المؤلفون: Hans-Peter Hammes, Elena Heidenreich, Peter P. Nawroth, Martina U. Muckenthaler, Sandro Altamura, Thomas Fleming, Andrea Schlotterer, Katja Müdder, Ruiyue Qiu

المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101235-(2021)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, DR, diabetic retinopathy, Hepcidin, medicine.disease_cause, Mice, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, MetS, Metabolic Syndrome, Internal medicine, biology, Fpn, Ferroportin, Fatty liver, Liver, DIOS, dysmetabolic iron overload syndrome, CRP, C-reactive protein, Receptors, Leptin, HH, hereditary hemochromatosis, Original Article, IRP, Iron Regulatory Protein, medicine.medical_specialty, Iron Overload, Iron, 030209 endocrinology & metabolism, Mice, Transgenic, IR, Insulin Resistance, SEM, standard error of the mean, 03 medical and health sciences, Insulin resistance, ROS, reactive oxygen species, NASH, Non Alcoholic Steatohepatitis, NAFLD, medicine, Animals, Humans, Molecular Biology, business.industry, NTBI, Non Transferrin Bound Iron, Cell Biology, medicine.disease, RC31-1245, IRS1, Db/db Mouse, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, NAFLD, Non Alcoholic Fatty Liver Disease, Lipid Peroxidation, Steatosis, Metabolic syndrome, business, Oxidative stress, IRE, Iron Responsive Element, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ad7abfa625d87337f2502f8e59462Test
http://www.sciencedirect.com/science/article/pii/S2212877821000806Test

المؤلفون: Simona Simmen, Jesus Cosin-Roger, Cheryl de Valliere, Katharina Spanaus, Katharina Baebler, Chiaki Maeyashiki, Nikolaos Maliachovas, Jonas Zeitz, Gerhard Rogler, Pedro A. Ruiz, Hassan Melhem, Stephan R. Vavricka, Bruce Weder, Max Maane, Martin Hausmann, Michael Scharl

المساهمون: University of Zurich, Ruiz, Pedro A

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 339-355 (2019)

مصطلحات موضوعية: 0301 basic medicine, DMT-1, divalent metal transporter 1, RNA Stability, Interleukin-1beta, IRE, iron-responsive elements, IEC, intestinal epithelial cell, 0302 clinical medicine, PCR, polymerase chain reaction, 540 Chemistry, IL1β, interleukin 1β, Intestinal Mucosa, Hypoxia, Promoter Regions, Genetic, 10038 Institute of Clinical Chemistry, Original Research, DFO, deferoxamine, Aged, 80 and over, TNF, tumor necrosis factor, biology, IBD, inflammatory bowel disease, Chemistry, TTP, tristetraprolin, Gastroenterology, NF-kappa B, Middle Aged, Intestinal epithelium, mRNA, messenger RNA, Cell biology, Oxygen tension, Deferoxamine, ChIP, chromatin immunoprecipitation, HIF, hypoxia-inducible transcription factor, 10219 Clinic for Gastroenterology and Hepatology, FPN, ferroportin, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, medicine.symptom, HT29 Cells, medicine.drug, Adult, Iron, NF-κB, nuclear factor-κB, 610 Medicine & health, Inflammation, mTOR, mammalian target of rapamycin, PHD, prolyl hydroxylase, Models, Biological, H2DCF-DA, 2′,7′-dichlorofluorescein diacetate, IRP, iron regulatory protein, 03 medical and health sciences, Young Adult, ROS, reactive oxygen species, Tf, transferrin, medicine, Autophagy, Humans, 2715 Gastroenterology, lcsh:RC799-869, Aged, Hepatology, Tumor Necrosis Factor-alpha, Inflammatory Bowel Disease, Transcription Factor RelA, Caco-2, Hypoxia (medical), LC3, light chain 3, Ferritin, FAC, ferric ammonion iron citrate, 030104 developmental biology, ARE, adenylate and uridylate-rich elements, biology.protein, 2721 Hepatology, lcsh:Diseases of the digestive system. Gastroenterology, Caco-2 Cells

وصف الملف: 1-s2.0-S2352345X18301528-main.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b468eae5dd78052ab560274d719c8cf0Test
http://europepmc.org/articles/PMC6357696Test

المؤلفون: Yan Wang, Yalin Wu, Zuguo Liu, Jingmeng Chen, Chao Chen

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, STEAP3, six-transmembrane epithelial antigen of prostate 3, genetic structures, STGD1, autosomal recessive Stargardt disease, TFRC, transferrin receptor, ONL, outer nuclear layer, Mitochondrion, medicine.disease_cause, Biochemistry, Photoreceptor cell, Mice, DMT1, Divalent metal transporter 1, GSH, glutathione, Stargardt Disease, oxidative stress, iron metabolism, AMD, age-related macular degeneration, IREB2, Iron-responsive element binding protein 2, POS, photoreceptor outer segments, chemistry.chemical_classification, Deferoxamine mesylate, LDH, lactate dehydrogenase, Chemistry, TEM, transmission electron microscope, lipid peroxidation, LED, light emitting diode, Cell biology, medicine.anatomical_structure, cell death, Retinaldehyde, Photoreceptor Cells, Vertebrate, Research Article, Programmed cell death, macular degeneration, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Animals, Ferroptosis, Molecular Biology, Reactive oxygen species, Retina, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, all-trans-retinal, photoreceptor, eye diseases, TF, transferrin, Mice, Inbred C57BL, 030104 developmental biology, CP, ceruloplasmin, atRAL, all-trans-retinal, H&E, hematoxylin and eosin, sense organs, FPN, Ferroportin, Reactive Oxygen Species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212aTest
https://pubmed.ncbi.nlm.nih.gov/33334878Test

المؤلفون: Shunsuke Hatta, Satoshi Ichikawa, Yasushi Onishi, Urara Ota, Noriko Fukuhara, Yoko Okitsu, Masahiro Kobayashi, Hideo Harigae, Kei Saito, Tohru Fujiwara, Tohru Tanaka, Masahiro Ishizuka

المصدر: Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 105-111 (2017)

مصطلحات موضوعية: 0301 basic medicine, 5-Aminolevulinic acid, Biophysics, SFC, sodium ferrous citrate, HO-1, heme oxygenase 1, Biochemistry, lcsh:Biochemistry, Caco-2 cell, 03 medical and health sciences, chemistry.chemical_compound, DMT1, divalent metal transporter 1, 0302 clinical medicine, RT-PCR, reverse transcription polymerase chain reaction, Biosynthesis, lcsh:QD415-436, lcsh:QH301-705.5, Heme, CSA, congenital sideroblastic anemia, Ferrous citrate, biology, Heme oxygenase 1, Metabolism, DMT1, ALAS2, Heme oxygenase, ChIP, chromatin immunoprecipitation, 030104 developmental biology, lcsh:Biology (General), chemistry, Caco-2, FPN, ferroportin, 030220 oncology & carcinogenesis, biology.protein, ALA, 5-aminolevulinic acid, Bach1, ALAS2, 5-aminolevulinic acid synthase 2, PP IX, protoporphyrin IX, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b82a9f47aca64455eb73801bac9a6aTest
https://pubmed.ncbi.nlm.nih.gov/28955775Test

المؤلفون: Patricia Huebbe, Jan Frank, Kathrin Pallauf, Dawn Chin, Gerald Rimbach

المصدر: Redox Biology, Vol 2, Iss C, Pp 563-569 (2014)
Redox Biology

مصطلحات موضوعية: Clinical Biochemistry, TBS, tris buffered saline, Pharmacology, Biochemistry, chemistry.chemical_compound, Mice, TfR1, transferrin receptor 1, Enlarged spleen, lcsh:QH301-705.5, HO1, haem oxygenase, lcsh:R5-920, biology, qRT-PCR, quantitative real-time polymerase chain reaction, Iron deficiency, γ-GCS, γ-glutamyl cysteine synthetase, NRF2, nuclear factor (erythroid-derived 2)-like 2, Zinc, medicine.anatomical_structure, Liver, FPN, ferroportin, TNFα, tumour necrosis factor α, Toxicity, Female, Safety, lcsh:Medicine (General), Research Paper, Curcumin, Liver minerals, Iron, Spleen, Transferrin receptor, NQO1, NAD(P)H quinone oxidoreductase, Drug Administration Schedule, DMT1, divalent metal transporter 1, Hepcidins, Hepcidin, medicine, Animals, Dose-Response Relationship, Drug, Organic Chemistry, Body Weight, DMT1, medicine.disease, Iron store, IL, interleukin, Ferritin, Mice, Inbred C57BL, chemistry, Gene Expression Regulation, lcsh:Biology (General), Immunology, Dietary Supplements, Ferritins, Splenomegaly, biology.protein, Copper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34111eb52cef8c02b7b58ec3fd7d6591Test
http://www.sciencedirect.com/science/article/pii/S2213231714000330Test

المؤلفون: Gautam Rishi, Daniel F. Wallace, V. Nathan Subramaniam

المصدر: Bioscience Reports
Bioscience Reports, Vol 35, Iss 3, p e00192 (2015)

مصطلحات موضوعية: ACD, anaemia of chronic disease, LSEC, liver sinusoidal endothelial cell, Ferroportin, lcsh:Life, lcsh:QR1-502, Smad Proteins, Review Article, Gene mutation, TNF, tumour necrosis factor, Biochemistry, lcsh:Microbiology, Mice, iron, hemic and lymphatic diseases, GDF15, growth differentiation factor 15, HJV, haemojuvelin, NPC, non-parenchymal cell, sHJV, soluble HJV, TFR, transferrin receptor, Internalization, Cation Transport Proteins, media_common, biology, Chemistry, Transferrin, PDGF-BB, platelet-derived growth factor-BB, Iron deficiency, HSC, hepatic stellate cell, Cell Hypoxia, Cell biology, HIF, hypoxia-inducible factor, STAT, signal transducer and activator of transcription, ATOH8, atonal homologue 8, FPN, ferroportin, pSMAD1/5/8, phospho-SMAD1/5/8, Bone Morphogenetic Proteins, LPS, lipopolysaccharide, Erythropoiesis, SMAD, sma and mothers against decapentaplegic homologue, Hemochromatosis, JAK, Janus kinase, PHD, prolyl dehydrogenase, Signal Transduction, media_common.quotation_subject, CREB/H, cAMP response element-binding protein/H, HRE, hypoxia-responsive element, IRIDA, iron refractory iron deficiency anaemia, Biophysics, mTOR, mammalian target of rapamycin, HEK, human embryonic kidney, HH, hereditary haemochromatosis, BMPR, BMP receptor, Hepcidins, Hepcidin, TGF-β, transforming growth factor-β, medicine, KC, Kupffer cell, Animals, Humans, ERFE, erythroferrone, Erythropoietin, Molecular Biology, TWSG1, twisted gastrulation BMP signalling modulator 1, Hemojuvelin, EGF, epidermal growth factor, Inflammation, hypoxia, BMP, bone morphogenetic protein, HFE, haemochromatosis protein, Cell Biology, medicine.disease, IL, interleukin, TF, transferrin, lcsh:QH501-531, VHL, von Hippel-Lindau, Immunology, biology.protein, HGF, hepatocyte growth factor, hepcidin, EPO, erythropoietin, Tmprss, transmembrane protease, serine, erythropoiesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6358457def4b1c58d16c877af1c35152Test
https://doi.org/10.1042/bsr20150014Test

المؤلفون: Giada Ingoglia, Fiorella Altruda, Lorenzo Silengo, Sonia Mercurio, Emanuela Tolosano, Deborah Chiabrando, Francesca Vinchi, Emilia Turco

المصدر: Gastroenterology

مصطلحات موضوعية: Cytochrome, Ferroportin, Dexamethasone, chemistry.chemical_compound, Mice, ALAS, 5-aminolevulinic acid synthase, Cytochrome P-450 Enzyme System, CYP, Homeostasis, Heme, Cation Transport Proteins, Fpn, ferroportin, Original Research, Mice, Knockout, biology, Gastroenterology, Imidazoles, mRNA, messenger RNA, Phenylhydrazines, Biochemistry, Enzyme Induction, Receptors, Virus, CYP, cytochrome P450, FLVCR, HO-1, Hemolysis, FLVCR1a, feline leukemia virus subgroup C cellular receptor 1a, Benzo(a)pyrene, Animals, Heme export, HO, heme oxygenase, RNA, Messenger, Enzyme inducer, Hepatology, Full Report: Basic and Translational—Liver, ALAS1, Cytochrome P450, Membrane Proteins, Membrane Transport Proteins, Flvcr1, Molecular biology, Heme oxygenase, chemistry, Be(a)P, benzo(a)pyrene, Ferritins, biology.protein, Hepatocytes, ALA, 5-aminolevulinic acid, Liver function, Heme Oxygenase-1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5067ade43b092e13b386c129d0b91fe3Test
http://hdl.handle.net/2318/146913Test