المؤلفون: Sandholm, Niina, Cole, Joanne B, Nair, Viji, Sheng, Xin, Liu, Hongbo, Ahlqvist, Emma, van Zuydam, Natalie, Dahlström, Emma H, Fermin, Damian, Smyth, Laura J, Salem, Rany M, Forsblom, Carol, Valo, Erkka, Harjutsalo, Valma, Brennan, Eoin P, McKay, Gareth J, Andrews, Darrell, Doyle, Ross, Looker, Helen C, Nelson, Robert G, Palmer, Colin, McKnight, Amy Jayne, Godson, Catherine, Maxwell, Alexander P, Groop, Leif, McCarthy, Mark I, Kretzler, Matthias, Susztak, Katalin, Hirschhorn, Joel N, Florez, Jose C, Groop, Per-Henrik

المصدر: Diabetologia. 65(9)

مصطلحات موضوعية: Human Genome, Kidney Disease, Prevention, Genetics, Diabetes, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Renal and urogenital, Metabolic and endocrine, Good Health and Well Being, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Doublecortin-Like Kinases, Fibrosis, Genome-Wide Association Study, Humans, Intracellular Signaling Peptides and Proteins, Kidney, Polymorphism, Single Nucleotide, Protein Serine-Threonine Kinases, Diabetes complications, Diabetic kidney disease, Genome-wide association study, Meta-analysis, Transcriptomics, GENIE Consortium, Genome-wide association study, Meta-analysis, Transcriptomics, Clinical Sciences, Paediatrics and Reproductive Medicine, Public Health and Health Services, Endocrinology & Metabolism

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7kb0h2rrTest

المؤلفون: Smyth, Laura J, Dahlström, Emma H, Syreeni, Anna, Kerr, Katie, Kilner, Jill, Doyle, Ross, Brennan, Eoin, Nair, Viji, Fermin, Damian, Nelson, Robert G, Looker, Helen C, Wooster, Christopher, Andrews, Darrell, Anderson, Kerry, McKay, Gareth J, Cole, Joanne B, Salem, Rany M, Conlon, Peter J, Kretzler, Matthias, Hirschhorn, Joel N, Sadlier, Denise, Godson, Catherine, Florez, Jose C, Forsblom, Carol, Maxwell, Alexander P, Groop, Per-Henrik, Sandholm, Niina, McKnight, Amy Jayne

المصدر: Nature Communications. 13(1)

مصطلحات موضوعية: Biological Sciences, Genetics, Autoimmune Disease, Diabetes, Human Genome, Kidney Disease, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Renal and urogenital, Humans, DNA Methylation, Epigenome, Diabetic Nephropathies, Epigenesis, Genetic, Diabetes Mellitus, Type 1, Biomarkers, DNA, Genome-Wide Association Study, CpG Islands, GENIE consortium

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4tf5g8kzTest

المؤلفون: Dwivedi, Om Prakash, Barreiro, Karina, Käräjämäki, Annemari, Valo, Erkka, Giri, Anil K., Prasad, Rashmi B., Roy, Rishi Das, Thorn, Lena M., Rannikko, Antti, Holthöfer, Harry, Gooding, Kim M., Sourbron, Steven, Delic, Denis, Gomez, Maria F., Groop, Per-Henrik, Tuomi, Tiinamaija, Forsblom, Carol, Groop, Leif, Puhka, Maija

المصدر: iScience EXODIAB: Excellence of Diabetes Research in Sweden eSSENCE: The e-Science Collaboration. 26(5)

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes

الوصول الحر: https://lup.lub.lu.se/record/65011b76-a279-4b40-8e82-3ef0bcbaf801Test
http://dx.doi.org/10.1016/j.isci.2023.106686Test

المؤلفون: Sandholm, Niina, Forsblom, Carol

المساهمون: Tecilazich, Francesco, HUS Abdominal Center, CAMM - Research Program for Clinical and Molecular Metabolism, Medicum, Research Programs Unit, Clinicum

مصطلحات موضوعية: Diabetic nephropathy, Diabetic retinopathy, End-stage renal disease, Genetics, Gwas, Microvascular complications, Neuropathy, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: Microvascular Disease in Diabetes; Sandholm , N & Forsblom , C 2020 , Genetics of diabetic microvascular disease . in F Tecilazich (ed.) , Microvascular Disease in Diabetes . Wiley , pp. 23-44 . https://doi.org/10.1002/9781119309642.ch3Test; ORCID: /0000-0003-4322-6942/work/109265464; http://hdl.handle.net/10138/353778Test; 9d9cd702-6306-4199-9c4c-a4d731c3282e; 85101489847

الإتاحة: http://hdl.handle.net/10138/353778Test

المؤلفون: FinnDiane Study Grp, Harjutsalo, Valma, Kallio, Milla, Forsblom, Carol, Groop, Per-Henrik

المساهمون: Research Programs Unit, Medicum, Clinicum, HUS Abdominal Center, Nefrologian yksikkö, CAMM - Research Program for Clinical and Molecular Metabolism, Verisuonikirurgian yksikkö, Department of Medicine, Per Henrik Groop / Principal Investigator

مصطلحات موضوعية: Chronic limb threatening ischemia, Claudication, Diabetic foot, Diabetic nephropathy, Diabetic retinopathy, Foot ulcers, Gangrene, Lower extremity amputation, Peripheral artery disease, Type 1 diabetes, Ulceration, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: FinnDiane Study Grp , Harjutsalo , V , Kallio , M , Forsblom , C & Groop , P-H 2023 , ' The impact of diabetic nephropathy and severe diabetic retinopathy on chronic limb threatening ischemia risk in individuals with type 1 diabetes : a nationwide, population ' , Lancet regional health.Europe , vol. 28 , 100594 . https://doi.org/10.1016/j.lanepe.2023.100594Test; http://hdl.handle.net/10138/564708Test; e051676a-a93a-4198-957d-6cf63f3d414a; 001044118400001

الإتاحة: http://hdl.handle.net/10138/564708Test

المؤلفون: Khurana, Ishant, Kaipananickal, Harikrishnan, Maxwell, Scott, Birkelund, Sorine, Syreeni, Anna, Forsblom, Carol, Okabe, Jun, Ziemann, Mark, Kaspi, Antony, Rafehi, Haloom, Jorgensen, Anne, Al-Hasani, Keith, Thomas, Merlin C., Jiang, Guozhi, Luk, Andrea O. Y., Lee, Heung Man, Huang, Yu, Thewjitcharoen, Yotsapon, Nakasatien, Soontaree, Himathongkam, Thep, Fogarty, Christopher, Njeim, Rachel, Eid, Assaad, Hansen, Tine Willum, Tofte, Nete, Ottesen, Evy C., Ma, Ronald C. W., Chan, Juliana C. N., Cooper, Mark E., Rossing, Peter, Groop, Per-Henrik, El-Osta, Assam

المساهمون: Research Programs Unit, HUS Abdominal Center, Medicum, Nefrologian yksikkö, CAMM - Research Program for Clinical and Molecular Metabolism, Helsinki University Hospital Area, Department of Medicine, Per Henrik Groop / Principal Investigator, Clinicum

مصطلحات موضوعية: Chronic kidney-disease, Dna methylation, Ctcf, Microalbuminuria, Association, Complications, Nephropathy, Hyperglycemia, Mortality, Mellitus, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: Khurana , I , Kaipananickal , H , Maxwell , S , Birkelund , S , Syreeni , A , Forsblom , C , Okabe , J , Ziemann , M , Kaspi , A , Rafehi , H , Jorgensen , A , Al-Hasani , K , Thomas , M C , Jiang , G , Luk , A O Y , Lee , H M , Huang , Y , Thewjitcharoen , Y , Nakasatien , S , Himathongkam , T , Fogarty , C , Njeim , R , Eid , A , Hansen , T W , Tofte , N , Ottesen , E C , Ma , R C W , Chan , J C N , Cooper , M E , Rossing , P , Groop , P-H & El-Osta , A 2023 , ' Reduced methylation correlates with diabetic nephropathy risk in 1 diabetes ' , Journal of Clinical Investigation , vol. 133 , no. 4 , e160959 . https://doi.org/10.1172/JCI160959Test; ORCID: /0000-0003-1857-2560/work/138701434; http://hdl.handle.net/10138/563334Test; 2d4b72e2-bff2-4550-b0fb-5edd65878759; 000996468100004

الإتاحة: http://hdl.handle.net/10138/563334Test

المؤلفون: Syreeni, Anna, Dahlström, Emma H., Hägg-Holmberg, Stefanie, Forsblom, Carol, Eriksson, Marika I, Harjutsalo, Valma, Putaala, Jukka, Groop, Per-Henrik, Sandholm, Niina, Thorn, Lena

المساهمون: Research Programs Unit, HUS Abdominal Center, CAMM - Research Program for Clinical and Molecular Metabolism, Nefrologian yksikkö, HUS Internal Medicine and Rehabilitation, HUS Neurocenter, Clinicum, Department of Neurosciences, Neurologian yksikkö, Department of Medicine, Per Henrik Groop / Principal Investigator, Medicum, Doctoral Programme in Clinical Research, Department of General Practice and Primary Health Care

مصطلحات موضوعية: General medicine, internal medicine and other clinical medicine, Genetics, Diabetes Complications, stroke

وصف الملف: application/pdf

العلاقة: Syreeni , A , Dahlström , E H , Hägg-Holmberg , S , Forsblom , C , Eriksson , M I , Harjutsalo , V , Putaala , J , Groop , P-H , Sandholm , N & Thorn , L 2022 , ' Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes ' , Diabetes , vol. 71 , no. 12 , pp. 2728-2738 . https://doi.org/10.2337/db22-0327Test; ORCID: /0000-0003-3999-0390/work/130150949; ORCID: /0000-0003-4322-6942/work/130151430; ORCID: /0000-0003-1857-2560/work/130151718; ORCID: /0000-0003-1271-8696/work/130152598; http://hdl.handle.net/10138/353897Test; 7476a1f0-0e5c-4f6c-b9ab-af39ddf9223d; 000905189200029

الإتاحة: http://hdl.handle.net/10138/353897Test

المؤلفون: GENIE Consortium, Smyth, Laura J., Dahlström, Emma H., Syreeni, Anna, Kerr, Katie, Kilner, Jill, Doyle, Ross, Brennan, Eoin, Nair, Viji, Fermin, Damian, Nelson, Robert G., Looker, Helen C., Wooster, Christopher, Andrews, Darrell, Anderson, Kerry, McKay, Gareth J., Cole, Joanne B., Salem, Rany M., Conlon, Peter J., Kretzler, Matthias, Hirschhorn, Joel N., Sadlier, Denise, Godson, Catherine, Florez, Jose C., Forsblom, Carol, Maxwell, Alexander P., Groop, Per-Henrik, Sandholm, Niina, McKnight, Amy Jayne

المساهمون: Research Programs Unit, HUS Internal Medicine and Rehabilitation, HUS Abdominal Center, Nefrologian yksikkö, CAMM - Research Program for Clinical and Molecular Metabolism, Medicum, Clinicum, Institute for Molecular Medicine Finland, Department of Medicine, Per Henrik Groop / Principal Investigator

مصطلحات موضوعية: Nephropathy, Loci, Progression, Expression, Losartan, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: GENIE Consortium , Smyth , L J , Dahlström , E H , Syreeni , A , Kerr , K , Kilner , J , Doyle , R , Brennan , E , Nair , V , Fermin , D , Nelson , R G , Looker , H C , Wooster , C , Andrews , D , Anderson , K , McKay , G J , Cole , J B , Salem , R M , Conlon , P J , Kretzler , M , Hirschhorn , J N , Sadlier , D , Godson , C , Florez , J C , Forsblom , C , Maxwell , A P , Groop , P-H , Sandholm , N & McKnight , A J 2022 , ' Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease ' , Nature Communications , vol. 13 , no. 1 , 7891 . https://doi.org/10.1038/s41467-022-34963-6Test; ORCID: /0000-0003-4322-6942/work/135802311; ORCID: /0000-0003-1857-2560/work/135802654; ORCID: /0000-0003-1271-8696/work/135802979; 9092d152-8d6f-47b5-adbe-523b31a4c023; http://hdl.handle.net/10138/358064Test; 000972743600002

الإتاحة: http://hdl.handle.net/10138/358064Test

المؤلفون: Mychaleckyj, Josyf C., Valo, Erkka, Ichimura, Takaharu, Ahluwalia, Tarunveer S., Dina, Christian, Miller, Rachel G., Shabalin, Ivan G., Gyorgy, Beata, Cao, JingJing, Onengut-Gumuscu, Suna, Satake, Eiichiro, Smiles, Adam M., Haukka, Jani K., Tregouet, David-Alexandre, Costacou, Tina, O'Neil, Kristina, Paterson, Andrew D., Forsblom, Carol, Keenan, Hillary A., Pezzolesi, Marcus G., Pragnell, Marlon, Galecki, Andrzej, Rich, Stephen S., Sandholm, Niina, Klein, Ronald, Klein, Barbara E., Susztak, Katalin, Orchard, Trevor J., Korstanje, Ron, King, George L., Hadjadj, Samy, Rossing, Peter, Bonventre, Joseph V., Groop, Per-Henrik, Warram, James H., Krolewski, Andrzej S.

المساهمون: CAMM - Research Program for Clinical and Molecular Metabolism, HUS Abdominal Center, Nefrologian yksikkö, Research Programs Unit, Clinicum, Medicum, Department of Medicine, Per Henrik Groop / Principal Investigator

مصطلحات موضوعية: type 1 diabetes, hydroxysteroid 17-beta dehydrogenase 14, end stage kidney disease, gene-based tests, rare variants, diabetic nephropathy, diabetic kidney disease, GENOME-WIDE ASSOCIATION, RENAL DECLINE, NEPHROPATHY, COMPLICATIONS, RISK, MICROALBUMINURIA, PREDICTORS, GENETICS, DURATION, GENES, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: Mychaleckyj , J C , Valo , E , Ichimura , T , Ahluwalia , T S , Dina , C , Miller , R G , Shabalin , I G , Gyorgy , B , Cao , J , Onengut-Gumuscu , S , Satake , E , Smiles , A M , Haukka , J K , Tregouet , D-A , Costacou , T , O'Neil , K , Paterson , A D , Forsblom , C , Keenan , H A , Pezzolesi , M G , Pragnell , M , Galecki , A , Rich , S S , Sandholm , N , Klein , R , Klein , B E , Susztak , K , Orchard , T J , Korstanje , R , King , G L , Hadjadj , S , Rossing , P , Bonventre , J V , Groop , P-H , Warram , J H & Krolewski , A S 2021 , ' Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes ' , Journal of the American Society of Nephrology , vol. 32 , no. 10 , pp. 2634-2651 . https://doi.org/10.1681/ASN.2020101457Test; ORCID: /0000-0003-4322-6942/work/104579661; ORCID: /0000-0003-0672-554X/work/104579913; ddefafdd-ec8f-46d7-a02b-843a1a963f96; http://hdl.handle.net/10138/353497Test; 000714146900027

الإتاحة: http://hdl.handle.net/10138/353497Test

المؤلفون: Tarkkonen, Aleksi, Claesson, Tor-Björn, Eriksson, Marika I., Forsblom, Carol, Thorn, Lena M., Summanen, Paula, Groop, Per-Henrik, Putaala, Jukka, Gordin, Daniel, Martola, Juha

المساهمون: HUS Medical Imaging Center, Medicum, Clinicum, Research Programs Unit, Nefrologian yksikkö, CAMM - Research Program for Clinical and Molecular Metabolism, HUS Abdominal Center, Department of General Practice and Primary Health Care, HUS Head and Neck Center, Silmäklinikka, Department of Medicine, Per Henrik Groop / Principal Investigator, HUS Neurocenter, Department of Neurosciences, Neurologian yksikkö

مصطلحات موضوعية: Cerebral microbleeds, Cerebrovascular disease, Diabetic neuropathy, Diabetic retinopathy, Magnetic resonance imaging, Neuroradiology, Optic chiasm, Type 1 diabetes, 3121 General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: Tarkkonen , A , Claesson , T-B , Eriksson , M I , Forsblom , C , Thorn , L M , Summanen , P , Groop , P-H , Putaala , J , Gordin , D & Martola , J 2023 , ' Atrophy of the optic chiasm is associated with microvascular diabetic complications in type 1 diabetes ' , Frontiers in Endocrinology , vol. 14 , 1134530 . https://doi.org/10.3389/fendo.2023.1134530Test; ORCID: /0000-0003-3999-0390/work/138700846; ORCID: /0000-0003-1494-8292/work/138700946; 89997eab-898e-4ed9-8b38-59b48891d9c4; http://hdl.handle.net/10138/563258Test; 001006610300001

الإتاحة: http://hdl.handle.net/10138/563258Test