المؤلفون: Katherine A. Gentry, Elke Prade, Carlo Barnaba, Meng Zhang, Mukesh Mahajan, Sang-Choul Im, G. M. Anantharamaiah, Satoshi Nagao, Lucy Waskell, Ayyalusamy Ramamoorthy

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2045-2322Test

الوصول الحر: https://doaj.org/article/25723ddda3f34b8b832c8fae21511602Test

المؤلفون: Manuel Hora, Riddhiman Sarkar, Vanessa Morris, Kai Xue, Elke Prade, Emma Harding, Johannes Buchner, Bernd Reif

المصدر: PLoS ONE, Vol 12, Iss 7, p e0181799 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC5528828?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/8385323faf984c73a88bfdb03891255dTest

المؤلفون: Andreas Unsoeld, David Mentrup, Elke Prade, Anne Zeck, Ingo Gorr, Fabian Stiefel, Erik Arango Gutierrez

المصدر: Biotechnology and Bioengineering

مصطلحات موضوعية: Reducing agent, medicine.drug_class, Cell Culture Techniques, Bioengineering, CHO Cells, Monoclonal antibody, Applied Microbiology and Biotechnology, Redox, Article, ARTICLES, Cricetulus, redox‐sensitive modifications, medicine, bioprocess optimization, Animals, Cysteine, Disulfides, Bioprocess, biology, Bioprocess Engineering and Supporting Technologies, Chemistry, acidic charge variants, Antibodies, Monoclonal, product quality, Immunoglobulin G, Biophysics, biology.protein, Degradation (geology), Fermentation, Antibody, Biotechnology, Chromatography, Liquid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb67875f8f3481f1c6d754bbb0344c2Test
http://europepmc.org/articles/PMC7986432Test

المؤلفون: Aphrodite Kapurniotu, Ana C. Messias, Matthias J. Feige, Zheng Niu, Bernd Reif, Yonatan G. Mideksa, Chen Qian, Li-Mei Yan, Carlo Camilloni, Markus Fleisch, Don C. Lamb, Alexander Jussupow, Elke Prade, Michael Sattler, Kathleen Hille, Eleni Malideli, Riddhiman Sarkar

المصدر: Angewandte Chemie (International Ed. in English)
Adv. Mater. 59, 5820-5830 (2020)
Angew. Chem.-Int. Edit. 59, 2-13 (2020)

مصطلحات موضوعية: Amyloid, Peptide, amyloid formation, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Catalysis, Fluorescence spectroscopy, Substrate Specificity, medicine, Molecule, ddc:630, Amino Acid Sequence, Nuclear Magnetic Resonance, Biomolecular, solid-state NMR spectroscopy, Research Articles, Aβ, chemistry.chemical_classification, Amyloid-bildung, Amyloid-inhibitoren, Festkörper-nmr-spektroskopie, Amyloid beta-Peptides, 010405 organic chemistry, Chemistry, Amyloid Formation, Amyloid Inhibitors, A Beta, Solid-state Nmr Spectroscopy, Peptides, General Medicine, General Chemistry, Nuclear magnetic resonance spectroscopy, Peptide Fragments, 0104 chemical sciences, ddc, Islet Amyloid Polypeptide, Mechanism of action, Microscopy, Fluorescence, Biophysics, peptides, Aβ amyloid, medicine.symptom, Function (biology), Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5bac7e5a286d7746d16df0f3a9ae13Test
https://pubmed.ncbi.nlm.nih.gov/31863711Test

المؤلفون: Mukesh Mahajan, Katherine A. Gentry, Sang Choul Im, Ayyalusamy Ramamoorthy, Gattadahalli M. Anantharamaiah, Lucy Waskell, Meng Zhang, Elke Prade

المصدر: Angewandte Chemie. 130:8594-8598

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Flavin Mononucleotide, 010402 general chemistry, Redox, 01 natural sciences, Article, Catalysis, Electron transfer, 03 medical and health sciences, Cytochrome P-450 Enzyme System, Lipid bilayer, biology, Mechanism (biology), Chemistry, Cytochrome P450 reductase, Cytochrome P450, General Chemistry, Nuclear magnetic resonance spectroscopy, General Medicine, Nanostructures, 0104 chemical sciences, 030104 developmental biology, Membrane protein, biology.protein, Biophysics, Peptides, Oxidation-Reduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8a6cab13b7eabb0a62ebf6ba9dcd8eTest
https://doi.org/10.1002/ange.201802210Test

المؤلفون: Gattadahalli M. Anantharamaiah, Elke Prade, Mukesh Mahajan, Thirupathi Ravula, Ayyalusamy Ramamoorthy

المصدر: Chem Commun (Camb)

مصطلحات موضوعية: Models, Molecular, Reductase, 010402 general chemistry, 01 natural sciences, Redox, Catalysis, Article, Protein–protein interaction, Cytochrome P-450 Enzyme System, Protein Interaction Mapping, Materials Chemistry, Animals, Humans, Protein Interaction Maps, Nuclear Magnetic Resonance, Biomolecular, NADPH-Ferrihemoprotein Reductase, chemistry.chemical_classification, Redox complex, Obligate, biology, 010405 organic chemistry, Chemistry, Metals and Alloys, Cytochrome P450, General Chemistry, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Membrane, Enzyme, Ceramics and Composites, Biophysics, biology.protein, Rabbits, Oxidation-Reduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d6bec17beb040f836564a73d4f55f5Test
https://pubmed.ncbi.nlm.nih.gov/31041432Test

المؤلفون: Andrea Caporale, Gerhard Rammes, Li-Mei Yan, Michael Kracklauer, Tatjana Neumüller, Bernd Reif, Karine Farbiarz, Maria Bakou, Anna Spanopoulou, Erika Andreetto, Eleni Malideli, Aphrodite Kapurniotu, Marianna Tatarek-Nossol, Elke Prade

المصدر: Angewandte Chemie. 127:13287-13292

مصطلحات موضوعية: General Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a7c317b10b2333b861be9acb9e15b6c2Test
https://doi.org/10.1002/ange.201504973Test

المؤلفون: Eleni Malideli, Andrea Caporale, Michael Kracklauer, Karine Farbiarz, Erika Andreetto, Anna Spanopoulou, Tatjana Neumüller, Aphrodite Kapurniotu, Li-Mei Yan, Bernd Reif, Maria Bakou, Gerhard Rammes, Marianna Tatarek-Nossol, Elke Prade

المصدر: Angewandte Chemie (Int. ed., Print) 54 (2015): 13095–13100. doi:10.1002/anie.201504973
info:cnr-pdr/source/autori:Andreetto, Erika; Malideli, Eleni; Yan, Li-Mei; Kracklauer, Michael; Farbiarz, Karine; Tatarek-Nossol, Marianna; Rammes, Gerhard; Prade, Elke; Neumueller, Tatjana; Caporale, Andrea; Spanopoulou, Anna; Bakou, Maria; Reif, Bernd; Kapurniotu, Aphrodite/titolo:A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly/doi:10.1002%2Fanie.201504973/rivista:Angewandte Chemie (Int. ed., Print)/anno:2015/pagina_da:13095/pagina_a:13100/intervallo_pagine:13095–13100/volume:54

مصطلحات موضوعية: Amyloid, Surface Properties, protein-protein interactions, Peptide, Protein aggregation, Catalysis, Protein–protein interaction, Protein Aggregates, Alzheimer Disease, Amyloid precursor protein, medicine, Humans, islet amyloid polypeptide, chemistry.chemical_classification, Amyloid beta-Peptides, biology, amyloid inhibitors, P3 peptide, General Chemistry, Alzheimer's disease, medicine.disease, Biochemistry of Alzheimer's disease, Diabetes Mellitus, Type 2, chemistry, Biochemistry, Drug Design, biology.protein, Biophysics, beta-amyloid peptide

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101355da42e807627e1fd77e2a12e3a1Test
https://doi.org/10.1002/anie.201504973Test

المؤلفون: Maria Stavropoulou, Carsten Peters, Andi Mainz, Jirka Peschek, Johannes Buchner, Katrin C. Back, Bernd Reif, Sevil Weinkauf, Elke Prade, Benjamin Bardiaux, Sam Asami

المساهمون: Department of Chemistry [Munich], Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Leibniz Forschungsinstitut für Molekulare Pharmakolgie = Leibniz Institute for Molecular Pharmacology [Berlin, Allemagne] (FMP), Leibniz Association, Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Helmholtz-Zentrum München (HZM), This work was performed in the framework of the SFB-1035 (project B07 to B.R. and project A06 to J.B. and S.W., German Research Foundation (DFG)). We acknowledge support from the Helmholtz-Gemeinschaft and the DFG (grant Re1435 to B.R.). We are grateful to the Center for Integrated Protein Science Munich for financial support. J.P. acknowledges support from the Studienstiftung des deutschen Volkes., We are grateful to H. Oschkinat, S. Markovic and J. Muenckemer for stimulating discussions on the project. We also thank M. Ringling, H. Stephanowitz and A. Nieuwkoop for technical support with the EM, MS and fast MAS NMR experiments, respectively., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Helmholtz Zentrum München = German Research Center for Environmental Health

المصدر: Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2015, pp.898-905. ⟨10.1038/nsmb.3108⟩
Nature Structural and Molecular Biology, 2015, pp.898-905. ⟨10.1038/nsmb.3108⟩

مصطلحات موضوعية: Models, Molecular, Amyloid, Magnetic Resonance Spectroscopy, Protein Conformation, MESH: alpha-Crystallin B Chain, Peptide, Plasma protein binding, Protein aggregation, Models, Biological, 03 medical and health sciences, Protein structure, MESH: Protein Conformation, Structural Biology, Humans, MESH: Protein Binding, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, MESH: Amyloid, MESH: Humans, biology, MESH: Magnetic Resonance Spectroscopy, αb crystallin, 030302 biochemistry & molecular biology, An amyloid, MESH: Models, Biological, alpha-Crystallin B Chain, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Interaction studies, chemistry, Biochemistry, Chaperone (protein), Chaperone αB-crystallin, Structural plasticity, Amorphous, biology.protein, Biophysics, MESH: Models, Molecular, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378e5d41025faab2460349f7e2e1bb5cTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-01400959Test

المؤلفون: Gerd Multhaup, Elke Prade, Riddhiman Sarkar, Heiko J. Bittner, Juan Miguel López del Amo, Peter W. Hildebrand, Bernd Reif, Gerhard Althoff-Ospelt

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Amyloid, Plasma protein binding, macromolecular substances, Fibril, Biochemistry, Protein Structure, Secondary, Protein structure, Sulindac, Alzheimer Disease, mental disorders, medicine, Humans, Molecular Biology, Amyloid beta-Peptides, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Cell Biology, medicine.disease, Small molecule, Protein Structure and Folding, Biophysics, Salt bridge, Alzheimer's disease, Hydrophobic and Hydrophilic Interactions, medicine.drug, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f147c1d01b26fae101e527677407dc0Test
https://europepmc.org/articles/PMC4661391Test/