التفاصيل البيبلوغرافية
| العنوان: |
Efectividad de la primera dosis de vacuna BNT162b2 para prevenir la COVID-19 en personal sanitario |
| المؤلفون: |
Gras Valentí, Paula, Chico Sánchez, Pablo, Algado Sellés, Natividad, Jiménez-Sepúlveda, Natali Juliet, Gómez-Sotero, Isel Lilibeth, Fuster Pérez, Marina, Sánchez Valero, María, Tremiño Sánchez, Laura, Nadal Morante, Verónica, Monerris Palmer, Miranda, Esclapez Martínez, Ana, Moreno de Arcos Fuentes, Elena, Escalada Martín, Irene, Martínez López, Iluminada, Rodríguez Díaz, Juan Carlos, Merino de Lucas, Esperanza, Sánchez Payá, José, Cartagena Llopis, Lidia, Cerezo-Millán, Patricia, Escribano Cañadas, Isabel de las Mercedes |
| المصدر: |
Revista española de salud pública, ISSN 1135-5727, Nº. 95, 2021 |
| سنة النشر: |
2021 |
| المجموعة: |
Dialnet - Portada de revistas (Universidad de La Rioja) |
| مصطلحات موضوعية: |
COVID-19, SARS-CoV-2, Vacuna SARS-CoV-2, Efectividad vacunal, Personal sanitario, Prevención y control de Infecciones, SARSCoV- 2 vaccine, Vaccine effectiveness, Healthcare personnel, Infection prevention and control |
| الوصف: |
Background: A first protective dose of vaccine may allow delaying the second dose in a context of low supply. The objective is to assess the effectiveness of a single dose of vaccine against SARS-CoV-2 (BNT162b2) after twelve days of its administration in healthcare personnel (HCP) of a Health Department. Methods: A case-control study was made. HCP with suspected COVID-19 and HCP close contacts of COVID-19 cases were included between January 27 and February 7, 2021. They were PCR tested for SARS-CoV-2; those with positive PCR were considered cases and those with negative PCR were considered controls. The crude (VE) and adjusted (VEa) vaccine effectiveness to prevent COVID-19 cases and their 95% confidence interval were calculated using the formula VE = (1-Odds ratio) x 100. Results: 268 HCP were included, of which 70 (26.1%) were considered cases and 198 (73.9%) controls. The frequency of vaccine exposure in cases was 55.7% vs. 69.7% in controls (p=0.035). The VEa of the first vaccine dose was 52.6% (95%CI: 1.1-77.3). The VEa in the subgroup of HCP studied for suspected disease was 74.6% (CI95%: 38.4-89.5). Conclusions: One dose of BNT162b2 vaccine against SARS-CoV-2 offers early protection after twelve days of administration. These data could be considered to adapt strategies and consider postponing the second dose in situations of limited vaccine supply in order to achieve the maximum number of people covered with a first dose. ; Fundamentos: Una primera dosis de vacuna protectora permitiría aplazar la segunda dosis en un contexto de suministro escaso. El objetivo de este trabajo fue conocer la efectividad de una dosis de vacuna frente a SARSCoV- 2 (BNT162b2) tras doce días de su administración en personal sanitario (PS) de un Departamento de Salud. Métodos: Se realizó un estudio de casos y controles. Se incluyó a PS con sospecha de COVID-19 y PS que tuvo contactos estrechos con casos de COVID-19 entre el 27 de enero y el 7 de febrero de 2021. Se les realizó una PCR para determinar SARS-CoV-2; aquellos con PCR ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
Spanish; Castilian |
| العلاقة: |
https://dialnet.unirioja.es/servlet/oaiart?codigo=7957691Test; (Revista) ISSN 1135-5727 |
| الإتاحة: |
https://dialnet.unirioja.es/servlet/oaiart?codigo=7957691Test |
| حقوق: |
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| رقم الانضمام: |
edsbas.53E0B9EA |
| قاعدة البيانات: |
BASE |
