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1دورية أكاديمية
المؤلفون: Valeriy V. Breder, Liudmila G. Zhukova, Larisa V. Bolotina, Irina A. Demidova, Yaroslav A. Zhulikov, Elena V. Lubennikova, David R. Naskhletashvili, Sergey V. Orlov, Rashida V. Orlova, Ilya S. Romanov, Nikita A. Savelov, Ksenia A. Sarantseva, Alexandra S. Tyulyandina, Mikhail Yu. Fedyanin
المصدر: Современная онкология, Vol 25, Iss 3, Pp 295-300 (2023)
مصطلحات موضوعية: ntrk gene fusions, entrectinib, trk inhibitors, molecular testing in solid tumors, secretory carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
العلاقة: https://modernonco.orscience.ru/1815-1434/article/viewFile/159394/pdfTest; https://doaj.org/toc/1815-1434Test; https://doaj.org/toc/1815-1442Test
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2دورية أكاديمية
المصدر: OncoTargets and Therapy, Vol Volume 16, Pp 1055-1059 (2023)
مصطلحات موضوعية: entrectinib, acute myeloid leukemia, etv6::ntrk3, allogeneic hematopoietic stem cell transplantation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
العلاقة: https://www.dovepress.com/post-hsct-maintenance-treatment-usingTest-entrectinib-for-an-aml-patient-a-peer-reviewed-fulltext-article-OTT; https://doaj.org/toc/1178-6930Test
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3دورية أكاديمية
المؤلفون: Hiromune Sawada, Yuri Taniguchi, Shin Iizuka, Toshiki Ikeda, Masaharu Aga, Yusuke Hamakawa, Kazuhito Miyazaki, Yuki Misumi, Yoko Agemi, Yukiko Nakamura, Koki Maeda, Tsuneo Shimokawa, Hiroaki Okamoto
المصدر: Case Reports in Oncology, Vol 16, Iss 1, Pp 1558-1567 (2023)
مصطلحات موضوعية: entrectinib, ros1, crizotinib, leptomeningeal metastasis, non-small-cell lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Shaheenah Dawood, Zulfaqqar Jaffar Ali
المصدر: Case Reports in Oncology, Vol 16, Iss 1, Pp 1451-1459 (2023)
مصطلحات موضوعية: case report, metastatic melanoma, entrectinib, ntrk3 gene fusion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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5دورية أكاديمية
المؤلفون: Dan Li, Yue Zhu, Jincheng Song, Dafu Yang, Saiqiong Cui, Xin Liu, Le Wang, Jiangyan Zhang, Evenki Pan, Zhaoxia Dai
المصدر: Frontiers in Oncology, Vol 14 (2024)
مصطلحات موضوعية: ALK rearrangement, brigatinib, entrectinib, resistance mutations, ETV6-NTRK3, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fonc.2024.1339511/fullTest; https://doaj.org/toc/2234-943XTest
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6دورية أكاديمية
المؤلفون: Kentaro Ito, Miho Nishio, Kentaro Fujiwara, Yoichi Nishii, Kengo Ushiro, Hiroki Yasui, Osamu Hataji
المصدر: Thoracic Cancer, Vol 14, Iss 25, Pp 2622-2626 (2023)
مصطلحات موضوعية: brain metastasis, entrectinib, ROS‐1 fusion, TP53 mutation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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7دورية أكاديمية
المؤلفون: Zhiwei Cui, Zhen Zhai, De Xie, Lihui Wang, Feiyan Cheng, Siyu Lou, Fan Zou, Rumeng Pan, Shixue Chang, Haoyan Yao, Jing She, Yidan Zhang, Xinyuan Yang
المصدر: Frontiers in Pharmacology, Vol 15 (2024)
مصطلحات موضوعية: NTRK, gene fusion, entrectinib, larotrectinib, FAERS, adverse drug event, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2024.1329409/fullTest; https://doaj.org/toc/1663-9812Test
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8دورية أكاديمية
المؤلفون: E. V. Reutova, K. K. Laktionov, Е. В. Реутова, К. К. Лактионов
المصدر: Meditsinskiy sovet = Medical Council; № 22 (2023); 57-62 ; Медицинский Совет; № 22 (2023); 57-62 ; 2658-5790 ; 2079-701X
مصطلحات موضوعية: энтректиниб, targeted therapy, NTRK1/2/3, ROS1 rearrangements, intracranial response, entrectinib, таргетная терапия, ROS1 перестройки, интракраниальный ответ
وصف الملف: application/pdf
العلاقة: https://www.med-sovet.pro/jour/article/view/7985/7072Test; Davare MA, Henderson JJ, Agarwal A, Wagner JP, Iyer SR, Shah N et al. Rare but recurrent ROS1 fusions resulting from chromosome 6q22 microdeletions are targetable oncogenes in glioma. Clin Cancer Res. 2018;24(24):6471–6482. https://doi.org/10.1158/1078-0432.CCR-18-1052Test.; Saborowski A, Saborowski M, Davare MA, Druker BJ, Klimstra DS, Lowe SW. Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target. Proc Natl Acad Sci USA. 2013;110(48):19513–19518. https://doi.org/10.1073/pnas.1311707110Test.; Neel DS, Allegakoen DV, Olivas V, Mayekar MK, Hemmati G, Chatterjee N et al. Differential subcellular localization regulates oncogenic signaling by ROS1 kinase fusion proteins. Cancer Res. 2019;79(3):546–556. https://doi.org/10.1158/0008-5472.CAN-18-1492Test.; Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM et al. Identifying and targeting ROS1 gene fusions in non-small cell lung cancer. Clin Cancer Res. 2012;18(17):4570–457. https://doi.org/10.1158/1078-0432.CCR-12-0550Test.; Davies KD, Doebele RC. Molecular pathways: ROS1 usion proteins in cancer. Clin Cancer Res. 2013;19(15):4040–4045. https://doi.org/10.1158/1078-0432.CCR-12-2851Test.; Bergethon K, Shaw AT, Ou SH, Katayama R, Lovly CM, McDonald NT et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol. 2012;30(8):863–870. https://doi.org/10.1200/JCO.2011.35.6345Test.; Dugay F, Llamas-Gutierrez F, Gournay M, Medane S, Mazet F, Chiforeanu DC et al. Clinicopathological characteristics of ROS1- and RET-rearranged NSCLC in caucasian patients: Data from a cohort of 713 non-squamous NSCLC lacking KRAS/EGFR/HER2/BRAF/PIK3CA/ALK alterations. Oncotarget. 2017;8(32):53336–53351. https://doi.org/10.18632/oncotarget.18408Test.; Gainor JF, Tseng D, Yoda S, Dagogo-Jack I, Friboulet L, Lin JJ et al. Patterns of Metastatic Spread and Mechanisms of Resistance to Crizotinib in ROS1- Positive Non-Small-Cell Lung Cancer. JCO Precis Oncol. 2017;2017:PO.17.00063. https://doi.org/10.1200/PO.17.00063Test.; Mazières J, Zalcman G, Crinò L, Biondani P, Barlesi F, Filleron T et al. Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: results from the EUROS1 cohort. J Clin Oncol. 2015;33(9):992–999. https://doi.org/10.1200/JCO.2014.58.3302Test.; Patil T, Smith DE, Bunn PA, Aisner DL, Le AT, Hancock M et al. The Incidence of Brain Metastases in Stage IV ROS1-Rearranged Non-Small Cell Lung Cancer and Rate of Central Nervous System Progression on Crizotinib. J Thorac Oncol. 2018;13(11):1717–1726. https://doi.org/10.1016/j.jtho.2018.07.001Test.; Wu YL, Yang JC, Kim DW, Lu S, Zhou J, Seto T et al. Phase II Study of Crizotinib in East Asian Patients With ROS1-Positive Advanced Non-Small-Cell Lung Cancer. J Clin Oncol. 2018;36(14):1405–1411. https://doi.org/10.1200/JCO.2017.75.5587Test.; Shaw AT, Riely GJ, Bang YJ, Kim DW, Camidge DR, Solomon BJ et al. Crizotinib in ROS1-rearranged advanced non-small-cell lung cancer (NSCLC): updated results, including overall survival, from PROFILE 1001. Ann Oncol. 2019;30(7):1121–1126. https://doi.org/10.1093/annonc/mdz131Test.; Michels S, Massutí B, Schildhaus HU, Franklin J, Sebastian M, Felip E et al. Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUROCROSS): A European Phase II Clinical Trial. J Thorac Oncol. 2019;14(7):1266–1276. https://doi.org/10.1016/j.jtho.2019.03.020Test.; Costa DB, Kobayashi S, Pandya SS, Yeo WL, Shen Z, Tan W, Wilner KD. CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib. J Clin Oncol. 2011;29(15):e443–445. https://doi.org/10.1200/JCO.2010.34.1313Test.; Jiang Q, Li M, Li H, Chen L. Entrectinib, a new multi-target inhibitor for cancer therapy. Biomed Pharmacother. 2022;150:112974. https://doi.org/10.1016/j.biopha.2022.112974Test.; Fischer H, Ullah M, de la Cruz CC, Hunsaker T, Senn C, Wirz T et al. Entrectinib, a TRK/ROS1 inhibitor with anti-CNS tumor activity: differentiation from other inhibitors in its class due to weak interaction with P-glycoprotein. Neuro Oncol. 2020;22(6):819–829. https://doi.org/10.1093/neuonc/noaa052Test.; Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15(4):628–639. https://doi.org/10.1158/1535-7163.MCT-15-0758Test.; Menichincheri M, Ardini E, Magnaghi P, Avanzi N, Banfi P, Bossi R et al. Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor. J Med Chem. 2016;59(7):3392–3408. https://doi.org/10.1021/acs.jmedchem.6b00064Test.; Iyer R, Wehrmann L, Golden RL, Naraparaju K, Croucher JL, MacFarland SP et al. Entrectinib is a potent inhibitor of Trk-driven neuroblastomas in a xenograft mouse model. Cancer Lett. 2016;372(2):179–186. https://doi.org/10.1016/j.canlet.2016.01.018Test.; Rolfo C, Ruiz R, Giovannetti E, Gil-Bazo I, Russo A, Passiglia F et al. Entrectinib: a potent new TRK, ROS1, and ALK inhibitor. Expert Opin Investig Drugs. 2015;24(11):1493–1500. https://doi.org/10.1517/13543784.2015.1096344Test.; Harada G, Santini FC, Wilhelm C, Drilon A. NTRK fusions in lung cancer: From biology to therapy. Lung Cancer. 2021;161:108–113. https://doi.org/10.1016/j.lungcan.2021.09.005Test.; Drilon A, Siena S, Dziadziuszko R, Barlesi F, Krebs MG, Shaw AT et al. Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1-2 trials. Lancet Oncol. 2020;21(2):261–270. https://doi.org/10.1016/S1470-2045Test(19)30690-4.; Dziadziuszko R, Krebs MG, De Braud F, Siena S, Drilon A, Doebele RC et al. Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer. J Clin Oncol. 2021;39(11):1253–1263. https://doi.org/10.1200/JCO.20.03025Test.; Drilon A, Chiu C-H, Fan Y, Cho BC, Lu S, Ahn M-J et al. Long-Term Efficacy and Safety of Entrectinib in ROS1 Fusion–Positive NSCLC. JTO Clin Res Rep. 2022;3(6):100332. https://doi.org/10.1016/j.jtocrr.2022.100332Test.; Lim SM, Kim HR, Lee JS, Lee KH, Lee YG, Min YJ et al. Open-Label, Multicenter, Phase II Study of Ceritinib in Patients With Non-Small-Cell Lung Cancer Harboring ROS1 Rearrangement. J Clin Oncol. 2017;35(23):2613–2618. https://doi.org/10.1200/JCO.2016.71.3701Test.; Shaw AT, Solomon BJ, Chiari R, Riely GJ, Besse B, Soo RA et al. Lorlatinib in advanced ROS1-positive non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 1-2 trial. Lancet Oncol. 2019;20(12):1691–1701. https://doi.org/10.1016/S1470-2045Test(19)30655-2.; Doebele RC, Lin J, Nagasaka M, Baik C, Van Der Wekken A et al. MA11.07 Phase 1/2 TRIDENT-1 Study of Repotrectinib in Patients with ROS1+ or NTRK+ Advanced Solid Tumors. J Thor Oncol. 2021;16(3):S174–175. https://doi.org/10.1016/j.jtho.2021.01.251Test.; Ou SI, Fujiwara Y, Shaw AT, Yamamoto N, Nakagawa K, Fan F et al. Efficacy of Taletrectinib (AB-106/DS-6051b) in ROS1+ NSCLC: An Updated Pooled Analysis of U.S. and Japan Phase 1 Studies. JTO Clin Res Rep. 2020;2(1):100108. https://doi.org/10.1016/j.jtocrr.2020.100108Test.; Rodrigus P, de Brouwer P, Raaymakers E. Brain metastases and non-small cell lung cancer. Prognostic factors and correlation with survival after irradiation. Lung Cancer. 2001;32(2):129–136. https://doi.org/10.1016/s0169-5002Test(00)00227-0.; Dziadziuszko R, Hung T, Wang K, Choeurng V, Drilon A, Doebele RC et al. Pre- and post-treatment blood-based genomic landscape of patients with ROS1 or NTRK fusion-positive solid tumours treated with entrectinib. Mol Oncol. 2022;16(10):2000–2014. https://doi.org/10.1002/1878-0261.13214Test.; Liu D, Flory J, Lin A, Offin M, Falcon CJ, Murciano-Goroff YR et al. Characterization of on-target adverse events caused by TRK inhibitor therapy. Ann Oncol. 2020;31(9):1207–1215. https://doi.org/10.1016/j.annonc.2020.05.006Test.; Drilon A. TRK inhibitors in TRK fusion-positive cancers. Ann Oncol. 2019;30(Suppl. 8):viii23–viii30. https://doi.org/10.1093/annonc/mdz282Test.; Sartore-Bianchi A, Pizzutilo EG, Marrapese G, Tosi F, Cerea G, Siena S. Entrectinib for the treatment of metastatic NSCLC: safety and efficacy. 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الإتاحة: https://doi.org/10.21518/ms2023-421Test
https://doi.org/10.1158/1078-0432.CCR-18-1052Test
https://doi.org/10.1073/pnas.1311707110Test
https://doi.org/10.1158/0008-5472.CAN-18-1492Test
https://doi.org/10.1158/1078-0432.CCR-12-0550Test
https://doi.org/10.1158/1078-0432.CCR-12-2851Test
https://doi.org/10.1200/JCO.2011.35.6345Test
https://doi.org/10.18632/oncotarget.18408Test
https://doi.org/10.1200/PO.17.00063Test
https://doi.org/10.1200/JCO.2014.58.3302Test -
9دورية أكاديمية
المؤلفون: MAMATHA, PALANATI, D. V. R. N., BHIKSHAPATHI
المصدر: International Journal of Pharmacy and Pharmaceutical Sciences; Vol 16, Issue 2, 2024; 12-16 ; 0975-1491 ; 2656-0097
مصطلحات موضوعية: Pemigatinib, Entrectinib, Biliary tract cancer, Nanosponges, Cytotoxicity, Cell lines
وصف الملف: application/pdf; text/html
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10
المؤلفون: Patrício, João Pedro Vilar Miguel
المساهمون: Costa, Luís António Marques da, Mansinho, André Miguel Branco, Repositório da Universidade de Lisboa
مصطلحات موضوعية: Fusões de gene NTRK, Entrectinib, Larotrectinib, Prognóstico, Eficácia, Oncobiologia, Domínio/Área Científica::Ciências Médicas
وصف الملف: application/pdf