المؤلفون: Newport, Emma, Pedrosa, Ana Rita, Lees, Delphine, Dukinfield, Matthew, Carter, Edward, Gomez-Escudero, Jesus, Casado, Pedro, Rajeeve, Vinothini, Reynolds, Louise E, R Cutillas, Pedro, Duffy, Stephen W, De Luxán Delgado, Beatriz, Hodivala-Dilke, Kairbaan

المصدر: Newport , E , Pedrosa , A R , Lees , D , Dukinfield , M , Carter , E , Gomez-Escudero , J , Casado , P , Rajeeve , V , Reynolds , L E , R Cutillas , P , Duffy , S W , De Luxán Delgado , B & Hodivala-Dilke , K 2022 , ' Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth ' , The Journal of Pathology , vol. 256 , no. 2 , pp. 235-247 . https://doi.org/10.1002/path.5833Test

مصطلحات موضوعية: Angiogenesis Inhibitors/pharmacology, Animals, Antibiotics, Antineoplastic/pharmacology, Apoptosis, Cell Line, Tumor, Cell Proliferation, Cytokines/metabolism, Doxorubicin/pharmacology, Drug Resistance, Neoplasm, Endothelial Cells/enzymology, Female, Focal Adhesion Kinase 1/antagonists & inhibitors, Humans, Male, Melanoma, Experimental/drug therapy, Mice, Inbred C57BL, Knockout, Neovascularization, Physiologic, Protein Kinase Inhibitors/pharmacology, Signal Transduction, Skin Neoplasms/drug therapy, Tumor Burden, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

العلاقة: https://researchportal.bath.ac.uk/en/publications/3e65ed66-8350-481b-a6e7-3a355113443bTest

الإتاحة: https://doi.org/10.1002/path.5833Test
https://researchportal.bath.ac.uk/en/publications/3e65ed66-8350-481b-a6e7-3a355113443bTest

المؤلفون: de Jonge, Maja J A, Steeghs, Neeltje, Lolkema, Martijn P, Hotte, Sebastien J, Hirte, Hal W, van der Biessen, Diane A J, Abdul Razak, Albiruni R, De Vos, Filip Y F L, Verheijen, Remy B, Schnell, David, Pronk, Linda C, Jansen, Monique, Siu, Lillian L

المساهمون: Externen Med. Onco, MS Medische Oncologie, Cancer

مصطلحات موضوعية: Adult, Aged, 80 and over, Female, Focal Adhesion Kinase 1/antagonists & inhibitors, Follow-Up Studies, Humans, Male, Maximum Tolerated Dose, Middle Aged, Neoplasm Metastasis, Neoplasms/drug therapy, Prognosis, Protein Kinase Inhibitors/pharmacokinetics, Tissue Distribution, Young Adult, Pharmacology (medical), Oncology, Cancer Research, Journal Article, Research Support, Non-U.S. Gov't, Clinical Trial, Phase I

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/392197Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/392197Test

المؤلفون: Verheijen, Remy B, van der Biessen, Diane A J, Hotte, Sebastien J, Siu, Lillian L, Spreafico, Anna, de Jonge, Maja J A, Pronk, Linda C, De Vos, Filip Y F L, Schnell, David, Hirte, Hal W, Steeghs, Neeltje, Lolkema, Martijn P

المساهمون: MS Medische Oncologie, Cancer, Externen Med. Onco

مصطلحات موضوعية: Administration, Oral, Adult, Aged, 80 and over, Area Under Curve, Capsules, Cross-Over Studies, Female, Focal Adhesion Kinase 1/antagonists & inhibitors, Food-Drug Interactions, Humans, Male, Maximum Tolerated Dose, Middle Aged, Neoplasm Metastasis, Neoplasms/drug therapy, Prognosis, Protein Kinase Inhibitors/pharmacokinetics, Tablets/administration & dosage, Therapeutic Equivalency, Tissue Distribution, Pharmacology (medical), Oncology, Cancer Research, Journal Article, Research Support, Non-U.S. Gov't, Clinical Trial, Phase I

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/390528Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/390528Test

المساهمون: Minjeong Jang, Ilkyoo Koh, Jae Eun Lee, Ju Yeon Lim, Jae-Ho Cheong, Pilnam Kim, Cheong, Jae Ho

مصطلحات موضوعية: Antigens, CD, Antimetabolites, Antineoplastic/pharmacology, Cadherins/metabolism, Cell Line, Tumor, Cell Proliferation, Drug Resistance, Neoplasm, Extracellular Matrix/metabolism, Fluorouracil/pharmacology, Focal Adhesion Kinase 1/antagonists & inhibitors, Focal Adhesion Kinase 1/metabolism, Humans, Integrin beta Chains/metabolism, Stomach Neoplasms/metabolism, Tumor Microenvironment, beta Catenin/metabolism

العلاقة: BIOMATERIALS SCIENCE; J03578; OAK-2018-10275; https://ir.ymlib.yonsei.ac.kr/handle/22282913/167169Test; https://pubs.rsc.org/en/Content/ArticleLanding/2018/BM/C8BM00843D#!divAbstractTest; T201805373; BIOMATERIALS SCIENCE, Vol.6(10) : 2704-2713, 2018

الإتاحة: https://doi.org/10.1039/c8bm00843dTest
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167169Test
https://pubs.rsc.org/en/Content/ArticleLanding/2018/BM/C8BM00843D#!divAbstractTest

المؤلفون: Lillian L. Siu, David Schnell, Remy B. Verheijen, Albiruni Ryan Abdul Razak, Martijn P. Lolkema, Linda C Pronk, Diane A.J. van der Biessen, Filip de Vos, Monique Jansen, Hal W. Hirte, Maja J.A. de Jonge, Sebastien J. Hotte, Neeltje Steeghs

المصدر: Targeted Oncology, 14(1), 43. Springer Paris
Targeted Oncology

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Peripheral edema, Gastroenterology, 0302 clinical medicine, Neoplasms, 80 and over, Tissue Distribution, Pharmacology (medical), Original Research Article, Neoplasm Metastasis, Non-U.S. Gov't, Aged, 80 and over, Proteinuria, Research Support, Non-U.S. Gov't, Protein Kinase Inhibitors/pharmacokinetics, Middle Aged, Prognosis, Clinical Trial, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Vomiting, Female, medicine.symptom, Focal Adhesion Kinase 1/antagonists & inhibitors, Adult, medicine.medical_specialty, Maximum Tolerated Dose, Nausea, Research Support, Clinical Trial, Phase I, 03 medical and health sciences, Young Adult, Phase I, Pharmacokinetics, Internal medicine, medicine, Journal Article, Humans, Adverse effect, Protein Kinase Inhibitors, Aged, business.industry, medicine.disease, Neoplasms/drug therapy, 030104 developmental biology, Focal Adhesion Kinase 1, Pharmacodynamics, business, Progressive disease, Follow-Up Studies

وصف الملف: text/plain; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7c1ccf4cf9b58aa00fc1c5eb11a31fTest
https://dspace.library.uu.nl/handle/1874/392197Test

المؤلفون: Neeltje Steeghs, Hal W. Hirte, Lillian L. Siu, Linda C Pronk, David Schnell, Sebastien J. Hotte, Martijn P. Lolkema, Maja J.A. de Jonge, Diane A.J. van der Biessen, Anna Spreafico, Filip de Vos, Remy B. Verheijen

المصدر: Targeted Oncology, 14(1), 67. Springer Paris
Targeted Oncology

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Analytical chemistry, Administration, Oral, Food-Drug Interactions, 0302 clinical medicine, Treatment compliance, Neoplasms, 80 and over, Medicine, Tissue Distribution, Pharmacology (medical), Original Research Article, Neoplasm Metastasis, Non-U.S. Gov't, Aged, 80 and over, Cross-Over Studies, Research Support, Non-U.S. Gov't, Protein Kinase Inhibitors/pharmacokinetics, Middle Aged, Prognosis, Clinical Trial, Oncology, 030220 oncology & carcinogenesis, Area Under Curve, Administration, Randomized Controlled Trial, Female, Open label, Focal Adhesion Kinase 1/antagonists & inhibitors, Tablets, Oral, Adult, Maximum Tolerated Dose, Cmax, Capsules, Bioequivalence, Research Support, Clinical Trial, Phase I, 03 medical and health sciences, Phase I, Pharmacokinetics, Journal Article, Humans, Protein Kinase Inhibitors, Aged, business.industry, Order (ring theory), Crossover study, Neoplasms/drug therapy, 030104 developmental biology, Therapeutic Equivalency, Focal Adhesion Kinase 1, Tablets/administration & dosage, Geometric mean, business

وصف الملف: image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ef3b440d343bd139872291c0d7410bTest
https://doi.org/10.1007/s11523-018-00618-0Test

المؤلفون: Schlosser, Anders, Pilecki, Bartosz, Hemstra, Line E, Kejling, Karin, Kristmannsdottir, Gudlaug B, Wulf-Johansson, Helle, Moeller, Jesper B, Füchtbauer, Ernst-Martin, Nielsen, Ole, Kirketerp-Møller, Katrine, Dubey, Lalit K, Hansen, Pernille B L, Stubbe, Jane, Wrede, Christoph, Hegermann, Jan, Ochs, Matthias, Rathkolb, Birgit, Schrewe, Anja, Bekeredjian, Raffi, Wolf, Eckhard, Gailus-Durner, Valérie, Fuchs, Helmut, de Angelis, Martin Hrabě, Lindholt, Jes S, Holmskov, Uffe, Sorensen, Grith L

المصدر: Schlosser , A , Pilecki , B , Hemstra , L E , Kejling , K , Kristmannsdottir , G B , Wulf-Johansson , H , Moeller , J B , Füchtbauer , E-M , Nielsen , O , Kirketerp-Møller , K , Dubey , L K , Hansen , P B L , Stubbe , J , Wrede , C , Hegermann , J , Ochs , M , Rathkolb , B , Schrewe , A , Bekeredjian , R , Wolf , E , Gailus-Durner , V , Fuchs , H , de Angelis , M H ....

مصطلحات موضوعية: MFAP4 protein, carotid stenosis, extracellular matrix proteins, hyperplasia, integrin alphaVbeta3, mouse, muscle, smooth, vascular, Chemotaxis, Leukocyte, Focal Adhesion Kinase 1/antagonists & inhibitors, Phosphorylation, Vascular Remodeling, Cell Movement/drug effects, Humans, Male, Neointima, Time Factors, Cell Proliferation/drug effects, Disease Models, Animal, Carotid Arteries/metabolism, Signal Transduction, Integrin alphaVbeta3/metabolism, Mice, Inbred C57BL, Cells, Cultured, Carotid Artery Diseases/genetics

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/972429ea-5786-4144-8770-53a5e547cf25Test

الإتاحة: https://doi.org/10.1161/ATVBAHA.115.306672Test
https://portal.findresearcher.sdu.dk/da/publications/972429ea-5786-4144-8770-53a5e547cf25Test

المؤلفون: Helle Wulf-Johansson, Bartosz Pilecki, Ernst-Martin Füchtbauer, Jane Stubbe, Line Ea Hemstra, Christoph Wrede, Martin Hrabé de Angelis, Pernille B. Lærkegaard Hansen, Anders Schlosser, Birgit Rathkolb, Gudlaug B Kristmannsdottir, Grith Lykke Sørensen, Karin Kejling, Jan Hegermann, Anja Schrewe, Jes S. Lindholt, Valerie Gailus-Durner, Raffi Bekeredjian, Lalit Kumar Dubey, Katrine Lindequist Kirketerp-Møller, Uffe Holmskov, Helmut Fuchs, Jesper B. Moeller, Matthias Ochs, Eckhard Wolf, Ole Haagen Nielsen

المصدر: Schlosser, A, Pilecki, B, Hemstra, L E, Kejling, K, Kristmannsdottir, G B, Wulf-Johansson, H, Moeller, J B, Füchtbauer, E-M, Nielsen, O, Kirketerp-Møller, K, Dubey, L K, Hansen, P B L, Stubbe, J, Wrede, C, Hegermann, J, Ochs, M, Rathkolb, B, Schrewe, A, Bekeredjian, R, Wolf, E, Gailus-Durner, V, Fuchs, H, de Angelis, M H, Lindholt, J S, Holmskov, U & Sorensen, G L 2016, ' MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, no. 1, pp. 122-133 . https://doi.org/10.1161/ATVBAHA.115.306672Test
Arterioscler. Thromb. Vasc. Biol. 36, 122-133 (2015)
Schlosser, A, Pilecki, B, Hemstra, L E, Kejling, K, Kristmannsdottir, G B, Wulf-Johansson, H, Moeller, J B, Füchtbauer, E M, Nielsen, O, Kirketerp-Møller, K, Dubey, L K, Hansen, P B L, Stubbe, J, Wrede, C, Hegermann, J, Ochs, M, Rathkolb, B, Schrewe, A, Bekeredjian, R, Wolf, E, Gailus-Durner, V, Fuchs, H, De Angelis, M H, Lindholt, J S, Holmskov, U & Sorensen, G L 2016, ' MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 36, no. 1, pp. 122-133 . https://doi.org/10.1161/ATVBAHA.115.306672Test

مصطلحات موضوعية: Carotid Artery Diseases, 0301 basic medicine, Male, Carrier Proteins/genetics, Vascular smooth muscle, Time Factors, Monocyte chemotaxis, muscle, Cell Movement/drug effects, Apoptosis, Ligands, Monocytes, Muscle, Smooth, Vascular, extracellular matrix proteins, Cell Proliferation/drug effects, vascular, Cell Movement, Monocytes/metabolism, Phosphorylation, Cells, Cultured, Neointimal hyperplasia, Mice, Knockout, Extracellular Matrix Proteins, Integrin alphaVbeta3, Mice, Inbred BALB C, biology, Mfap4 Protein, Mouse, Carotid Stenosis, Hyperplasia, Cell biology, Chemotaxis, Leukocyte, Carotid Arteries, Phenotype, carotid stenosis, Extracellular Matrix Proteins/deficiency, Cardiology and Cardiovascular Medicine, Focal Adhesion Kinase 1/antagonists & inhibitors, Myocytes, Smooth Muscle/drug effects, smooth, Signal Transduction, Neointima, Genotype, Myocytes, Smooth Muscle, Integrin, MFAP4 protein, integrin alphaVbeta3, Vascular Remodeling, Integrin alphaVbeta3/metabolism, Focal adhesion, 03 medical and health sciences, Carotid Arteries/metabolism, medicine, Humans, Animals, Protein Kinase Inhibitors, mouse, Cell Proliferation, Glycoproteins, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Glycoproteins/deficiency, Focal Adhesion Kinase 1, Protein Kinase Inhibitors/pharmacology, Immunology, biology.protein, Carotid Artery Diseases/genetics, Muscle, Smooth, Vascular/drug effects, Carrier Proteins, Ex vivo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05749c460e20b174816b6b1d5c31b7beTest
https://portal.findresearcher.sdu.dk/da/publications/972429ea-5786-4144-8770-53a5e547cf25Test