Clinical and dermoscopic features of Fibroepithelioma of Pinkus: case series with an emphasis on hypopigmented to pink lines intersecting at acute angles
| العنوان: | Clinical and dermoscopic features of Fibroepithelioma of Pinkus: case series with an emphasis on hypopigmented to pink lines intersecting at acute angles |
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| المؤلفون: | Katherine R Lee, Michelle Levy, Diana M Forero Cuevas, Nadeem G. Marghoob, Ashfaq A. Marghoob, Klaus J. Busam, Ofer Reiter, Japbani K Nanda |
| المصدر: | Arch Dermatol Res |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Skin Neoplasms, Fibroepithelioma, Biopsy, Dermoscopy, Skin Pigmentation, Dermatology, Article, Diagnosis, Differential, Lesion, Young Adult, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Nevus, Basal cell carcinoma, Aged, Retrospective Studies, Skin, Aged, 80 and over, medicine.diagnostic_test, business.industry, Erythematous papule, Mean age, General Medicine, Middle Aged, medicine.disease, Carcinoma, Basal Cell, 030220 oncology & carcinogenesis, Female, Histopathology, medicine.symptom, business |
| الوصف: | Fibroepithelioma of Pinkus (FEP) is a subtype of basal cell carcinoma (BCC) that can clinically resemble intradermal nevi (IDN) and fibromas. We performed a retrospective review of consecutively biopsied lesions confirmed to be FEP on histopathology diagnosed from January 1, 2008 to April 8, 2019. Clinical (n = 48), contact non-polarized dermoscopy (NPD) (n = 44), and contact polarized dermoscopy (PD) (n = 22) images from 36 patients were reviewed. Mean age was 64.5 years (SD 15.1 years, range 24-86 years) at diagnosis of first FEP lesion. Most lesions were located on the torso (n = 28, 58.3%), followed by the lower extremity (n = 9, 18.8%). The most common differential diagnoses at the time of biopsy included BCC (n = 40) and nevus (other than IDN, n = 5). Clinically, FEP were pink (95.8%), scaly (66.7%) papules (77.1%) displaying disrupted skin markings (62.5%) and absence of hair follicles (87.5%). NPD revealed serpentine (97.7%), dotted (81.8%), or polymorphous vessels (86.4%), and hypopigmented to pink lines intersecting at acute angles (HPLA) (52.3%). PD demonstrated serpentine (95.5%), dotted (86.4%), or polymorphous vessels (81.8%), shiny white lines (50.0%), and HPLA (59.1%). Classic features of BCC such as arborizing vessels (n = 2), ulceration (n = 1), shiny white blotches and strands (n = 1), blue-gray ovoid nest (n = 1), and leaf-like areas (n = 1) were uncommon. FEP often presents as scaly, erythematous papules with disrupted skin markings and absence of hair follicles. Dermoscopy reveals polymorphous vessels with shiny white lines and HPLA. |
| تدمد: | 1432-069X 0340-3696 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0137f1d986439a628fb40ff51a2f1c44Test https://doi.org/10.1007/s00403-020-02142-6Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0137f1d986439a628fb40ff51a2f1c44 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1432069X 03403696 |
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