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1دورية أكاديمية
المؤلفون: Koh, Kyung Duk, Bonser, Luke R, Eckalbar, Walter L, Yizhar-Barnea, Ofer, Shen, Jiangshan, Zeng, Xiaoning, Hargett, Kirsten L, Sun, Dingyuan I, Zlock, Lorna T, Finkbeiner, Walter E, Ahituv, Nadav, Erle, David J
المصدر: Cell Genomics. 3(1)
مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Lung, Biotechnology, Asthma, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Respiratory, Good Health and Well Being, CRISPRi, HBEC, IL-13, SPDEF, asthma, cell-specific, enhancer
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7cs6d3x1Test
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2دورية أكاديمية
المؤلفون: Bonser, Luke R, Eckalbar, Walter L, Rodriguez, Lauren, Shen, Jiangshan, Koh, Kyung Duk, Ghias, Khadija, Zlock, Lorna T, Christenson, Stephanie, Woodruff, Prescott G, Finkbeiner, Walter E, Erle, David J
المصدر: American Journal of Respiratory Cell and Molecular Biology. 66(4)
مصطلحات موضوعية: Medical Microbiology, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Biological Sciences, Prevention, Pneumonia & Influenza, Lung, Biotechnology, Genetics, Infectious Diseases, Asthma, Emerging Infectious Diseases, Pneumonia, Aetiology, 2.1 Biological and endogenous factors, Infection, Respiratory, Good Health and Well Being, COVID-19, Cells, Cultured, Epithelial Cells, Epithelium, Humans, Interleukin-13, SARS-CoV-2, asthma, IL-13, airway epithelium, Cardiorespiratory Medicine and Haematology, Respiratory System, Biochemistry and cell biology, Cardiovascular medicine and haematology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7rw881r4Test
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3دورية أكاديمية
المؤلفون: Phuan, Puay-Wah, Haggie, Peter M, Tan, Joseph A, Rivera, Amber A, Finkbeiner, Walter E, Nielson, Dennis W, Thomas, Merlin M, Janahi, Ibrahim A, Verkman, Alan S
المصدر: Journal of Cystic Fibrosis. 20(3)
مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cystic Fibrosis, Lung, Clinical Research, Genetics, Rare Diseases, Aetiology, 2.1 Biological and endogenous factors, Congenital, Aminophenols, Aminopyridines, Benzodioxoles, Cells, Cultured, Chloride Channel Agonists, Cystic Fibrosis Transmembrane Conductance Regulator, Humans, Indoles, Mutant Proteins, Mutation, Missense, Pyrazoles, Pyridines, Pyrrolidines, Quinolones, Cystic fibrosis, I1234V, C.3700A > G, CFTR modulators, Co-potentiators, N-of-1 clinical trials, C.3700A>G, Clinical Sciences, Respiratory System, Clinical sciences
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/77x1z7kqTest
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4دورية أكاديمية
المؤلفون: Siddiqui, Sana, Johansson, Kristina, Joo, Alex, Bonser, Luke R, Koh, Kyung Duk, Le Tonqueze, Olivier, Bolourchi, Samaneh, Bautista, Rodriel A, Zlock, Lorna, Roth, Theodore L, Marson, Alexander, Bhakta, Nirav R, Ansel, K Mark, Finkbeiner, Walter E, Erle, David J, Woodruff, Prescott G
المصدر: JCI insight. 6(5)
مصطلحات موضوعية: Asthma, Noncoding RNAs, Pulmonology, Th2 response, Clinical Research, Genetics, Biotechnology, Lung, 2.1 Biological and endogenous factors, Respiratory
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/0r35v307Test
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5دورية أكاديمية
المؤلفون: Bonser, Luke R, Koh, Kyung Duk, Johansson, Kristina, Choksi, Semil P, Cheng, Dan, Liu, Leqian, Sun, Dingyuan I, Zlock, Lorna T, Eckalbar, Walter L, Finkbeiner, Walter E, Erle, David J
المصدر: American Journal of Respiratory Cell and Molecular Biology. 64(3)
مصطلحات موضوعية: Biotechnology, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Genetics, Aetiology, 2.1 Biological and endogenous factors, Antibodies, Biomarkers, Cell Separation, Epithelial Cells, Flow Cytometry, Humans, Respiratory System, airway epithelium, single-cell RNA sequencing, flow cytometry, Cardiorespiratory Medicine and Haematology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/3mn7w4npTest
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6دورية أكاديمية
المؤلفون: Koh, Kyung Duk, Siddiqui, Sana, Cheng, Dan, Bonser, Luke R, Sun, Dingyuan I, Zlock, Lorna T, Finkbeiner, Walter E, Woodruff, Prescott G, Erle, David J
المصدر: American Journal of Respiratory Cell and Molecular Biology. 62(3)
مصطلحات موضوعية: Medical Biotechnology, Biological Sciences, Biomedical and Clinical Sciences, Genetics, Asthma, Biotechnology, Lung, Aetiology, 2.1 Biological and endogenous factors, Respiratory, Good Health and Well Being, Bronchi, CRISPR-Cas Systems, Cells, Cultured, Down-Regulation, Epithelial Cells, Gene Expression Regulation, Gene Targeting, Goblet Cells, Humans, Interleukin-13, Metaplasia, Mucin 5AC, Mucociliary Clearance, Primary Cell Culture, Proto-Oncogene Proteins c-ets, RNA, Guide, Kinetoplastida, Ribonucleoproteins, Transcriptome, CRISPR, human bronchial epithelial cells, SPDEF, goblet, MUC5AC, Cardiorespiratory Medicine and Haematology, Respiratory System, Biochemistry and cell biology, Cardiovascular medicine and haematology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/4189337cTest
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7دورية أكاديمية
المؤلفون: Park, Jeffrey KiHyun, Shrivastava, Anura, Zhang, Chengkang, Pollok, Brian A, Finkbeiner, Walter E, Gibb, Elizabeth R, Ly, Ngoc P, Illek, Beate
مصطلحات موضوعية: Rare Diseases, Cystic Fibrosis, Orphan Drug, Lung, Good Health and Well Being, Cystic fibrosis, mutation-specific CFTR function analysis, CFTRdele2, 3(21kb) (c, 54-5940_270+10250del21 kb, p, Ser18ArgfsX16), c, 850dupA (977insA, Met284Asnfs), R334W (c, 1000C>T, Arg334Trp), 406-1G->A (c, 274-1G>A), R117H-7T (c, 350G>A, Arg117His), F508del (c, 1521_1523delCTT, Phe508del), 3(21kb) (c.54-5940_270+10250del21 kb, 406-1G->A, F508del (c.1521_1523delCTT, R117H-7T (c.350G>A, R334W (c.1000C>T, c.850dupA (977insA, p.Arg117His), p.Arg334Trp), p.Met284Asnfs), p.Phe508del), p.Ser18ArgfsX16), Paediatrics and Reproductive Medicine, Other Medical and Health Sciences
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/2n72q3hkTest
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8دورية أكاديمية
المؤلفون: Phuan, Puay-Wah, Tan, Joseph-Anthony, Rivera, Amber A, Zlock, Lorna, Nielson, Dennis W, Finkbeiner, Walter E, Haggie, Peter M, Verkman, Alan S
المصدر: Scientific reports. 9(1)
مصطلحات موضوعية: Humans, Cystic Fibrosis, Piperidines, Pyrazoles, Cystic Fibrosis Transmembrane Conductance Regulator, Structure-Activity Relationship, Drug Synergism, Mutation, Drug Discovery, High-Throughput Screening Assays
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/20t0z843Test
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9دورية أكاديمية
المؤلفون: Phuan, Puay-Wah, Veit, Guido, Tan, Joseph-Anthony, Roldan, Ariel, Finkbeiner, Walter E, Haggie, Peter M, Lukacs, Gergely L, Verkman, Alan S
المصدر: SLAS DISCOVERY. 23(8)
مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Cystic Fibrosis, Rare Diseases, Lung, Genetics, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Animals, Cell Line, Cell Membrane, Cystic Fibrosis Transmembrane Conductance Regulator, Drug Discovery, Gene Expression Regulation, Genes, Reporter, High-Throughput Screening Assays, Humans, Molecular Structure, Protein Interaction Domains and Motifs, Structure-Activity Relationship, cystic fibrosis, CFTR, high-throughput screen, potentiator, Biochemistry and Cell Biology, Medicinal & Biomolecular Chemistry, Biochemistry and cell biology, Medical biochemistry and metabolomics, Medical biotechnology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7051n7ddTest
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10دورية أكاديمية
المؤلفون: Phuan, Puay-Wah, Son, Jung-Ho, Tan, Joseph-Anthony, Li, Clarabella, Musante, Ilaria, Zlock, Lorna, Nielson, Dennis W, Finkbeiner, Walter E, Kurth, Mark J, Galietta, Luis J, Haggie, Peter M, Verkman, Alan S
المصدر: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 17(5)
مصطلحات موضوعية: Cells, Cultured, Cell Line, Animals, Humans, Cystic Fibrosis, Sulfonamides, Aminophenols, Quinolones, Cystic Fibrosis Transmembrane Conductance Regulator, Ion Channel Gating, Structure-Activity Relationship, Drug Synergism, Mutation, Mutant Proteins, CFTR, Cystic fibrosis, High-throughput screen, N1303K, Potentiator, Rare Diseases, Lung, Congenital, Clinical Sciences, Respiratory System
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/2v57q576Test