التفاصيل البيبلوغرافية
| العنوان: |
Paediatric nephrology |
| المؤلفون: |
Gulati, Ashima, Math, A., Sreeniwas, V., Hari, P., Bagga, A., Miao, Jing, Fan, Qingfeng, Zhang, Han, Chen, Lihong, Zhu, Sen, Li, Jing, Wang, Suxia, Cui, Qinghua, Guan, Youfei, Ding, Jie, Szczesniak, Przemyslaw, Czarniak, Piotr, Krol, Ewa, Krawczyk, Michal, Zdrojewski, Tomasz, Rutkowski, Boleslaw, Hammad, Ayman Mohammad, Zaghloul, Mohammad Hosam El Deen, Safouh, Hesham, Eslayyed, Rokayya, Elkaraksy, Hanaa, Elshabrawi, Mortada, Guan, Na, Fan, Qing Feng, Duan, He Jun, Shao, Bing, Waters, A., Quinlan, C., Bockenhauer, D., Van't Hoff, W., Prikhodina, Larisa, Dlin, Vladimir, Ignatova, Maya, Mehls, Otto, Lindberg, Anders, de Ridder, Maria, Nissel, Richard, Haffner, Dieter, Hokken-Koelega, Anita, Ranke, Michael B., Turolo, Stefano, Tirelli, Amedea Silvia, Belingheri, Mirco, Ferraresso, Mariano, Bernardinelli, Luisa, Ghio, Luciana, Edefonti, Alberto, Zhang, Shao-Ling, Chenier, Isabelle, Chen, Yun-Wen, Chan, John S.D., Ingelfinger, Julie R., Gulati, Sanjeev, Sharma, Rajkumar, Kumar, Alok, Agrawal, Suraksha, Tripathi, Gaurav, Jafar, Tabrez, Mandal, Kausik, Baburajan, Vinod P., Kher, Vijay, Musial, Kinga, Makulska, Irena, Zwolinska, Danuta, El-Husseini, Amr, Hassan, Rashad, Sobh, Mohamed, Ghoneim, Mohamed, Hoseini, Rozita, Otukesh, Hasan, Sharifi Aghdas, Farzaneh, Park, Hye Won, Choi, Hyoungso, Kim, Namkeun, Oh, Doyeon, Fereshteh Nejad, Mahamd, Rahimzadeh, Nahid, Chua, Annabelle, Symons, Jordan, Somers, Michael, Baum, Michelle, Brophy, Patrick, Blowey, Douglas, Fortenberry, James, Flores, Francisco, Benfield, Mark, Alexander, Steven, Askenazi, David, Hackbarth, Richard, Bunchman, Timothy, Goldstein, Stuart, Fomina, Svetlana, Bagdasarova, Ingrieta, Obukhova, Varvara, Turpitko, Olga, Seeherunvong, Wacharee, Abitbol, Carolyn, Chandar, Jayanthi, Zilleruelo, Gaston, Freundlich, Michael, Ziolkowska, Helena, Roszkowska-Blaim, Maria, Gorska, Elzbieta, Stelmaszczyk-Emmel, Anna, Grenda, Ryszard, Pietrzyk, Jacek A., Mader-Wolynska, Izabella, Zachwieja, Jacek, Balat, Ayse, Oguzkan Balci, Sibel, Buyukcelik, Mithat, Gogebakan, Bulent, Col Araz, Nilgun, Ciftci, Mustafa, Gok, Faysal, Kainer, Gad, Armstrong, Jessica, Laing, David, Wilkes, Fiona, Aitken, Maggie, Karimi, Abdollah, Ghafari, Alireza, Sharifian, Mostafa, Asgarian, Fahimeh, Dalirani, Reza, Tavares, Marcelo, Penido, Maria Goretti, Peloi, Hilton, Saridakis, Halha, Nimtz, Alessandra, Semerci, Nevin, Sonmez, Ferah, Girisgen, Ilknur, Calik, Arzu, Eyigor, Mete, Resontoc, Lourdes Paula, Collado, Almira, Fajardo, Pamela, Trivedi, Hargovind, Gera, Dinesh, Vanikar, Aruna, Falodia, Jitendra, Kanodia, Kamal, Shah, Pankaj, Kim, Ji Hong, Lee, Jae Seung, Jeong, Hyeon Joo, Kim, Pyung Kil, Michelson, Kenneth, Sise, Meghan, Huynh, Trang, Parravicini, Elvira, Lorenz, John, Bateman, David, Nemerofsky, Sheri, Marion, Stephanie, Barasch, Jonathan, Benz, Kerstin, Dittrich, Katalin, Campean, Valentina, Dötsch, Jörg, Amann, Kerstin, Yildiz, Bilal, Kural, Nurdan, Poyraz, Hulya, Jobs, Katarzyna, Jung, Anna, Jurkiewicz, Beata, Bochniewska, Violetta, Kalin, Katarzyna, Zieniuk, Emilia, Gallieni, Maurizio, Aiello, Angela, Brahmochary Mandal, Sujit, Giussani, Marco, Antolini, Laura, Cusi, Daniele, Stella, Andrea, Genovesi, Simonetta, Basic, Jelena, Golubovic, Emilija, Miljkovic, Predrag, Cvetkovic, Tatjana, Milosevic, Vuk, Davin, Jean-Claude, Bouts, Antonia, Groothoff, Jaap, Strain, Lisa, Goodship, Tim, Khazaei, Mahmood Reza, Omid, Fatemeh, Aghel, Azadeh, Bohlke, Maristela, Dullius, Fernanda, Menezes, Juliana, Cunha, Tiago, Boemer, Hayslan, Menezes, Adriana, Caruso, Paulo, Barcellos, Franklin, Shin, Jae Il, Kim, Myung Joon, Polak-Jonkisz, Dorota, Laszki-Szczachor, Krystyna, Sobieszczanska, Malgorzata, Rusiecki, Leszek, Lavrenchuk, Olga, Mihal, Lyudmila, Bagdasarova, Ingretta, Szczepanska, Maria, Sedek, Lukasz, Bulsa, Joanna, Szprynger, Krystyna, Mazur, Bogdan, Matyl, Aleksander, Szczepanski, Tomasz, Madani, Abbas, Esfahani, Seyed Taher, Moghtaderi, Mastaneh, Pereira, Regina Maria, Gomes, Romina Aparecida, Pereira, AndréBarreto, Oliveira, Eduardo Araújo, Simoes e Silva, Ana Cristina, Esezobor, Christopher, Iroha, Edna, Onifade, Elizabeth, Baskin, Esra, Bayrakci, Umut Selda, Yazar, Baris, Gulleroglu, Kaan, Cengiz, Nurcan, Choi, Eun-Jin, Lim, Yung-Kyung, Kim, Su-Yung, Park, Yong Jun, Oh, Jin Won, Choi, Kyoung Min, Lee, Jong In, Song, Ji Sun, Hari, Pankaj, Bagga, Arvind, Gupta, Nandita, Mahajan, Puneet, Yadav, Anil, Fereshteh Nejad, Mohamad, Davitaia, Tinatin, Megrelishvili, Giuli, Manjavidze, Nino, Abdelraheem, Mohamed, Ali, Eltigani, Hassan, Einas, Ali, Maysoon, Mohamed, Ikhlas, Nazik, A.E., Hammad, Ayman, Sarhan, Amr, Bakr, Ashraf, El Refaay, Ahmed, El Mogy, Atef, Thrwat, Noha, El Husseiny, Fatma, Abd El Rahman, Ashraf, Cucer, Florentina, Brumariu, Ovidiu, Munteanu, Mihaela, Iliescu, Codruta, Muller, Robert, Bircan, Zelal, Mutlu, Hatice, Karacayir, Nihal, Cheong, H.I., Lima, Eleonora, Leite, A., Faria, S., Gomide, I., Mohkam, Masoumeh, Tabatabaii, Ahamd, Moinara, Raheleh, Emamghorashi, Fatemeh, Farshadi, Shohreh, Kalani, Mehdi, Gohel, Kalpesh, Hegde, Umapati, Gang, Sishir, Rajapurkar, Mohan, Acharya, Vidya, Desai, Mahesh |
| بيانات النشر: |
Oxford University Press |
| سنة النشر: |
2010 |
| المجموعة: |
HighWire Press (Stanford University) |
| مصطلحات موضوعية: |
Sunday |
| الوصف: |
INTRODUCTION AND AIMS: Relapses of nephrotic syndrome often follow viral infections, commonly of the upper respiratory tract. Based on the assumption that corticosteroids inhibit cytokine production, we examined, in a prospective randomized controlled trial, whether daily administration of maintenance prednisolone during infections, reduces relapse rates in children with frequently relapsing nephrotic syndrome. METHODS: Patients with idiopathic, frequently relapsing nephrotic syndrome eligible for therapy with prolonged alternate day (ad) prednisolone (0.5-0.7 mg/kg) with/without levamisole (2 mg/kg ad) were eligible. Stratified randomization (based on baseline treatment) was done to groups I (Intervention) or C (Control). During viral infections, patients in Gr.I were advised to take the same dose of prednisolone every day for 7 consecutive days; patients in Gr.C continued to receive ad prednisolone. Relapse was defined as 3+ proteinuria on 3 consecutive days&treated with prednisolone [2 mg/kg/d until remission (trace/nil protein for 3 days);1.5 mg/kg ad for 4-wk,then tapered]. Relapse considered infection-associated if it occurred within 2-weeks of onset of viral illness. Patients were followed for 12 months; intention to treat principle was used for analysis. RESULTS: Of 142 patients screened, 100 were included (50 each in Gr.I&C). The mean age at inclusion was 78.5± 32 and 81.7± 33 months respectively in Gr. I and C. The respective mean relapse rates in preceding 12 months were 3.4±0.4 and 3.5±0.4. 86 children completed the trial. Five were lost to follow up (3&2 in gr.I&gr.C); 9 required alternative treatment [cyclophosphamide(5), mycophenolate&tacrolimus(2 each)]. Patients in Gr.I showed significantly lower relapse rates (Table; mean difference 0.9 episodes/patient/yr; 95% CI 0.4-1.4). Majority (92%) infections were upper respiratory (226 in Gr.I, 161 in Gr.C). The number of infection-associated relapses was significantly lower in Gr.I (Table; mean difference 0.7; 95% CI 0.3-1.1). One ... |
| نوع الوثيقة: |
text |
| وصف الملف: |
text/html |
| اللغة: |
English |
| العلاقة: |
http://ckj.oxfordjournals.org/cgi/content/short/2/suppl_2/ii2245Test; http://dx.doi.org/10.1093/ndtplus/2.s2.36Test |
| DOI: |
10.1093/ndtplus/2.s2.36 |
| الإتاحة: |
https://doi.org/10.1093/ndtplus/2.s2.36Test
http://ckj.oxfordjournals.org/cgi/content/short/2/suppl_2/ii2245Test |
| حقوق: |
Copyright (C) 2010, European Renal Association - European Dialysis and Transplant Assoc |
| رقم الانضمام: |
edsbas.24E85B7A |
| قاعدة البيانات: |
BASE |
