التفاصيل البيبلوغرافية
| العنوان: |
Medical and Neuro-Oncology |
| المؤلفون: |
Barker, Christopher A., Chang, Maria, Lassman, Andrew B., Beal, Kathryn, Chan, Timothy A., Hunter, Kathy, Grisdale, Kathleen, Ritterhouse, Melesa, Moustakas, Argirios, Iwamoto, Fabio M., Kreisl, Teri N., Sul, Joohee, Kim, Lyndon, Butman, John, Albert, Paul, Fine, Howard A., Chamberlain, Marc C., Alexandru, Daniela, Glantz, Michael J., Bota, Daniela A., Takahashi, Kenkichi, Ikeda, Naokado, Kajimoto, Yoshinaga, Miyatake, Shinichi, Kuroiwa, Toshihiko, Iwamoto, Fabio, Lamborn, Kathleen, Kuhn, John, Wen, Patrick, Yung, W.K.A., Gilbert, Mark, Chang, Susan, Lieberman, Frank, Prados, Michael, Fine, Howard, Lu-Emerson, Christine, Norden, Andrew D., Drappatz, Jan, Quant, Eudocia C., Ciampa, Abigail S., Doherty, Lisa M., LaFrankie, Debra C., Wen, Patrick Y., Sherman, Jonathan H., Moldovan, Krisztina, Yeoh, Hian K., Starke, Bobby M., Pouratian, Nader, Shaffrey, Mark E., Schiff, David, O'Connor, Patrick C., Kroon, Henk-Andre, Recht, Lawrence, Montano, Nicola, Cenci, Tonia, Martini, Maurizio, D'Alessandris, Quintino G., Banna, Giuseppe L., Maira, Giulio, De Maria, Ruggero, Larocca, Luigi M., Pallini, Roberto, Kim, Choong Hyun, Yang, Mun Sul, Cheong, Jin Hwan, Kim, Jae Min, Shonka, Nicole, Alfred Yung, W. K., Piao, Yuji, Liu, Jun, Bekele, Nebiyou, Chen, Alice, Heymach, John, de Groot, John, Gilbert, Mark R., Wang, Meihua, Aldape, Ken, Sorensen, A. Gregory, Mikkelsen, Tom, Bokstein, Felix, Woo, Shaio Y., Chmura, Steven J., Choucair, Ali K., Mehta, Minesh, Perez Segura, Pedro, Gil, M, Balañá, C, Chacon, I, Muñoz, J, Martin, M, Flowers, Alexandra, Salner, Andrew, Gaziel, Tine B., Soerensen, Morten, Hasselbalch, Benedikte, Poulsen, Hans Skovgaard, Lassen, Ulrik, Peyre, Matthieu, Cartalat-Carel, Stéphanie, Meyronet, David, Sunyach, Marie-Pierre, Jouanneau, Emmanuel, Guyotat, Jacques, Jouvet, Anne, Frappaz, Didier, Honnorat, Jerôme, Ducray, François, Wagle, Naveed, Nghiemphu, Phioanh L., Lai, Albert, Cloughesy, Timothy F., Kairouz, Victor F., Elias, Elias F., Chahine, Georges Y., Comair, Youssef G., Dimassi, H., Kamar, Francois G., Parchman, Andrew J., Nock, Charles J., Bartolomeo, Julie, Ruland, Sandra, Beroukhim, Rameen, Graber, Jerome J., Kaley, Thomas, Johnson, Derek R., Kimmel, David W., Burch, Patrick A., Cascino, Terrence L., Giannini, Caterina, Wu, Wenting, Buckner, Jan C., Dirier, Ahmet, Abacioglu, Ufuk, Okkan, Sait, Pak, Yucel, Guney, Yildiz Yukselen, Aksu, Gorkem, Soyuer, Serdar, Oksuzoglu, Berna, Meydan, Deniz, Zincircioglu, Burhanedtin, Yumuk, Perran Fulden, Alco, Gul, Keven, Emine, Ucer, Ali Riza, Tsung, Andrew J., Prabhu, Sujit S., Shonka, Nicole A., Alistar, Angela T., van den Bent, Martin, Taal, Walter, Sleijfer, Stefan, van Heuvel, Irene, Smitt, Peter A. Sillevis, Bromberg, Jacoline E., Vernhout, Irene, Porter, Alyx B., Dueck, Amylou C., Karlin, Nina J., Hiramatsu, Ryo, Kawabata, Shinji, Miyatake, Shin-Ichi, Easson, Michael W., Vicente, M. Graça H., Sahebjam, Solmaz, Garoufalis, Evgenia, Guiot, Marie Christine, Muanza, Thierry, Del Maestro, Ronaldo, Kavan, Petr, Smolin, Alexey V., Konev, Andrey, Nikolaeva, Svetlana, Shamanskaya, Yulia, Malysheva, Alexandra, Strelnikov, Vladimir, Vranic, Andrej, Prestor, Borut, Pizem, Joze, Popovic, Mara, Khatua, Soumen, Finlay, Jonathan, Nelson, Marvin, Gonzalez, Ignacio, Bruggers, Carol, Dhall, Girish, Fu, Beverly Dan, Linskey, Mark, Bota, Daniela, Walbert, Tobias, Puduvalli, Vinay, Ozawa, Tatsuya, Brennan, Cameron W., Wang, Lu, Squatrito, Massimo, Sasayama, Takashi, Nakada, Mitsutoshi, Huse, Jason T., Pedraza, Alicia, Utsuki, Satoru, Tandon, Adesh, Fomchenko, Elena I., Oka, Hidehiro, Levine, Ross L., Fujii, Kiyotaka, Ladanyi, Marc, Holland, Eric C., Raizer, Jeffrey, Avram, Michael J., Kaklamani, Virginia, Cianfrocca, Mary, Gradishar, William, Helenowski, Irene, McCarthy, Katie, Mulcahy, Mary, Rademaker, Alfred, Grimm, Sean, Landolfi, Joseph C., Chen, Shan, Peeraully, Tasneem, Anthony, Patty, Linendoll, Nadine M., Zhu, Jay-Jiguang, Yao, Kevin, Mignano, John, Pfannl, Rolf, Pan, Edward, Vera-Bolanos, Elizabeth, Armstrong, Terri S., Bekele, B. N., Albrecht, Valerie, Juerchott, Kathrin, Selbig, Joachim, Tonn, Jörg-Christian, Schichor, Christian, Sawale, Kunal B., Wolff, Johannes, Vats, Tribhawan, Ketonen, Leena, Khasraw, Mustafa, Panageas, Katherine, Reiner, Anne, Goldlust, Samuel, Tabar, Vivian, Green, Richard M., Woyshner, Emily A., Abe, Tatsuya, Morishige, Masaki, Shiqi, Kong, Momii, Yasutomo, Sugita, Kenji, Fukuyoshi, Yuki, Kamida, Tohru, Fujiki, Minoru, Kobayashi, Hidenori, Lavon, Iris, Refael, Miri, Zrihan, Daniel, Siegal, Tali, Tham, Chee Kian, See, Siew Ju, Toh, Chee Keong, Kang, Shin-Hyuk, Park, Kyung-Jae, Kim, Chae-Yong, Yu, Mi Ok, Park, Chul-Kee, Park, Sung-Hye, Chung, Yong-Gu, Cho, Tai-Hyoung, Sasaki, Hikaru, Sano, Keisyo, Nariai, Tadashi, Uchino, Yoshio, Kitamura, Yohei, Ohira, Takayuki, Yoshida, Kazunari, Kirson, Eilon D., Wasserman, Yoram, Izhaki, Aviran, Mordechovich, Daniel, Gurvich, Zoya, Dbaly, Vladimir, Vymazal, Joseph, Tovarys, Frantisek, Salzberg, Marc, Rochlitz, Cristoph, Goldsher, Dorit, Palti, Yoram, Ram, Zvi, Gutin, Philip H., Roger Stupp on behalf of the EF-11 study investigators, Furuse, Motomasa, Torcuator, Roy G., Ibaoc, Khalil, Rafael, Antonio, Mariano, Manuel, Reardon, David A., Peters, Katherine, Desjardins, Annick, Sampson, John, Vredenburgh, James J., Gururangan, Sri, Friedman, Henry S., Le Rhun, Emilie, Kotecki, Nuria, Zairi, Fahed, Baranzelli, Marie Christine, Faivre-Pierret, Matthieu, Dubois, Francois, Bonneterre, Jacques, Arenson, Edward B., Arenson, Julianne D., Arenson, Patricia K., Pierick, Mary, Jensen, Wade, Smith, Don B., Wong, Eric T., Gautam, Shiva, Malchow, Christopher, Lun, Melody, Brem, Steven, Chandler, James, Muro, Kenji, Rice, Laurie, Mrugala, Maciej, Johnston, Sandra K., Chamberlain, Marc, Marosi, Christine, Handisurya, Ammon, Kautzky-Willer, Alexandra, Preusser, Matthias, Elandt, Katarzyna, Widhalm, Georg, Dieckmann, Karin, Opinaldo, Paul, Chua, Evelyn, Barredo, Carlo, Cuanang, Joven, Phuphanich, Surasak, Recht, Lawrence D., Rosenfeld, Steven S., Fadul, Camilo E., Swabb, Edward A., Pope, Cathy, Beelen, Andrew P., Raizer, Jeffrey J., Kim, Il Han, Han, Jung Ho, Lee, Se-Hoon, Kim, Tae Min, Kim, Dong-Wan, Kim, Jeong Eun, Paek, Sun Ha, Kim, In Ah, Kim, Yu Jung, Kim, Jee Hyun, Nam, Do-Hyun, Rhee, Chang Hun, Lee, Seung Hoon, Park, Byung-Joo, Kim, Dong Gyu, Heo, Dae Seog, Jung, Hee-Won, Peters, Katherine B., Becker, Kevin, Baehring, Joachim, Hammond, Samantha N., Fisher, David C., Cote, Gregory M., Ruland, Sandra F., Brandes, Alba A., Franceschi, Enrico, Tosoni, Alicia, Poggi, Rosalba, Agati, Raffaele, Bartolini, Stefania, Spagnolli, Federica, Pozzati, Eugenio, Marucci, Gianluca, Ermani, Mario, Taillibert, Sophie, Guillevin, Rémy, Dehais, Caroline, Bellanger, Agnès, Delattre, Jean-Yves, Omuro, Antonio, Hoang-Xuan, Khê, Barrie, Maryline, Guiu, Séverine, Chauffert, Bruno, Taillandier, Luc, Fabbro, Michel, Laigre, Maryline, Guillamo, Jean-Sébastien, Geffrelot, Julien, Rouge, Thibault de la Motte, Bonnetain, Franck, Chinot, Olivier, on behalf of the ANOCEF Group, Gil, Miguel J., de las Peñas, Ramón, Reynes, Gaspar, Balaña, Carmen, Perez-Segura, Pedro, Garcia-Velasco, Adelaida, Gallego, Oscar, Herrero, Ana, de Lucas, Concepción Fernández-Chacón, Benavides, Manual, Perez-Martin, Xavier, Mesia, Carlos, Martínez-Garcia, María, Muggeri, Alejandro D., Cervio, Andres, Rojas, Matias, Arakaki, Naomi, Sevlever, Gustavo E., Diez, Blanca D., Cerrato, Sebastian, Martinetto, Horacio, Peereboom, David M., Brewer, Cathy J., Suh, John H., Chao, Sam T., Parsons, Michael W., Elson, Paul J., Vogelbaum, Michael A., Sade, Burak, Barnett, Gene H., Yung, W. K. A., Kobyakov, Grigory, Absalyamova, O., Amanov, R., Rauschkolb, Paula K., Batchelor, Tracy T., Meyer, Louise P., Lallana, Enrico C., Kohanteb, Pedram, Mrugala, Maciej M., Lee, Laurie K., Graham, Carrie A., Fink, James R., Spence, Alexander M., Portnow, Jana, Badie, Behnam, Liu, Xueli, Frankel, Paul, Chen, Mike, Synold, Timothy W., Al Jishi, Ahmed A., Golan, Jeff, Polley, Mei-Yin C., Lamborn, Kathleen R., Chang, Susan M., Butowski, Nicholas, Clarke, Jennifer L., Grommes, Christian, Oxnard, Geoffrey R., Kris, Mark G., Miller, Vincent A., Pao, William, Renfrow, Jackie, DeTroye, Alisha, Chan, Michael, Tatter, Stephen, Ellis, Thomas, McMullen, Kevin, Johnson, Annette, Mott, Ryan, Lesser, Glenn J., Cavaliere, Robert, Abrey, Lauren E., Mason, Warren P., Perentesis, John, Ivy, Percy, Villalona, Miguel, Nayak, Lakshmi, Fleisher, Martin, Gonzalez-Espinoza, Rita, Lin, Oscar, Liu, Chhiu-Mei, Deangelis, Lisa M., Taylor, Lynne P., Ammirati, Mario, Lamki, Tarek, Zarzour, Hekmat, Grecula, John, Dudley, Roy W., Kavan, P., Garoufalis, E., Guiot, M.-C., Del Maestro, R. F., Maurice, Catherine, Belanger, K., Moumdjian, R., Dufresne, S., Fortin, C., Fortin, M. A., Berthelet, F., Renoult, E., Belair, M., Rouleau, D., Benavides, M., Segura, P. P., Balana, C., Gil, M. J. Gil, Berrocal, A., Reynes, G., Garcia, J. L., Mazarico, J., Bague, S. |
| بيانات النشر: |
Oxford University Press |
| سنة النشر: |
2010 |
| المجموعة: |
HighWire Press (Stanford University) |
| مصطلحات موضوعية: |
Abstracts |
| الوصف: |
INTRODUCTION: Patients with glioblastoma multiforme (GBM) are often prescribed antiepileptic drugs (AEDs) to treat or prevent seizures. Hepatic enzyme-inducing AEDs (EIAEDs) may enhance metabolism of antineoplastic chemotherapy, potentially abrogating therapeutic effects. However, a recent report paradoxically demonstrated improved survival of GBM patients treated with EIAEDs. We conducted this retrospective study to determine the effect of EIAEDs on survival of GBM patients. METHODS: Records of adults treated with radiation therapy (RT) for primary GBM were reviewed. Clinical data prognostic of survival in the RTOG recursive partitioning analysis, history of seizures prior to RT, and use of EIAEDs (such as phenytoin, fosphenytoin, phenobarbital, carbamazepine, or oxcarbazepine) and/or temozolomide (TMZ) during RT were recorded. Multivariable Cox regression models were created to determine the effects of RTOG RPA class, seizures, and EIAED or TMZ use on survival. A subgroup analysis of patients who received TMZ during RT was also undertaken. RESULTS: Among the 554 patients in the primary Cox regression model, 272 were taking an EIAED. RTOG RPA class and TMZ, but not EIAED use, were associated with longer survival (HRs [95% Cis] of 1.7 [1.6–1.8], 0.6 [0.4–0.9], 1.0 [0.8–1.2], respectively [p = 0.000001, 0.0003, and 0.8, respectively]). A marginally significant association of seizure history and survival was observed (HR 0.8, 95% CI: 0.6–1.0; p = 0.06). Restricting analysis to patients who received TMZ during RT (n = 181), we found that RTOG RPA class, but neither seizures nor EIAEDs, were associated with survival (HRs [95% Cis] of 1.7 [1.4–2.0], 1.3 [0.8–1.7], 1.3 [0.8–1.8]; p = 0.0001, 0.34, 0.28, respectively). CONCLUSION: Our findings did not reveal an association between EIAED use and survival in GBM patients. Consistent with prior studies, our data suggest that a history of seizures may portend better prognosis. The association of EIAEDs and improved survival in other studies may reflect this observation. ... |
| نوع الوثيقة: |
text |
| وصف الملف: |
text/html |
| اللغة: |
English |
| العلاقة: |
http://neuro-oncology.oxfordjournals.org/cgi/content/short/12/suppl_4/iv36Test; http://dx.doi.org/10.1093/neuonc/noq116.s6Test |
| DOI: |
10.1093/neuonc/noq116.s6 |
| الإتاحة: |
https://doi.org/10.1093/neuonc/noq116.s6Test
http://neuro-oncology.oxfordjournals.org/cgi/content/short/12/suppl_4/iv36Test |
| حقوق: |
Copyright (C) 2010, Society for Neuro-Oncology (SNO) |
| رقم الانضمام: |
edsbas.C3205CD8 |
| قاعدة البيانات: |
BASE |
