Early intervention and neurodevelopmental outcome of infants with posthemorrhagic hydrocephalus: A case series and literature review

التفاصيل البيبلوغرافية
العنوان: Early intervention and neurodevelopmental outcome of infants with posthemorrhagic hydrocephalus: A case series and literature review
المؤلفون: Eva Chavana Naranjo, Paola Valdez-Sandoval, Pilar Robles-Lomelin, Yazmin Lemus Rodriguez, Silvia León Cortés, Paola M. Garnica Vazquez, Carlos Perez-Vega, Victor Garcia-Navarro
المصدر: Clinical neurology and neurosurgery. 201
سنة النشر: 2020
مصطلحات موضوعية: Male, Pediatrics, medicine.medical_specialty, Psychological intervention, 03 medical and health sciences, 0302 clinical medicine, Corrected Age, Posthemorrhagic hydrocephalus, Intervention (counseling), medicine, Humans, In patient, Ventricular dilation, Cerebral Hemorrhage, Retrospective Studies, business.industry, Infant, Newborn, Infant, General Medicine, medicine.disease, Cerebrospinal Fluid Shunts, Clinical trial, Intraventricular hemorrhage, Neurodevelopmental Disorders, 030220 oncology & carcinogenesis, Surgery, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, Infant, Premature, Hydrocephalus
الوصف: Objective Intraventricular hemorrhage (IVH) is the most common central nervous system pathology in preterm infants. No consensus has been reached over the best indication for intervention in patients with posthemorrhagic hydrocephalus (PHH). The authors present the neurological outcome of infants with IVH and an early treatment approach, defined as an intervention when ventricular dilation is less than 4-mm over the 97th-percentile of Levene’s index. Methods We performed a retrospective case-series study of 12 infants who had IVH and an early intervention, their neurological development was evaluated after 18-months of corrected age using the Bayley-III Scales. Measures of central tendency and Pearson’s correlation were used for data analysis. Results In a 15-month period, twelve patients were diagnosed with IVH and underwent an early intervention. At the time of diagnosis, 2 patients had grade II IVH, 7 grade III, and 3 grade IV. Subgaleal shunt was the first intervention. 9 (75 %) ultimately required a ventriculoperitoneal shunt. A total of 9 (75 %) patients had normal cognitive scores, 7 (58.3 %) for the language-composite, and 8 (66.7 %) for the motor-composite. 6 (50 %) patients had normal scores in all composites. The average scores reported normal results (CC:98.33 ± 22.59; LC:98.25 ± 23.93; MC:88.58 ± 21.47). There was a significant correlation between antenatal steroids and the LC-score (p = 0.044). Conclusions Half of the patients with PHH and early neurosurgical interventions had an average or above average neurodevelopmental score in all three areas. Current literature and undergoing clinical trials have shown promising results on the implementation of this type of intervention.
تدمد: 1872-6968
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3eff1a6cac7b092cd762f223ed1c97Test
https://pubmed.ncbi.nlm.nih.gov/33383466Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....8f3eff1a6cac7b092cd762f223ed1c97
قاعدة البيانات: OpenAIRE