المؤلفون: Katarzyna Mikula, Katarzyna Chojnacka, Dawid Skrzypczak, Piotr Młynarz, Anna Witek-Krowiak

المصدر: Journal of Functional Foods
Journal of Functional Foods, Vol 73, Iss, Pp 104146-(2020)

مصطلحات موضوعية: 0301 basic medicine, GSH, Herbal extract from Gentianae Radix, 3CLpro, 3C-like protease, TCH, Herbal extract from Loranthi Ramus, FFA, Free fatty acid, IC50, 50% inhibitory concentrations, Covid-19, Coronavirus Disease 2019, Phytochemicals, CDC, Cholesterol-dependent cytolysin, Medicine (miscellaneous), Pharmacology, medicine.disease_cause, GCG, Gallocatechin gallate, Bioactivity, CTH, Herbal extract from Cassiae Semen, MNP, Marine Natural Product, chemistry.chemical_compound, DNA, Deoxyribonucleic acid, MERS-CoV, Middle East Respiratory Syndrome Coronavirus, Mpro, The major protease, Betulinic acid, TX341-641, DBM, Herbal extract from Dioscoreae Rhizoma, PLpro, The papain-like protease, Coronavirus, chemistry.chemical_classification, Nutrition and Dietetics, Chemistry, food and beverages, Biological activity, 04 agricultural and veterinary sciences, 040401 food science, EC50, 50% effective concentration, Pharmacophore, PLY, Pneumolysin, Article, WHO, World Health Organization, 03 medical and health sciences, 0404 agricultural biotechnology, SARS-CoV, Severe Acute Respiratory Syndrome coronavirus, ACE2, Angiotensin-converting enzyme 2, medicine, RNA, Ribonucleic acid, Antiviral, ComputingMethodologies_COMPUTERGRAPHICS, 030109 nutrition & dietetics, Pandemic, Nutrition. Foods and food supply, CBE, CBM, Herbal extracts from Rhizoma Cibotii, Polyphenols, Plant extracts, MTT test, Cytotoxicity test using 3- (4,5-dimethylthiazol-2-yl) −2,5-diphenyltetrazolium bromide, Enzyme, CC50, 50% cytotoxicity concentration, Viral replication, Polyphenol, FA, Fatty acid, Luteolin, CPE, Cytopathogenic effect, Food Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14cee82201483e806e223697fbea2f9Test

المؤلفون: Shaoqi Shi, Xi Huang, Liang Xia, Qiulong Zhao

المصدر: Pharmacological Research

مصطلحات موضوعية: GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Anti-Inflammatory Agents, G-CSF, Granulocyte colony-stimulating factor, DMSO, dimethyl sulfoxide, RT-PCR, real-time polymerase chain reaction, TNF-α, tumor necrosis factor-α, Medicine, COVID-19, 2019 coronavirus disease, MOI, multiplicity of infection, anti-inflammatory, LS, Liu Shen capsule, CXCL-10/IP-10, interferon-inducible protein-10, TCID50, 100 × 50% tissue culture infective dose, NF-kappa B, MERS-CoV, Middle East respiratory syndrome coronavirus, antiviral, TC50, 50% toxicity concentration, CPE, cytopathic effect, FBS, foetal bovine serum, EC50, 50% effective concentration, Severe acute respiratory syndrome coronavirus, TCM, traditional Chinese medicine, MIP1a, Recombinant Macrophage Inflammatory Protein 1 Alpha, MTT, Methyl thiazolyl tetrazolium, Signal Transduction, IL-8, Interleukin-8, VERO, E6 cells Monkey kidney cell line, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Liu Shen capsule, medicine.drug_class, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV, severe acute respiratory syndrome coronavirus, PBS, phosphate-buffered saline, Antiviral Agents, Article, Anti-inflammatory, Humans, IL-1β, Interleukin-1beta, IL-6, Interleukin-6, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, SARS-CoV-2, business.industry, Lianhuaqingwen, COVID-19, Virology, Nf κb signaling, CCL-2/MCP-1, monocyte chemoattracctant protein-1, SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2, HPLC, high-performance liquid chromatography, business, Drugs, Chinese Herbal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa5470961f13b4dd1f69a55b86505b8Test
https://doi.org/10.1016/j.phrs.2020.105289Test

المؤلفون: Shaw, J, Fishwick, C, Harris, M

المصدر: Antiviral Research

مصطلحات موضوعية: NS2, Autoprotease, Inhibitor, viruses, Hepacivirus, Viral Nonstructural Proteins, Virus Replication, Antiviral Agents, Article, Cell Line, LarI, luciferase assay reagent 1, Virology, Humans, Protease Inhibitors, TPCK, tosyl phenylalanine chloromethyl ketone, Epoxide, Pharmacology, Hepatitis C virus, virus diseases, SGR, subgenomic replicon, biochemical phenomena, metabolism, and nutrition, GdnHCl, guanidine hydrochloride, JFH1, Japanese Fulminant Hepatitis 1, Cysteine Endopeptidases, NS, non-structural, DTT, dithiothreitol, HCV, hepatitis C virus, IMAC, immobilised metal ion affinity chromatography, ffLuc–NPT, firefly luciferase–neomycin phosphotransferase, Epoxy Compounds, RNA, Viral, Replicon, EC50, 50% effective concentration, CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulphonate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e91a51c623c1419a2d7daf2792b5cdc6Test

المؤلفون: Yanfei Qi, Juan Wang, Junqi Niu, Juan Li, Jinhua Li, Kun Xu, Yanfang Jiang, Enbo Wang, Ye Yuan, Hong Zhang, Yangguang Li, Shiyao Zhang

المصدر: Antiviral Research

مصطلحات موضوعية: HBsAg, SARS virus, medicine.disease_cause, Virus Replication, Cytopathogenic Effect, Viral, CC0, maximal noncytotoxic concentration, Chlorocebus aethiops, Adefovir, Hepatitis B e Antigens, Antiviral activity, virus diseases, food and beverages, ADV, adefovir dipivoxil, MDCK, Madin–Darby canine kidney, cccDNA, Hep G2 Cells, Hepatitis B, Tungsten Compounds, Hepatitis B Core Antigens, HBcAg, HBeAg, Severe acute respiratory syndrome-related coronavirus, Vero-E6, African green monkey kidney cells, TI, therapeutic index, EC50, 50% effective concentration, DMEM, Dulbecco’s Modified Eagle’s Medium, medicine.drug, Hepatitis B virus, Heteropolytungstate, EC90, 90% effective concentration, Microbial Sensitivity Tests, Biology, Antiviral Agents, Article, FBS, fetal bovine serum, In vitro, Virology, medicine, Animals, Humans, SARS, severe acute respiratory syndrome, CC50, 50% cytotoxic dose, Vero Cells, Pharmacology, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide, Hepatitis B Surface Antigens, fungi, POMs, Polyoxometalates, medicine.disease, digestive system diseases, HBV, hepatitis B virus, 3TC, nucleoside analog lamivudine, DNA, Viral, INF-α, interferon alpha

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af82afcdc90851a17390f390ca8ee259Test
http://europepmc.org/articles/PMC7114352Test

المؤلفون: David A. Oare, I-hung Shih, Laura S. Lehman, Erik De Clercq, Eric Mabery, Steven S. Bondy, Weidong Zhong, Inge Vliegen, Matthew Paulson, Johan Neyts, Gerhard Pürstinger, Hans Reiser, Jan Paeshuyse, Nina Boddeker, Tine De Burghgraeve, William A. Lee

المصدر: Journal of Hepatology

مصطلحات موضوعية: Carcinoma, Hepatocellular, Pyridines, RNA-dependent RNA polymerase, HCV RdRp inhibitor, Viral clearance, Hepacivirus, Virus Replication, CC50, 50% cytotoxic concentration, Antiviral Agents, Virus, Article, Cell Line, Tumor, Ribavirin, Humans, Protease inhibitor (pharmacology), Protease Inhibitors, Replicon, RdRp, RNA-dependent RNA polymerase, Polymerase, Subgenomic mRNA, Hepatology, biology, Liver Neoplasms, Imidazoles, virus diseases, Virology, digestive system diseases, Non-nucleoside, HCVcc, cell culture–grown chimeric HCV, Viral replication, Combination, biology.protein, RNA, Viral, EC50, 50% effective concentration, Interferons, 2′-C-MeCyt, 2′-C-methylcytidine, Nucleoside

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034b0a9d32ab3e902fed4fe6a8554f20Test
http://europepmc.org/articles/PMC7114863Test

المؤلفون: Joseph, Shaw, Mark, Harris, Colin W G, Fishwick

المصدر: Antiviral Research

مصطلحات موضوعية: Models, Molecular, NS2, Autoprotease, DAA, direct acting antiviral, viruses, Hepacivirus, Cysteine Proteinase Inhibitors, Viral Nonstructural Proteins, Virus Replication, Antiviral Agents, Article, Small Molecule Libraries, HCV, Hepatitis C virus, Structure-Activity Relationship, LarI, luciferase assay reagent 1, Catalytic Domain, Cell Line, Tumor, Humans, PLB, Passive Lysis Buffer, Hepatitis C virus, virus diseases, SGR, subgenomic replicon, biochemical phenomena, metabolism, and nutrition, Hepatitis C, Cysteine Endopeptidases, JFH1, Japanese Fulminant Hepatitis 1, NS, non-structural, Small molecule inhibitor, EC50, 50% effective concentration, Oligopeptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::1c3e79a9f42b9140263ceda193b8ba5dTest
https://pubmed.ncbi.nlm.nih.gov/26518228Test