المؤلفون: Kazuyuki Kasahara, Tzu Wen L. Cross, Federico E. Rey

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 15, Iss, Pp 70-81 (2018)

مصطلحات موضوعية: 0301 basic medicine, ER, estrogen receptor, FCG, four core genotypes, Metabolic disease, Physiology, Review, Disease, Type 2 diabetes, E2, estradiol, Gut flora, HDL-c, high-density lipoprotein cholesterol, SHP, small heterodimer partner, 0302 clinical medicine, GPR30, G protein-coupled receptor 30, Gonadal Steroid Hormones, Testosterone, ApoE, apolipoprotein E, Metabolic Syndrome, E3, estriol, Sex Characteristics, TMA, trimethylamine, High prevalence, IBD, inflammatory bowel disease, biology, LDL-c, low-density lipoprotein cholesterol, Cardiovascular disease, GI, gastrointestinal, E1, estrone, CVD, cardiovascular diseases, 3. Good health, Cardiovascular Diseases, Steroids, ZO-1, zonula occludens, T1D, type 1 diabetes, NOD, non-obese diabetic, MUC2, mucin-2, lcsh:Internal medicine, IBS, irritable bowel syndrome, T2D, type 2 diabetes, Gut microbiota, 03 medical and health sciences, FXR, farnesoid X receptor, TUDCA, tauroursodeoxycholic acid, Sex differences, medicine, Animals, Humans, lcsh:RC31-1245, Molecular Biology, Myocardium, BAs, bile acids, TLR4, Toll-like receptor 4, Cell Biology, medicine.disease, biology.organism_classification, Obesity, Gut microbiome, Gastrointestinal Microbiome, Sexual dimorphism, 030104 developmental biology, FMO3, flavin monooxygenases 3, LPS, lipopolysaccharides, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26b129281e97360a1e8ea4806d3c7e1Test
https://doi.org/10.1016/j.molmet.2018.05.016Test

المؤلفون: Carien L. van der Berg, Francois H. van der Westhuizen, Elardus Erasmus, Gerda Venter

المساهمون: 10213503 - Van der Westhuizen, Francois Hendrikus, 12253936 - Venter, Gerda, 10066136 - Erasmus, Elardus, 23491639 - Van der Berg, Carien L.

المصدر: Data in Brief
Data in Brief, Vol 29, Iss, Pp-(2020)

مصطلحات موضوعية: medicine.drug_class, E1, Estrone, Metabolite, E3, Estriol, Urine, Fractionation, lcsh:Computer applications to medicine. Medical informatics, ESI, Electrospray ionisation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, MS/MS, Tandem mass spectrometry, Biochemistry, Genetics and Molecular Biology, E2, Estradiol, medicine, Solid phase extraction, SPE, Solid phase extraction, LC-MS/MS, lcsh:Science (General), M, Methyl conjugation, 030304 developmental biology, MS, Mass spectrometry, G, Glucuronide conjugation, 0303 health sciences, Multidisciplinary, Chromatography, Estrogen metabolism, S, Sulphate conjugation, Elution, Chemistry, LC, Liquid chromatography, OH, Hydroxy, MeOH, Methanol, Metabolic pathway, v/v, Volume/volume ratio, Estrogen, lcsh:R858-859.7, Glucuronide, 030217 neurology & neurosurgery, lcsh:Q1-390, Method optimisation

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7efb1acbc210900ca9e0aa03eac1deTest
https://www.sciencedirect.com/science/article/pii/S2352340920301165Test

المؤلفون: Natalie Z.M. Homer, Francine Durocher, Ruth Andrew, Nina Denver, Brigitte Poirier, Caroline Diorio, Mélissa Pelletier, Sofia Laforest, Brian R. Walker, André Tchernof, Sébastien Nguyen

المصدر: Laforest, S, Pelletier, M, Denver, N, Poirier, B, Nguyen, S, Walker, B R, Durocher, F, Homer, N Z M, Diorio, C, Tchernof, A & Andrew, R 2019, ' Simultaneous quantification of estrogens and glucocorticoids in human adipose tissue by liquid-chromatography-tandem mass spectrometry ', Journal of Steroid Biochemistry and Molecular Biology, vol. 195, 105476 . https://doi.org/10.1016/j.jsbmb.2019.105476Test
The Journal of Steroid Biochemistry and Molecular Biology

مصطلحات موضوعية: 0301 basic medicine, HPLC, High-performance liquid chromatography, MPPZ, 1-(2,4-dinitro-phenyl)-4,4-dimethylpiperazinium, Hydrocortisone, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Adipose, Clinical Biochemistry, Adipose tissue, 13C3-E2, 2,3,4-[13C3]-17β-estradiol, Biochemistry, RSD, Relative standard deviation, Cortisol, DCM, Dichloromethane, SPE, Solid-phase extraction, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, E2, Estradiol, LLE, Liquid-liquid extraction, LOQ, Limit of quantitation, Receptor, LOD, Limit of detection, chemistry.chemical_classification, Estradiol, Chemistry, FA, Formic acid, EtOH, Ethanol, IS, Internal standards, LC–MS/MS, Liquid chromatography-tandem mass spectrometry, OFN, Oxygen-free nitrogen, E, Cortisone, Derivatization, 3. Good health, Adipose Tissue, Et2O, Diethyl ether, 030220 oncology & carcinogenesis, Molecular Medicine, lipids (amino acids, peptides, and proteins), Female, hormones, hormone substitutes, and hormone antagonists, inorganic chemicals, GC–MS/MS, Gas chromatography-tandem mass spectrometry, Spectrometry, Mass, Electrospray Ionization, RM, Estrone, E1, Estrone, UHPLC, Ultra-high-performance liquid chromatography, Breast Neoplasms, Article, Steroid, 03 medical and health sciences, EtOAc, Ethyl acetate, medicine, Humans, D4-F, 9,11,12,12-[2H4]-cortisol, Glucocorticoids, Molecular Biology, Detection limit, 13C3-E1, 2,3,4-[13C3]-estrone, Chromatography, organic chemicals, RME, Relative mean error, MTBE, Methyl t-butyl ether, PPZ, 1-(2,4-dinitro-5-fluorophenyl)-4-methylpiperazine, technology, industry, and agriculture, SNR, Signal-to-noise ratio, Estrogens, Cell Biology, QR, Cortisone, MeOH, Methanol, 030104 developmental biology, Enzyme, ESI, Electrospray ionization, MRM, Multiple reaction monitoring, Chromatography, Liquid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f0ee7bebfa1d074106d9769c356fedTest
https://eprints.gla.ac.uk/202274/1/202274.pdfTest

المؤلفون: Nele Friedrich, Brian G. Keevil, Henry Völzke, Matthias Nauck, Anke Hannemann, Robin Haring, Konrad Pätzug, Hanna Kische

المصدر: Bone Reports
Pätzug, K, Friedrich, N, Kische, H, Hannemann, A, Völzke, H, Nauck, M, Keevil, B G & Haring, R 2017, ' Sex hormones and quantitative ultrasound parameters at the heel in men and women from the general population ', Bone Reports, vol. 7, pp. 51-56 . https://doi.org/10.1016/j.bonr.2017.08.003Test
Bone Reports, Vol 7, Iss C, Pp 51-56 (2017)

مصطلحات موضوعية: 0301 basic medicine, LC-MS, liquid chromatography-mass spectrometry, lcsh:Diseases of the musculoskeletal system, Heel, Endocrinology, Diabetes and Metabolism, Osteoporosis, FT, free testosterone, chemistry.chemical_compound, 0302 clinical medicine, Sex hormone-binding globulin, Orthopedics and Sports Medicine, Sex hormones, Testosterone, ANOVA, analysis of variance, education.field_of_study, biology, SHIP, Study of Health in Pomerania, SHBG, sex hormone-binding globulin, SI, stiffness index, E1, estrone, QUS, quantitative ultrasound, medicine.anatomical_structure, Study of Health in Pomerania, Analysis of variance, medicine.medical_specialty, DHEAS, Population, BMD, bone mineral density, 030209 endocrinology & metabolism, Estrone, Article, ASD, androstenedione, BUA, broadband ultrasound attenuation, 03 medical and health sciences, Internal medicine, medicine, Stiffness index, DHEAS, dehydroepiandrosterone sulphate, education, Bone, SE, standard error, business.industry, TT, testosterone, medicine.disease, CI, confidence interval, 030104 developmental biology, Endocrinology, chemistry, biology.protein, SOS, speed of sound, lcsh:RC925-935, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c536afdb4df8a3c0fd033886119ef05cTest
http://europepmc.org/articles/PMC5574814Test

المؤلفون: Ruth Andrew, Shazia Khan, Margaret R. MacLean, Nina Denver, Natalie Z.M. Homer

المصدر: The Journal of Steroid Biochemistry and Molecular Biology
Denver, N, Khan, S, Homer, N, MacLean, M & Andrew, R 2019, ' Current strategies for quantification of estrogens in clinical research ', Journal of Steroid Biochemistry and Molecular Biology . https://doi.org/10.1016/j.jsbmb.2019.04.022Test

مصطلحات موضوعية: Biomedical Research, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Clinical Biochemistry, FA/D-IMS, field asymmetric/differential- ion mobility mass spectrometry, Extraction, Urine, Pharmacology, E2, estradiol, EOC, ethoxycarbonlyation, HFB, heptafluorobutyryl chloride, 01 natural sciences, Biochemistry, 2,4 or 16-OHE1, 2, 4 or 16-hydroxestrone, TQ-S, tandem quadrupole mass spectrometry, chemistry.chemical_compound, Endocrinology, Liquid chromatography–mass spectrometry, Tandem Mass Spectrometry, IS, internal standard, CI, chemical ionization, 0303 health sciences, PED, N’-(5-fluoro-2,4-dinitrophenyl)-N,N-dimethyl-1,2- ethanediamine, medicine.diagnostic_test, MPPZ, 1-(2, 4-dinitrophenyl)-4,4-di- methylpiperazinium, APCI, atmospheric pressure chemical ionization, 16epiOHE2, 16β-hydroxy-17β-estradiol, 2,4 or 16-OHE2, 2, 4 or 16-hydroxestradiol, COMT, catechol-O-methyltransferase, NS, Not stated, E1, estrone, Derivatization, 3. Good health, 2 or 4-MeOE2, 2 or 4-methoxyestradiol, DS, dansyl chloride, BMP, 3-bromomethyl-propyphenazone, APZ, 4-(4-methyl-1-piperazyl)-3-nitrobenzoyl azide, SPE, solid phase extraction, 17epiOHE2, 16α-hydroxy-17α-estradiol, LLE, Liquid Liquid Extraction, Molecular Medicine, CYP, cytochrome P450, PFBO, perfluorobenzoyl chloride, P, picolinoyl carboxylate, FMP, 2-fluoro-1-methyl-pyridinium p-toluene sulfonate, RM, Gas chromatography tandem mass spectrometry, medicine.drug_class, PDFO, pentadecafluorooctanoyl chloride, PS, pyridine-3-sulfonyl chloride, Estrone, IMS, ion mobility mass spectrometry, MSTFA, N-methyl-N-(trimethylsilyl)-trifluoroacetamide, PFBHA, pentaflurobenzoyl hydroxylamine hydrochloride, 2OHE-3ME, 2-hydroxyestrone-3-methyl ether, TW-IMS, travelling wave-ion mobility mass spectrometry, Article, Steroid, 03 medical and health sciences, NBCOCL, 4-nitrobenzoyl chloride, TFA, trifluoracetic acid, DT-IMS, drift tube-ion mobility mass spectrometry, medicine, Humans, 16ketoOHE2, 16-oxo-17β-estradiol, Molecular Biology, 030304 developmental biology, MIS, methylimidazole-2-sulfonyl chloride, DNBF, 2,4-dinitrofluorobenzene, TMSI, N-(trimethylsilyl)imidazole, Gas Chromatography/Tandem Mass Spectrometry, C1-NA-NHS, N-methyl-nicotinic acid N-hydroxysuccinimide ester, 010401 analytical chemistry, PPZ, 1-(2,4-dinitro-5-fluorophenyl)-4-methylpiperazine, OHE, hydroxyestrogens, Estrogens, Cell Biology, 17βHSD1 and 17βHSD2, 17beta-hydroxysteroid dehydrogenase type 1 & 2, 2 or 4-MeOE1, 2 or 4-methoxyestrone, Estrogen, 0104 chemical sciences, LC–MS/MS, liquid chromatography tandem mass spectrometry, UFLC, ultraflow LC, chemistry, Immunoassay, DMIS, 1,2-dimethylimidazole-5-sulfonyl chloride, Liquid chromatography tandem mass spectrometry, NMPS, N-methyl pyridinium-3-sulfonyl chloride, APPI, atmospheric pressure photoionization, Chromatography, Liquid, GC–MS/MS, gas chromatography tandem mass spectrometry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048fb910678af3f142af66b929ca3ed9Test
https://pubmed.ncbi.nlm.nih.gov/31112747Test

المؤلفون: Nina, Denver, Shazia, Khan, Ioannis, Stasinopoulos, Colin, Church, Natalie Zm, Homer, Margaret R, MacLean, Ruth, Andrew

المصدر: Analytica Chimica Acta

مصطلحات موضوعية: LC-MS, liquid chromatography-mass spectrometry, Estrogen metabolites, cps, counts per second, IS, internal standards, CID, collision-induced dissociation, RSD, relative standard deviation, Article, LLOQ/ULOQs, lower/upper limits of quantitation, Limit of Detection, Tandem Mass Spectrometry, LODs, limits of detection, PPZ, 1-(5-fluoro-2,4-dinitrophenyl)-4-methylpiperazine, MeOE1/2, methoxyestr-one/adiol, Humans, RME, relative mean error, Methylpiperazine, Piperazine, FA, formic acid, ESI, electrospray ionization, MPPZ, methyl-PPZ, Solid Phase Extraction, LC-MS/MS, liquid chromatography tandem mass spectrometry, SNR, signal/noise, OHE1/2, hydroxyestr-one/adiol, Estrogens, Derivatization, Estrogen, E1, estrone, SPE, solid phase extraction, Liquid chromatography tandem mass spectrometry, Linear Models, PAH, pulmonary arterial hypertension, SD, standard deviation, Blood Chemical Analysis, Chromatography, Liquid, MRM, multiple reaction monitoring

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::6c42c2feaf6bb5dd75f9640cfc27c83eTest
https://pubmed.ncbi.nlm.nih.gov/30712596Test

المؤلفون: Lina, Schiffer, Wiebke, Arlt, Karl-Heinz, Storbeck

المصدر: Molecular and Cellular Endocrinology

مصطلحات موضوعية: A4, androstenedione (androst-4-ene-3,17-dione), HSD, hydroxysteroid dehydrogenase, PROG, progesterone, PORD, cytochrome P450 oxidoreductase deficiency, E2, estradiol, urologic and male genital diseases, STS, steroid sulfatase, StAR, steroidogenic acute regulatory protein, 11-oxygenated androgens, Testosterone, DHEAS, dehydroepiandrosterone sulfate, T, testosterone (androst-4-ene-17β-ol-3-one), DHEA, dehydroepiandrosterone (androst-5-ene-3β-ol-17-one), Reproduction, PREG, pregnenolone, SHBG, sex hormone-binding globulin, 11KA4, 11-keto-androstenedione, 11OHT, 11β-hydroxy-testosterone, EpiT, epitestosterone (17α-hydroxy-testosterone, androst-4-ene-17α-ol-3-one), Intracrinology, E1, estrone, EpiAST, 5α-androstan-3β-ol-17-one, 11OHA4, 11β-hydroxy-androstenedione, 17OHPROG, 17α-hydroxy-progesterone, Organ Specificity, PAPS, 3′-phospho-adenosine-5′-phosphosulfate, Androgens, CYP, cytochrome P450, Steroids, 11KDHT, 11-keto-5α-dihydrotestosterone, Steroid biosynthesis, AST, androsterone (5α-androstan-3α-ol-17-one), SULT, sulfotransferase, 11OHDHT, 11β-hydroxy-5α-dihydrotestosterone, 17αHP, 5α-pregnane-17α-ol-3,20-one, Article, Pdiol, 5α-pregnane-3α,17α-diol-20-one, Animals, Humans, UGT, uridine diphosphate-glucuronosyl transferase, CRPC, castration resistant prostate cancer, CHOL, cholesterol, DHT, 5α-dihydrotestosterone (5α-androstan-17β-ol-3-one), 3α-adiol, 5α-androstan-3α,17β-diol, OATP, organic anion-transporting polypeptide, 5α-dione, 5α-androstane-3,17-dione, AKR, aldo-keto reductase, 5-diol, androst-5-ene-3β,17β-diol, ETIO, etiochonanolone (5β-androstan-3α-ol-17-one), Biosynthetic Pathways, E1S, estrone sulfate, Hormone-dependent cancer, AR, androgen receptor, 11KT, 11-keto-testosterone, PCOS, polycystic ovary syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::5107efbc47e71ea8aa284d5bb9b96645Test
https://pubmed.ncbi.nlm.nih.gov/28865807Test

المؤلفون: Faqehi, Abdullah M.M., Cobice, Diego F., Naredo, Gregorio, Mak, Tracy C.S., Upreti, Rita, Gibb, Fraser W., Beckett, Geoffrey J., Walker, Brian R., Homer, Natalie Z.M., Andrew, Ruth

المصدر: Faqehi, A M, Cobice, D F, Naredo, G, Mak, T C, Upreti, R, Gibb, F W, Beckett, G J, Walker, B R, Homer, N Z M & Andrew, R 2016, ' Derivatization of estrogens enhances specificity and sensitivity of analysis of human plasma and serum by liquid chromatography tandem mass spectrometry ', Talanta, vol. 151, pp. 148–156 . https://doi.org/10.1016/j.talanta.2015.12.062Test
Talanta

مصطلحات موضوعية: 17αE2, 17α-estradiol, Male, LC-MS, liquid chromatography-mass spectrometry, Chemistry(all), cps, counts per second, IS, internal standards, CID, collision-induced dissociation, RSD, relative standard deviation, Pyridinium Compounds, E2, estradiol, LODs, limits of detection, Tandem Mass Spectrometry, TEA, triethylamine, 3,4-[13C2E1, 3,4-[13C]2-estrone, FA, formic acid, FMP-TS, 2-fluoro-1-methylpyridinium-p-toluenesulfonate, Aged, 80 and over, LOQs, limits of quantitation, ESI, electrospray ionization, UHPLC, ultra high performance liquid chromatography, Estradiol, APCI, atmospheric pressure chemical ionization, Benzenesulfonates, Solid Phase Extraction, d4E1, 2,4,16,16-[2H]4-estrone, MD, mean difference, Middle Aged, E1, estrone, Derivatization, MRM, multiple reactions monitoring, Postmenopause, SPE, solid phase extraction, HPLC, high performance liquid chromatography, Female, d4E2, 2,4,16,16-[2H]4-estradiol, Adult, Spectrometry, Mass, Electrospray Ionization, Estrone, Liquid chromatography, Article, Young Adult, Humans, RME, relative mean error, Aged, D, difference, Mass spectrometry, LC-MS/MS, liquid chromatography tandem mass spectrometry, SNR, signal/noise, Reproducibility of Results, Estrogens, 13C2E2, 3,4-[13C]2-estradiol, Premenopause, Methylpyridinium ether, SD, standard deviation, Chromatography, Liquid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aef06375c6cdf233b6b9a509f2a2f89cTest