المؤلفون: Boby, ML, Fearon, D, Ferla, M, Filep, M, Koekemoer, L, Robinson, MC, Chodera, JD, Lee, AA, London, N, von Delft, A, von Delft, F, Achdout, H, Aimon, A, Alonzi, DS, Arbon, R, Aschenbrenner, JC, Balcomb, BH, Bar-David, E, Barr, H, Ben-Shmuel, A, Bennett, J, Bilenko, VA, Borden, B, Boulet, P, Bowman, GR, Brewitz, L, Brun, J, Bvnbs, S, Calmiano, M, Carbery, A, Carney, DW, Cattermole, E, Chang, E, Chernyshenko, E, Clyde, A, Coffland, JE, Cohen, G, Cole, JC, Contini, A, Cox, L, Croll, TI, Cvitkovic, M, De Jonghe, S, Dias, A, Donckers, K, Dotson, DL, Douangamath, A, Duberstein, S, Dudgeon, T, Dunnett, LE, Eastman, P, Erez, N, Eyermann, CJ, Fairhead, M, Fate, G, Fedorov, O, Fernandes, RS, Ferrins, L, Foster, R, Foster, H, Fraisse, L, Gabizon, R, García-Sastre, A, Gawriljuk, VO, Gehrtz, P, Gileadi, C, Giroud, C, Glass, WG, Glen, RC, Glinert, I, Godoy, AS, Gorichko, M, Gorrie-Stone, T, Griffen, EJ, Haneef, A, Hassell Hart, S, Heer, J, Henry, M, Hill, M, Horrell, S, Huang, QYJ, Huliak, VD, Hurley, MFD, Israely, T, Jajack, A, Jansen, J, Jnoff, E, Jochmans, D, John, T, Kaminow, B, Kang, L, Kantsadi, AL, Kenny, PW, Kiappes, JL, Kinakh, SO, Kovar, B, Krojer, T, La, VNT, Laghnimi-Hahn, S, Lefker, BA, et, alia

المصدر: Science , 382 (6671) , Article eabo7201. (2023)

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10185794/2/Kiappes_Open%20science%20discovery%20of%20potent%20noncovalent%20SARS-CoV-2%20main%20protease%20inhibitors_AAM.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10185794Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10185794/2/Kiappes_Open%20science%20discovery%20of%20potent%20noncovalent%20SARS-CoV-2%20main%20protease%20inhibitors_AAM.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10185794Test/

المؤلفون: Jansen J., Reimer K. C., Nagai J. S., Varghese F. S., Overheul G. J., de Beer M., Roverts R., Daviran D., Fermin L. A. S., Willemsen B., Beukenboom M., Djudjaj S., von Stillfried S., van Eijk L. E., Mastik M., Bulthuis M., Dunnen W. D., van Goor H., Hillebrands J. -L., Triana S. H., Alexandrov T., Timm M. -C., van den Berge B. T., van den Broek M., Nlandu Q., Heijnert J., Bindels E. M. J., Hoogenboezem R. M., Mooren F., Kuppe C., Miesen P., Grunberg K., Ijzermans T., Steenbergen E. J., Czogalla J., Schreuder M. F., Sommerdijk N., Akiva A., Boor P., Puelles V. G., Floege J., Huber T. B., Achdout H., Aimon A., Bar-David E., Barr H., Ben-Shmuel A., Bennett J., Boby M. L., Borden B., Bowman G. R., Brun J., BVNBS S., Calmiano M., Carbery A., Cattermole E., Chernychenko E., Choder J. D., Clyde A., Coffland J. E., Cohen G., Cole J., Contini A., Cox L., Cvitkovic M., Dias A., Donckers K., Dotson D. L., Douangamath A., Duberstein S., Dudgeon T., Dunnett L., Eastman P. K., Erez N., Eyermann C. J., Fairhead M., Fate G., Fearon D., Federov O., Ferla M., Fernandes R. S., Ferrins L., Foster R., Foster H., Gabizon R., Garcia-Sastre A., Gawriljuk V. O., Gehrtz P., Gileadi C., Giroud C., Glass W. G., Glen R., Itai glinert, Godoy A. S., Gorichko M., Gorrie-Stone T., Griffen E. J., Hart S. H., Heer J., Henry M., Hill M., Horrell S., Hurley M. F. D., Israely T., Jajack A., Jnoff E., Jochmans D., John T., De Jonghe S., Kantsadi A. L., Kenny P. W., Kiappes J. L., Koekemoer L., Kovar B., Krojer T., Lee A. A., Lefker B. A., Levy H., London N., Lukacik P., Macdonald H. B., Maclean B., Malla T. R., Matviiuk T., McCorkindale W., McGovern B. L., Melamed S., Michurin O., Mikolajek H., Milne B. F., Morris A., Morris G. M., Morwitzer M. J., Moustakas D., Nakamura A. M., Neto J. B., Neyts J., Nguyen L., Noske G. D., Oleinikovas V., Oliva G., Owen D., Psenak V., Pai R., Pan J., Paran N., Perry B., Pingle M., Pinjari J., Politi B., Powell A., Puni R., Rangel V. L., Reddi R. N., Reid S. P., Resnick E., Ripka E. G., Robinson M. C., Robinson R. P., Rodriguez-Guerra J., Rosales R., Rufa D., Schofield C., Shafeev M., Shaikh A., Shi J., Shurrush K., Sing S., Sittner A., Skyner R., Smalley A., Smilova M. D., Solmesky L. J., Spencer J., Strain-Damarell C., Swamy V., Tamir H., Tennant R., Thompson W., Thompson A., Tomasia S., Tumber A., Vakonakis I., van Rij R. P., van Geel L., Vaschetto M., Vitner E. B., Voelz V., Volkamer A., von Delft F., von Delft A., Walsh M., Ward W., Weatherall C., Weiss S., White K. M., Wild C. F., Wittmann M., Wright N., Yahalom-Ronen Y., Zaidmann D., Zidane H., Zitzmann N., Costa I. G., Schneider R. K., Smeets B., Kramann R.

المساهمون: J. Jansen, K.C. Reimer, J.S. Nagai, F.S. Varghese, G.J. Overheul, M. de Beer, R. Rovert, D. Daviran, L.A.S. Fermin, B. Willemsen, M. Beukenboom, S. Djudjaj, S. von Stillfried, L.E. van Eijk, M. Mastik, M. Bulthui, W.D. Dunnen, H. van Goor, J.-. Hillebrand, S.H. Triana, T. Alexandrov, M.-. Timm, B.T. van den Berge, M. van den Broek, Q. Nlandu, J. Heijnert, E.M.J. Bindel, R.M. Hoogenboezem, F. Mooren, C. Kuppe, P. Miesen, K. Grunberg, T. Ijzerman, E.J. Steenbergen, J. Czogalla, M.F. Schreuder, N. Sommerdijk, A. Akiva, P. Boor, V.G. Puelle, J. Floege, T.B. Huber, H. Achdout, A. Aimon, E. Bar-David, H. Barr, A. Ben-Shmuel, J. Bennett, M.L. Boby, B. Borden, G.R. Bowman, J. Brun, S. Bvnb, M. Calmiano, A. Carbery, E. Cattermole, E. Chernychenko, J.D. Choder, A. Clyde, J.E. Coffland, G. Cohen, J. Cole, A. Contini, L. Cox, M. Cvitkovic, A. Dia, K. Doncker, D.L. Dotson, A. Douangamath, S. Duberstein, T. Dudgeon, L. Dunnett, P.K. Eastman, N. Erez, C.J. Eyermann, M. Fairhead, G. Fate, D. Fearon, O. Federov, M. Ferla, R.S. Fernande, L. Ferrin, R. Foster, H. Foster, R. Gabizon, A. Garcia-Sastre, V.O. Gawriljuk, P. Gehrtz, C. Gileadi, C. Giroud, W.G. Gla, R. Glen, G. Itai, A.S. Godoy, M. Gorichko, T. Gorrie-Stone, E.J. Griffen, S.H. Hart, J. Heer, M. Henry

مصطلحات موضوعية: chronic kidney disease, COVID-19, fibrosi, human iPSC kidney organoid, kidney injury, protease blocker, SARS-CoV-2, Human, Kidney, Organoid, Settore CHIM/06 - Chimica Organica, Settore MED/04 - Patologia Generale

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35032430; info:eu-repo/semantics/altIdentifier/wos/WOS:000753471000008; volume:29; issue:2; firstpage:217; lastpage:231.e8; numberofpages:15; journal:CELL STEM CELL; http://hdl.handle.net/2434/923989Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85123016842

الإتاحة: https://doi.org/10.1016/j.stem.2021.12.010Test
http://hdl.handle.net/2434/923989Test

المؤلفون: Jansen, J., Reimer, K.C., Nagai, J.S., Varghese, F.S., Overheul, G.J., de Beer, M., Roverts, R., Daviran, D., Fermin, L.A.S., Willemsen, B., Beukenboom, M., Djudjaj, S., von Stillfried, S., van Eijk, L.E., Mastik, M., Bulthuis, M., Dunnen, W.D., van Goor, H., Hillebrands, J.-L., Triana, S.H., Alexandrov, T., Timm, M.-C., van den Berge, B.T., van den Broek, M., Nlandu, Q., Heijnert, J., Bindels, E.M.J., Hoogenboezem, R.M., Mooren, F., Kuppe, C., Miesen, P., Grünberg, K., Ijzermans, T., Steenbergen, E.J., Czogalla, J., Schreuder, M.F., Sommerdijk, N., Akiva, A., Boor, P., Puelles, V.G., Floege, J., Huber, T.B., van Rij, R.P., Costa, I.G., Schneider, R.K., Smeets, B., Kramann, R., Achdout, H., Aimon, A., Bar-David, E., Barr, H., Ben-Shmuel, A., Bennett, J., Boby, M.L., Borden, B., Bowman, G.R., Brun, J., BVNBS, S., Calmiano, M., Carbery, A., Cattermole, E., Chernychenko, E., Choder, J.D., Clyde, A., Coffland, J.E., Cohen, G., Cole, J., Contini, A., Cox, L., Cvitkovic, M., Dias, A., Donckers, K., Dotson, D.L., Douangamath, A., Duberstein, S., Dudgeon, T., Dunnett, L., Eastman, P.K., Erez, N., Eyermann, C.J., Fairhead, M., Fate, G., Fearon, D., Federov, O., Ferla, M., Fernandes, R.S., Ferrins, L., Foster, R., Foster, H., Gabizon, R., Garcia-Sastre, A., Gawriljuk, V.O., Gehrtz, P., Gileadi, C., Giroud, C., Glass, W.G., Glen, R., Itai glinert, Godoy, A.S., Gorichko, M., Gorrie-Stone, T., Griffen, E.J., Hart, S.H., Heer, J., Henry, M., Hill, M., Horrell, S., Hurley, M.F.D., Israely, T., Jajack, A., Jnoff, E., Jochmans, D., John, T., De Jonghe, S., Kantsadi, A.L., Kenny, P.W., Kiappes, J.L., Koekemoer, L., Kovar, B., Krojer, T., Lee, A.A., Lefker, B.A., Levy, H., London, N., Lukacik, P., Macdonald, H.B., Maclean, B., Malla, T.R., Matviiuk, T., McCorkindale, W., McGovern, B.L., Melamed, S., Michurin, O., Mikolajek, H., Milne, B.F., Morris, A., Morris, G.M., Morwitzer, M.J., Moustakas, D., Nakamura, A.M., Neto, J.B., Neyts, J., Nguyen, L., Noske, G.D., Oleinikovas, V., Oliva, G., Owen, D., Psenak, V., Pai, R., Pan, J., Paran, N., Perry, B., Pingle, M., Pinjari, J., Politi, B., Powell, A., Puni, R., Rangel, V.L., Reddi, R.N., Reid, S.P., Resnick, E., Ripka, E.G., Robinson, M.C., Robinson, R.P., Rodriguez-Guerra, J., Rosales, R., Rufa, D., Schofield, C., Shafeev, M., Shaikh, A., Shi, J., Shurrush, K., Sing, S., Sittner, A., Skyner, R., Smalley, A., Smilova, M.D., Solmesky, L.J., Spencer, J., Strain-Damarell, C., Swamy, V., Tamir, H., Tennant, R., Thompson, W., Thompson, A., Tomasia, S., Tumber, A., Vakonakis, I., van Geel, L., Vaschetto, M., Vitner, E.B., Voelz, V., Volkamer, A., von Delft, F., von Delft, A., Walsh, M., Ward, W., Weatherall, C., Weiss, S., White, K.M., Wild, C.F., Wittmann, M., Wright, N., Yahalom-Ronen, Y., Zaidmann, D., Zidane, H., Zitzmann, N.

وصف الملف: text

العلاقة: https://eprints.whiterose.ac.uk/211975/1/PIIS1934590921005208.pdfTest; Jansen, J. orcid.org/0000-0003-0513-6102 , Reimer, K.C. orcid.org/0000-0002-7118-9133 , Nagai, J.S. orcid.org/0000-0002-7655-7206 et al. (208 more authors) (2022) SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids. Cell Stem Cell, 29 (2). 217-231.e8. ISSN 1934-5909

الإتاحة: https://eprints.whiterose.ac.uk/211975Test/
https://eprints.whiterose.ac.uk/211975/1/PIIS1934590921005208.pdfTest

المؤلفون: Boby, M.L., Fearon, D., Ferla, M., Filep, M., Koekemoer, L., Robinson, M.C., Chodera, J.D., Lee, A.A., London, N., Delft, A. von, Delft, F. von, Achdout, H., Aimon, A., Alonzi, D.S., Arbon, R., Aschenbrenner, J.C., Balcomb, B.H., Bar-David, E., Barr, H., Ben-Shmuel, A., Bennett, J., Bilenko, V.A., Borden, B., Boulet, P., Bowman, G.R., Brewitz, L., Brun, J., Bvnbs, S., Calmiano, M., Carbery, A., Carney, D.W., Cattermole, E., Chang, E., Chernyshenko, E., Clyde, A., Coffland, J.E., Cohen, G., Cole, J.C., Contini, A., Cox, L., Croll, T.I., Cvitkovic, M., Jonghe, S. De, Dias, A., Donckers, K., Dotson, D.L., Douangamath, A., Duberstein, S., Dudgeon, T., Dunnett, L.E., Eastman, P., Erez, N., Eyermann, C.J., Fairhead, M., Fate, G., Fedorov, O., Fernandes, R.S., Ferrins, L., Foster, R., Foster, H., Fraisse, L., Gabizon, R., García-Sastre, A., Gawriljuk, V.O., Gehrtz, P., Gileadi, C., Giroud, C., Glass, W.G., Glen, R.C., Glinert, I., Godoy, A.S., Gorichko, M., Gorrie-Stone, T., Griffen, E.J., Haneef, A., Hassell Hart, S, Heer, J., Henry, M., Hill, M., Horrell, S., Huang, Q.Y.J., Huliak, V.D., Hurley, M.F.D., Israely, T., Jajack, A., Jansen, J, Jnoff, E., Jochmans, D., John, T., Kaminow, B., Kang, L., Kantsadi, A.L., Kenny, P.W., Kiappes, J.L., Kinakh, S.O., Kovar, B., Krojer, T., La, V.N.T., Laghnimi-Hahn, S., Lefker, B.A., Levy, H., Lithgo, R.M., Logvinenko, I.G., Lukacik, P., Macdonald, H.B., MacLean, E.M., Makower, L.L., Malla, T.R., Marples, P.G., Matviiuk, T., McCorkindale, W., McGovern, B.L., Melamed, S., Melnykov, K.P., Michurin, O., Miesen, P., Mikolajek, H., Milne, B.F., Minh, D., Morris, A., Morris, G.M., Morwitzer, M.J., Moustakas, D., Mowbray, C.E., Nakamura, A.M., Neto, J.B., Neyts, J., Nguyen, L, Noske, G.D., Oleinikovas, V., Oliva, G., Overheul, G.J., Owen, C.D., Pai, R., Pan, J., Paran, N., Payne, A.M., Perry, B., Pingle, M., Pinjari, J., Politi, B., Powell, A., Pšenák, V., Pulido, I., Puni, R., Rangel, V.L., Reddi, R.N., Rees, P., Reid, S.P., Reid, L., Resnick, E., Ripka, E.G., Robinson, R.P., Rodriguez-Guerra, J., Rosales, R., Rufa, D.A., Saar, K., Saikatendu, K.S., Salah, E., Schaller, D., Scheen, J., Schiffer, C.A., Schofield, C.J., Shafeev, M., Shaikh, A., Shaqra, A.M., Shi, J., Shurrush, K., Singh, S., Sittner, A., Sjö, P., Skyner, R., Smalley, A., Smeets, B., Smilova, M.D., Solmesky, L.J., Spencer, J., Strain-Damerell, C., Swamy, V., Tamir, H., Taylor, J.C., Tennant, R.E., Thompson, W., Thompson, A., Tomásio, S., Tomlinson, C.W.E., Tsurupa, I.S., Tumber, A., Vakonakis, I., Rij, R.P. van, Vangeel, L., Varghese, F.S., Vaschetto, M., Vitner, E.B., Voelz, V., Volkamer, A., Walsh, M.A., Ward, W., Weatherall, C., Weiss, S., White, K.M., Wild, C.F., Witt, K.D., Wittmann, M., Wright, N., Yahalom-Ronen, Y., Yilmaz, N.K., Zaidmann, D., Zhang, I., Zidane, H., Zitzmann, N., Zvornicanin, S.N.

المصدر: Science, 382, 6671, pp. eabo7201

مصطلحات موضوعية: All institutes and research themes of the Radboud University Medical Center, Radboudumc 11: Renal disorders Pathology, Radboudumc 4: lnfectious Diseases and Global Health Medical Microbiology

العلاقة: https://repository.ubn.ru.nl/handle/2066/300172Test

الإتاحة: https://doi.org/10.1126/science.abo7201Test
https://repository.ubn.ru.nl/handle/2066/300172Test

المؤلفون: von Delft F, Ronen Gabizon, Wild Cf, Anastassia L. Kantsadi, Peter W. Kenny, Koekemoer L, Matteo P. Ferla, Noam Erez, Sharon Melamed, Adam Smalley, Gijs J. Overheul, Jag Paul Heer, Shaikh A, Tika R. Malla, R.S. Fernandes, Christopher J. Schofield, Moustakas D, Pai R, MacLean B, T. Krojer, Finny S. Varghese, Elad Bar-David, Hagit Achdout, Gregory R. Bowman, Lefker Ba, Kovar B, Charlie Weatherall, Tennant R, Griffen Ej, Yfat Yahalom-Ronen, Louise Dunnett, Emma Cattermole, Bvnbs S, Chernyshenko E, Ripka Eg, Kim Donckers, Efrat Resnick, Nir Paran, J. L. Kiappes, Einat B. Vitner, Dotson Dl, Mark Daniel Calmiano, Juliane Brun, Victor L. Rangel, Matthew F. D. Hurley, Richard Foster, Garrett M. Morris, Vaschetto M, Austin Clyde, Shay Weiss, Pan J, Nir London, William McCorkindale, Dudgeon T, Martin A. Walsh, Borden B, Haim Barr, John Spencer, Zaidmann D, Alice Douangamath, Robinson Rp, Alexandre Dias, John D. Chodera, Morris A, Marian V. Gorichko, Oleg Fedorov, V.O. Gawriljuk, Petra Lukacik, Puni R, Pinjari J, Shafeev M, Dirk Jochmans, Assa Sittner, T.J. Gorrie-Stone, White Km, Amir Ben-Shmuel, Ioannis Vakonakis, Boaz Politi, Rambabu N. Reddi, Joseph E. Coffland, Itai Glinert, Matthew C. Robinson, Ferrins L, Tomasio S, Alpha A. Lee, Khriesto A. Shurrush, Holly Foster, A. Aimon, Boby Ml, Andrea Volkamer, Alessandro Contini, Voelz, Tobias John, Galit Cohen, A.M. Nakamura, Horrell S, G.D. Noske, Jim Bennett, Oleg M. Michurin, Nicholas A. Wright, Smilova, von Delft A, Ward W, Haim Levy, Tomer Israely, Fate G, McGovern Bl, Anna Carbery, David R. Owen, Zidane H, Cox L, Michael Fairhead, Psenak, Carina Gileadi, Wittmann M, Morwitzer Mj, Solmesky Lj, Anthony Tumber, Robert C. Glen, Eric Jnoff, Reid Sp, Sukrit Singh, Steven De Jonghe, Claire Strain-Damerell, Jason C. Cole, A.J. Powell, Rosales R, Nicole Zitzmann, D. Fearon, Nguyen L, Rodriguez-Guerra J, Shirly Duberstein, Andrew Thompson, Johan Neyts, Benjamin Ian Perry, van Rij Rp, Jose Brandao Neto, William G. Glass, Rufa D, Charline Giroud, Peter Eastman, Hannah E. Bruce Macdonald, Glaucius Oliva, Mark A. Hill, Laura Vangeel, Jiye Shi, Hadas Tamir, R. Skyner, Mikolajek H, Adolfo García-Sastre, Oleinikovas, Pingle M, Henry M, Cvitkovic M, Milne Bf, Hart Sh, Eyermann Cj, Thompson W, Matviiuk T, Andre S. Godoy, Swamy, P. Gehrtz, Jajack A

مصطلحات موضوعية: Open science, Open knowledge, Protease, Structural biology, Drug discovery, Computer science, Non covalent, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine.medical_treatment, medicine, Protease inhibitor (pharmacology), Computational biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::378b6d7608ebe4f22cf964ef3c0dad99Test
https://doi.org/10.1101/2020.10.29.339317Test

المؤلفون: BOOTHE, D. M., BROWN, S. A., FATE, G. D., PIERCE, P. A., HANSON, B. J., AL‐ADHAMI, M., BOOTHE, H. W., HOWE, L. B., NGUYEN, J.

المصدر: Journal of Veterinary Pharmacology and Therapeutics ; volume 19, issue 6, page 491-494 ; ISSN 0140-7783 1365-2885

الإتاحة: https://doi.org/10.1111/j.1365-2885.1996.tb00088.xTest

المؤلفون: Cho, B.-Y., Strong, R., Fate, G., Krull, I. S.

المصدر: Journal of Chromatography B: Biomedical Sciences and Applications; 1997, Vol. 697 Issue: 1 p163-174, 12p

المؤلفون: Strong, R. A., Cho, B.-Y., Fate, G. D., Krull, I. S.

المصدر: Journal of Chromatography A; 1998, Vol. 824 Issue: 1 p25-33, 9p

المؤلفون: Groves, J. T., Fate, G. D., Lahiri, J.

المصدر: Journal of Inorganic Biochemistry; 1995, Vol. 59 Issue: 2-3 p261-261, 1p