Insulin pump therapy in children and adolescents: improvements in key parameters of diabetes management including quality of life
| العنوان: | Insulin pump therapy in children and adolescents: improvements in key parameters of diabetes management including quality of life |
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| المؤلفون: | Timothy W. Jones, F.L. Airey, D.A. Marangou, Sarah K. McMahon, Elizabeth A. Davis, Christine L. Carne, A.J. Clarey, K.J. Mcelwee |
| المصدر: | Diabetic Medicine. 22:92-96 |
| بيانات النشر: | Wiley, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Adult, Insulin pump, medicine.medical_specialty, Pediatrics, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Hypoglycemia, Insulin Infusion Systems, Endocrinology, Quality of life, Diabetes management, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Insulin, Child, Glycated Hemoglobin, Coma, Type 1 diabetes, business.industry, Infant, medicine.disease, Surgery, Diabetes Mellitus, Type 1, Treatment Outcome, Child, Preschool, Quality of Life, medicine.symptom, business |
| الوصف: | Aims To determine the impact of insulin pump therapy (continuous subcutaneous insulin infusion) on key parameters of diabetes management including quality of life in children and adolescents with Type 1 diabetes mellitus (T1DM). Methods All patients started on insulin pump therapy were prospectively followed before and after institution of insulin pump therapy. Data collected included age, duration of diabetes, glycated haemoglobin levels (HbA1c), anthropometric data and episodes of severe hypoglycaemia defined as hypoglycaemia resulting in coma or convulsion. A subset of patients also completed the Diabetes Quality of Life Instrument (DQOL) and Self-Efficacy for Diabetes Scale (SED) questionnaires to assess quality of life. Results At the time of analysis, 100 patients had been managed with insulin pump therapy. The mean age when starting pump therapy was 12.5 (3.9–19.6) years. Duration of therapy ranged from 0.2 to 4.0 years (mean 1.4 years, median 1.5 years). HbA1c decreased from 8.3 ± 0.1% prior to pump therapy to 7.8 ± 0.1% (P < 0.0001). Episodes of severe hypoglycaemia decreased from 32.9 to 11.4 per 100 patient years. Components of quality of life measures showed improvement on pump treatment. BMI standard deviation scores (z scores) did not increase. Conclusions Pump therapy is proving an effective means of insulin therapy in the young patient that shows promise to improve glycaemic control with a reduction in hypoglycaemia frequency. Quality of Life measures suggest that psychosocial outcomes may be improved. |
| تدمد: | 1464-5491 0742-3071 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012b084530086a14cbff1b9a6419dac2Test https://doi.org/10.1111/j.1464-5491.2004.01359.xTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....012b084530086a14cbff1b9a6419dac2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14645491 07423071 |
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