المؤلفون: Matthew A. Coelho, Etienne De Braekeleer, Mike Firth, Michal Bista, Sebastian Lukasiak, Maria Emanuela Cuomo, Benjamin J. M. Taylor

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/5ca3e3c9d50c40859d3cc5b4b7665184Test

المؤلفون: Konstantinos Tzelepis, Etienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M. S. Vijayabaskar, Wen-Hsin Liu, Malgorzata Gozdecka, Emmanouil Metzakopian, Hamish D. Toop, Monika Dudek, Samuel C. Robson, Francisco Hermida-Prado, Yu Hsuen Yang, Roya Babaei-Jadidi, Dimitrios A. Garyfallos, Hannes Ponstingl, Joao M. L. Dias, Paolo Gallipoli, Michael Seiler, Silvia Buonamici, Binje Vick, Andrew J. Bannister, Roland Rad, Rab K. Prinjha, John C. Marioni, Brian Huntly, Jennifer Batson, Jonathan C. Morris, Cristina Pina, Allan Bradley, Irmela Jeremias, David O. Bates, Kosuke Yusa, Tony Kouzarides, George S. Vassiliou

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/1853a1ced0ff46dfaf75bec9896c8581Test

المؤلفون: Konstantinos Tzelepis, Hiroko Koike-Yusa, Etienne De Braekeleer, Yilong Li, Emmanouil Metzakopian, Oliver M. Dovey, Annalisa Mupo, Vera Grinkevich, Meng Li, Milena Mazan, Malgorzata Gozdecka, Shuhei Ohnishi, Jonathan Cooper, Miten Patel, Thomas McKerrell, Bin Chen, Ana Filipa Domingues, Paolo Gallipoli, Sarah Teichmann, Hannes Ponstingl, Ultan McDermott, Julio Saez-Rodriguez, Brian J.P. Huntly, Francesco Iorio, Cristina Pina, George S. Vassiliou, Kosuke Yusa

المصدر: Cell Reports, Vol 17, Iss 4, Pp 1193-1205 (2016)

مصطلحات موضوعية: CRISPR, genetic screen, genetic vulnerability, acute myeloid leukemia, AML, KAT2A, MB-3, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124716313353Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/c8faecf711f04641b78d953688cead72Test

المؤلفون: Jacob Insua‐Rodríguez, Maren Pein, Tsunaki Hongu, Jasmin Meier, Arnaud Descot, Camille M Lowy, Etienne De Braekeleer, Hans‐Peter Sinn, Saskia Spaich, Marc Sütterlin, Andreas Schneeweiss, Thordur Oskarsson

المصدر: EMBO Molecular Medicine, Vol 10, Iss 10, Pp n/a-n/a (2018)

مصطلحات موضوعية: breast cancer metastasis, chemotherapy resistance, extracellular matrix, stem cell niche, stress, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1757-4676Test; https://doaj.org/toc/1757-4684Test

الوصول الحر: https://doaj.org/article/b247d332148a419e955b465ec8e5f91cTest

المؤلفون: Suruchi Pacharne, Jonathan L. Cooper, Hannes Ponstingl, Malgorzata Gozdecka, Mathias J Friedrich, George S. Vassiliou, Penny Wright, Grace Collord, Maxim Barenboim, M S Vijayabaskar, Milena Mazan, Sandeep S Rajan, Roland Rad, Muxin Gu, Konstantinos Tzelepis, Oliver M. Dovey, Ruben Bautista, Etienne De Braekeleer

المصدر: Blood Adv

مصطلحات موضوعية: NPM1, Biology, medicine.disease_cause, Fusion gene, Insertional mutagenesis, Mice, chemistry.chemical_compound, hemic and lymphatic diseases, CEBPA, medicine, Animals, neoplasms, Mutation, Myeloid Neoplasia, Nuclear Proteins, Myeloid leukemia, Histone-Lysine N-Methyltransferase, Hematology, medicine.disease, body regions, DNA-Binding Proteins, Leukemia, Myeloid, Acute, Leukemia, RUNX1, chemistry, embryonic structures, Acute Disease, Cancer research, Nucleophosmin, psychological phenomena and processes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415c0a4abfd0e52ba45e476469350872Test
https://doi.org/10.1182/bloodadvances.2020003443Test

المؤلفون: Yusuke Tarumoto, Jonathan L. Cooper, Brian J. P. Huntly, George S. Vassiliou, Konstantinos Tzelepis, Xi Chen, Malgorzata Gozdecka, Demetrios Aspris, Muxin Gu, Etienne De Braekeleer, Kosuke Yusa, Jason S. L. Yu, Yan Zi Au, Swee Hoe Ong

المساهمون: Gu, Muxin [0000-0003-4376-795X], Tzelepis, Konstantinos [0000-0002-4865-7648], Huntly, Brian [0000-0003-0312-161X], Vassiliou, George [0000-0003-4337-8022], Apollo - University of Cambridge Repository

المصدر: Leukemia

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, BRD4, Lysine Acetyltransferases, Oncogene Proteins, Fusion, Apoptosis, Biology, Article, Epigenesis, Genetic, Histones, 03 medical and health sciences, Gene Knockout Techniques, 0302 clinical medicine, Cancer epigenetics, hemic and lymphatic diseases, Cell Line, Tumor, Transcriptional regulation, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, Myeloid Cells, KAT7, Promoter Regions, Genetic, neoplasms, Genetic Association Studies, Histone Acetyltransferases, Gene Rearrangement, Cancer stem cells, Myeloid leukemia, Disease Management, Cell Differentiation, Hematology, Histone-Lysine N-Methyltransferase, 3. Good health, Leukemia, Myeloid, Acute, 030104 developmental biology, Histone, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Myeloid-Lymphoid Leukemia Protein, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1f83a1b5c13994528ef8f7c7e96e47Test
http://europepmc.org/articles/PMC7610570Test

المؤلفون: Esteban A. Orellana, Eric S. Fischer, Mehdi Pirouz, Demetrios Aspris, Jihoon Lim, George S. Vassiliou, Konstantinos Tzelepis, Richard I. Gregory, Etienne De Braekeleer, Gonçalo J. L. Bernardes, Qi Liu, Alejandro Gutierrez, Erdem Sendinc, Muxin Gu, Sigitas Mikutis, Frank J. Slack, Wen Cai Zhang, Eliza Yankova, Allan Bradley, Raja Hussain Ali, Dimitrios A. Garyfallos

المصدر: Mol Cell

مصطلحات موضوعية: TRNA modification, Methyltransferase, Cell, RNA, Translation (biology), Cell Biology, Biology, Cell cycle, Article, Cell biology, medicine.anatomical_structure, RNA, Transfer, GTP-Binding Proteins, Epitranscriptomics, Neoplasms, Transfer RNA, medicine, Humans, RNA, Messenger, RNA Processing, Post-Transcriptional, Molecular Biology, Ribosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e86d4daac3626d82c187ece2288d8daTest
https://europepmc.org/articles/PMC8380730Test/

المؤلفون: Malgorzata Gozdecka, Eshwar Meduri, Milena Mazan, Konstantinos Tzelepis, Monika Dudek, Andrew J. Knights, Mercedes Pardo, Lu Yu, Jyoti S. Choudhary, Emmanouil Metzakopian, Vivek Iyer, Haiyang Yun, Naomi Park, Ignacio Varela, Ruben Bautista, Grace Collord, Oliver Dovey, Dimitrios A. Garyfallos, Etienne De Braekeleer, Saki Kondo, Jonathan Cooper, Berthold Göttgens, Lars Bullinger, Paul A. Northcott, David Adams, George S. Vassiliou, Brian J. P. Huntly

المصدر: Nature Genetics. 54:1062-1062

مصطلحات موضوعية: Genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1c5ca19f3c4b610e39f3b6806ba5bfb9Test
https://doi.org/10.1038/s41588-022-01060-9Test

المؤلفون: Etienne De Braekeleer, Patrick Guest, Maria Eleftheriou, Georgia Tsagkogeorga, Ewa S. Pilka, Nerea Irigoyen, Malgorzata Gozdecka, Tony Kouzarides, Binje Vick, Andrew J. Bannister, Richard Fosbeary, Mark Albertella, Justyna Rak, Alan G. Hendrick, Irmela Jeremias, Dan Leggate, Demetrios Aspris, George S. Vassiliou, Eliza Yankova, Oliver Rausch, Natalie A. Webster, Konstantinos Tzelepis, Byron Andrews, João Lopes Dias, Wesley Blackaby

المساهمون: Yankova, Eliza [0000-0003-2913-0012], Pilka, Ewa S [0000-0002-0107-2597], Hendrick, Alan G [0000-0002-8604-0462], Irigoyen, Nerea [0000-0001-6346-3369], Dias, Joao ML [0000-0002-8451-3537], Bannister, Andrew J [0000-0002-6312-4436], Vick, Binje [0000-0003-1956-2778], Jeremias, Irmela [0000-0003-1773-7677], Vassiliou, George S [0000-0003-4337-8022], Rausch, Oliver [0000-0003-4074-3848], Tzelepis, Konstantinos [0000-0002-4865-7648], Kouzarides, Tony [0000-0002-8918-4162], Apollo - University of Cambridge Repository

المصدر: Nature 593, 597-601 (2021)
Nature

مصطلحات موضوعية: Methyltransferase, Adenosine, Antineoplastic Agents, Apoptosis, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Cell Line, Tumor, Animals, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, Molecular Structure, Gene Expression Regulation, Leukemic, RNA, Cell Differentiation, Methyltransferases, Small molecule, Xenograft Model Antitumor Assays, 3. Good health, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Enzyme, chemistry, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Stem cell

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d210f07dd025da467c48c4ac96a2015Test
https://push-zb.helmholtz-muenchenTest.de/frontdoor.php?source_opus=61877

المؤلفون: Benjamin J. M. Taylor, Michal Bista, Mike Firth, Matthew A. Coelho, Sebastian Lukasiak, Maria Emanuela Cuomo, Etienne De Braekeleer

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications

مصطلحات موضوعية: CRISPR-Cas9 genome editing, 0301 basic medicine, Science, General Physics and Astronomy, 02 engineering and technology, Computational biology, Genome, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Genome editing, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Guide RNA, lcsh:Science, Gene Editing, Nuclease, Multidisciplinary, biology, Cas9, Targeted Gene Repair, RNA, General Chemistry, 021001 nanoscience & nanotechnology, Targeted gene repair, 030104 developmental biology, Mutagenesis, biology.protein, lcsh:Q, CRISPR-Cas Systems, 0210 nano-technology, RNA, Guide, Kinetoplastida

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e97c8c9cc72e513b7fad69f6242aa1Test
https://doi.org/10.1038/s41467-020-17952-5Test