نتائج البحث - "Eyermann, C.J."

1

دورية أكاديمية

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

المؤلفون: Jansen, J., Reimer, K.C., Nagai, J.S., Varghese, F.S., Overheul, G.J., de Beer, M., Roverts, R., Daviran, D., Fermin, L.A.S., Willemsen, B., Beukenboom, M., Djudjaj, S., von Stillfried, S., van Eijk, L.E., Mastik, M., Bulthuis, M., Dunnen, W.D., van Goor, H., Hillebrands, J.-L., Triana, S.H., Alexandrov, T., Timm, M.-C., van den Berge, B.T., van den Broek, M., Nlandu, Q., Heijnert, J., Bindels, E.M.J., Hoogenboezem, R.M., Mooren, F., Kuppe, C., Miesen, P., Grünberg, K., Ijzermans, T., Steenbergen, E.J., Czogalla, J., Schreuder, M.F., Sommerdijk, N., Akiva, A., Boor, P., Puelles, V.G., Floege, J., Huber, T.B., van Rij, R.P., Costa, I.G., Schneider, R.K., Smeets, B., Kramann, R., Achdout, H., Aimon, A., Bar-David, E., Barr, H., Ben-Shmuel, A., Bennett, J., Boby, M.L., Borden, B., Bowman, G.R., Brun, J., BVNBS, S., Calmiano, M., Carbery, A., Cattermole, E., Chernychenko, E., Choder, J.D., Clyde, A., Coffland, J.E., Cohen, G., Cole, J., Contini, A., Cox, L., Cvitkovic, M., Dias, A., Donckers, K., Dotson, D.L., Douangamath, A., Duberstein, S., Dudgeon, T., Dunnett, L., Eastman, P.K., Erez, N., Eyermann, C.J., Fairhead, M., Fate, G., Fearon, D., Federov, O., Ferla, M., Fernandes, R.S., Ferrins, L., Foster, R., Foster, H., Gabizon, R., Garcia-Sastre, A., Gawriljuk, V.O., Gehrtz, P., Gileadi, C., Giroud, C., Glass, W.G., Glen, R., Itai glinert, Godoy, A.S., Gorichko, M., Gorrie-Stone, T., Griffen, E.J., Hart, S.H., Heer, J., Henry, M., Hill, M., Horrell, S., Hurley, M.F.D., Israely, T., Jajack, A., Jnoff, E., Jochmans, D., John, T., De Jonghe, S., Kantsadi, A.L., Kenny, P.W., Kiappes, J.L., Koekemoer, L., Kovar, B., Krojer, T., Lee, A.A., Lefker, B.A., Levy, H., London, N., Lukacik, P., Macdonald, H.B., Maclean, B., Malla, T.R., Matviiuk, T., McCorkindale, W., McGovern, B.L., Melamed, S., Michurin, O., Mikolajek, H., Milne, B.F., Morris, A., Morris, G.M., Morwitzer, M.J., Moustakas, D., Nakamura, A.M., Neto, J.B., Neyts, J., Nguyen, L., Noske, G.D., Oleinikovas, V., Oliva, G., Owen, D., Psenak, V., Pai, R., Pan, J., Paran, N., Perry, B., Pingle, M., Pinjari, J., Politi, B., Powell, A., Puni, R., Rangel, V.L., Reddi, R.N., Reid, S.P., Resnick, E., Ripka, E.G., Robinson, M.C., Robinson, R.P., Rodriguez-Guerra, J., Rosales, R., Rufa, D., Schofield, C., Shafeev, M., Shaikh, A., Shi, J., Shurrush, K., Sing, S., Sittner, A., Skyner, R., Smalley, A., Smilova, M.D., Solmesky, L.J., Spencer, J., Strain-Damarell, C., Swamy, V., Tamir, H., Tennant, R., Thompson, W., Thompson, A., Tomasia, S., Tumber, A., Vakonakis, I., van Geel, L., Vaschetto, M., Vitner, E.B., Voelz, V., Volkamer, A., von Delft, F., von Delft, A., Walsh, M., Ward, W., Weatherall, C., Weiss, S., White, K.M., Wild, C.F., Wittmann, M., Wright, N., Yahalom-Ronen, Y., Zaidmann, D., Zidane, H., Zitzmann, N.

وصف الملف: text

العلاقة: https://eprints.whiterose.ac.uk/211975/1/PIIS1934590921005208.pdfTest; Jansen, J. orcid.org/0000-0003-0513-6102 , Reimer, K.C. orcid.org/0000-0002-7118-9133 , Nagai, J.S. orcid.org/0000-0002-7655-7206 et al. (208 more authors) (2022) SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids. Cell Stem Cell, 29 (2). 217-231.e8. ISSN 1934-5909

الإتاحة: https://eprints.whiterose.ac.uk/211975Test/
https://eprints.whiterose.ac.uk/211975/1/PIIS1934590921005208.pdfTest

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2

دورية أكاديمية

Antitubercular 2‑pyrazolylpyrimidinones: Structure−activity relationship and mode-of-action studies

المساهمون: Vinayak Singh, Frederick A. Sirgel, Paul D. van Helden: South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa

مصطلحات موضوعية: Bacterial proteins, Animals, Iron, Mycobacterium tuberculosis, Membrane transport proteins, SDG-03 Good health and well-being

وصف الملف: application/pdf

العلاقة: Soares de Melo C, Singh V, Myrick A, Simelane SB, Taylor D, Brunschwig C, Lawrence N, Schnappinger D, Engelhart CA, Kumar A, Parish T, Su Q, Myers TG, Boshoff HIM, Barry CE 3rd, Sirgel FA, van Helden PD, Buchanan KI, Bayliss T, Green SR, Ray PC, Wyatt PG, Basarab GS, Eyermann CJ, Chibale K, Ghorpade SR. Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies. J. Med. Chem. 2021, 64, 1, 719–740. doi:10.1021/acs.jmedchem.0c01727; Journanl of Medicinal Chemistry; https://hdl.handle.net/11288/595935Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.0c01727Test
https://hdl.handle.net/11288/595935Test

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3

دورية أكاديمية

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.

المؤلفون: Boby, M.L., Fearon, D., Ferla, M., Filep, M., Koekemoer, L., Robinson, M.C., Chodera, J.D., Lee, A.A., London, N., Delft, A. von, Delft, F. von, Achdout, H., Aimon, A., Alonzi, D.S., Arbon, R., Aschenbrenner, J.C., Balcomb, B.H., Bar-David, E., Barr, H., Ben-Shmuel, A., Bennett, J., Bilenko, V.A., Borden, B., Boulet, P., Bowman, G.R., Brewitz, L., Brun, J., Bvnbs, S., Calmiano, M., Carbery, A., Carney, D.W., Cattermole, E., Chang, E., Chernyshenko, E., Clyde, A., Coffland, J.E., Cohen, G., Cole, J.C., Contini, A., Cox, L., Croll, T.I., Cvitkovic, M., Jonghe, S. De, Dias, A., Donckers, K., Dotson, D.L., Douangamath, A., Duberstein, S., Dudgeon, T., Dunnett, L.E., Eastman, P., Erez, N., Eyermann, C.J., Fairhead, M., Fate, G., Fedorov, O., Fernandes, R.S., Ferrins, L., Foster, R., Foster, H., Fraisse, L., Gabizon, R., García-Sastre, A., Gawriljuk, V.O., Gehrtz, P., Gileadi, C., Giroud, C., Glass, W.G., Glen, R.C., Glinert, I., Godoy, A.S., Gorichko, M., Gorrie-Stone, T., Griffen, E.J., Haneef, A., Hassell Hart, S, Heer, J., Henry, M., Hill, M., Horrell, S., Huang, Q.Y.J., Huliak, V.D., Hurley, M.F.D., Israely, T., Jajack, A., Jansen, J, Jnoff, E., Jochmans, D., John, T., Kaminow, B., Kang, L., Kantsadi, A.L., Kenny, P.W., Kiappes, J.L., Kinakh, S.O., Kovar, B., Krojer, T., La, V.N.T., Laghnimi-Hahn, S., Lefker, B.A., Levy, H., Lithgo, R.M., Logvinenko, I.G., Lukacik, P., Macdonald, H.B., MacLean, E.M., Makower, L.L., Malla, T.R., Marples, P.G., Matviiuk, T., McCorkindale, W., McGovern, B.L., Melamed, S., Melnykov, K.P., Michurin, O., Miesen, P., Mikolajek, H., Milne, B.F., Minh, D., Morris, A., Morris, G.M., Morwitzer, M.J., Moustakas, D., Mowbray, C.E., Nakamura, A.M., Neto, J.B., Neyts, J., Nguyen, L, Noske, G.D., Oleinikovas, V., Oliva, G., Overheul, G.J., Owen, C.D., Pai, R., Pan, J., Paran, N., Payne, A.M., Perry, B., Pingle, M., Pinjari, J., Politi, B., Powell, A., Pšenák, V., Pulido, I., Puni, R., Rangel, V.L., Reddi, R.N., Rees, P., Reid, S.P., Reid, L., Resnick, E., Ripka, E.G., Robinson, R.P., Rodriguez-Guerra, J., Rosales, R., Rufa, D.A., Saar, K., Saikatendu, K.S., Salah, E., Schaller, D., Scheen, J., Schiffer, C.A., Schofield, C.J., Shafeev, M., Shaikh, A., Shaqra, A.M., Shi, J., Shurrush, K., Singh, S., Sittner, A., Sjö, P., Skyner, R., Smalley, A., Smeets, B., Smilova, M.D., Solmesky, L.J., Spencer, J., Strain-Damerell, C., Swamy, V., Tamir, H., Taylor, J.C., Tennant, R.E., Thompson, W., Thompson, A., Tomásio, S., Tomlinson, C.W.E., Tsurupa, I.S., Tumber, A., Vakonakis, I., Rij, R.P. van, Vangeel, L., Varghese, F.S., Vaschetto, M., Vitner, E.B., Voelz, V., Volkamer, A., Walsh, M.A., Ward, W., Weatherall, C., Weiss, S., White, K.M., Wild, C.F., Witt, K.D., Wittmann, M., Wright, N., Yahalom-Ronen, Y., Yilmaz, N.K., Zaidmann, D., Zhang, I., Zidane, H., Zitzmann, N., Zvornicanin, S.N.

المصدر: Science, 382, 6671, pp. eabo7201

مصطلحات موضوعية: All institutes and research themes of the Radboud University Medical Center, Radboudumc 11: Renal disorders Pathology, Radboudumc 4: lnfectious Diseases and Global Health Medical Microbiology

العلاقة: https://repository.ubn.ru.nl/handle/2066/300172Test

الإتاحة: https://doi.org/10.1126/science.abo7201Test
https://repository.ubn.ru.nl/handle/2066/300172Test

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4

دورية أكاديمية

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

المؤلفون: Boby, M.L., Fearon, D., Ferla, M., Filep, M., Koekemoer, L., Robinson, M.C., Chodera, J.D., Lee, A.A., London, N., von Delft, A., von Delft, F., Achdout, H., Aimon, A., Alonzi, D.S., Arbon, R., Aschenbrenner, J.C., Balcomb, B.H., Bar-David, E., Barr, H., Ben-Shmuel, A., Bennett, J., Bilenko, V.A., Borden, B., Boulet, P., Bowman, G.R., Brewitz, L., Brun, J., BVNBS, S., Calmiano, M., Carbery, A., Carney, D.W., Cattermole, E., Chang, E., Chernyshenko, E., Clyde, A., Coffland, J.E., Cohen, G., Cole, J.C., Contini, A., Cox, L., Croll, T.I., Cvitkovic, M., De Jonghe, S., Dias, A., Donckers, K., Dotson, D.L., Douangamath, A., Duberstein, S., Dudgeon, T., Dunnett, L.E., Eastman, P., Erez, N., Eyermann, C.J., Fairhead, M., Fate, G., Fedorov, O., Fernandes, R.S., Ferrins, L., Foster, R., Foster, H., Fraisse, L., Gabizon, R., García-Sastre, A., Gawriljuk, V.O., Gehrtz, P., Gileadi, C., Giroud, C., Glass, W.G., Glen, R.C., Glinert, I., Godoy, A.S., Gorichko, M., Gorrie-Stone, T., Griffen, E.J., Haneef, A., Hassell Hart, S., Heer, J., Henry, M., Hill, M., Horrell, S., Huang, Q.Y.J., Huliak, V.D., Hurley, M.F.D., Israely, T., Jajack, A., Jansen, J., Jnoff, E., Jochmans, D., John, T., Kaminow, B., Kang, L., Kantsadi, A.L., Kenny, P.W., Kiappes, J.L., Kinakh, S.O., Kovar, B., Krojer, T., La, V.N.T., Laghnimi-Hahn, S., Lefker, B.A., Levy, H., Lithgo, R.M., Logvinenko, I.G., Lukacik, P., Macdonald, H.B., MacLean, E.M., Makower, L.L., Malla, T.R., Marples, P.G., Matviiuk, T., McCorkindale, W., McGovern, B.L., Melamed, S., Melnykov, K.P., Michurin, O., Miesen, P., Mikolajek, H., Milne, B.F., Minh, D., Morris, A., Morris, G.M., Morwitzer, M.J., Moustakas, D., Mowbray, C.E., Nakamura, A.M., Neto, J.B., Neyts, J., Nguyen, L., Noske, G.D., Oleinikovas, V., Oliva, G., Overheul, G.J., Owen, C.D., Pai, R., Pan, J., Paran, N., Payne, A.M., Perry, B., Pingle, M., Pinjari, J., Politi, B., Powell, A., Pšenák, V., Pulido, I., Puni, R., Rangel, V.L., Reddi, R.N., Rees, P., Reid, S.P., Reid, L., Resnick, E., Ripka, E.G., Robinson, R.P., Rodriguez-Guerra, J., Rosales, R., Rufa, D.A., Saar, K., Saikatendu, K.S., Salah, E., Schaller, D., Scheen, J., Schiffer, C.A., Schofield, C.J., Shafeev, M., Shaikh, A., Shaqra, A.M., Shi, J., Shurrush, K., Singh, S., Sittner, A., Sjö, P., Skyner, R., Smalley, A., Smeets, B., Smilova, M.D., Solmesky, L.J., Spencer, J., Strain-Damerell, C., Swamy, V., Tamir, H., Taylor, J.C., Tennant, R.E., Thompson, W., Thompson, A., Tomásio, S., Tomlinson, C.W.E., Tsurupa, I.S., Tumber, A., Vakonakis, I., van Rij, R.P., Vangeel, L., Varghese, F.S., Vaschetto, M., Vitner, E.B., Voelz, V., Volkamer, A., Walsh, M.A., Ward, W., Weatherall, C., Weiss, S., White, K.M., Wild, C.F., Witt, K.D., Wittmann, M., Wright, N., Yahalom-Ronen, Y., Yilmaz, N.K., Zaidmann, D., Zhang, I., Zidane, H., Zitzmann, N., Zvornicanin, S.N.

العلاقة: Boby, M.L., Fearon, D. orcid.org/0000-0003-3529-7863 , Ferla, M. et al. (209 more authors) (2023) Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382 (6671). eabo7201. ISSN 0036-8075

الإتاحة: https://eprints.whiterose.ac.uk/209332Test/

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5

دورية أكاديمية

Preclinical characterization of CNS-active, mutant-selective fourth-generation EGFR inhibitors with potent activity against single, double, and triple mutant EGFR variants including T790M and C797S

المؤلفون: Zhang, S., Huang, W.S., Nadworny, S., Ye, E., Narasimhan, N., Eyermann, C.J., Dalgarno, D., Rivera, V., Shakespeare, W.

المصدر: European Journal of Cancer ; volume 174, page S85 ; ISSN 0959-8049

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/s0959-8049Test(22)01024-3
https://api.elsevier.com/content/article/PII:S0959804922010243?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0959804922010243?httpAccept=text/plainTest

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6

دورية أكاديمية

Orientation of oxazolidinones in the active site of monoamine oxidase

المؤلفون: Jones, T.Z.E., Fleming, P., Eyermann, C.J., Gravestock, M.B., Ramsay, Rona Ruth

المصدر: Jones , T Z E , Fleming , P , Eyermann , C J , Gravestock , M B & Ramsay , R R 2005 , ' Orientation of oxazolidinones in the active site of monoamine oxidase ' , Biochemical Pharmacology , vol. 70 , no. 3 , pp. 407-416 . https://doi.org/10.1016/j.bcp.2005.05.001Test

مصطلحات موضوعية: oxazolidinone, monoamine oxidase, difference spectra, flexible docking, kinetics, ANTIBACTERIAL AGENTS, INHIBITORS ALTER, B INACTIVATORS, DERIVATIVES, TYRAMINE

العلاقة: https://research-portal.st-andrews.ac.uk/en/researchoutput/orientation-of-oxazolidinones-in-the-active-site-of-monoamine-oxidaseTest(b84bba2e-b9bd-4029-b40e-f4b4eb087cbe).html

الإتاحة: https://doi.org/10.1016/j.bcp.2005.05.001Test
https://research-portal.st-andrews.ac.uk/en/researchoutput/orientation-of-oxazolidinones-in-the-active-site-of-monoamine-oxidaseTest(b84bba2e-b9bd-4029-b40e-f4b4eb087cbe).html

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7

دورية أكاديمية

Orientation of oxazolidinones in the active site of monoamine oxidase

المؤلفون: Jones, T.Z.E., Fleming, P., Eyermann, C.J., Gravestock, M.B., Ramsay, Rona Ruth

المصدر: Jones , T Z E , Fleming , P , Eyermann , C J , Gravestock , M B & Ramsay , R R 2005 , ' Orientation of oxazolidinones in the active site of monoamine oxidase ' , Biochemical Pharmacology , vol. 70 , no. 3 , pp. 407-416 . https://doi.org/10.1016/j.bcp.2005.05.001Test

مصطلحات موضوعية: oxazolidinone, monoamine oxidase, difference spectra, flexible docking, kinetics, ANTIBACTERIAL AGENTS, INHIBITORS ALTER, B INACTIVATORS, DERIVATIVES, TYRAMINE

الإتاحة: https://doi.org/10.1016/j.bcp.2005.05.001Test
https://risweb.st-andrews.ac.uk/portal/en/researchoutput/orientation-of-oxazolidinones-in-the-active-site-of-monoamine-oxidaseTest(b84bba2e-b9bd-4029-b40e-f4b4eb087cbe).html

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8

دورية أكاديمية

Orientation of oxazolidinones in the active site of monoamine oxidase

المؤلفون: Jones, T.Z.E., Fleming, P., Eyermann, C.J., Gravestock, M.B., Ramsay, Rona Ruth

المصدر: Jones , T Z E , Fleming , P , Eyermann , C J , Gravestock , M B & Ramsay , R R 2005 , ' Orientation of oxazolidinones in the active site of monoamine oxidase ' , Biochemical Pharmacology , vol. 70 , no. 3 , pp. 407-416 . https://doi.org/10.1016/j.bcp.2005.05.001Test

مصطلحات موضوعية: oxazolidinone, monoamine oxidase, difference spectra, flexible docking, kinetics, ANTIBACTERIAL AGENTS, INHIBITORS ALTER, B INACTIVATORS, DERIVATIVES, TYRAMINE