A short review of drug–food interactions of medicines treating overactive bladder syndrome
| العنوان: | A short review of drug–food interactions of medicines treating overactive bladder syndrome |
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| المؤلفون: | Danuta Owczarek, Tomasz Rodacki, Paweł Paśko, Renata Domagała-Rodacka |
| المصدر: | International Journal of Clinical Pharmacy |
| بيانات النشر: | Springer International Publishing, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, food.ingredient, Anticholinergic drugs, 030232 urology & nephrology, Urinary incontinence, Pharmaceutical Science, Pharmacy, Review Article, Review, Pharmacology, Toxicology, 030226 pharmacology & pharmacy, Grapefruit juice, Cholinergic Antagonists, 03 medical and health sciences, Food-Drug Interactions, 0302 clinical medicine, food, Internal medicine, medicine, Fesoterodine, Darifenacin, Nocturia, Humans, Pharmacology (medical), Oxybutynin, Solifenacin, business.industry, Urinary Bladder, Overactive, Fruit and Vegetable Juices, Treatment Outcome, Drugs–food interactions, Overactive bladder syndrome, Tolterodine, medicine.symptom, Mirabegron, business, medicine.drug |
| الوصف: | Background Overactive bladder syndrome is a condition where one or more of the symptoms such as pollakiuria, urgent need to urinate, nocturia and urinary incontinence is observed. Its prevalence ranges between 7 and 27 % in men and 9–43 % in women. The role of a pharmacist is to educate the patient on medications administration scheme, and drug interactions with particular food or food components. Aim of the review To assess a potential impact of food and fruit juice on the pharmacokinetic and therapeutic effects of medications used in treating overactive bladder syndrome. This information will enhance pharmaceutical care and is vital and helpful for pharmacists counseling their patients. Method In order to gather information on interactions of medications employed in bladder dysfunctions, the English language reports published in the PubMed, Embase, Cochrane and CINAHL database over the years 1996–2015 were studied. Additionally, other resources, namely drugs.com, Medscape, UpToDate, Micromedex, Medical Letter, as well as Stockley Drugs Interaction electronic publication were included in the study. The analysis also covered product data sheets for particular medicinal products. Results Meals and the consumption of grapefruit juice were found to exert a diversified effect on the pharmacokinetics of drugs employed in overactive bladder syndrome therapy. Neither tolterodine, nor mirabegron interact with food and citrus fruit juice, whereas darifenacin, fesoterodine, oxybutynin and solifenacin do interact with grapefruit and others citrus fruit juice. The effects of such interactions may potentially be negative to patients. Trospium absorption is significantly decreased by food. Conclusion For selected medicines used in treating bladder dysfunctions food and grapefruit juice consumption may significantly affect efficacy and safety of the therapy. All information on the topic is likely to enhance the quality of pharmaceutical care. |
| اللغة: | English |
| تدمد: | 2210-7711 2210-7703 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b4369ae7d285191341d5bbacbb262cTest http://europepmc.org/articles/PMC5124029Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....30b4369ae7d285191341d5bbacbb262c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22107711 22107703 |
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