المؤلفون: Dance, Arnaud, Fernandes, Justine, Toussaint, Bénédicte, Vaillant, Emmanuel, Boutry, Raphaël, Baron, Morgane, Loiselle, Hélène, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Ibberson, Mark, Marre, Michel, GERNAY, Marie-Marie, Fadeur, Marjorie, Paquot, Nicolas, Vaxillaire, Martine, Boissel, Mathilde, Amanzougarene, Souhila, Derhourhi, Mehdi, Khamis, Amna, Froguel, Philippe, Bonnefond, Amélie

المصدر: Molecular Metabolism, 79, 101867 (2024-01)

مصطلحات موضوعية: Insulin, Glucose, P2RY1 protein, human, Receptors, Purinergic P2Y1, Humans, Insulin/metabolism, Genomics, Glucose/metabolism, Receptors, Purinergic P2Y1/genetics, Receptors, Purinergic P2Y1/metabolism, Diabetes Mellitus, Type 2/genetics, Diabetes Mellitus, Type 2/metabolism, Islets of Langerhans/metabolism, Diabetes Mellitus, Type 2, Islets of Langerhans, Molecular Biology, Cell Biology, Human health sciences, Endocrinology, metabolism & nutrition, Sciences de la santé humaine, Endocrinologie, métabolisme & nutrition

العلاقة: https://api.elsevier.com/content/article/PII:S2212877823002016?httpAccept=text/xmlTest; urn:issn:2212-8778

الوصول الحر: https://orbi.uliege.be/handle/2268/318415Test

المؤلفون: Veitch, Shawn, Njock, Makon-Sébastien, Chandy, Mark, Siraj, M Ahsan, Chi, Lijun, Mak, HaoQi, Yu, Kai, Rathnakumar, Kumaragurubaran, Perez-Romero, Carmina Anjelica, Chen, Zhiqi, Alibhai, Faisal J, Gustafson, Dakota, Raju, Sneha, Wu, Ruilin, Zarrin Khat, Dorrin, Wang, Yaxu, Caballero, Amalia, Meagher, Patrick, Lau, Edward, Pepic, Lejla, Cheng, Henry S, Galant, Natalie J, Howe, Kathryn L, Li, Ren-Ke, Connelly, Kim A, Husain, Mansoor, Delgado-Olguin, Paul, Fish, Jason E

المصدر: Cardiovascular Diabetology, 21 (1), 31 (2022-02)

مصطلحات موضوعية: Biomarker, Diabetes, Diastolic dysfunction, Endothelial cell, Extracellular vesicle, Heart failure with preserved ejection fraction, Microvasculature, microRNA, Biomarkers, Fatty Acids, MIRN30 microRNA, rat, MicroRNAs, Mirn30d microRNA, mouse, Animals, Endothelial Cells/metabolism, Endothelial Cells/pathology, Fatty Acids/metabolism, Mice, Rats, Stroke Volume, Diabetes Mellitus, Type 2/diagnosis, Diabetes Mellitus, Type 2/genetics, Heart Failure, MicroRNAs/genetics, MicroRNAs/metabolism, Diabetes Mellitus, Type 2, Endothelial Cells, Internal Medicine, Endocrinology, Diabetes and Metabolism, Cardiology and Cardiovascular Medicine, Human health sciences, Cardiovascular & respiratory systems, Sciences de la santé humaine, Systèmes cardiovasculaire & respiratoire

العلاقة: https://link.springer.com/content/pdf/10.1186/s12933-022-01458-z.pdfTest; urn:issn:1475-2840

الوصول الحر: https://orbi.uliege.be/handle/2268/288909Test

المؤلفون: Sinéad M McGlacken-Byrne, Jasmina Kallefullah Mohammad, Niamh Conlon, Diliara Gubaeva, Julie Siersbæk, Anders Jørgen Schou, Huseyin Demirbilek, Antonia Dastamani, Jayne A L Houghton, Klaus Brusgaard, Maria Melikyan, Henrik Christesen, Sarah E Flanagan, Nuala P Murphy, Pratik Shah

المصدر: McGlacken-Byrne, S M, Mohammad, J K, Conlon, N, Gubaeva, D, Siersbæk, J, Schou, A J, Demirbilek, H, Dastamani, A, Houghton, J A L, Brusgaard, K, Melikyan, M, Christesen, H, Flanagan, S E, Murphy, N P & Shah, P 2022, ' Clinical and genetic heterogeneity of HNF4A/HNF1A mutations in a multicentre paediatric cohort with hyperinsulinaemic hypoglycaemia ', European Journal of Endocrinology, vol. 186, no. 4, pp. 417-427 . https://doi.org/10.1530/EJE-21-0897Test

مصطلحات موضوعية: Male, Adolescent, Endocrinology, Diabetes and Metabolism, Cohort Studies, Genetic Heterogeneity, Endocrinology, Hyperinsulinism, Diabetes Mellitus, Type 1/genetics, Birth Weight, Humans, Hepatocyte Nuclear Factor 1-alpha, Hepatocyte Nuclear Factor 1-alpha/genetics, Child, Medical History Taking, Diazoxide/therapeutic use, Hyperinsulinism/drug therapy, Diazoxide, Infant, Newborn, Infant, General Medicine, Fanconi Syndrome, Hypoglycemia, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hepatocyte Nuclear Factor 4, Hepatocyte Nuclear Factor 4/genetics, Child, Preschool, Mutation, Diabetes Mellitus, Type 2/genetics, Hypoglycemia/drug therapy, Female, Fanconi Syndrome/genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c633e75590c4bd7905fb8beb09f440Test
https://doi.org/10.1530/eje-21-0897Test

المؤلفون: Arjen J, Cupido, Folkert W, Asselbergs, Pradeep, Natarajan, Paul M, Ridker, G Kees, Hovingh, A Floriaan, Schmidt

المساهمون: Graduate School, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, ACS - Amsterdam Cardiovascular Sciences, Cardiology, ACS - Heart failure & arrhythmias, Experimental Vascular Medicine

المصدر: British journal of clinical pharmacology, 88(6), 2875-2884. Wiley-Blackwell

مصطلحات موضوعية: Type 2/genetics, Coronary Artery Disease, Polymorphism, Single Nucleotide, Rheumatoid/drug therapy, Arthritis, Rheumatoid, Receptors, Interleukin-6/genetics, Risk Factors, Atrial Fibrillation, Receptors, Diabetes Mellitus, Humans, Pharmacology (medical), Polymorphism, Interleukin-6/genetics, Ischemic Stroke, Pharmacology, Interleukin-6, Arthritis, Coronary Artery Disease/genetics, Single Nucleotide, Mendelian Randomization Analysis, Receptors, Interleukin-6, Diabetes Mellitus, Type 2, Arthritis, Rheumatoid/drug therapy, Diabetes Mellitus, Type 2/genetics, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03b23fdb8de2356f5ab0110768175e9Test
https://doi.org/10.1111/bcp.15191Test

المؤلفون: Dørflinger, G. H., Høyem, P. H., Laugesen, E., Østergaard, J. A., Funck, K. L., Steffensen, R., Poulsen, P. L., Hansen, T. K., Bjerre, M.

المصدر: Dørflinger, G H, Høyem, P H, Laugesen, E, Østergaard, J A, Funck, K L, Steffensen, R, Poulsen, P L, Hansen, T K & Bjerre, M 2022, ' High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes ', Frontiers in Immunology, vol. 13, 1080388 . https://doi.org/10.3389/fimmu.2022.1080388Test

مصطلحات موضوعية: Genotype, Kidney/physiology, Immunology, diabetes duration, albuminuria, MBL genotypes, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Mannose-Binding Lectin/genetics, mannan-binding lectin, Diabetes Mellitus, Type 2/genetics, Humans, Immunology and Allergy, T2D, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131c96112edc3fe6898ade5d8c1c789fTest
https://pubmed.ncbi.nlm.nih.gov/36618347Test

المؤلفون: Carsten Friis Rundsten, Torben Hansen, Ivan Brandslund, Marta Guindo-Martínez, Mitja I. Kurki, Jose C. Florez, Sílvia Bonàs-Guarch, Aaron Leong, Joanne B. Cole, Kumar Veerapen, Niels Grarup, Josep M. Mercader, Mark J. O'Connor, Allan Linneberg, Varinderpal Kaur, David Torrents, Philip Schroeder, Paula Cortes-Sánchez, Oluf Pedersen, Alicia Huerta-Chagoya

المصدر: O'Connor, M J, Schroeder, P, Huerta-Chagoya, A, Cortés-Sánchez, P, Bonàs-Guarch, S, Guindo-Martínez, M, Cole, J B, Kaur, V, Torrents, D, Veerapen, K, Grarup, N, Kurki, M, Rundsten, C F, Pedersen, O, Brandslund, I, Linneberg, A, Hansen, T, Leong, A, Florez, J C & Mercader, J M 2022, ' Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes ', Diabetes, vol. 71, no. 3, pp. 554-565 . https://doi.org/10.2337/db21-0545Test
Diabetes

مصطلحات موضوعية: Adult, Male, Endocrinology, Diabetes and Metabolism, Genes, Recessive, Genome-wide association study, Type 2 diabetes, Biology, Europe/ethnology, Sex Factors, Gene Frequency, Genes, Recessive/genetics, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, Allele, Gene, Triglycerides, Genetic association, Genetics, Genetic Predisposition to Disease/genetics, Homozygote, Metabolome/genetics, Genetics/Genomes/Proteomics/Metabolomics, Cholesterol, LDL, Odds ratio, Middle Aged, medicine.disease, Genetic architecture, Europe, Minor allele frequency, Triglycerides/blood, Diabetes Mellitus, Type 2, Cholesterol, LDL/blood, Mutation, Metabolome, Diabetes Mellitus, Type 2/genetics, Female, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db48eb07b0bc907f358504be55446e94Test
https://portal.findresearcher.sdu.dk/da/publications/828dd316-3d73-43bd-ad39-c4d38447ca63Test

المؤلفون: Jean-Gael Diserens, Laure Quignodon, Federica Gilardi, Chiara Sardella, Béatrice Desvergne, Barbara Toffoli, Frédéric Preitner, Carine Winkler, Mariano Schiffrin

المصدر: Metabolism, vol. 95, pp. 8-20

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Peroxisome proliferator-activated receptor gamma, Lipodystrophy, Endocrinology, Diabetes and Metabolism, Lipid Metabolism Disorders, Adipose tissue, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Carbohydrate metabolism, Mice, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Pregnancy, Internal medicine, medicine, Hyperinsulinemia, Animals, Lipoatrophy, Organ Size, medicine.disease, PPAR gamma, Glucose, 030104 developmental biology, Adipose Tissue, Diabetes Mellitus, Type 2, Hypermetabolism, Adipose Tissue/anatomy & histology, Diabetes Mellitus, Type 2/genetics, Diabetes Mellitus, Type 2/metabolism, Energy Metabolism/genetics, Female, Gene Deletion, Glucose/metabolism, Lipid Metabolism Disorders/genetics, Lipid Metabolism Disorders/metabolism, Lipodystrophy/genetics, Lipodystrophy/metabolism, Organ Size/genetics, PPAR gamma/genetics, In-depth metabolic exploration, Metabolic inflexibility, PPARγ, Energy Metabolism

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084179dd7cdce53e67b482b2dd965cbfTest
https://doi.org/10.1016/j.metabol.2019.03.003Test

المؤلفون: Marie Gasser, Sébastien Lenglet, Nasim Bararpour, Tatjana Sajic, Kim Wiskott, Marc Augsburger, Tony Fracasso, Federica Gilardi, Aurélien Thomas

المصدر: Toxicology, vol. 470, pp. 153153

مصطلحات موضوعية: Adipocytes/metabolism, Adipose Tissue/metabolism, Cadmium/toxicity, Diabetes Mellitus, Type 2/genetics, Humans, Insulin/metabolism, Metabolic Diseases, Obesity/chemically induced, Obesity/genetics, Transcriptome, Zinc/metabolism, Adipose tissue concentrations, Cadmium, Cellular homeostasis, Human adipocytes, Metallothioneins, SLC transporters, Zinc, Adipose Tissue, Diabetes Mellitus, Type 2, Adipocytes, Insulin, Obesity, Toxicology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03099801fa0226311ea51175442886f7Test
https://doi.org/10.1016/j.tox.2022.153153Test

المؤلفون: Viji Nair, Jonathan Allington, Jeffrey M P Holly, Ruth Rollason, Bryony Hayes, Holly Stowell-Connolly, Claire M Perks, Jenny A Hurcombe, Lawrence Gillam, Gavin I. Welsh, Lorna J Hale, Craig A. McArdle, Robert J P Pope, Abigail C Lay, Eva Marquez, Richard J M Coward, Robert G. Nelson, Wenjun Ju, Matthias Kretzler, Timothy Roberts

المصدر: Diabetologia
Lay, A C, Hale, L J, Stowell-Connolly, H, Pope, R J P, Nair, V, Ju, W, Marquez, E, Rollason, R, Hurcombe, J A, Hayes, B, Roberts, T, Gillam, L, Allington, J, Nelson, R G, Kretzler, M, Holly, J M P, Perks, C M, McArdle, C A, Welsh, G I & Coward, R J M 2021, ' IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes ', Diabetologia, vol. 64, no. 7, pp. 1690-1702 . https://doi.org/10.1007/s00125-021-05427-1Test

مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Biopsy, Cell, Kidney Glomerulus, FOXO1, Diabetic nephropathy, Fkhr, Kidney, Podocyte, Pathogenesis, Cohort Studies, 0302 clinical medicine, Focal Adhesion Protein-Tyrosine Kinases/metabolism, Diabetic Nephropathies, Cells, Cultured, Integrin beta1/metabolism, Kinase, Podocytes, Integrin beta1, Motility, Cell biology, medicine.anatomical_structure, FoxO1, 030220 oncology & carcinogenesis, Adhesion, Diabetes Mellitus, Type 2/genetics, Signal Transduction, Podocytes/metabolism, Kidney Glomerulus/metabolism, Diabetic Nephropathies/genetics, Biology, Endothelial Cells/metabolism, Article, 03 medical and health sciences, Internal Medicine, medicine, Humans, Viability assay, PI3K/AKT/mTOR pathway, FAK, β1-integrin, Endothelial Cells, IGFBP-1, medicine.disease, Insulin-Like Growth Factor Binding Protein 1, Kidney/metabolism, 030104 developmental biology, Diabetes Mellitus, Type 2, Focal Adhesion Protein-Tyrosine Kinases, Glomerulus, Signal Transduction/genetics, Insulin-Like Growth Factor Binding Protein 1/genetics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4761651956872b5d61bf58fab5c3ce4aTest

المؤلفون: Eliasson, L., Regazzi, R.

المصدر: Journal of molecular biology, vol. 432, no. 5, pp. 1419-1428

مصطلحات موضوعية: Animals, Diabetes Mellitus, Type 2/genetics, Diabetes Mellitus, Type 2/metabolism, Epigenesis, Genetic, Gene Expression, Glucose/metabolism, Humans, Insulin/metabolism, Insulin-Secreting Cells/metabolism, Islets of Langerhans/metabolism, MicroRNAs/genetics, MicroRNAs/metabolism, RNA, Long Noncoding/genetics, Glucotoxicity, Insulin, Lipotoxicity, MicroRNA, β-cell

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______1900::a3af912ba4ee3079fe809026475ee8f2Test
https://serval.unil.ch/notice/serval:BIB_8AAD43279046Test