المؤلفون: Yue Li, Long Zhao, Xiao-Feng Li

المصدر: Frontiers in Oncology, Vol 11 (2021)

مصطلحات موضوعية: hypoxia, hypoxia-activated prodrugs, tirapazamine, AQ4N, PR-104, EO9, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2021.700407/fullTest; https://doaj.org/toc/2234-943XTest

الوصول الحر: https://doaj.org/article/1b7853fad6d64ad484fc31a37d9046edTest

المؤلفون: Jain, A., Phillips, Roger M., Scally, Andy J., Lenaz, G., Beer, M., Puri, Rajiv

مصطلحات موضوعية: Multiple Recurrent TaT1 Bladder Cancer, Intravesical Apaziquone (EO9), Tumor recurrence rates, Cancer chemotherapy, Cancer drug therapy, Chemotherapy

الإتاحة: http://hdl.handle.net/10454/5677Test

المؤلفون: Puri, Rajiv, Palit, V., Loadman, Paul, Flannigan, G. Michael, Shah, T.K., Choudry, G.A., Basu, Saurajyoti, Double, John A., Lenaz, G., Chawla, S., Beer, M., Kalken, C.V., de Boer, R., Beijnen, J.H., Twelves, Christopher J., Phillips, Roger M.

مصطلحات موضوعية: EO9, Bladder, Carcinoma, Bladder Neoplasms, Transitional Cell

الإتاحة: http://hdl.handle.net/10454/4150Test

المؤلفون: Choudry, Guzanfar A., Hamilton Stewart, P.A., Double, John A., Krul, M.R.L., Naylor, Brian, Flannigan, G. Michael, Shah, Tariq K., Phillips, Roger M.

مصطلحات موضوعية: Bioreductive drugs, EO9, Mitomycin C, Bladder cancer, NQO1

الإتاحة: http://hdl.handle.net/10454/3889Test

المؤلفون: Dirix, L.Y. (Luc), Tonnesen, F. (F.), Cassidy, S.B. (Suzanne), Epelbaum, J. (Jacques), Ten Bokkel Huinink, W.W. (Wim), Pavlidis, N. (N.), Sorio, R. (R.), Gamucci, T. (T.), Wolff, I., Te Velde, A. (A.), Lan, J. (J.), Verweij, J. (Jaap)

المصدر: European Journal of Cancer vol. 32 no. 11, pp. 2019-2022

مصطلحات موضوعية: Breast cancer, Colorectal cancer, EO9, Gastric cancer, Pancreatic cancer, Phase II study, Proteinuria, Renal toxicity

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/67201Test; urn:hdl:1765/67201

الإتاحة: https://doi.org/10.1016/0959-8049Test(96)00226-2
http://repub.eur.nl/pub/67201Test

المؤلفون: Hitoshi ARAI, Masahiko KINUGAWA, Masaji KASAI, Takehiro OGASA

المصدر: Journal of Synthetic Organic Chemistry, Japan. 1999, 57(5):401

المؤلفون: Roger M. Phillips

المصدر: Cancer Chemotherapy and Pharmacology

مصطلحات موضوعية: 0301 basic medicine, PR-104, TH-4000, Cancer Research, RM, EO9, Bioreductive drugs, medicine.medical_treatment, Antineoplastic Agents, Review Article, Biology, Pharmacology, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Delivery Systems, Neoplasms, medicine, Tumor Microenvironment, Cytotoxic T cell, Animals, Humans, Pharmacology (medical), Prodrugs, Hypoxia, TH-302, chemistry.chemical_classification, Chemotherapy, Tumor microenvironment, Hypoxia-activated prodrugs, AQ4N, Prodrug, Hypoxia (medical), Cell Hypoxia, Radiation therapy, Oxygen, 030104 developmental biology, Enzyme, Oncology, chemistry, 030220 oncology & carcinogenesis, Drug Design, medicine.symptom, Tirapazamine, Oxidoreductases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc65b09df4a911605216c6b945fe936cTest
https://eprints.hud.ac.uk/id/eprint/26511/12/PhillipsFiguresMaintext.pdfTest

المؤلفون: Schellens, J. H. M., Dombernowsky, P., Cassidy, J., Epelbaum, R., Dirix, L., Cox, E. H., Wanders, J., Calabresi, F., Paridaens, R., Monfardini, S., Wolff, J., Loos, W. J., Verweij, J., Pavlidis, Nicholas, Hanauske, A. R.

المساهمون: EORTC Early Clinical Studies Grp, Medical Oncology, Erasmus School of Social and Behavioural Sciences, Pavlidis, Nicholas [0000-0002-2195-9961]

المصدر: Anti-cancer drugs: an international journal on anti-cancer agents
Anti-Cancer Drugs, 12, 583-590. Lippincott Williams & Wilkins
Anti-Cancer Drugs

مصطلحات موضوعية: Male, Cancer Research, Indoles, Indoles/*pharmacokinetics, Unclassified drug, Alkylating agent, Drug exposure, Aziridines, Population Dynamics, Pharmacology, Controlled clinical trial, Neoplasms, Antineoplastic agents, 80 and over, Sampling studies, Medicine, Neoplasms/drug therapy/*metabolism, Pharmacology (medical), Prospective Studies, Middle aged, Drug safety, Prospective cohort study, Antineoplastic Agents/*pharmacokinetics, Priority journal, 5 (1 aziridinyl) 3 hydroxymethyl 2 (3 hydroxy 1 propenyl) 1 methyl 4, media_common, Aged, 80 and over, Area under the curve, Population analysis, education.field_of_study, Eo9, Pharmacology. Therapy, Cytotoxic agent, Middle Aged, Phase ii, Algorithm, Clinical trial, Indolequinones, Oncology, Area Under Curve, Toxicity, Drug clearance, Female, Cancer chemotherapy, Human, Adult, Drug, Indoloquinone, Population dynamics, Metabolic Clearance Rate, media_common.quotation_subject, Population, Drug response, Antineoplastic Agents, Major clinical study, Article, Sampling Studies, Bayesian algorithm, Aziridines/*pharmacokinetics, Pharmacokinetics, Humans, Phase 2 clinical trial, Prospective study, Area under curve, education, Aged, Quinone derivative, business.industry, 7 indoledione, Phase 1 clinical trial, Pharmacodynamics, Human medicine, Metabolic clearance rate, business, Controlled study, Prospective studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafb269bf9a88af154380686eafb058bTest
https://doi.org/10.1097/00001813-200108000-00004Test

المؤلفون: Roger M. Phillips, Brian Naylor, P. A. Hamilton Stewart, J. A. Double, Tariq Shah, G. M. Flannigan, G. A. Choudry, John E. Brown, M. R. L. Krul

المصدر: British Journal of Cancer

مصطلحات موضوعية: RM, Cancer Research, Indoles, Aziridines, Urinary Bladder, Antineoplastic Agents, Pharmacology, Substrate Specificity, chemistry.chemical_compound, Quinone Reductases, Pharmacokinetics, medicine, Humans, Apaziquone, bioreductive drugs: EO9, Indolequinones, Bladder cancer, Biological activity, Regular Article, Hydrogen-Ion Concentration, medicine.disease, NAD(P)H Dehydrogenase (Quinone), Immunohistochemistry, Transitional cell carcinoma, Oncology, Biochemistry, chemistry, Urinary Bladder Neoplasms, Drug delivery, NQO1, mitomycin C: bladder cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55ac0a66429153fba0ded4604468ab9Test
http://europepmc.org/articles/PMC2375160Test

المؤلفون: E. Smitskamp-Wilms, H.M. Pinedo, G. Giaccone, Godefridus J. Peters, B.F.A.M. van der Laan

المساهمون: Faculteit Medische Wetenschappen/UMCG, Damage and Repair in Cancer Development and Cancer Treatment (DARE), Man, Biomaterials and Microbes (MBM)

المصدر: British Journal of Cancer
British Jounal of Cancer, 72(4), 917-921. Nature Publishing Group
University of Groningen

مصطلحات موضوعية: EXPRESSION, Cancer Research, EO9, Indoles, Lung Neoplasms, CARCINOMA, TUMOR-CELLS, MITOMYCIN-C, Aziridines, Antineoplastic Agents, METABOLISM, Reductase, REDUCTASE, MECHANISMS, ACTIVATION, CYTOCHROME B5 REDUCTASE, Carcinoma, Non-Small-Cell Lung, Neoplasms, BIOREDUCTIVE AGENTS, NAD(P)H Dehydrogenase (Quinone), DRUGS, Humans, NAD(P)H, Indolequinones, Cytochrome b5 reductase, HEAD AND NECK SQUAMOUS CELL CARCINOMA, chemistry.chemical_classification, biology, Cytochrome c, Mitomycin C, CYTOCHROME P450 REDUCTASE, Cytochrome P450 reductase, Metabolism, Enzyme, Oncology, chemistry, Biochemistry, Colonic Neoplasms, biology.protein, DT-DIAPHORASE, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65f11f6a600631dc5ce876904d76667Test
https://doi.org/10.1038/bjc.1995.433Test