المؤلفون: Kaidonis, Georgia, Pekmezci, Melike, Van Ziffle, Jessica, Auguste, Kurtis I, Horton, Jonathan C

المصدر: Journal of Neurosurgery Case Lessons. 3(23)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Clinical Research, Rare Diseases, Human Genome, Brain Disorders, AKT1 = v-akt murine thymoma viral oncogene homolog 1, CHEK2 = checkpoint kinase 2, FGFR = fibroblast growth factor receptor, FUBP1 = far upstream element protein 1, IDO = indoleamine 2, 3-dioxygenase, KLF4 = Krupple-like factor 4, MEKK3 = mitogen-activated kinase kinase kinase 3, MRI = magnetic resonance imaging, NF2 = neurofibromatosis type 2, PD-L1 = programmed death-ligand 1, SMAD = some mothers again decapentaplegic, SMO = smoothened, frizzled family receptor, TDO2 = tryptophan 2, 3-dioxygenase, TRAF7 = tumor necrosis factor receptor-associated factor 7, TRAF7 syndrome, TWIST1 = Twist Family BHLH Transcription Factor 1, WD40 domain, craniosynostosis, meningiomatosis, mosaicism, p.R641C, pTERT = telomerase reverse transcriptase

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3bh8x3r7Test

المؤلفون: Daniel Barmas-Alamdari, George Jiao, Ronni Lieberman

المصدر: Frontiers in Ophthalmology, Vol 3 (2024)

مصطلحات موضوعية: pemigatinib, subretinal fluid, FGFR (fibroblast growth factor receptor), FGFR inhibitor, pigment epithelial detachment, Pemazyre, Medicine

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fopht.2023.1247296/fullTest; https://doaj.org/toc/2674-0826Test

الوصول الحر: https://doaj.org/article/7a561a7fe9e7417f97bed9f420450cf9Test

المؤلفون: Yiming Zhou, Sizheng Sun, Tao Ling, Yongzhen Chen, Rongzhong Zhou, Qiang You

المصدر: Frontiers in Oncology, Vol 13 (2023)

مصطلحات موضوعية: FGF18, (FGFR) fibroblast growth factor receptor, cancer, gene expression, pathway, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2023.1124520/fullTest; https://doaj.org/toc/2234-943XTest

الوصول الحر: https://doaj.org/article/0f47c04a963248a0b39c6c4771914fdcTest

المؤلفون: Giovanni Vitale, Alessia Cozzolino, Pasqualino Malandrino, Roberto Minotta, Giulia Puliani, Davide Saronni, Antongiulio Faggiano, Annamaria Colao

المصدر: Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: neuroendocrine neoplasms, FGFR (fibroblast growth factor receptor), FGF (fibroblast growth factor), VEGF - vascular endothelial growth factor, VEGFR - vascular endothelial growth factor receptor, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2021.665631/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/8bf131702f3949a9a1b072c1a744f288Test

المؤلفون: Vitale, Giovanni, Cozzolino, Alessia, Malandrino, Pasqualino, Minotta, Roberto, Puliani, Giulia, Saronni, Davide, Faggiano, Antongiulio, Colao, Annamaria

المساهمون: Vitale, Giovanni, Cozzolino, Alessia, Malandrino, Pasqualino, Minotta, Roberto, Puliani, Giulia, Saronni, Davide, Faggiano, Antongiulio, Colao, Annamaria

مصطلحات موضوعية: neuroendocrine neoplasm, fgfr (fibroblast growth factor receptor), fgf (fibroblast growth factor), vegf - vascular endothelial growth factor, vegfr - vascular endothelial growth factor receptor

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33935975; info:eu-repo/semantics/altIdentifier/wos/WOS:000644845700001; volume:12; issue:Apr 14; firstpage:1; lastpage:9; numberofpages:9; journal:FRONTIERS IN ENDOCRINOLOGY; http://hdl.handle.net/11573/1544288Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85104988285

الإتاحة: https://doi.org/10.3389/fendo.2021.665631Test
http://hdl.handle.net/11573/1544288Test

المؤلفون: Yunju Nam, Injae Shin, Younghoon Kim, SeongShick Ryu, Namdoo Kim, Eunhye Ju, Taebo Sim

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 1, Pp 34-49 (2022)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Models, Molecular, Cancer Research, Carcinoma, Hepatocellular, FGFR, fibroblast growth factor receptor, Molecular Conformation, Antineoplastic Agents, Apoptosis, Pyrimidinones, FGFR4 kinase, KLB, klotho beta, Structure-Activity Relationship, Cell Movement, Cell Line, Tumor, Humans, Receptor, Fibroblast Growth Factor, Type 4, HCC, RC254-282, Cell Proliferation, Original Research, Dose-Response Relationship, Drug, Molecular Structure, FGFR4 inhibitor, Liver Neoplasms, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell Cycle Checkpoints, digestive system diseases, FGF, fibroblast growth factor, GNF-7, HCC, hepatocellular carcinoma, EMT, epithelial-mesenchymal transition, Signal Transduction, PARP, poly (ADP-ribose) polymerase, SAR

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4404b111edeadaa6237d4a7297c304eTest
https://doi.org/10.1016/j.neo.2021.11.011Test

المؤلفون: Chenxi Zhao, Hong Zhu, Xiaoyang Dai, Weihua Wang, Meijia Qian, Xin Dong, Nengming Lin, Jiao Wang, Jiabin Lu, Bo Yang, Qiaojun He, Xiaowu Dong, Fangjie Yan, Tao Yuan, Bo Zhang, Jiamin Du, Ruilin Wu

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 4008-4019 (2021)

مصطلحات موضوعية: CCA, cholangiocarcinoma, FGFR, fibroblast growth factor receptor, TAZ, transcriptional co-activator with PDZ-binding motif, KRAS, kirsten rat sarcoma 2 viral oncogene homolog, PBS, phosphate-buffered saline, LATS1/2, large tumor suppressor kinase 1/2, RM1-950, Protein Homeostasis, Positive correlation, Deubiquitinating enzyme, Cholangiocarcinoma, rhJOSD2, recombinant human JOSD2, JOSD2, parasitic diseases, PDC, patient derived cell, medicine, YAP/TAZ, RTV, relative tumor volume, General Pharmacology, Toxicology and Pharmaceutics, DAB, 3,3-diaminobenzidine tetrahydrochloride chromogen, PDX, patient-derived xenograft, shRNA, specific hairpin RNA, biology, DUB, deubiquitinase, Protein level, Cancer, IP, immunoprecipitation, OTUB2, otubain-2, medicine.disease, Deubiquitinase, YAP, Yes-associated protein, FOLFOX, folinic acid, 5-FU and oxaliplatin, MST1/2, mammalian Ste20-like kinases 1/2, USP9X/10/47, ubiquitin-specific peptidase 9X/10/47, Cancer research, biology.protein, SRB, sulforhodamine B, IDH1/2, isocitrate dehydrogenase 1/2, TCGA, The Cancer Genome Atlas, Original Article, Therapeutics. Pharmacology, Malignant progression, YOD1, ubiquitin thioesterase OTU1, IHC, immunohistochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626f01f78adbe5f9659fdd17326d365aTest
http://europepmc.org/articles/PMC8727894Test

المؤلفون: Alexandre Gries, Michael A. Grotzer, Anuja Neve, Marc Thomas Schönholzer, Min Ma, Karthiga Santhana Kumar, Martin Baumgartner, Jessica Migliavacca, Elena Alvarez

المساهمون: University of Zurich, Baumgartner, Martin

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 10, Pp 470-483 (2020)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, ERK, Extracellular regulated kinase, Basic fibroblast growth factor, Dasatinib, Apoptosis, Cerebellum slice culture, SHH, sonic hedgehog, c-Met, cellular mesenchymal epithelial transition factor, chemistry.chemical_compound, 0302 clinical medicine, bFGF, basic fibroblast growth factor, Epidermal growth factor, Cell Movement, hemic and lymphatic diseases, Tumor Cells, Cultured, 1306 Cancer Research, Kinase, Cell migration, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Hepatocyte growth factor, Mitogen-Activated Protein Kinases, medicine.drug, Nuclear ERK1/2 activation sensor, Original article, FGFR, fibroblast growth factor receptor, MAP Kinase Signaling System, 610 Medicine & health, Antineoplastic Agents, lcsh:RC254-282, 03 medical and health sciences, medicine, Humans, Neoplasm Invasiveness, Protein kinase A, Fluorescent biosensor, Live cell imaging, Cerebellar Neoplasms, Cell Proliferation, EGF, epidermal growth factor, MB, medulloblastoma, SKARS, Synthetic Kinase Activation Relocation Sensor, 030104 developmental biology, WST, water soluble tetrazolium salt, chemistry, FDA, food and drug administration, 10036 Medical Clinic, MAPK, mitogen-activated protein kinases, Cancer research, JNK, c-jun N-terminal kinase, HGF, hepatocyte growth factor, Medulloblastoma

وصف الملف: 1-s2.0-S1476558620301378-main.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a076863a1a0810fcffc300433bde15bTest
http://europepmc.org/articles/PMC7452206Test

المؤلفون: Dhanya Raveendra-Panickar, Darren Finlay, Fabiana Izidro Layng, Lester J. Lambert, Maria Celeridad, Ming Zhao, Karina Barbosa, Laurent J.S. De Backer, Elizabeth Kwong, Palak Gosalia, Socorro Rodiles, John Holleran, Robert Ardecky, Stefan Grotegut, Steven Olson, John H. Hutchinson, Elena B. Pasquale, Kristiina Vuori, Aniruddha J. Deshpande, Nicholas D.P. Cosford, Lutz Tautz

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: PTS, protein thermal shift, Carcinogenesis, Protein Tyrosine Phosphatase, Non-Receptor Type 11, PTPN11, DMF, N,N-dimethylformamide, DMSO, dimethyl sulfoxide, protein tyrosine phosphatase, ERK, extracellular signal–regulated kinase, Biochemistry, AML, DiFMUP, 6,8-difluoro-4-methylumbelliferyl phosphate, EtOAc, ethyl acetate, TBS-T, Tris-buffered saline–Tween-20, anticancer drug, Enzyme Inhibitors, AML, acute myeloid leukemia, STEP, striatal-enriched tyrosine phosphatase, AIC, Akaike's Information Criterion, ESI, electrospray ionization, SH2, Src-homology 2, leukemia, IRS-1, insulin receptor substrate 1, SHP2cat, SHP2 catalytic domain, inhibitor, Leukemia, Myeloid, Acute, Benzamides, RT, room temperature, RTK, receptor tyrosine kinase, PTP, protein tyrosine phosphatase, THF, tetrahydrofuran, Research Article, N-SH2, N-terminal SH2 domain, FGFR, fibroblast growth factor receptor, sgRNA, single-guide RNA, OMFP, 3-O-methylfluorescein phosphate, small molecule, chemical biology, TNBC, triple-negative breast cancer, breast cancer, FBS, fetal bovine serum, SAR, structure–activity relationship, SHP2, Src-homology 2 domain–containing phosphatase 2, Humans, EDC, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, Molecular Biology, RFU, relative fluorescence unit, pTyr, phosphotyrosine, SHP2-WT, full-length SHP2 WT, Cell Biology, Oncogenes, AICc, second-order corrected Akaike’s Information Criterion, SHP2, DIEA, N,N-diisopropylethylamine, p-ERK1/2, phospho-ERK1/2, HOBt, hydroxybenzotriazole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29990762ad8fbd140f872fdc58a3cd6Test
http://europepmc.org/articles/PMC8760490Test

المؤلفون: Jacek Otlewski, Karolina Jendryczko, Anna Szlachcic, Mateusz Adam Krzyscik, Jakub Szymczyk, Jakub Rzeszotko

المصدر: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: cytotoxic conjugates, media_common.quotation_subject, Peptide, Computational biology, RM1-950, FGF4, targeting peptides, peptibodies, Interactome, peptide Fc fusions, Pharmacology (medical), Internalization, media_common, Original Research, chemistry.chemical_classification, Pharmacology, Fibroblast growth factor receptor 1, FGFR (fibroblast growth factor receptor), Fragment crystallizable region, targeted therapies, stomatognathic diseases, FGFR1, chemistry, Fibroblast growth factor receptor, Drug delivery, Cancer cell, Therapeutics. Pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b60f7af4288584394b19e3f55751e0Test
http://europepmc.org/articles/PMC8636100Test