المؤلفون: Li, Z, Wang, C, Wang, Z, Zhu, C, Li, J, Sha, T, Ma, L, Gao, C, Yang, Y, Sun, Y, Wang, J, Sun, X, Lu, C, Difiglia, M, Mei, Y, Ding, C, Luo, S, Dang, Y, Ding, Y, Fei, Y, Lu, B

وصف الملف: 203 - 209

العلاقة: E-ISSN:1476-4687; http://hdl.handle.net/10026.1/15145Test

الإتاحة: https://doi.org/10.1038/s41586-019-1722-1Test
http://hdl.handle.net/10026.1/15145Test

المؤلفون: Quinti, L, Naidu, SD, Trager, U, Chen, X, Kegel-Gleason, K, Lleres, D, Connolly, C, Chopra, V, Low, C, Moniot, S, Sapp, E, Tousley, AR, Vodicka, P, Van Kanegan, MJ, Kaltenbach, LS, Crawford, LA, Fuszard, M, Higgins, M, Miller, JRC, Farmer, RE, Potluri, V, Samajdar, S, Meisel, L, Zhang, N, Snyder, A, Stein, R, Hersch, SM, Ellerby, LM, Weerapana, E, Schwarzschild, MA, Steegborn, C, Leavitt, BR, Degterev, A, Tabrizi, SJ, Lo, DC, DiFiglia, M, Thompson, LM, Dinkova-Kostova, AT, Kazantsev, AG

المصدر: PNAS - Proceedings of the National Academy of Sciences of the United States of America , 114 (23) E4676-E4685. (2017)

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, Huntington's disease, KEAP1/NRF2/ARE signaling, NRF2 inducer, antiinflammatory responses, human neural stem cells, TRANSCRIPTION FACTOR NRF2, CUL3-BASED E3 LIGASE, FUMARIC-ACID ESTERS, OXIDATIVE STRESS, PARKINSONS-DISEASE, NEURODEGENERATIVE DISEASES, MOUSE MODEL, PROTEASOMAL DEGRADATION, MICROGLIAL ACTIVATION, KEAP1-NRF2 SYSTEM

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/1554738/1/PNAS_final.pdfTest; https://discovery.ucl.ac.uk/id/eprint/1554738Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/1554738/1/PNAS_final.pdfTest
https://discovery.ucl.ac.uk/id/eprint/1554738Test/

المؤلفون: DiFiglia, M., Sena-Esteves, M., Chase, K., Sapp, E., Pfister, E., Sass, M., Yoder, J., Reeves, P., Pandey, R. K., Rajeev, K. G., Manoharan, M., Sah, D. W. Y., Zamore, P. D., Aronin, N.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2007 Oct . 104(43), 17204-17209.

الوصول الحر: https://www.jstor.org/stable/25450206Test

المؤلفون: Graveland, G. A., Williams, R. S., DiFiglia, M.

المصدر: Science, 1985 Feb . 227(4688), 770-773.

الوصول الحر: https://www.jstor.org/stable/1695140Test

المؤلفون: O'Rourke, J.G., Gareau, J.R., Ochaba, J., Song, W., Raskó, T., Reverter, D., Lee, J., Monteys, A.M., Pallos, J., Mee, L., Vashishtha, M., Apostol, B.L., Nicholson, T.P., Illes, K., Zhu, Y.Z., Dasso, M., Bates, G.P., Difiglia, M., Davidson, B., Wanker, E.E., Marsh, J.L., Lima, C.D., Steffan, J.S., Thompson, L.M.

مصطلحات موضوعية: Function and Dysfunction of the Nervous System

وصف الملف: application/pdf

العلاقة: http://edoc.mdc-berlin.de/13184/1/13184oa.pdfTest; SUMO-2 and PIAS1 modulate insoluble mutant Huntingtin protein accumulation. O'Rourke, J.G. and Gareau, J.R. and Ochaba, J. and Song, W. and Raskó, T. and Reverter, D. and Lee, J. and Monteys, A.M. and Pallos, J. and Mee, L. and Vashishtha, M. and Apostol, B.L. and Nicholson, T.P. and Illes, K. and Zhu, Y.Z. and Dasso, M. and Bates, G.P. and Difiglia, M. and Davidson, B. and Wanker, E.E. and Marsh, J.L. and Lima, C.D. and Steffan, J.S. and Thompson, L.M. Cell Reports 4 (2): 362-375. 25 July 2013

الإتاحة: https://doi.org/10.1016/j.celrep.2013.06.034Test
http://edoc.mdc-berlin.de/13184Test/
https://edoc.mdc-berlin.de/13184Test/
http://edoc.mdc-berlin.de/13184/1/13184oa.pdfTest

المؤلفون: Fox, JH, Connor, T, Chopra, V, Dorsey, K, Kama, JA, Bleckmann, D, Betschart, C, Hoyer, D, Frentzel, S, DiFiglia, M, Paganetti, P, Hersch, SM

العلاقة: pii: 1750-1326-5-26; Fox, J. H., Connor, T., Chopra, V., Dorsey, K., Kama, J. A., Bleckmann, D., Betschart, C., Hoyer, D., Frentzel, S., DiFiglia, M., Paganetti, P. & Hersch, S. M. (2010). The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease. MOLECULAR NEURODEGENERATION, 5 (1), https://doi.org/10.1186/1750-1326-5-26Test.; http://hdl.handle.net/11343/264755Test

الإتاحة: https://doi.org/10.1186/1750-1326-5-26Test
http://hdl.handle.net/11343/264755Test

المؤلفون: Hruska-Plochán, M, Juhas, S, Juhasova, J, Galik, J, Miyanohara, A, Marsala, M, Bjarkam, C R, Cattaneo, E, DiFiglia, M, Li, X-J, Motlik, J

مصطلحات موضوعية: EHDN Plenary Meeting: abstracts

وصف الملف: text/html

العلاقة: http://jnnp.bmj.com/cgi/content/short/81/Suppl_1/A9Test; http://dx.doi.org/10.1136/jnnp.2010.222570.27Test

الإتاحة: https://doi.org/10.1136/jnnp.2010.222570.27Test
http://jnnp.bmj.com/cgi/content/short/81/Suppl_1/A9Test

المؤلفون: Baxa, M, Juhas, S, Pavlok, A, Vodicka, P, Juhasova, J, Hruska-Plochán, M, Miyanohara, A, Marsala, M, Cattaneo, E, Difiglia, M, Motlik, J

مصطلحات موضوعية: EHDN Plenary Meeting: abstracts

وصف الملف: text/html

العلاقة: http://jnnp.bmj.com/cgi/content/short/81/Suppl_1/A8-bTest; http://dx.doi.org/10.1136/jnnp.2010.222570.26Test

الإتاحة: https://doi.org/10.1136/jnnp.2010.222570.26Test
http://jnnp.bmj.com/cgi/content/short/81/Suppl_1/A8-bTest

المؤلفون: Sapp, E., Kegel, K. B., Aronin, N., Hashikawa, T., Uchiyama, Y., Tohyama, K., Bhide, P. G., Vonsattel, J. P., Difiglia, M.

المصدر: Journal of Neuropathology & Experimental Neurology ; volume 60, issue 2, page 161-172 ; ISSN 0022-3069 1554-6578

الإتاحة: https://doi.org/10.1093/jnen/60.2.161Test
http://academic.oup.com/jnen/article-pdf/60/2/161/8133511/60-2-161.pdfTest

المؤلفون: Mačáková, M. (Monika), Bohuslavová, B. (Božena), Vochozková, P. (Petra), Pavlok, A. (Antonín), Sedláčková, M., Vidinská, D. (Daniela), Vochyánová, K. (Klára), Lišková, I. (Irena), Valeková, I. (Ivona), Baxa, M. (Monika), Ellederová, Z. (Zdeňka), Klíma, J. (Jiří), Juhás, Š. (Štefan), Juhásová, J. (Jana), Kloučková, J., Haluzík, M., Klempíř, J., Hansíková, H., Spáčilová, J., Collins, R., Blumenthal, I., Talkowski, M., Gusella, J. F., Howland, D. S., DiFiglia, M., Motlík, J. (Jan)

مصطلحات موضوعية: Huntington´s disease, pig model, mutant huntingtin

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26959244; urn:pissn: 1660-2854; urn:eissn: 1660-2862; http://hdl.handle.net/11104/0260091Test

الإتاحة: https://doi.org/10.1159/000443665Test
http://hdl.handle.net/11104/0260091Test