabó, Pawel Dokurno, Audrey Claperon, Anne-Marie Girard, Chen I-Jen, Alain Bruno, Gaëlle Lysiak-Auvity, Roderick E. Hubbard, Maïa Chanrion, Zoe Daniels

المصدر: Journal of medicinal chemistry. 63(22)

مصطلحات موضوعية: Myeloid, Cell, Antineoplastic Agents, Mice, SCID, 01 natural sciences, Protein Structure, Secondary, 03 medical and health sciences, chemistry.chemical_compound, Mice, Downregulation and upregulation, Drug Discovery, medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, Cancer, medicine.disease, HCT116 Cells, Small molecule, 0104 chemical sciences, Protein Structure, Tertiary, 010404 medicinal & biomolecular chemistry, Leukemia, medicine.anatomical_structure, Cell killing, chemistry, Cancer research, Molecular Medicine, Myeloid Cell Leukemia Sequence 1 Protein, Female, Lead compound, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4627a227ab78ca732e02dade24b1f98Test
https://pubmed.ncbi.nlm.nih.gov/33146521Test