المؤلفون: Wolfe, Cameron R, Tomashek, Kay M, Patterson, Thomas F, Gomez, Carlos A, Marconi, Vincent C, Jain, Mamta K, Yang, Otto O, Paules, Catharine I, Palacios, Guillermo M Ruiz, Grossberg, Robert, Harkins, Michelle S, Mularski, Richard A, Erdmann, Nathaniel, Sandkovsky, Uriel, Almasri, Eyad, Pineda, Justino Regalado, Dretler, Alexandra W, de Castilla, Diego Lopez, Branche, Angela R, Park, Pauline K, Mehta, Aneesh K, Short, William R, McLellan, Susan LF, Kline, Susan, Iovine, Nicole M, El Sahly, Hana M, Doernberg, Sarah B, Oh, Myoung-Don, Huprikar, Nikhil, Hohmann, Elizabeth, Kelley, Colleen F, Holodniy, Mark, Kim, Eu Suk, Sweeney, Daniel A, Finberg, Robert W, Grimes, Kevin A, Maves, Ryan C, Ko, Emily R, Engemann, John J, Taylor, Barbara S, Ponce, Philip O, Larson, LuAnn, Melendez, Dante Paolo, Seibert, Allan M, Rouphael, Nadine G, Strebe, Joslyn, Clark, Jesse L, Julian, Kathleen G, de Leon, Alfredo Ponce, Cardoso, Anabela, de Bono, Stephanie, Atmar, Robert L, Ganesan, Anuradha, Ferreira, Jennifer L, Green, Michelle, Makowski, Mat, Bonnett, Tyler, Beresnev, Tatiana, Ghazaryan, Varduhi, Dempsey, Walla, Nayak, Seema U, Dodd, Lori E, Beigel, John H, Kalil, Andre C, ACTT-4 Study Group

المصدر: The Lancet. Respiratory medicine. 10(9)

مصطلحات موضوعية: ACTT-4 Study Group, Humans, Oxygen, Sulfonamides, Azetidines, Pyrazoles, Purines, Dexamethasone, Treatment Outcome, Double-Blind Method, Adolescent, Adult, Middle Aged, Female, Male, SARS-CoV-2, COVID-19 Drug Treatment, Clinical Trials and Supportive Activities, Lung, Clinical Research, Prevention, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Good Health and Well Being, Clinical Sciences, Public Health and Health Services, Other Medical and Health Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/80g6394wTest

المؤلفون: Lim, Sun-Young, Guo, Zhiru, Liu, Ping, McKay, Lindsay G A, Storm, Nadia, Griffiths, Anthony, Qu, Ming Da, Finberg, Robert W, Somasundaran, Mohan, Wang, Jennifer P

المساهمون: Biochemistry and Molecular Biotechnology, Medicine, Morningside Graduate School of Biomedical Sciences, Sun-Young Lim

المصدر: COVID ; 2 ; 11 ; 1551 ; 1563 ; United States ; Switzerland

مصطلحات موضوعية: ACE2-A549 cells, COVID-19, SARS-CoV-2, amantadine, hamster, rimantadine

العلاقة: COVID; https://doi.org/10.3390/covid2110111Test; Lim SY, Guo Z, Liu P, McKay LGA, Storm N, Griffiths A, Qu MD, Finberg RW, Somasundaran M, Wang JP. Anti-SARS-CoV-2 Activity of Adamantanes In Vitro and in Animal Models of Infection. COVID. 2022 Nov;2(11):1551-1563. doi:10.3390/covid2110111. Epub 2022 Oct 28. PMID: 37274537; PMCID: PMC10238102.; http://hdl.handle.net/20.500.14038/53146Test

الإتاحة: https://doi.org/10.3390/covid2110111Test
https://doi.org/20.500.14038/53146Test
https://hdl.handle.net/20.500.14038/53146Test

المؤلفون: Kalil, Andre C, Patterson, Thomas F, Mehta, Aneesh K, Tomashek, Kay M, Wolfe, Cameron R, Ghazaryan, Varduhi, Marconi, Vincent C, Ruiz-Palacios, Guillermo M, Hsieh, Lanny, Kline, Susan, Tapson, Victor, Iovine, Nicole M, Jain, Mamta K, Sweeney, Daniel A, El Sahly, Hana M, Branche, Angela R, Regalado Pineda, Justino, Lye, David C, Sandkovsky, Uriel, Luetkemeyer, Anne F, Cohen, Stuart H, Finberg, Robert W, Jackson, Patrick EH, Taiwo, Babafemi, Paules, Catharine I, Arguinchona, Henry, Erdmann, Nathaniel, Ahuja, Neera, Frank, Maria, Oh, Myoung-Don, Kim, Eu-Suk, Tan, Seow Y, Mularski, Richard A, Nielsen, Henrik, Ponce, Philip O, Taylor, Barbara S, Larson, LuAnn, Rouphael, Nadine G, Saklawi, Youssef, Cantos, Valeria D, Ko, Emily R, Engemann, John J, Amin, Alpesh N, Watanabe, Miki, Billings, Joanne, Elie, Marie-Carmelle, Davey, Richard T, Burgess, Timothy H, Ferreira, Jennifer, Green, Michelle, Makowski, Mat, Cardoso, Anabela, de Bono, Stephanie, Bonnett, Tyler, Proschan, Michael, Deye, Gregory A, Dempsey, Walla, Nayak, Seema U, Dodd, Lori E, Beigel, John H

المصدر: New England Journal of Medicine. 384(9)

مصطلحات موضوعية: Rehabilitation, Clinical Trials and Supportive Activities, Lung, Clinical Research, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Good Health and Well Being, Adenosine Monophosphate, Adult, Aged, Alanine, Antiviral Agents, Azetidines, COVID-19, Double-Blind Method, Drug Therapy, Combination, Female, Hospital Mortality, Hospitalization, Humans, Janus Kinase Inhibitors, Male, Middle Aged, Oxygen Inhalation Therapy, Purines, Pyrazoles, Respiration, Artificial, Sulfonamides, Treatment Outcome, COVID-19 Drug Treatment, ACTT-2 Study Group Members, Medical and Health Sciences, General & Internal Medicine

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4wj737q4Test

المؤلفون: Beigel, John H, Tomashek, Kay M, Dodd, Lori E, Mehta, Aneesh K, Zingman, Barry S, Kalil, Andre C, Hohmann, Elizabeth, Chu, Helen Y, Luetkemeyer, Annie, Kline, Susan, Lopez de Castilla, Diego, Finberg, Robert W, Dierberg, Kerry, Tapson, Victor, Hsieh, Lanny, Patterson, Thomas F, Paredes, Roger, Sweeney, Daniel A, Short, William R, Touloumi, Giota, Lye, David Chien, Ohmagari, Norio, Oh, Myoung-Don, Ruiz-Palacios, Guillermo M, Benfield, Thomas, Fätkenheuer, Gerd, Kortepeter, Mark G, Atmar, Robert L, Creech, C Buddy, Lundgren, Jens, Babiker, Abdel G, Pett, Sarah, Neaton, James D, Burgess, Timothy H, Bonnett, Tyler, Green, Michelle, Makowski, Mat, Osinusi, Anu, Nayak, Seema, Lane, H Clifford

المصدر: New England Journal of Medicine. 383(19)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Infectious Diseases, Clinical Trials and Supportive Activities, Clinical Research, Rehabilitation, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Infection, Good Health and Well Being, Adenosine Monophosphate, Administration, Intravenous, Adult, Aged, Alanine, Antiviral Agents, Betacoronavirus, COVID-19, Coronavirus Infections, Double-Blind Method, Extracorporeal Membrane Oxygenation, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Oxygen Inhalation Therapy, Pandemics, Pneumonia, Viral, Respiration, Artificial, SARS-CoV-2, Time Factors, Young Adult, COVID-19 Drug Treatment, ACTT-1 Study Group Members, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6t2835gjTest

المؤلفون: Becerra-Artiles, Aniuska, Calvo-Calle, J Mauricio, Co, Mary Dawn, Nanaware, Padma P, Cruz, John, Weaver, Grant, Lu, Liying, Forconi, Catherine S, Finberg, Robert W, Moormann, Ann M, Stern, Lawrence J

المساهمون: Biochemistry and Molecular Biotechnology, Medicine, Morningside Graduate School of Biomedical Sciences, Pathology

المصدر: Cell reports ; 39 ; 11 ; 110952 ; United States

مصطلحات موضوعية: CD4 T cells, CP: Immunology, CP: Microbiology, T cell receptor repertoire, heterologous immunity, major histocompatibility complex, seasonal coronavirus, spike fusion peptide proximal region

العلاقة: This article is based on a previously available preprint in bioRxiv, https://doi.org/10.1101/2022.01.20.477107Test.; Cell Reports; https://doi.org/10.1016/j.celrep.2022.110952Test; Becerra-Artiles A, Calvo-Calle JM, Co MD, Nanaware PP, Cruz J, Weaver GC, Lu L, Forconi C, Finberg RW, Moormann AM, Stern LJ. Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles. Cell Rep. 2022 Jun 14;39(11):110952. doi:10.1016/j.celrep.2022.110952. Epub 2022 May 27. PMID: 35675811; PMCID: PMC9135679.; http://hdl.handle.net/20.500.14038/51529Test

الإتاحة: https://doi.org/10.1016/j.celrep.2022.110952Test
https://doi.org/20.500.14038/51529Test
https://doi.org/10.1101/2022.01.20.477107Test
https://hdl.handle.net/20.500.14038/51529Test

المؤلفون: Hariharan, Vignesh N, Shin, Minwook, Chang, Ching-Wen, O'Reilly, Daniel, Biscans, Annabelle, Yamada, Ken, Guo, Zhiru, Somasundaran, Mohan, Tang, Qi, Monopoli, Kathryn, Krishnamurthy, Pranathi Meda, Devi, Gitali, McHugh, Nicholas, Cooper, David A, Echeverria, Dimas, Cruz, John, Chan, Io Long, Liu, Ping, Lim, Sun-Young, McConnell, Jill, Singh, Satya Prakash, Hildebrand, Samuel, Sousa, Jacquelyn, Davis, Sarah M, Kennedy, Zachary, Ferguson, Chantal, Godinho, Bruno M D C, Thillier, Yann, Caiazzi, Jillian, Ly, Socheata, Muhuri, Manish, Kelly, Karen, Humphries, Fiachra, Cousineau, Alyssa, Parsi, Krishna Mohan, Li, Qi, Wang, Yang, Maehr, René, Gao, Guangping, Korkin, Dmitry, McDougall, William M, Finberg, Robert W, Fitzgerald, Katherine A, Wang, Jennifer P, Watts, Jonathan K, Khvorova, Anastasia

المساهمون: Biochemistry and Molecular Biotechnology, Diabetes Center of Excellence, Horae Gene Therapy Center, Li Weibo Institute for Rare Diseases Research, MassBiologics, Medicine, Microbiology and Physiological Systems, Morningside Graduate School of Biomedical Sciences, Pathology, Program in Innate Immunity, Program in Molecular Medicine, RNA Therapeutics Institute, David A Cooper, Samuel Hildebrand, Sarah M Davis

المصدر: Proceedings of the National Academy of Sciences of the United States of America ; 120 ; 11 ; e2219523120 ; United States

مصطلحات موضوعية: SARS-COV-2, antisense oligos, lung, mouse model, small interfering RNAs

العلاقة: Proceedings of the National Academy of Sciences; https://doi.org/10.1073/pnas.2219523120Test; Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219523120. doi:10.1073/pnas.2219523120. Epub 2023 Mar 9. PMID: 36893269.; http://hdl.handle.net/20.500.14038/51911Test; Proceedings of the National Academy of Sciences of the United States of America

الإتاحة: https://doi.org/10.1073/pnas.2219523120Test
https://doi.org/20.500.14038/51911Test
https://hdl.handle.net/20.500.14038/51911Test

المؤلفون: Chang, Ching-Wen, Parsi, Krishna Mohan, Somasundaran, Mohan, Vanderleeden, Emma, Liu, Ping, Cruz, John, Cousineau, Alyssa, Finberg, Robert W, Kurt-Jones, Evelyn A

المساهمون: Biochemistry and Molecular Biotechnology, Diabetes Center of Excellence, Medicine, Pathology, Program in Molecular Medicine

المصدر: Viruses ; 14 ; 7 ; Switzerland

مصطلحات موضوعية: A549, ACE2, EIDD-1931, SARS-CoV-2, TMPRSS2, delta and omicron variants, nirmatrelvir, remdesivir

العلاقة: Viruses; https://doi.org/10.3390/v14071369Test; Chang CW, Parsi KM, Somasundaran M, Vanderleeden E, Liu P, Cruz J, Cousineau A, Finberg RW, Kurt-Jones EA. A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants. Viruses. 2022 Jun 23;14(7):1369. doi:10.3390/v14071369. PMID: 35891350; PMCID: PMC9318744.; http://hdl.handle.net/20.500.14038/52720Test

الإتاحة: https://doi.org/10.3390/v14071369Test
https://doi.org/20.500.14038/52720Test
https://hdl.handle.net/20.500.14038/52720Test

المؤلفون: Bazzone, Lindsey E., Zhu, Junji, King, Michael, Liu, GuanQun, Guo, Zhiru, MacKay, Christopher R., Kyawe, Pyae P., Qaisar, Natasha, Rojas-Quintero, Joselyn, Owen, Caroline A., Brass, Abraham L., McDougall, William, Baer, Christina E., Cashman, Timothy, Trivedi, Chinmay M., Gack, Michaela U., Finberg, Robert W., Kurt-Jones, Evelyn A.

المصدر: Nature Communications; 5/16/2024, Vol. 15 Issue 1, p1-14, 14p

مصطلحات موضوعية: TYPE I interferons, VIRUS diseases, NATURAL immunity, MITOCHONDRIAL proteins, MYOCARDITIS

المؤلفون: Wolfe, Cameron R., Tomashek, Kay M., Patterson, Thomas F., Gomez, Carlos A., Marconi, Vincent C., Jain, Mamta K., Yang, Otto O., Paules, Catharine, I, Ruiz Palacios, Guillermo M., Grossberg, Robert, Harkins, Michelle S., Mularski, Richard A., Erdmann, Nathaniel, Sandkovsky, Uriel, Almasri, Eyad, Regalado Pineda, Justino, Dretler, Alexandra W., de Castilla, Diego Lopez, Branche, Angela R., Park, Pauline K., Mehta, Aneesh K., Short, William R., McLellan, Susan L. F., Kline, Susan, Iovine, Nicole M., El Sahly, Hana M., Doernberg, Sarah B., Oh, Myoung-don, Huprikar, Nikhil, Hohmann, Elizabeth, Kelley, Colleen F., Holodniy, Mark, Kim, Eu Suk, Sweeney, Daniel A., Finberg, Robert W., Grimes, Kevin A., Maves, Ryan C., Ko, Emily R., Engemann, John J., Taylor, Barbara S., Ponce, Philip O., Larson, LuAnn, Melendez, Dante Paolo, Seibert, Allan M., Rouphael, Nadine G., Strebe, Joslyn, Clark, Jesse L., Julian, Kathleen G., Ponce de Leon, Alfredo, Cardoso, Anabela, de Bono, Stephanie, Atmar, Robert L., Ganesan, Anuradha, Ferreira, Jennifer L., Green, Michelle, Makowski, Mat, Bonnett, Tyler, Beresnev, Tatiana, Ghazaryan, Varduhi, Dempsey, Walla, Nayak, Seema U., Dodd, Lori E., Beigel, John H., Kalil, Andre C.

المساهمون: Oh, Myoung-don, Kim, Eu Suk

العلاقة: The Lancet Respiratory Medicine, Vol.10 No.9, pp.888-899; https://hdl.handle.net/10371/188916Test; 000870059100025; 2-s2.0-85131668385; 174934

الإتاحة: https://doi.org/10.1016/S2213-2600Test(22)00088-1
https://hdl.handle.net/10371/188916Test

المؤلفون: Ogembo, Javier Gordon, Muraswki, Matthew R., Cullen, Lori McGinnes, Parcharidou, Agapi, Sutiwisesak, Rujapak, Tison, Timelia, Avendano, Juan, Agnani, Deep, Finberg, Robert W., Morrison, Trudy G., Fingeroth, Joyce D.

المساهمون: Program in Immunology and Microbiology, Department of Microbiology and Physiological Systems, Department of Medicine, Division of Infectious Diseases and Immunology

المصدر: Journal of translational medicine ; 13 ; 1 ; 50

مصطلحات موضوعية: Immunology of Infectious Disease, Immunoprophylaxis and Therapy, Translational Medical Research, Virology, Virus Diseases, Viruses

العلاقة: Link to Article in PubMed; J Transl Med. 2015 Feb 6;13(1):50. doi:10.1186/s12967-015-0415-2. Link to article on publisher's site; 1479-5876 (Linking); http://hdl.handle.net/20.500.14038/39715Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=3516&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/2513Test; 7161386; oapubs/2513

الإتاحة: https://doi.org/10.1186/s12967-015-0415-2Test
https://doi.org/20.500.14038/39715Test
https://hdl.handle.net/20.500.14038/39715Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=3516&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/2513Test