المؤلفون: Mody, Kabir, Jain, Prerna, El-Refai, Sherif M, Azad, Nilofer S, Zabransky, Daniel J, Baretti, Marina, Shroff, Rachna T, Kelley, R Katie, El-Khouiery, Anthony B, Hockenberry, Adam J, Lau, Denise, Lesinski, Gregory B, Yarchoan, Mark

المصدر: JCO Precision Oncology. 6(6)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Digestive Diseases, Cancer, Human Genome, Biotechnology, Genetics, Rare Diseases, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Bile Duct Neoplasms, Bile Ducts, Intrahepatic, Biliary Tract Neoplasms, Cholangiocarcinoma, Gallbladder Neoplasms, Genomics, Humans, Proto-Oncogene Proteins p21(ras), Transcriptome, Tumor Microenvironment, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3bv0431rTest

المؤلفون: Yap, TA, Krebs, MG, Postel-Vinay, S, El-Khouiery, A, Soria, J-C, Lopez, J, Berges, A, Cheung, SYA, Irurzun-Arana, I, Goldwin, A, Felicetti, B, Jones, GN, Lau, A, Frewer, P, Pierce, AJ, Clack, G, Stephens, C, Smith, SA, Dean, E, Hollingsworth, SJ

المساهمون: Lopez, Juanita

مصطلحات موضوعية: Antineoplastic Combined Chemotherapy Protocols, Ataxia Telangiectasia Mutated Proteins, Carboplatin, Humans, Indoles, Maximum Tolerated Dose, Morpholines, Neoplasms, Neutropenia, Nuclear Proteins, Protein Kinase Inhibitors, Pyrimidines, Sulfonamides, Sulfoxides, Thrombocytopenia

جغرافية الموضوع: United States

وصف الملف: Print; 5224; application/pdf

العلاقة: 1078-0432.CCR-21-1032; Clinical Cancer Research, 2021, 27 (19), pp. 5213 - 5224; https://repository.icr.ac.uk/handle/internal/5802Test

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-21-1032Test
https://repository.icr.ac.uk/handle/internal/5802Test

المؤلفون: Yap, Timothy, Krebs, Matthew, Postel-Vinay, Sophie, El-Khouiery, Anthony, Soria, Jean-Charles, Lopez, Juanita, Berges, Alienor, Cheung, S. Y. Amy, Irurzan-Arana, Itziar, Goldwin, Andrew, Felicetti, Brunella, Jones, Gemma, Lau, Alan, Frewer, Paul, Pierce, Andrew, Clack, Glen, Stephens, Christine, Smith, Simon, Dean, Emma Jane, Hollingsworth, Simon J.

المصدر: Yap , T , Krebs , M , Postel-Vinay , S , El-Khouiery , A , Soria , J-C , Lopez , J , Berges , A , Cheung , S Y A , Irurzan-Arana , I , Goldwin , A , Felicetti , B , Jones , G , Lau , A , Frewer , P , Pierce , A , Clack , G , Stephens , C , Smith , S , Dean , E J & Hollingsworth , S J 2021 , ' Ceralasertib (AZD6738), an oral ATR kinase inhibitor, in combination with carboplatin in patients ....

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-21-1032Test
https://research.manchester.ac.uk/en/publications/2530cfcc-aa53-4704-86c9-e45449c7d1d2Test
https://pure.manchester.ac.uk/ws/files/199596741/1078_0432.CCR_21_1032.full.pdfTest

المؤلفون: Kabir Mody, Prerna Jain, Sherif M. El-Refai, Nilofer S. Azad, Daniel J. Zabransky, Marina Baretti, Rachna T. Shroff, R. Katie Kelley, Anthony B. El-Khouiery, Adam J. Hockenberry, Denise Lau, Gregory B. Lesinski, Mark Yarchoan

المصدر: JCO precision oncology, vol 6, iss 6

مصطلحات موضوعية: Intrahepatic, Cancer Research, Human Genome, Genomics, Cholangiocarcinoma, Proto-Oncogene Proteins p21(ras), Bile Ducts, Intrahepatic, Biliary Tract Neoplasms, Rare Diseases, Bile Duct Neoplasms, Oncology, Tumor Microenvironment, Genetics, Humans, 2.1 Biological and endogenous factors, Gallbladder Neoplasms, Bile Ducts, Transcriptome, Digestive Diseases, Biotechnology, Cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cfc5e60be92e25ac22bfced4a74093Test
https://doi.org/10.1200/po.21.00510Test

المؤلفون: Brunella Felicetti, Paul Frewer, Juanita Lopez, Anthony El-Khouiery, Glen Clack, Christine Stephens, Simon J. Hollingsworth, Matthew G Krebs, Alan Lau, Andrew Goldwin, Alienor Berges, Jean-Charles Soria, Gemma N Jones, Sophie Postel-Vinay, Itziar Irurzun-Arana, Emma Dean, Sy Amy Cheung, Timothy A. Yap, Andrew J. Pierce, Simon Smith

المصدر: Yap, T, Krebs, M, Postel-Vinay, S, El-Khouiery, A, Soria, J-C, Lopez, J, Berges, A, Cheung, S Y A, Irurzan-Arana, I, Goldwin, A, Felicetti, B, Jones, G, Lau, A, Frewer, P, Pierce, A, Clack, G, Stephens, C, Smith, S, Dean, E J & Hollingsworth, S J 2021, ' Ceralasertib (AZD6738), an oral ATR kinase inhibitor, in combination with carboplatin in patients with advanced solid tumors: a Phase I study ', Clinical Cancer Research . https://doi.org/10.1158/1078-0432.CCR-21-1032Test

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Indoles, Neutropenia, Maximum Tolerated Dose, Anemia, Morpholines, Ataxia Telangiectasia Mutated Proteins, Gastroenterology, Carboplatin, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Adverse effect, Protein Kinase Inhibitors, Sulfonamides, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Nuclear Proteins, Common Terminology Criteria for Adverse Events, medicine.disease, Thrombocytopenia, Pyrimidines, Oncology, Tolerability, chemistry, Pharmacodynamics, Sulfoxides, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5158d7388a6bd09605d2ca9977160f12Test
https://pubmed.ncbi.nlm.nih.gov/34301752Test

المؤلفون: Gordon, Michael A, Zhang, Wu, Yang, Dongyun, Iqbal, Syma, El-Khouiery, Anthony, Nagashima, Fumio, Lurje, Georg, Labonte, Melissa, Wilson, Peter, Sherrod, Andy, Ladner, Robert D, Lenz, Heinz-Josef, LaBonte Wilson, Melissa

المصدر: Gordon , M A , Zhang , W , Yang , D , Iqbal , S , El-Khouiery , A , Nagashima , F , Lurje , G , Labonte , M , Wilson , P , Sherrod , A , Ladner , R D , Lenz , H-J & LaBonte Wilson , M 2011 , ' Gender-specific genomic profiling in metastatic colorectal cancer patients treated with 5-fluorouracil and oxaliplatin ' , Pharmacogenomics , vol. 12 , no. 1 , pp. 27-39 . https://doi.org/10.2217/pgs.10.163Test

مصطلحات موضوعية: Adult, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols, Colorectal Neoplasms, Disease-Free Survival, Female, Fluorouracil, Gene Expression Profiling, Genotype, Humans, Male, Middle Aged, Neoplasm Metastasis, Organoplatinum Compounds, Polymerase Chain Reaction, Polymorphism, Genetic, Sex Characteristics, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

الإتاحة: https://doi.org/10.2217/pgs.10.163Test
https://pure.qub.ac.uk/en/publications/40469289-fb89-487d-b4e8-6bf547cc50f5Test