المؤلفون: Gaymard, Alexandre, Picard, Caroline, Vazzoler, Guilhem, Massin, Pascale, Frobert, Emilie, Sabatier, Murielle, Barthelemy, Mendy, Valette, Martine, Ottmann, Michèle, Casalegno, Jean-Sébastien, Lina, Bruno, Escuret, Vanessa

المساهمون: CIC CHU Lyon (inserm), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Hospices Civils de Lyon (HCL), Laboratoire de Ploufragan-Plouzané-Niort ANSES, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Virologie, Immunologie, Parasitologie Avaires et Cunicoles (VIPAC), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Centre National de Référence des virus des infections respiratoires, Laboratoire de Virologie, Institut des Agents Infectieux, Groupement Hospitalier Nord, Hospices Civils de Lyon, This study was supported by internal funding and performed in the field of the global surveillance of the susceptibility of influenza viruses to antiviral agents performed by the WHO and by the NIC (National Influenza Centre) for South of France and supported by the Institut National de Veille Sanitaire (INVS) and Santé Publique France (SPF) in France .

المصدر: ISSN: 1999-4915 ; Viruses ; https://anses.hal.science/anses-04549222Test ; Viruses, 2024, 16 (3), pp.388. ⟨10.3390/v16030388⟩ ; https://www.mdpi.com/1999-4915/16/3/388Test.

مصطلحات موضوعية: influenzaAviruses, group-1 neuraminidases, oseltamivir resistance, H274Y-NA substitution, H275Y-NA substitution, MESH: Amino Acid Substitution Antiviral Agents / pharmacology Drug Resistance, Viral / genetics Enzyme Inhibitors / pharmacology Humans Influenza A Virus, H1N1 Subtype* / genetics Influenza A virus* / genetics Influenza, Human* Neuraminidase / genetics Neuraminidase / metabolism Oseltamivir / pharmacology Reverse Genetics, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38543754; anses-04549222; https://anses.hal.science/anses-04549222Test; https://anses.hal.science/anses-04549222/documentTest; https://anses.hal.science/anses-04549222/file/viruses-16-00388.pdfTest; PUBMED: 38543754; PUBMEDCENTRAL: PMC10975200

الإتاحة: https://doi.org/10.3390/v16030388Test
https://anses.hal.science/anses-04549222Test
https://anses.hal.science/anses-04549222/documentTest
https://anses.hal.science/anses-04549222/file/viruses-16-00388.pdfTest

المؤلفون: Désiré, Jérôme, Debbah, Zakaria, Gueyrard, David, Marrot, Jérôme, Blériot, Yves, Kato, Atsushi

المساهمون: Synthèse organique E5 – IC2MP équipe 5 (OrgaSynth), Institut de chimie des milieux et matériaux de Poitiers UMR 7285 (IC2MP Poitiers ), Université de Poitiers = University of Poitiers (UP)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers = University of Poitiers (UP)-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École Supérieure de Chimie Physique Électronique de Lyon (CPE)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), University of Toyama, Department of Hospital Pharmacy, University of Toyama, ANR-18-EURE-0010,INTREE,Poitiers Graduate School on physico-chemical properties of INTerfaces for AeRonautic, Energy and Environment(2018)

المصدر: ISSN: 0008-6215.

مصطلحات موضوعية: iminosugar, glycosidases, glycomimetics, structure-activity relationship, MESH: Enzyme Inhibitors* / chemistry, MESH: Enzyme Inhibitors* / pharmacology, MESH: Glycoside Hydrolases / chemistry, MESH: Glycosides / pharmacology, MESH: Humans, MESH: Imino Sugars* / chemistry, MESH: Imino Sugars* / pharmacology, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37523839; hal-04542506; https://hal.science/hal-04542506Test; https://hal.science/hal-04542506/documentTest; https://hal.science/hal-04542506/file/4_PDFsam_CARB-S-23-00291-1.pdfTest; PUBMED: 37523839

الإتاحة: https://doi.org/10.1016/j.carres.2023.108903Test
https://hal.science/hal-04542506Test
https://hal.science/hal-04542506/documentTest
https://hal.science/hal-04542506/file/4_PDFsam_CARB-S-23-00291-1.pdfTest

المؤلفون: Biniecka, P., Matsumoto, S., Belotti, A., Joussot, J., Bai, J.F., Majjigapu, S.R., Thoueille, P., Spaggiari, D., Desfontaine, V., Piacente, F., Bruzzone, S., Cea, M., Decosterd, L.A., Vogel, P., Nencioni, A., Duchosal, M.A., Nahimana, A.

المصدر: Molecules, vol. 28, no. 4, pp. 1897

مصطلحات موضوعية: Animals, Humans, Mice, Cell Line, Tumor, Cytokines/metabolism, Enzyme Inhibitors/pharmacology, Hematologic Neoplasms/drug therapy, NAD/metabolism, Nicotinamide Phosphoribosyltransferase/antagonists & inhibitors, Reactive Oxygen Species, ATP, NAD, NAMPT inhibitor, PK studies, anticancer, apoptosis, leukemia, lymphoma, multiple myeloma, oxidative stress, vitamin B3

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36838885; info:eu-repo/semantics/altIdentifier/eissn/1420-3049; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_9D877CB69A0A9; https://serval.unil.ch/notice/serval:BIB_9D877CB69A0ATest; urn:issn:1420-3049; https://serval.unil.ch/resource/serval:BIB_9D877CB69A0A.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9D877CB69A0A9Test

الإتاحة: https://doi.org/10.3390/molecules28041897Test
https://serval.unil.ch/notice/serval:BIB_9D877CB69A0ATest
https://serval.unil.ch/resource/serval:BIB_9D877CB69A0A.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9D877CB69A0A9Test

المؤلفون: Fratta, S., Biniecka, P., Moreno-Vargas, A.J., Carmona, A.T., Nahimana, A., Duchosal, M.A., Piacente, F., Bruzzone, S., Caffa, I., Nencioni, A., Robina, I.

المصدر: European journal of medicinal chemistry, vol. 250, pp. 115170

مصطلحات موضوعية: Humans, Nicotinamide Phosphoribosyltransferase/metabolism, NAD/metabolism, Cell Line, Tumor, Cytokines/metabolism, Antineoplastic Agents/pharmacology, Leukemia/metabolism, Structure-Activity Relationship, Hematologic Neoplasms/drug therapy, Enzyme Inhibitors/pharmacology, Cancer, Cyanoguanidines, Cytotoxic agents, Furan, NAD(+), NAMPT inhibitors

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36787658; info:eu-repo/semantics/altIdentifier/eissn/1768-3254; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_FD14B5315A4E9; https://serval.unil.ch/notice/serval:BIB_FD14B5315A4ETest; urn:issn:0223-5234; https://serval.unil.ch/resource/serval:BIB_FD14B5315A4E.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FD14B5315A4E9Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2023.115170Test
https://serval.unil.ch/notice/serval:BIB_FD14B5315A4ETest
https://serval.unil.ch/resource/serval:BIB_FD14B5315A4E.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FD14B5315A4E9Test

المؤلفون: Peleli, Maria, Lyngso, Kristina S., Poulsen, Frantz Rom, Hansen, Pernille B.L., Papapetropoulos, Andreas, Stubbe, Jane

المصدر: Peleli , M , Lyngso , K S , Poulsen , F R , Hansen , P B L , Papapetropoulos , A & Stubbe , J 2023 , ' Inhibition of cystathionine-gamma lyase dampens vasoconstriction in mouse and human intracerebral arterioles ' , Acta Physiologica , vol. 239 , no. 1 , e14021 . https://doi.org/10.1111/apha.14021Test

مصطلحات موضوعية: contractility, cystathionine-gamma lyase, endothelial NO synthase, hydrogen sulfide, intracerebral arterioles, soluble guanylate cyclase, Humans, Mice, Inbred C57BL, Vasoconstriction, Arterioles/drug effects, Enzyme Inhibitors/pharmacology, Hydrogen Sulfide/metabolism, Animals, Cystathionine gamma-Lyase/antagonists & inhibitors

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/9c7b8b86-5935-4ca2-8a39-d0f63ed1c7c1Test

الإتاحة: https://doi.org/10.1111/apha.14021Test
https://portal.findresearcher.sdu.dk/da/publications/9c7b8b86-5935-4ca2-8a39-d0f63ed1c7c1Test
https://findresearcher.sdu.dk/ws/files/239678089/Acta_Physiologica_2023_Peleli.pdfTest

المؤلفون: Lawler, Patrick R., Derde, Lennie P.G., Van De Veerdonk, Frank L., McVerry, Bryan J., Huang, David T., Berry, Lindsay R., Lorenzi, Elizabeth, Van Kimmenade, Roland, Gommans, Frank, Vaduganathan, Muthiah, Leaf, David E., Baron, Rebecca M., Kim, Edy Y., Frankfurter, Claudia, Epelmaņ, Slava, Kwan, Yvonne, Grieve, Richard, O'Neill, Stephen, Sadique, Zia, Puskarich, Michael, Marshall, John C., Higgins, Alisa M., Mouncey, Paul R., Rowan, Kathryn M., Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M., Au, Carly, Beane, Abi, Van Bentum-Puijk, Wilma, Bonten, Marc J.M., Bradbury, Charlotte A., Brunkhorst, Frank M., Burrell, Aidan, Buzgau, Adrian, Buxton, Meredith, Cecconi, Maurizio, Cheng, Allen C., Cove, Matthew, Detry, Michelle A., Estcourt, Lise J., Ezekowitz, Justin, Fitzgerald, Mark, Gattas, David, Godoy, Lucas C., Goossens, Herman, Haniffa, Rashan, Harrison, David A., Hills, Thomas, Horvat, Christopher M., Ichihara, Nao, Lamontagne, Francois, Linstrum, Kelsey M., McAuley, Daniel F., McGlothlin, Anna, McGuinness, Shay P., McQuilten, Zoe, Murthy, Srinivas, Nichol, Alistair D., Owen, David R.J., Parke, Rachael L., Parker, Jane C., Pollock, Katrina M., Reyes, Luis Felipe, Saito, Hiroki, Santos, Marlene S., Saunders, Christina T., Seymour, Christopher W., Shankar-Hari, Manu, Singh, Vanessa, Turgeon, Alexis F., Turner, Anne M., Zarychanski, Ryan, Green, Cameron, Lewis, Roger J., Angus, Derek C., Berry, Scott, Gordon, Anthony C., McArthur, Colin J., Webb, Steve A.

المصدر: Lawler , P R , Derde , L P G , Van De Veerdonk , F L , McVerry , B J , Huang , D T , Berry , L R , Lorenzi , E , Van Kimmenade , R , Gommans , F , Vaduganathan , M , Leaf , D E , Baron , R M , Kim , E Y , Frankfurter , C , Epelmaņ , S , Kwan , Y , Grieve , R , O'Neill , S , Sadique , Z , Puskarich , M , Marshall , J C , Higgins ....

مصطلحات موضوعية: Female, Humans, Male, Middle Aged, Angiotensin Receptor Antagonists/pharmacology, Angiotensin-Converting Enzyme Inhibitors/pharmacology, Bayes Theorem, COVID-19/therapy, Renin-Angiotensin System/drug effects, Hospitalization, COVID-19 Drug Treatment/methods, Critical Illness, Receptors, Chemokine/antagonists & inhibitors, /dk/atira/pure/subjectarea/asjc/2700/2700, name=General Medicine

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/8cae3556-8039-49ea-a414-6da1b5a01052Test

الإتاحة: https://doi.org/10.1001/jama.2023.4480Test
https://pure.qub.ac.uk/en/publications/8cae3556-8039-49ea-a414-6da1b5a01052Test
https://pureadmin.qub.ac.uk/ws/files/445375124/REMAP_CAP_ACE2_RAS_Domain_COVID_19_ACCEPTED_3_9_2023.pdfTest

المؤلفون: Franciosa, Giulia, Olsen, Jesper V

المصدر: Franciosa , G & Olsen , J V 2023 , ' Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors ' , OncoTarget , vol. 14 , pp. 281-283 . https://doi.org/10.18632/oncotarget.28392Test

مصطلحات موضوعية: Humans, Phosphorylation, Cell Line, Tumor, Protein Kinase Inhibitors/pharmacology, Tyrosine, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Enzyme Inhibitors/pharmacology

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.18632/oncotarget.28392Test
https://curis.ku.dk/portal/da/publications/impact-of-shp2-tyrosine-phosphorylation-on-the-development-of-acquired-resistance-to-allosteric-shp2Test-inhibitors(ca2d5b9b-3d94-46d2-9081-c5b372fdd0c6).html
https://curis.ku.dk/ws/files/347114335/oncotarget_v14_28392.pdfTest

المساهمون: Tae-Hyun Yoo, Soon Jun Hong, Sunggyun Kim, Seokjoon Shin, Dong Ki Kim, Jung Pyo Lee, Sang Youb Han, Sangho Lee, Jong Chul Won, Young Sun Kang, Jongha Park, Byoung-Geun Han, Ki-Ryang Na, Kyu Yeon Hur, Yong-Jin Kim, Sungha Park, Park, Sung Ha

مصطلحات موضوعية: Albuminuria / chemically induced, Albuminuria / etiology, Angiotensin Receptor Antagonists / pharmacology, Angiotensin-Converting Enzyme Inhibitors / pharmacology, Antihypertensive Agents / therapeutic use, Blood Pressure, Diabetes Mellitus, Diabetic Nephropathies* / drug therapy, Double-Blind Method, Humans, Hypertension, Losartan / pharmacology, Losartan / therapeutic use, Proteinuria / drug therapy, Proteinuria / etiology, Renal Insufficiency, Chronic* / complications, Chronic* / drug therapy, Diabetic nephropathy, Mortality, Proteinuria, Renal endpoint

العلاقة: HYPERTENSION RESEARCH; J01017; OAK-2022-09124; OAK-2022-09125; https://ir.ymlib.yonsei.ac.kr/handle/22282913/192821Test; https://www.nature.com/articles/s41440-022-01028-6Test; T202205861; HYPERTENSION RESEARCH, Vol.45(12) : 2008-2017, 2022-12

الإتاحة: https://doi.org/10.1038/s41440-022-01028-6Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/192821Test
https://www.nature.com/articles/s41440-022-01028-6Test

المساهمون: Jieon Hwang, Areum Park, Chinwoo Kim, Danbi Yu, Hyungju Byun, Minhee Ku, Jaemoon Yang, Tae Il Kim, Kyu-Sung Jeong, Ki Young Kim, Hyuk Lee, Sang Joon Shin, Ku, Min Hee

مصطلحات موضوعية: Animals, Apoptosis / drug effects, Autophagic Cell Death / drug effects, Autophagy / drug effects, Cell Line, Tumor, Cell Proliferation / drug effects, Cellular Reprogramming / genetics, Colorectal Neoplasms / drug therapy, Colorectal Neoplasms / genetics, Colorectal Neoplasms / pathology, Endoplasmic Reticulum / drug effects, Endoplasmic Reticulum / genetics, Endoplasmic Reticulum Stress / drug effects, Enzyme Inhibitors / pharmacology, Fluorouracil / pharmacology, Glycolysis / drug effects, Humans, Metabolic Networks and Pathways / drug effects, Mice, Protein Serine-Threonine Kinases / antagonists & inhibitors, Protein Serine-Threonine Kinases / genetics, Protein-Tyrosine Kinases / antagonists & inhibitors, Protein-Tyrosine Kinases / genetics, Reactive Oxygen Species / metabolism, Xenograft Model Antitumor Assays, DYRK1A protein, DYRK1B protein, autophagy, colorectal cancer

العلاقة: ANTICANCER RESEARCH; J00188; OAK-2022-00168; https://ir.ymlib.yonsei.ac.kr/handle/22282913/187886Test; https://ar.iiarjournals.org/content/42/1/589.longTest; T202200213; ANTICANCER RESEARCH, Vol.42(1) : 589-598, 2022-01

الإتاحة: https://doi.org/10.21873/anticanres.15516Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187886Test
https://ar.iiarjournals.org/content/42/1/589.longTest

المساهمون: Heungjo Kim, Gyunam Park, Jongsung Hahn, Jaewon Oh, Min Jung Chang, Oh, Jae Won

مصطلحات موضوعية: Angiotensin Receptor Antagonists / pharmacology, Angiotensin Receptor Antagonists / therapeutic use, Angiotensin-Converting Enzyme Inhibitors / pharmacology, Angiotensin-Converting Enzyme Inhibitors / therapeutic use, Antihypertensive Agents / therapeutic use, Glucose, Heart Failure* / drug therapy, Humans, Insulins, Neprilysin, Receptors, Angiotensin, Retrospective Studies

العلاقة: SCIENTIFIC REPORTS; J02646; OAK-2022-03287; https://ir.ymlib.yonsei.ac.kr/handle/22282913/189535Test; T202202917; SCIENTIFIC REPORTS, Vol.12(1) : 9703, 2022-06

الإتاحة: https://doi.org/10.1038/s41598-022-13366-zTest
https://ir.ymlib.yonsei.ac.kr/handle/22282913/189535Test