المؤلفون: Pratool Bharti, Prajkta Chivte, Elizabeth R. Gaillard, Venkata Devesh Reddy Seethi, Shrihari S. Kadkol, Zane LaCasse, Joshua Bland

المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 31-41 (2021)

مصطلحات موضوعية: Saliva, Diagnostic methods, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Concordance, Clinical Biochemistry, IgG, immunoglobulin G, N Protein, nucleocapsid protein, Immunoglobulins, MALDI-ToF MS, matrix-assisted laser desorption/ionization-time of flight mass spectrometry, COVID-19 testing, ACE2, angiotensin-converting enzyme 2, IgA, immunoglobulin A, Microbiology, S Protein, spike protein, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, M Protein, membrane protein, AUC, area under the curve, RBD, receptor binding domain, EUA, emergency use authorization, Medical technology, Medicine, R855-855.5, Spectroscopy, COVID-19, coronavirus disease 2019, MALDI-ToF, LoD, limit of detection, LC-MS, liquid chromatography mass spectrometry, business.industry, Ct, cycle threshold, DTT, dithiothreitol, VEP, viral envelope protein, Asymptomatic, Protein profiling, Medical Laboratory Technology, IgM, immunoglobulin M, FDA, food and drug administration, Potential biomarkers, Proteome, Immunology, RNA, ribonucleic acid, E Protein, envelope protein, WHO, world health organization, ROC, receiver operating characteristic, RT-qPCR, reverse transcriptase quantitative polymerase chain reaction, business, NP, nasopharyngeal, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577dd0efd6335d910041863dffc117eeTest
http://europepmc.org/articles/PMC8426322Test

المؤلفون: Esperanza Hernández-Carralero, Yeray Hernández-Reyes, Elisa Cabrera, Maria Cristina Paz-Cabrera, Raimundo Freire, Miriam Hernández-Porto, Veronique A. J. Smits, Eduardo Salido, Juan Ramon Hernandez-Fernaud, David A. Gillespie

المصدر: Biochemical and Biophysical Research Communications

مصطلحات موضوعية: 0301 basic medicine, Coronavirus M Proteins, Myeloma protein, viruses, Immunoblotting, Biophysics, NTD N-terminal Domain, RBD Receptor Binding Domain, Dot blot, SARS-CoV-2 Severe acute respiratory syndrome corona virus 2, S protein Spike protein, Spike protein, medicine.disease_cause, Biochemistry, Article, Virus, Epitope, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Coronavirus Nucleocapsid Proteins, Humans, E protein Envelope protein, LKR Serine-rich linker region, Molecular Biology, Coronavirus, Nucleocapsid protein, M protein Membrane protein, N protein Nucleocapsid protein, biology, SARS-CoV-2, Immune Sera, Virion, COVID-19, Cell Biology, Phosphoproteins, Acquired immune system, Virology, Immunity, Humoral, 030104 developmental biology, Immunoglobulin G, Membrane protein, 030220 oncology & carcinogenesis, Spike Glycoprotein, Coronavirus, biology.protein, Immunotest, COVID-19 Coronavirus disease 2019, CTD C-terminal Domain, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f57468b59699a01e6a9b2d74092e2bdTest
https://doi.org/10.1016/j.bbrc.2021.01.073Test

المؤلفون: Seyed Shahabeddin Mortazavi-Jahromi, Abbas Mirshafiey, Mona Aslani

المصدر: International Immunopharmacology

مصطلحات موضوعية: RhoB, Ras homolog gene family member B, M-CSF, Macrophage CSF, PPP2CA, Protein phosphatase 2 catalytic subunit alpha, RNA pol, RNA polymerase, medicine.medical_treatment, IRF, IFN regulatory factor, v-miRNA, Viral miRNA, DCs, Dendritic cells, MyD88, Myeloid differentiation factor 88, ISGs, IFN-stimulated genes, TLRs, Toll-like receptors, AT1R, Ang II receptor type 1, KCNQ1OT1, KCNQ1 overlapping transcript 1, CYLD, Cylindromatosis, IFNs-I, Type I IFNs, TNF-α, Tumor necrosis factor alpha, cPLA2, Cytoplasmic phospholipase A2, LPS, Lipopolysaccharide, Th cells, T helper cells, LPLs, Lysophospholipids, NLRP3, NOD-, LRR- and pyrin domain-containing protein 3, siRNAs, Small interfering RNAs, CNS, Central nervous system, pri-miRNAs, Primary miRNAs, MDA5, Melanoma differentiation-associated protein 5, ERK, Extracellular signal-regulated kinase, MERS-CoV, Middle East respiratory syndrome coronavirus, BBB, Blood-brain barrier, OxPLs, Oxidized phospholipids, MODS, Multiple organ dysfunction syndrome, mPGES-1, Microsomal prostaglandin E synthase-1, RNAi, RNA interference, ADAM17, A disintegrin and metalloproteinase 17, AGO, Argonaute, CRISPR, Cas13 family of clustered regularly interspaced short palindromic repeats, DAMPs, Damage-associated molecular patterns, circRNAs, Circular RNAs, CD, Cluster of differentiation, JAK, Janus kinase, TNFR, TNF receptor, Cytokine Release Syndrome, TRIM27, Tripartite motif-containing protein 27, gp130, Glycoprotein 130, MMP, Matrix metalloproteinase, 2019-nCoV, 2019 novel coronavirus, CCL, C-C motif chemokine ligand, SOCS3, Suppressor of cytokine signaling 3, Immunology, COX, Cyclooxygenase, Sry, Sex-determining region Y, Article, S protein, Spike protein, microRNA, Humans, K, Lysine, CSF, Colony-stimulating factor, RGMB-AS1, RGMB antisense RNA 1, TIMP-I, Tissue inhibitors of matrix metalloproteinases-I, S100A9, S100 calcium-binding protein A9, Pharmacology, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, NOXs, Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, CHD, Coronary heart disease, STAT, Signal transducer and activator of transcription, Virus Internalization, medicine.disease, Viral replication, NF-κB, Nuclear factor kappa-light-chain-enhancer of activated B cells, miRNAs-based therapy, TBK1, TANK-binding kinase 1, ORF, Open reading frame, SOFA, Sequential organ failure assessment score, lncRNAs, Long non-coding RNAs, CatB/L, Cathepsin B/L, sIL-6R, Soluble IL-6R, ROS, Reactive oxygen species, EAE, Experimental autoimmune encephalomyelitis, RBCs, Red blood cells, MAPK, Mitogen-activated protein kinase, PBMCs, Peripheral blood mononuclear cells, N protein, Nucleocapsid protein, Ig, Immunoglobulin, Cytokine storm, Bioinformatics, Virus Replication, 3'-UTR, 3'-untranslated region, H3, Histone 3, AGEs, Advanced glycation end products, Renin-Angiotensin System, XPO5, Exportin-5, G-CSF, Granulocyte CSF, CXCL, C-X-C motif chemokine ligand, DIC, Disseminated intravascular coagulation, Immunology and Allergy, IL, Interleukin, PG, Prostaglandin, RAS, Renin-Angiotensin system, Amp, Amplifier, MCs, Mast cells, COVID-19, Coronavirus disease 2019, HSP, Heat shock protein, AA, Arachidonic acid, ASOs, Antisense oligonucleotides, IFN, Interferon, mRNA, Messenger RNA, ICU, Intensive care unit, Cytokine, RAGE, Receptor for advanced glycation end products, mIL-6R, Membrane IL-6 receptor, FOXO3, Forkhead box O3, miRNAs, LTs, Leukotrienes, miRISC, MicroRNA-induced silencing complex, IκB-ζ, Inhibitor of nuclear factor kappa B zeta, Signal transduction, me3, Trimethylation, M protein, Membrane protein, APJ, Apelin receptor, AP-1, Activator protein 1, TMPRSS2, Transmembrane serine protease 2, PRR, Pattern recognition receptor, GM-CSF, Granulocyte-macrophage CSF, RIG-I, Retinoic acid-inducible gene I, E protein, Envelope protein, Biology, hsa, Homo sapiens, TXs, Thromboxanes, LOXs, Lipoxygenases, Virus, ER, Endoplasmic reticulum, ARDS, Acute respiratory distress syndrome, Gene regulators, medicine, me2, Dimethylation, Animals, PKCα, Protein kinase C alpha, pre-miRNAs, Precursor miRNAs, DMVs, Double membrane vesicles, ceRNAs, Competing endogenous RNAs, nsp, Non-structural protein, Competing endogenous RNA, SARS-CoV-2, ALI, Acute lung injury, PaO2/FiO2, Pressure of arterial oxygen to fractional inspired oxygen concentration, COVID-19, ACE, Angiotensin-converting enzyme, ANRIL, Antisense noncoding RNA in the INK4 locus, miRNAs, MicroRNAs, MEG3, Maternally expressed gene 3, Review article, MicroRNAs, DMD, Dense matted deposits, TAB, Transforming growth factor β-activated kinase-1 (TAK1)-binding protein, HMGB1, High mobility group box protein 1, Ang, Angiotensin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4706f42d886bb679ed2a6b85453a9cTest
https://pubmed.ncbi.nlm.nih.gov/34601331Test

المؤلفون: Kalyan Ghosh, Sk. Abdul Amin, Suvankar Banerjee, Tarun Jha, Shovanlal Gayen

المصدر: Bioorganic & Medicinal Chemistry

مصطلحات موضوعية: Peptidomimetic, viruses, medicine.medical_treatment, CoV, coronavirus, Clinical Biochemistry, Drug Evaluation, Preclinical, Quantitative Structure-Activity Relationship, Pharmaceutical Science, medicine.disease_cause, 01 natural sciences, Biochemistry, chemistry.chemical_compound, S protein, spike protein, Catalytic Domain, Drug Discovery, Coronavirus 3C Proteases, COVID-19, coronavirus disease 2019, Coronavirus, media_common, chemistry.chemical_classification, E protein, envelope protein, PLpro, papain-like protease, Molecular Structure, Chemistry, Drug discovery, MERS-CoV, Middle East respiratory syndrome coronavirus, SPCI, Structural and physico-chemical interpretation, Molecular Docking Simulation, PLpro, Molecular Medicine, EBOV, Ebola virus, Structure-activity relationship (SAR), Mpro, Protein Binding, Drug, media_common.quotation_subject, SARS-CoV, severe acute respiratory syndrome coronavirus, Computational biology, Cysteine Proteinase Inhibitors, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Antiviral Agents, Article, WHO, World Health Organization, ORF, open reading frame, SAR, Structure-activity relationship, medicine, M protein, membrane protein, NTD, N-terminal domain, RdRp, RNA-dependent RNA polymerase, Molecular Biology, ComputingMethodologies_COMPUTERGRAPHICS, Protease, SARS-CoV-2, 010405 organic chemistry, Organic Chemistry, COVID-19, Nsp, non-structural proteins, N protein, nucleocapsid protein, QSAR, Quantitative structure-activity relationship, 0104 chemical sciences, Mpro, main protease, 010404 medicinal & biomolecular chemistry, Papain, Enzyme, Non-covalent inhibitor, 3CLpro, 3C-like protease or main protease, Viral replication

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f26a82842660cdbaac04e5441c54ccTest

المؤلفون: Jee Young Chung, Young Jik Kwon, Melissa N. Thone

المصدر: Advanced Drug Delivery Reviews

مصطلحات موضوعية: Vaccine delivery, and promotion of well-being, Emergency Use Authorization, MSCs, mesenchymal stem cells, Type 1 IFNs, Type 1 interferons, Pharmaceutical Science, MERS, Middle East respiratory syndrome coronavirus, 02 engineering and technology, Disease, S protein, spike protein, Pandemic, Severe acute respiratory syndrome coronavirus 2, Medicine, Pharmacology & Pharmacy, Lung, NK cell, natural killer cell, CDC, Centers for Disease Control and Prevention, media_common, COVID-19, coronavirus disease 2019, NTD, N-terminal binding domain, 0303 health sciences, Coronavirus disease 2019, Genetically modified virus, AD, adenovirus, Toll-like receptor, TLR, ADE, antibody-dependent enhancement, Severe acute respiratory syndrome coronavirus, Pharmacology and Pharmaceutical Sciences, 021001 nanoscience & nanotechnology, Vaccination, Infectious Diseases, 3.4 Vaccines, 5.1 Pharmaceuticals, SARS, severe acute respiratory syndrome coronavirus, Pneumonia & Influenza, Development of treatments and therapeutic interventions, Infection, 0210 nano-technology, EUA, Emergency Use Authorization, Biotechnology, Drug, CTLs, cytotoxic T lymphocytes, COVID-19 Vaccines, media_common.quotation_subject, E protein, Envelope protein, Neutralizing antibodies, ACE2, angiotensin-converting enzyme 2, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Antiviral Agents, Article, WHO, World Health Organization, Vaccine Related, DC, dendritic cell DC, 03 medical and health sciences, RBD, receptor binding domain, Immune system, Drug Development, Immunity, Biodefense, AD, AAV, adeno-associated virus, Animals, Humans, M protein, membrane protein, Immune response, ARDS, acute respiratory distress syndrome, 030304 developmental biology, TMPRSS2, transmembrane protease serine, business.industry, Immunization Programs, SARS-CoV-2, Prevention, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19, Pneumonia, Prevention of disease and conditions, PPRs, pattern recognition receptors, N protein, nucleocapsid protein, Coronavirus disease 2019 (COVID-19), Emerging Infectious Diseases, Good Health and Well Being, Immunology, Immunization, APC, Antigen presenting cell, LNPs, lipid nanoparticles, RSV, respiratory syncytial virus, FDA, U.S Food and Drug Administration, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2fddd3e0cdb765800a656287283f84Test
http://europepmc.org/articles/PMC7759095Test

المؤلفون: Chunmei Zhu, Fei Sun, Guoliang Zhu, Yun Zhu

المصدر: Current Research in Microbial Sciences
Current Research in Microbial Sciences, Vol 1, Iss, Pp 53-61 (2020)

مصطلحات موضوعية: 3CLpro, 3C-like protease, MERS-CoV, the Middle Eastern respiratory syndrome coronavirus, medicine.medical_treatment, viruses, 6-HB, six-helix bundle, lcsh:QR1-502, N protein, Nucleocapsid protein, sgRNA, subgenomic RNA, medicine.disease_cause, lcsh:Microbiology, Drug-screening, Pandemic, HR1, heptad repeat 1, skin and connective tissue diseases, General Environmental Science, Coronavirus, Genomic organization, COVID-19, coronavirus disease 2019, CatB/L, cysteine proteases-cathepsin B and L, HR2, heptad repeat 2, RMP, The remdesivir monophosphate, RBM, receptor-binding motif, virus diseases, RBD, receptor-binding domain, gRNA, genomic RNA, NSP, non-structural proteins, Pneumonia (non-human), M protein, Membrane protein, Genome-encoded proteins, lcsh:QH426-470, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV, severe acute respiratory syndrome coronavirus, PD, peptidase domain, E protein, Envelope protein, Biology, ACE2, angiotensin-converting enzyme 2, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Article, medicine, RdRp, RNA-dependent RNA polymerase, Protease, SARS-CoV-2, fungi, Structure-based screening, Outbreak, COVID-19, S protein, Spike glycoprotein, medicine.disease, Virology, respiratory tract diseases, body regions, lcsh:Genetics, Mpro, Main protease, ORF, Open reading frame, General Earth and Planetary Sciences

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c426bd40828aafcd5a1b1de6a6c34aTest
http://europepmc.org/articles/PMC7323663Test

المؤلفون: Shikha Mudgal, Ananya Pandit, Rohitash Yadav, Y. Sheena Mary, Hoineiting Rebecca Haokip

المصدر: Journal of the Indian Chemical Society

مصطلحات موضوعية: 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), viruses, RBD, Receptor binding domain, SARS CoV-2, N protein, Nucleocapsid protein, E protein, Envelope protein, Virus diseases, computer.software_genre, Genome, Article, RCT, Replication and Transcription Complex, Virus, Inorganic Chemistry, RdRp, RNA dependent RNA polymerase, Non-structural protein, Drug Discovery, Pandemic, Electrochemistry, ACE2, Angiotensin-Converting Enzyme 2, Physical and Theoretical Chemistry, S protein, Spike glycol protein, NS3, Point mutation, Database, Chemistry, Organic Chemistry, COVID-19, NSP, Non-structural protein, biochemical phenomena, metabolism, and nutrition, SARS-CoV-2, Severe acute respiratory syndrome corona virus 2, COVID-19, Corona virus disease 2019, M protein, Membrane protein, computer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2598c0a39c49c8054df944de8d8771Test
https://doi.org/10.1016/j.jics.2021.100156Test

المؤلفون: Hui Nan, Xiaodong Ren, Pengcheng Yu, Hong Liu, Qiao Guaiping, Wenqiang Cao, Liu Yuzhi, Ju Xingke, Li Han, Jia Minyi, Lei Tian, Li Juan, Liang Chengyuan

المصدر: Phytomedicine Plus
Phytomedicine Plus, Vol 1, Iss 2, Pp 100027-(2021)

مصطلحات موضوعية: Vero E6, African Green Monkey Kidney Epithelial-6, Huh-7, Human Hepatocellular Carcinoma-7, 3CLpro, 3C-like protease, HPLC, High-performance liquid chromatography, MOI, Multiplicity of infection, MERS, Middle east respiratory syndrome, AECOPD, Acute exacerbation of chronic obstructive pulmonary disease, Pharmacology, Other systems of medicine, IP-10, Interferon-inducible protein-10, Medicine, CCL-2/MCP-1, C-C motif ligand 2/monocyte chemoattractant protein-1, gp-130, Glycoprotein 130, HSV-1, Herpes simplex virus type 1, General Pharmacology, Toxicology and Pharmaceutics, qPCR, Quantitative PCR, media_common, MTT, Methyl Thiazolyl Tetrazolium, ERK, Extracellular signal-regulated kinase, CC50, 50% Cytotoxic concentration, IAV, Influenza A virus, HIV, Human immunodeficiency virus, mIL-6R, Membrane-bound form IL-6 Receptor, RSV, Respiratory syncytial virus, IL-8, Interleukin-8, Drug, media_common.quotation_subject, TCID50, 50% Tissue culture infective dose, COPD, Chronic obstructive pulmonary disease, Pharmacy, Article, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, HVJ, Hemagglutinating virus of Japan, medicine.disease, IBV, Influenza B virus, Clinical trial, CSS, Cytokine storm syndrome, Complementary and alternative medicine, RZ201-999, MIP-1β, Macrophage Inflammatory Protein-1β, IL-6R, IL-6 Receptor, MAPK, Mitogen-activated protein kinase, MOF, Multifunctional organ damage, AQP3, Aquaporins 3, PKA/p-CREB, Protein kinase A /phosphorylated cAMP response element-binding protein, nsps, Non-structural proteins, CXCL-10/IP-10, C-X-C Motif Chemokine Ligand 10/ Interferon Gamma-induced Protein 10, IFN-λ1, Interferon-λ1, Pandemic, PKB, Akt, Protein kinase B, ORFs, Open reading frames, CAT, COPD assessment test, COVID-19, Coronavirus disease 2019, Grb2, Growth factor receptor-bound protein 2, biology, LD50, 50% Lethal dose, TD50, Half-toxic dose, Cytokine storm syndrome (CSS), MLD50, 50% Minimum lethal dose, Hep-2, Human epithelial type 2, FBS, Fatal bovine serum, LH capsules, Forsythia honeysuckle (Lianhuaqingwen) capsules, CT, Computed tomography, NF-kB, Nuclear transcription factor kappa-B, M protein, Membrane protein, RT-PCR, Reverse transcription PCR, PLpro, Papain-like proteases, PI3K, Phosphoinositide 3-kinases, MDCK, Madin-darby canine kidney, Coronavirus disease 2019 (COVID-19), MCP-1, Monocyte chemotactic protein 1, PBS, Phosphate buffered saline, E protein, Envelope protein, RANTES, Regulated on activation normal T cell expressed and secreted, CPE, Cytopathic effect, PRC, People's Republic of China, Forsythia, MEK, Mitogen-activated protein kinase kinase, ACE2, Angiotensin-converting enzyme 2, ARDS, Acute respiratory distress syndrome, PHN, Phillyrin, IL-6, Interleukin-6, AIDS, Acquired immune deficiency syndrome, JAK/STAT, Janus kinase/signal transducers and activators of transcription, IC50, 50% Inhibition concentration, QC, Quality control, SARS-CoV-2, business.industry, Lianhuaqingwen, COVID-19, Forsythia honeysuckle (Lianhuaqingwen,LH) capsules, biology.organism_classification, CFDA, China Food and Drug Administration, JAK1/2, Janus kinase1/2, 3C-like protease (3CLpro), Ras, Ras GTPase, business, Cytokine storm, NHC, National Health Commission, TD0, Non-toxic Dose

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed6ee319ef2e397034c14aa22649908Test
https://doi.org/10.1016/j.phyplu.2021.100027Test