المؤلفون: Brian C. Mackness, Julie A. Jaworski, Ekaterina Boudanova, Anna Park, Delphine Valente, Christine Mauriac, Olivier Pasquier, Thorsten Schmidt, Mostafa Kabiri, Abdullah Kandira, Katarina Radošević, Huawei Qiu

المصدر: mAbs, Vol 11, Iss 7, Pp 1276-1288 (2019)

مصطلحات موضوعية: IgG antibodies, neonatal Fc receptor, mutagenesis, serum half-life, pH dependence, FcRn, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1942-0862Test; https://doaj.org/toc/1942-0870Test

الوصول الحر: https://doaj.org/article/33ccb6b5fc1f42d784a69baa02b5d1f8Test

المؤلفون: Huawei Qiu, Ronnie Wei, Julie Jaworski, Ekaterina Boudanova, Heather Hughes, Scott VanPatten, Anders Lund, Jaime Day, Yanfeng Zhou, Tracey McSherry, Clark Q. Pan, Rebecca Sendak

المصدر: mAbs, Vol 11, Iss 7, Pp 1266-1275 (2019)

مصطلحات موضوعية: Antibody engineering, deamidation, mutagenesis, developability, structure-function, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1942-0862Test; https://doaj.org/toc/1942-0870Test

الوصول الحر: https://doaj.org/article/930e74582c1343a88440d28599c59bdcTest

المؤلفون: Ruijun Zhang, Ponraj Prabakaran, Xiaocong Yu, Brian C. Mackness, Ekaterina Boudanova, Joern Hopke, Jose Sancho, Jacqueline Saleh, HyunSuk Cho, Ningning Zhang, Helene Simonds-Mannes, Samuel D. Stimple, Dietmar Hoffmann, Anna Park, Partha S. Chowdhury, Sambasiva P. Rao

المصدر: mAbs, Vol 13, Iss 1 (2021)

مصطلحات موضوعية: Antibody discovery, transgenic mouse, single B-cell cloning (SBC), phage display, monoclonal antibody (mAb), overlapping PCR, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1942-0862Test; https://doaj.org/toc/1942-0870Test

الوصول الحر: https://doaj.org/article/a782d91bddb64de78fcdc7be4359ef09Test

المؤلفون: Qun Zhou, Julie Jaworski, Yanfeng Zhou, Delphine Valente, Joanne Cotton, Denise Honey, Ekaterina Boudanova, Jochen Beninga, Ercole Rao, Ronnie Wei, Christine Mauriac, Clark Pan, Anna Park, Huawei Qiu

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: Effector functions, silencing, antibody, glycosylation switch, Fc engineering, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1942-0862Test; https://doaj.org/toc/1942-0870Test

الوصول الحر: https://doaj.org/article/52f85e2c458f442a984fd835414cf406Test

المؤلفون: Qun Zhou, Josephine Kyazike, Ekaterina Boudanova, Michael Drzyzga, Denise Honey, Robert Cost, Lihui Hou, Francis Duffieux, Marie-Priscille Brun, Anna Park, Huawei Qiu

المصدر: Pharmaceuticals, Vol 14, Iss 7, p 672 (2021)

مصطلحات موضوعية: site-specific antibody-drug conjugation, THIOMABTM, engineered double cysteine, PEGylation, conjugation efficiency and selectivity, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1424-8247/14/7/672Test; https://doaj.org/toc/1424-8247Test

الوصول الحر: https://doaj.org/article/1d1d4e9bcd2c468c9df96f3a0a831d57Test

المؤلفون: Thorsten Schmidt, Abdullah Kandira, Olivier Pasquier, Julie A. Jaworski, Ekaterina Boudanova, Katarina Radošević, Delphine Valente, Huawei Qiu, Christine Mauriac, Brian C. Mackness, Anna Park, Mostafa Kabiri

المصدر: mAbs

مصطلحات موضوعية: Protein Conformation, Immunology, Mutant, Bioengineering, Mice, Transgenic, Receptors, Fc, serum half-life, Mice, 03 medical and health sciences, 0302 clinical medicine, Neonatal Fc receptor, Rheumatoid Factor, Report, FcγR, Animals, Humans, Immunology and Allergy, Rheumatoid factor, pH dependence, Saturated mutagenesis, 030304 developmental biology, 0303 health sciences, neonatal Fc receptor, biology, Protein Stability, Chemistry, Histocompatibility Antigens Class I, Receptors, IgG, Mutagenesis, Wild type, Hydrogen-Ion Concentration, Molecular biology, Fragment crystallizable region, FcRn, Macaca fascicularis, 030220 oncology & carcinogenesis, Blood Circulation, Proteolysis, Mutagenesis, Site-Directed, biology.protein, IgG antibodies, Antibody, mutagenesis, Half-Life, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4c3ff471d5fe15ca1c71582de9f34cTest
https://doi.org/10.1080/19420862.2019.1633883Test

المؤلفون: HyunSuk Cho, Jacqueline Saleh, Sambasiva P. Rao, Partha S. Chowdhury, Joern Hopke, Samuel D. Stimple, Helene Simonds-Mannes, Jose Sancho, Xiaocong Yu, Ekaterina Boudanova, Ningning Zhang, Ruijun Zhang, Dietmar Hoffmann, Anna Park, Ponraj Prabakaran, Brian C. Mackness

المصدر: mAbs
article-version (VoR) Version of Record

مصطلحات موضوعية: Genetically modified mouse, Phage display, Immunology, Mammalian expression, Mice, Transgenic, Cell Separation, Computational biology, Cell Line, Workflow, Immunoglobulin Fab Fragments, 03 medical and health sciences, overlapping PCR, 0302 clinical medicine, Plasmid, Antibody Specificity, Peptide Library, Report, Animals, Humans, Immunology and Allergy, Selection (genetic algorithm), single B-cell cloning (SBC), 030304 developmental biology, B-Lymphocytes, 0303 health sciences, biology, Antibodies, Monoclonal, Flow Cytometry, High-Throughput Screening Assays, transgenic mouse, functional screening, Immunoglobulin G, 030220 oncology & carcinogenesis, biology.protein, Hybridoma technology, monoclonal antibody (mAb), phage display, Antibody, Cell Surface Display Techniques, linear expression cassettes (LECs), Spleen, Function (biology), Antibody discovery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf16c05ecdd684234a871e8c0e99ddcdTest
https://doi.org/10.1080/19420862.2021.1904546Test

المؤلفون: Christine Mauriac, Joanne Cotton, Yanfeng Zhou, Denise M. Honey, Ekaterina Boudanova, Ronnie Wei, Huawei Qiu, Qun Zhou, Ercole Rao, Anna Park, Jochen Beninga, Julie A. Jaworski, Clark Pan, Delphine Valente

المصدر: mAbs
article-version (VoR) Version of Record

مصطلحات موضوعية: Cytotoxicity, Immunologic, Glycosylation, glycosylation switch, Immunology, Mutation, Missense, Mutagenesis (molecular biology technique), Fc engineering, CHO Cells, Receptors, Fc, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Neonatal Fc receptor, Cricetulus, Antigen, Report, antibody, Immunology and Allergy, Animals, Humans, Complement Activation, 030304 developmental biology, Antibody-dependent cell-mediated cytotoxicity, 0303 health sciences, Effector functions, biology, Effector, Immunogenicity, Histocompatibility Antigens Class I, Cell biology, Immunoglobulin Fc Fragments, HEK293 Cells, chemistry, Amino Acid Substitution, 030220 oncology & carcinogenesis, silencing, biology.protein, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1a7ef973cb1183a883f32893b0ed09Test
http://europepmc.org/articles/PMC7531572Test

المؤلفون: Ted M. Ross, Thorsten U. Vogel, Irina V. Ustyugova, Anna Park, Simon Delagrave, Svetlana Stegalkina, Svetlana Pougatcheva, Ekaterina Boudanova, Jianxin Zhang, Yanfeng Zhou, Huawei Qiu, Ray Oomen, Sophia Mundle, Yu Qiu, Ponraj Prabakaran, Harry Kleanthous

المصدر: J Virol

مصطلحات موضوعية: 0301 basic medicine, Male, Models, Molecular, Glycosylation, medicine.drug_class, Protein Conformation, Immunology, Hemagglutinin (influenza), Hemagglutinin Glycoproteins, Influenza Virus, Monoclonal antibody, Antibodies, Viral, Microbiology, Epitope, Antigenic drift, Virus, 03 medical and health sciences, Epitopes, 0302 clinical medicine, Influenza A Virus, H1N1 Subtype, Antigen, Orthomyxoviridae Infections, Virology, Influenza, Human, medicine, Humans, Hemagglutination assay, biology, Structure and Assembly, Influenza A Virus, H3N2 Subtype, Vaccination, Antibodies, Monoclonal, Hemagglutination Inhibition Tests, Middle Aged, Antibodies, Neutralizing, 030104 developmental biology, Hemagglutinins, Influenza Vaccines, Insect Science, Drug Design, biology.protein, Antibody, Sequence Alignment, Sequence Analysis, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d254fe6c26a5dce67865466863794f50Test
https://europepmc.org/articles/PMC7158729Test/

المؤلفون: Michael Drzyzga, Denise M. Honey, Anna Park, Lihui Hou, Marie-Priscille Brun, Huawei Qiu, Qun Zhou, Robert Cost, Francis Duffieux, Ekaterina Boudanova, Josephine Kyazike

المصدر: Pharmaceuticals
Volume 14
Issue 7
Pharmaceuticals, Vol 14, Iss 672, p 672 (2021)

مصطلحات موضوعية: THIOMABTM, conjugation efficiency and selectivity, Mutant, Pharmaceutical Science, Mutagenesis (molecular biology technique), 01 natural sciences, Article, 03 medical and health sciences, Pharmacy and materia medica, Therapeutic index, Drug Discovery, 030304 developmental biology, 0303 health sciences, biology, 010405 organic chemistry, Chemistry, PEGylation, 0104 chemical sciences, RS1-441, Biochemistry, biology.protein, Medicine, Molecular Medicine, engineered double cysteine, Antibody, Selectivity, site-specific antibody-drug conjugation, Cysteine, Conjugate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedbaf9b98a3a3b8045f6f05f30c9115Test
https://doi.org/10.3390/ph14070672Test