المؤلفون: Alqurashi Abdulmajeed, Ahmad Waqar, Rahman Ziaur, Nawab Javed, Siddiqui Muhammad Faisal, Akbar Ali, Alkraiem Ayman Ahmad, Latif Muhammad

المصدر: Open Chemistry, Vol 22, Iss 1, Pp 521-30 (2024)

مصطلحات موضوعية: metabolic pathway prediction, periodontal disease, hypothetical proteins, drug target identification, porphyromonas gingivalis, dental disease, drug resistance, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2391-5420Test

الوصول الحر: https://doaj.org/article/499cc69cfdac4a31af3d13394d5473bdTest

المؤلفون: Muhammad Fayaz Khan, Amjad Ali, Hafiz Muzzammel Rehman, Sadiq Noor Khan, Hafiz Muhammad Hammad, Maaz Waseem, Yurong Wu, Taane G. Clark, Abdul Jabbar

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)

مصطلحات موضوعية: Drug target identification, Molecular docking and MD simulation, Drug discovery, Medicine, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2045-2322Test

الوصول الحر: https://doaj.org/article/40ba6f88b61a421d95e5f190f15addaeTest

المؤلفون: Summers, Robert, Pasaje, Charisse, Pisco, Joao, Striepen, Josefine, Luth, Madeline, Kumpornsin, Krittikorn, Carpenter, Emma, Munro, Justin, Lin, De, Plater, Andrew, Punekar, Avinash, Shepherd, Andrew, Shepherd, Sharon, Vanaerschot, Manu, Murithi, James, Rubiano, Kelly, Akidil, Aslı, Ottilie, Sabine, Mittal, Nimisha, Dilmore, A, Won, Madalyn, Mandt, Rebecca, McGowen, Kerry, Owen, Edward, Walpole, Chris, Llinás, Manuel, Lee, Marcus, Fidock, David, Gilbert, Ian, Wirth, Dyann, Niles, Jacquin, Baragaña, Beatriz, Lukens, Amanda, Winzeler, Elizabeth

المصدر: Cell Chemical Biology. 29(2)

مصطلحات موضوعية: Plasmodium falciparum, acetyl-CoA synthetase, antimalarial, drug development, drug target identification, histone acetylation, malaria, mechanism of action, Acetate-CoA Ligase, Antimalarials, Enzyme Inhibitors, Humans, Malaria, Models, Molecular, Molecular Structure, Parasitic Sensitivity Tests, Plasmodium falciparum

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2t51p0mxTest

المؤلفون: Samantha A.W. Crouch, Jan Krause, Thomas Dandekar, Tim Breitenbach

المصدر: Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1755-1772 (2024)

مصطلحات موضوعية: Data-driven modeling, Best parameter fit, Optimal control, Systematic drug target identification, Most effective network influence, External stimuli, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2001037024000941Test; https://doaj.org/toc/2001-0370Test

الوصول الحر: https://doaj.org/article/d3a52f8dfa6047e2b8a697f109ed8816Test

المؤلفون: Kajal Gupta

المصدر: Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-8 (2023)

مصطلحات موضوعية: Monkeypox, Monkeypox virus, Hypothetical proteins, Bioinformatics analysis, Drug target identification, Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2090-5920Test

الوصول الحر: https://doaj.org/article/ca9bbaba34cf4c9ebcbb3bdea58590e0Test

المؤلفون: Aziz Belkadi, Gaurav Thareja, Fatemeh Abbaszadeh, Ramin Badii, Eric Fauman, Omar M.E. Albagha, Karsten Suhre

المصدر: Cell Genomics, Vol 3, Iss 1, Pp 100218- (2023)

مصطلحات موضوعية: human gene knockouts, metabolomics, proteomics, whole-genome sequencing, consanguineous population, drug target validation, drug target identification, Genetics, QH426-470, Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2666979X22001719Test; https://doaj.org/toc/2666-979XTest

الوصول الحر: https://doaj.org/article/e1770f153d584d008d88b05b5bb7250bTest

المؤلفون: Muhammad Shahab, Haitham Al-Madhagi, Guojun Zheng, Amir Zeb, Abdullah Fayez Alasmari, Metab Alharbi, Fawaz Alasmari, Majid Khan, Momin Khan, Abdul Wadood

مصطلحات موضوعية: Role of Histone Deacetylases in Cellular Regulation, Molecular Biology, Biochemistry, Genetics and Molecular Biology, Life Sciences, Computational Methods in Drug Discovery, Computational Theory and Mathematics, Computer Science, Physical Sciences, Role of Carbonic Anhydrases in Medicine and Biotechnology, Drug Target Identification, Oxymorphone, Pharmacology, Medicine, Virtual screening, Docking animal, Cancer research, Chemistry, Internal medicine, Drug discovery, Biochemistry, Oxycodone, Receptor, Opioid, Nursing, FOS Health sciences

العلاقة: https://dx.doi.org/10.60692/6bksg-er207Test

الإتاحة: https://doi.org/10.60692/ycq9z-30h4310.60692/6bksg-er207Test

المؤلفون: Denekew Tenaw Anley, Temesgen Yihunie Akalu, Anteneh Mengist Dessie, Rahel Mulatie Anteneh, Melkamu Aderajew Zemene, Wubet Alebachew Bayih, Yenealem Solomon, Natnael Atnafu Gebeyehu, Gizachew Ambaw Kassie, Misganaw Asmamaw Mengstie, Endeshaw Chekol Abebe, Mohammed Abdu Seid, Molalegn Mesele Gesese, Natnael Moges, Berihun Bantie, Sefineh Fenta Feleke, Tabarak Malik, Getachew Asmare Adella, Achenef Asmamaw Muche

مصطلحات موضوعية: Tuberculosis, Infectious Diseases, FOS Health sciences, Medicine, Health Sciences, Adverse Drug Reactions and Pharmacovigilance, Toxicology, Pharmacology, Toxicology and Pharmaceutics, Life Sciences, Computational Methods in Drug Discovery, Computational Theory and Mathematics, Computer Science, Physical Sciences, Drug Target Identification, Logistic regression, Course navigation, Compliance psychology, Algorithm, Machine learning, Computer science, Artificial intelligence, Multiple drug resistance, Psychology, FOS Psychology, Drug resistance, Pathology, Engineering, Biology, Microbiology, FOS Biological sciences

العلاقة: https://dx.doi.org/10.60692/6v1w8-vta66Test

الإتاحة: https://doi.org/10.60692/6vrf6-6wv9410.60692/6v1w8-vta66Test

المؤلفون: Kjær, Christina, Palasca, Oana, Barzaghi, Guido, Bak, Lasse K., Durhuus, Rúna K.J., Jakobsen, Emil, Pedersen, Louise, Bartels, Emil D., Woldbye, David P.D., Pinborg, Lars H., Jensen, Lars Juhl

المصدر: Kjær , C , Palasca , O , Barzaghi , G , Bak , L K , Durhuus , R K J , Jakobsen , E , Pedersen , L , Bartels , E D , Woldbye , D P D , Pinborg , L H & Jensen , L J 2023 , ' Differential Expression of the β3 Subunit of Voltage-Gated Ca 2+ Channel in Mesial Temporal Lobe Epilepsy ' , Molecular Neurobiology , vol. 60 , pp. 5755–5769 . https://doi.org/10.1007/s12035-023-03426-4Test

مصطلحات موضوعية: CACNB3, Mesial temporal lobe epilepsy, mTLE, Target validation, Transcriptome analysis, Unbiased drug target identification

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1007/s12035-023-03426-4Test
https://curis.ku.dk/portal/da/publications/differential-expression-of-the-3-subunit-of-voltagegated-ca2-channel-in-mesial-temporal-lobe-epilepsyTest(6a906ce9-fb80-461e-8420-ae2dcaed13da).html
https://curis.ku.dk/ws/files/367836758/s12035_023_03426_4.pdfTest

المؤلفون: Chris J. Radoux, Francesca Vianello, Jake McGreig, Nikita Desai, Anthony R. Bradley

المصدر: Frontiers in Bioinformatics, Vol 2 (2022)

مصطلحات موضوعية: druggability, druggable genome, tractability, knowledge graph, drug target identification, artificial intelligence, Computer applications to medicine. Medical informatics, R858-859.7

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fbinf.2022.958378/fullTest; https://doaj.org/toc/2673-7647Test

الوصول الحر: https://doaj.org/article/d95b91af827e40beba23f2ba7203ac19Test