التفاصيل البيبلوغرافية
| العنوان: |
Quality of Life in the First Year after Ischemic Stroke Treated with Acute Revascularization Therapy. |
| المؤلفون: |
Do Rego, Aboudou Matinou1,2 (AUTHOR) gauthier.duloquin@chu-dijon.fr, Duloquin, Gauthier2,3 (AUTHOR) marie.sauvant@chu-dijon.fr, Sauvant, Marie2,3 (AUTHOR) simon.amaral@chu-dijon.fr, Amaral, Simon2,3 (AUTHOR) quentin.thomas@chu-dijon.fr, Thomas, Quentin2,3 (AUTHOR), Devilliers, Hervé1,4 (AUTHOR) herve.devilliers@chu-dijon.fr, Béjot, Yannick2,3 (AUTHOR) yannick.bejot@chu-dijon.fr |
| المصدر: |
Journal of Clinical Medicine. Jun2022, Vol. 11 Issue 11, p3240-3240. 16p. |
| مصطلحات موضوعية: |
*ISCHEMIC stroke, *QUALITY of life, *STROKE patients, *SOCIAL role |
| مستخلص: |
(1) Background: we aimed to describe the disease-specific quality of life (QoL) of ischemic stroke patients treated with acute revascularization therapy, its evolution from 6 months to 12 months, and associated factors. (2) Methods: QoL was assessed with the SS-QoL in consecutive patients treated with either intravenous thrombolysis (IVT) and/or mechanical thrombectomy (MT). Variables associated with QoL scores and its evolution were studied using multivariate mixed models, and interaction with time. Analyses were performed in four domains of SS-QoL: self-care, mobility, mood, and social roles. (3) Results: Among the 501 included patients (mean (sd) age 68.9 (14.5), 49% women), lower post-stroke QoL was independently related to lower level of school education, prestroke mRS > 2, and 24 h NIHSS score > 4. Independent predictors of unfavorable evolution of QoL over time were age <75 years (Mobility p = 0.0194 and Mood p = 0.0015), NIHSS score ≤ 4, (Self-care p = 0.0053 and Mood p = 0.0048), and modified Rankin Scale score ≤ 2 (Social roles, p = 0.0006). Revascularization therapy had no significant effect on the QoL scores, but patients treated with MT (alone or as bridging therapy) had significantly greater improvement in mobility score between 6 and 12 months than patients treated with IVT alone (p = 0.0072). (4) Conclusion: QoL evolution over one year had only slight variation and was associated with the modalities of acute treatment, age, and stroke severity. [ABSTRACT FROM AUTHOR] |
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