دورية أكاديمية
Outcomes in patients undergoing multivessel percutaneous coronary intervention using sirolimus-eluting stents: a report from the e-SELECT registry.
| العنوان: | Outcomes in patients undergoing multivessel percutaneous coronary intervention using sirolimus-eluting stents: a report from the e-SELECT registry. |
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| المؤلفون: | Cuculi, Florim, Banning, Adrian P., Abizaid, Alexander, Bartorelli, Antonio L., Baux, Ana C., Dzavik, Vladimir, Ellis, Stepehen, Gao, Runlin, Holmes, David, Jeong, Myung H., Legrand, Victor, Neumann, Franz-Josef, Nyakern, Maria, Spaulding, Christian, Stoll, Hans-Peter, Worthley, Stephen, Urban, Philip |
| المصدر: | EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 7 (8), 962-8 (2011) |
| بيانات النشر: | Société Europa Edition |
| سنة النشر: | 2011 |
| المجموعة: | University of Liège: ORBi (Open Repository and Bibliography) |
| مصطلحات موضوعية: | Aged, Angioplasty, Balloon, Coronary, Antibiotics, Antineoplastic/administration & dosage, Coronary Disease/pathology/therapy, Coronary Vessels/pathology, Drug-Eluting Stents, Female, Humans, Male, Middle Aged, Registries, Sirolimus/administration & dosage, Treatment Outcome, Human health sciences, Cardiovascular & respiratory systems, Sciences de la santé humaine, Systèmes cardiovasculaire & respiratoire |
| الوصف: | peer reviewed ; AIMS: Performing percutaneous coronary intervention (PCI) to multiple coronary lesions during the same procedure has potential economic and social advantages. However comprehensive outcome data of real world practice in a large population is limited. We aimed to compare short- and long-term outcomes between patients with multivessel coronary artery disease who either underwent single- or multivessel PCI within the e-SELECT registry. METHODS AND RESULTS: The e-SELECT registry combines data collected at 320 medical centres in 56 countries where patients received CYPHER Select(R) or CYPHER Select(R) Plus sirolimus-eluting stent (SES). Rates of myocardial infarction and major adverse cardiac event (MACE) (defined as any death, myocardial infarction or target lesion revascularisation) were compared between patients undergoing single-vessel versus multivessel PCI. A total of 15,147 patients who satisfied the inclusion criteria were included in the e-SELECT registry. Two thousand two hundred and seventy-eight (2,278) subjects (15%) underwent multivessel PCI and 12,869 (85%) had single-vessel PCI. The mean age was higher in the multivessel PCI group (63 vs. 62 years, p<0.001) and there was a higher prevalence of diabetes mellitus (32.4 vs. 30.0%, p=0.02). Lesions were more complex in the single-PCI group while pre- and post-dilatation were less common in the multivessel PCI group. Myocardial infarction within the first 30 days post PCI was more common in the multivessel PCI group (1.9 vs. 0.8%, p<0.001) and most of the infarctions were periprocedural (1.3 vs. 0.6%, p=0.001). Mortality and myocardial infarction at one-year were higher in the multivessel PCI group resulting in a significantly higher MACE (6.1 vs. 4.6%, p=0.005). CONCLUSIONS: Overall procedural and one year outcomes were excellent for both single- and multivessel procedures. However despite lower lesion complexity, performing multivessel PCI was associated with higher rates of periprocedural myocardial infarction and MACE when ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1774-024X 1969-6213 |
| العلاقة: | urn:issn:1774-024X; urn:issn:1969-6213; https://orbi.uliege.be/handle/2268/169679Test; info:hdl:2268/169679; https://orbi.uliege.be/bitstream/2268/169679/1/Cuculi%20et%20al%20EuroInterv.pdfTest; scopus-id:2-s2.0-84855364855; info:pmid:22157482 |
| DOI: | 10.4244/EIJV7I8A152 |
| الإتاحة: | https://doi.org/10.4244/EIJV7I8A152Test https://orbi.uliege.be/handle/2268/169679Test https://orbi.uliege.be/bitstream/2268/169679/1/Cuculi%20et%20al%20EuroInterv.pdfTest |
| حقوق: | open access ; http://purl.org/coar/access_right/c_abf2Test ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.AB89EDD9 |
| قاعدة البيانات: | BASE |
| تدمد: | 1774024X 19696213 |
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| DOI: | 10.4244/EIJV7I8A152 |