المؤلفون: Dregni, Aurelio J.

مرشدي الرسالة: Hong, Mei, Massachusetts Institute of Technology. Department of Chemistry

وصف الملف: application/pdf

الإتاحة: https://hdl.handle.net/1721.1/145173Test
https://orcid.org/0000-0003-3422-4734Test

المؤلفون: Somberg, Noah H, Wu, Westley W, Medeiros-Silva, João, Dregni, Aurelio J, Jo, Hyunil, DeGrado, William F, Hong, Mei

المصدر: Biochemistry. 61(21)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Prevention, Rare Diseases, Infectious Diseases, Emerging Infectious Diseases, Lung, Lipid Bilayers, Protein Domains, SARS-CoV-2, Viroporin Proteins, Coronavirus Envelope Proteins, Medicinal and Biomolecular Chemistry, Medical Biochemistry and Metabolomics, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medical biochemistry and metabolomics, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1q2146qsTest

المؤلفون: Dregni, Aurelio J, Mandala, Venkata S, Wu, Haifan, Elkins, Matthew R, Wang, Harrison K, Hung, Ivan, DeGrado, William F, Hong, Mei

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(33)

مصطلحات موضوعية: Dementia, Rare Diseases, Neurosciences, Neurodegenerative, Acquired Cognitive Impairment, Aging, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease, Alzheimer Disease, Amino Acid Sequence, Cryoelectron Microscopy, Cytoskeleton, Humans, Microtubule-Associated Proteins, Microtubules, Nuclear Magnetic Resonance, Biomolecular, Protein Aggregation, Pathological, Protein Binding, Protein Conformation, beta-Strand, Protein Domains, Protein Structure, Secondary, tau Proteins, solid-state NMR, conformational polymorphism, polymorphism

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/37h857fgTest

المؤلفون: Dregni, Aurelio J., McKay, Matthew, Surya, Wahyu, Queralt-Martin, Maria, Medeiros-Silva, João, Wang, Harrison K., Aguilella, Vicente, Torres, Jaume, Hong, Mei

مصطلحات موضوعية: solid-state NMR, structure determination, membrane curvature, viroporin, oligomerization

وصف الملف: application/pdf

العلاقة: Journal of Molecular Biology 435 (2023) 167966; https://ars.els-cdn.com/content/image/1-s2.0-S0022283623000220-mmc1.pdfTest // https://ars.els-cdn.com/content/image/1-s2.0-S0022283623000220-mmc2.xlsxTest; Aurelio J. Dregni, Matthew J. McKay, Wahyu Surya, Maria Queralt-Martin, João Medeiros-Silva, Harrison K. Wang, Vicente Aguilella, Jaume Torres, Mei Hong, The Cytoplasmic Domain of the SARS-CoV-2 Envelope Protein Assembles into a β-Sheet Bundle in Lipid Bilayers, Journal of Molecular Biology, Volume 435, Issue 5, 2023, 167966, ISSN 0022-2836, https://doi.org/10.1016Test/j.jmb.2023.167966.; http://hdl.handle.net/10234/204131Test; https://doi.org/10.1016Test/j.jmb.2023.167966

الإتاحة: https://doi.org/10.1016Test/j.jmb.2023.167966
http://hdl.handle.net/10234/204131Test

المؤلفون: Medeiros-Silva, João, Dregni, Aurelio J., Somberg, Noah H., Duan, Pu, Hong, Mei

المصدر: American Association for the Advancement of Science

مصطلحات موضوعية: Multidisciplinary

وصف الملف: application/pdf

العلاقة: https://hdl.handle.net/1721.1/153521Test; João Medeiros-Silva et al. ,Atomic structure of the open SARS-CoV-2 E viroporin.Sci. Adv.9,eadi9007(2023).

الإتاحة: https://hdl.handle.net/1721.1/153521Test

المؤلفون: El Mammen, Nadia¹, Dregni, Aurelio J.¹, Pu Duan¹, Mei Hong¹ meihong@mit.edu

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 3/5/2024, Vol. 121 Issue 10, p1-10. 44p.

مصطلحات موضوعية: *NEUROFIBRILLARY tangles, *POST-translational modification, *TAU proteins, *AMYLOID beta-protein, *ALZHEIMER'S disease, *TAUOPATHIES, *MICROTUBULE-associated proteins, *ATOMIC structure

المؤلفون: Dregni, Aurelio J., Wang, Harrison K., Wu, Haifan, Duan, Pu, Jin, Jia, DeGrado, William F., Hong, Mei

المصدر: PMC

وصف الملف: application/octet-stream

العلاقة: http://dx.doi.org/10.1021/jacs.1c03314Test; Journal of the American Chemical Society; https://hdl.handle.net/1721.1/141076.2Test; Dregni, Aurelio J, Wang, Harrison K, Wu, Haifan, Duan, Pu, Jin, Jia et al. 2021. "Inclusion of the C-Terminal Domain in the β-Sheet Core of Heparin-Fibrillized Three-Repeat Tau Protein Revealed by Solid-State Nuclear Magnetic Resonance Spectroscopy." Journal of the American Chemical Society, 143 (20).

الإتاحة: https://doi.org/10.1021/jacs.1c03314Test
https://hdl.handle.net/1721.1/141076.2Test

المؤلفون: Gelenter, Martin D, Dregni, Aurelio J, Duan, Pu, Hong, Mei

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: PMC

وصف الملف: application/pdf

العلاقة: Biochemistry; https://hdl.handle.net/1721.1/141078Test; Gelenter, Martin D, Dregni, Aurelio J, Duan, Pu and Hong, Mei. 2021. "Structurally Based Design of Glucagon Mutants That Inhibit Fibril Formation." Biochemistry, 60 (25).

الإتاحة: https://hdl.handle.net/1721.1/141078Test

المؤلفون: Duan, Pu, Chen, Kelly J, Wijegunawardena, Gayani, Dregni, Aurelio J, Wang, Harrison K, Wu, Haifan, Hong, Mei

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: PMC

وصف الملف: application/pdf

العلاقة: Journal of the American Chemical Society; https://hdl.handle.net/1721.1/141080Test; Duan, Pu, Chen, Kelly J, Wijegunawardena, Gayani, Dregni, Aurelio J, Wang, Harrison K et al. 2022. "Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer’s β-Amyloid Fibrils Studied Using 19F Solid-State NMR." Journal of the American Chemical Society, 144 (3).

الإتاحة: https://hdl.handle.net/1721.1/141080Test

المؤلفون: Shcherbakov, Alexander A, Spreacker, Peyton J, Dregni, Aurelio J, Henzler-Wildman, Katherine A, Hong, Mei

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: Nature

وصف الملف: application/pdf

العلاقة: Nature Communications; https://hdl.handle.net/1721.1/141081Test; Shcherbakov, Alexander A, Spreacker, Peyton J, Dregni, Aurelio J, Henzler-Wildman, Katherine A and Hong, Mei. 2022. "High-pH structure of EmrE reveals the mechanism of proton-coupled substrate transport." Nature Communications, 13 (1).

الإتاحة: https://hdl.handle.net/1721.1/141081Test