المؤلفون: Nelson, Louisa, Barnes, Bethany M., Tighe, Anthony, Littler, Samantha, Coulson-Gilmer, Camilla, Golder, Anya, Desai, Sudha, Morgan, Robert D., Mcgrail, Joanne, Taylor, Stephen S.

المصدر: Nelson , L , Barnes , B M , Tighe , A , Littler , S , Coulson-Gilmer , C , Golder , A , Desai , S , Morgan , R D , Mcgrail , J & Taylor , S S 2023 , ' Exploiting a living biobank to delineate mechanisms underlying disease-specific chromosome instability ' , Chromosome Research , vol. 31 , no. 3 , 21 . https://doi.org/10.1007/s10577-023-09731-xTest

مصطلحات موضوعية: Chromosome instability, tumour heterogeneity, cancer genomics, ovarian cancer

العلاقة: https://research.manchester.ac.uk/en/publications/5eca3fcd-4891-4f28-91a3-d2357297a67dTest

الإتاحة: https://doi.org/10.1007/s10577-023-09731-xTest
https://research.manchester.ac.uk/en/publications/5eca3fcd-4891-4f28-91a3-d2357297a67dTest

المؤلفون: Morgan, Robert D, Burghel, George J, Flaum, Nicola, Bulman, Michael, Smith, Philip, Clamp, Andrew R, Hasan, Jurjees, Mitchell, Claire, Salih, Zena, Woodward, Emma R, Lalloo, Fiona, Shaw, Joseph, Desai, Sudha, Crosbie, Emma J, Edmondson, Richard J, Schlecht, Helene, Wallace, Andrew J, Jayson, Gordon C, Evans, D. Gareth R.

المصدر: Morgan , R D , Burghel , G J , Flaum , N , Bulman , M , Smith , P , Clamp , A R , Hasan , J , Mitchell , C , Salih , Z , Woodward , E R , Lalloo , F , Shaw , J , Desai , S , Crosbie , E J , Edmondson , R J , Schlecht , H , Wallace , A J , Jayson , G C & Evans , D G R 2023 , ' Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by ....

مصطلحات موضوعية: Biomarkers, Tumor, GENETICS, Ovarian Neoplasms, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

العلاقة: https://research.manchester.ac.uk/en/publications/8e8cea47-e434-4516-92a8-ca911dc7638eTest

الإتاحة: https://doi.org/10.1136/jcp-2022-208369Test
https://research.manchester.ac.uk/en/publications/8e8cea47-e434-4516-92a8-ca911dc7638eTest
https://pure.manchester.ac.uk/ws/files/222647754/_Manuscript_tBRCA_LR_v5.docxTest
https://pure.manchester.ac.uk/ws/files/299224715/_Manuscript_tBRCA_LR_v5.docxTest
http://www.scopus.com/inward/record.url?scp=85134517893&partnerID=8YFLogxKTest
https://www.mendeley.com/catalogue/f0b4bc28-8cbb-3b9b-a445-022fcc539057Test/
https://christie.openrepository.com/handle/10541/625390?show=fullTest

المؤلفون: Morgan, Robert d., Burghel, George j., Schlecht, Helene, Clamp, Andrew r., Hasan, Jurjees, Mitchell, Claire l., Salih, Zena, Shaw, Joseph, Desai, Sudha, Jayson, Gordon c., Woodward, Emma r., Evans, Gareth

المصدر: Morgan , R D , Burghel , G J , Schlecht , H , Clamp , A R , Hasan , J , Mitchell , C L , Salih , Z , Shaw , J , Desai , S , Jayson , G C , Woodward , E R & Evans , G 2023 , ' Real-World Concordance between Germline and Tumour BRCA1/2 Status in Epithelial Ovarian Cancer ' , Cancers , vol. 16 , no. 1 , 177 , pp. 177 . https://doi.org/10.3390/cancers16010177Test

مصطلحات موضوعية: ovarian cancer, germline, somatic, BRCA1, BRCA2

وصف الملف: application/pdf

العلاقة: https://research.manchester.ac.uk/en/publications/10bb6f0a-efe2-4d4a-8785-5492613fa380Test

الإتاحة: https://doi.org/10.3390/cancers16010177Test
https://research.manchester.ac.uk/en/publications/10bb6f0a-efe2-4d4a-8785-5492613fa380Test
https://pure.manchester.ac.uk/ws/files/290213661/cancers-16-00177_1_.pdfTest
https://www.mendeley.com/catalogue/2615bd7a-a865-3c68-9a0d-d55396b30eeeTest/

المؤلفون: Morgan, Robert D., Burghel, George J., Schlecht, Helene, Clamp, Andrew R., Hasan, Jurjees, Mitchell, Claire L., Salih, Zena, Shaw, Joseph, Desai, Sudha, Jayson, Gordon C., Woodward, Emma R., Evans, D. Gareth R.

المصدر: Cancers; Jan2024, Vol. 16 Issue 1, p177, 10p

مصطلحات موضوعية: GENETIC mutation, SEQUENCE analysis, SPECIALTY hospitals, DNA, BRCA genes, OVARIAN epithelial cancer, AGE distribution, GENETIC testing, MOLECULAR pathology, CANCER patients, CANCER treatment, STEM cells, DESCRIPTIVE statistics, RESEARCH funding, NUCLEIC acid amplification techniques

المؤلفون: Coulson-Gilmer, Camilla, Morgan, Robert D, Nelson, Louisa, Barnes, Bethany M, Tighe, Anthony, Wardenaar, René, Spierings, Diana C J, Schlecht, Helene, Burghel, George J, Foijer, Floris, Desai, Sudha, McGrail, Joanne C, Taylor, Stephen S

المصدر: Coulson-Gilmer , C , Morgan , R D , Nelson , L , Barnes , B M , Tighe , A , Wardenaar , R , Spierings , D C J , Schlecht , H , Burghel , G J , Foijer , F , Desai , S , McGrail , J C & Taylor , S S 2021 , ' Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models ' , Journal of Experimental and Clinical Cancer Research , vol. 40 , no. 1 , 323 . https://doi.org/10.1186/s13046-021-02124-0Test

مصطلحات موضوعية: High-grade serous ovarian cancer, PARG inhibitor, DNA replication, replication stress, gene expression signature, predictive biomarkers, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

العلاقة: https://research.manchester.ac.uk/en/publications/3009184a-46ef-47cd-a7dd-5cc084f7f707Test

الإتاحة: https://doi.org/10.1186/s13046-021-02124-0Test
https://research.manchester.ac.uk/en/publications/3009184a-46ef-47cd-a7dd-5cc084f7f707Test
https://pubmed.ncbi.nlm.nih.gov/34656146Test/

المؤلفون: Barnes, Bethany, Nelson, Louisa, Tighe, Anthony, Burghel, George, Lin, I-Hsuan, Desai, Sudha, Mcgrail, Joanne, Morgan, Robert D., Taylor, Stephen

المصدر: Barnes , B , Nelson , L , Tighe , A , Burghel , G , Lin , I-H , Desai , S , Mcgrail , J , Morgan , R D & Taylor , S 2021 , ' Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes ' , Genome Medicine , vol. 13 , no. 1 , 140 . https://doi.org/10.1186/s13073-021-00952-5Test

مصطلحات موضوعية: Ovarian cancer, Non-negative matrix factorization, RNA sequencing, subtype classification, machine-learning, transcriptomics, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

العلاقة: https://research.manchester.ac.uk/en/publications/9caf83d6-87a8-4cad-845e-44e665d42a11Test

الإتاحة: https://doi.org/10.1186/s13073-021-00952-5Test
https://research.manchester.ac.uk/en/publications/9caf83d6-87a8-4cad-845e-44e665d42a11Test
https://pubmed.ncbi.nlm.nih.gov/34470661Test/

المؤلفون: Barnes, Bethany M, Nelson, Louisa, Tighe, Anthony, Burghel, George J, Lin, I-Hsuan, Desai, Sudha, McGrail, Joanne C, Morgan, Robert D, Taylor, Stephen S

المصدر: essn: 1756-994X ; nlmid: 101475844 ; issn: 1756-994X

مصطلحات موضوعية: Ovarian cancer, Machine Learning, Transcriptomics, Rna Sequencing, Non-negative Matrix Factorization, Subtype Classification

العلاقة: https://chesterrep.openrepository.com/bitstream/handle/10034/626023/article.pdf?sequence=2Test; Genome medicine, volume 13, issue 1, page 140; http://hdl.handle.net/10034/626023Test

الإتاحة: http://hdl.handle.net/10034/626023Test
https://chesterrep.openrepository.com/bitstream/handle/10034/626023/article.pdf?sequence=2Test

المؤلفون: Nelson, Louisa, Tighe, Anthony, Golder, Anya, Littler, Samantha, Bakker, Bjorn, Moralli, Daniela, Baker, Syed Murtuza, Donaldson, Ian, Spierings, Diana C J, Wardenaar, Rene, Neale, Bethanie, Burghel, George, Winter-Roach, Brett, Edmondson, Richard, Clamp, Andrew, Jayson, Gordon, Desai, Sudha, Green , Catherine M, Hayes, Andrew, Foijer, Floris, Morgan, Robert, Taylor, Stephen

المصدر: Nelson , L , Tighe , A , Golder , A , Littler , S , Bakker , B , Moralli , D , Baker , S M , Donaldson , I , Spierings , D C J , Wardenaar , R , Neale , B , Burghel , G , Winter-Roach , B , Edmondson , R , Clamp , A , Jayson , G , Desai , S , Green , C M , Hayes , A , Foijer , F , Morgan , R & Taylor , S 2020 , ' A living biobank of ovarian ....

مصطلحات موضوعية: Biological Specimen Banks, Chromosomal Instability, Drug Resistance, Neoplasm, Female, Gene Expression, Gene Expression Profiling, Histological Techniques/methods, Humans, Imaging, Three-Dimensional, In Situ Hybridization, Fluorescence, In Vitro Techniques, Karyotyping, Mitosis/genetics, Models, Biological, Mutation, Ovarian Neoplasms/drug therapy, Paclitaxel/pharmacology, Single-Cell Analysis, Time-Lapse Imaging, Tumor Suppressor Protein p53/genetics, Whole Exome Sequencing, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1038/s41467-020-14551-2Test
https://research.manchester.ac.uk/en/publications/79403cc1-6efa-4aff-8a8c-2a70c9b003f2Test

المؤلفون: Morgan, Robert D., Burghel, George J., Flaum, Nicola, Bulman, Michael, Smith, Philip, Clamp, Andrew R., Hasan, Jurjees, Mitchell, Claire, Salih, Zena, Woodward, Emma R., Lalloo, Fiona, Shaw, Joseph, Desai, Sudha, Crosbie, Emma J., Edmondson, Richard J., Schlecht, Helene, Wallace, Andrew J., Jayson, Gordon C., Evans, Gareth R.

المصدر: Journal of Clinical Pathology; Oct2023, Vol. 76 Issue 10, p684-689, 6p

مصطلحات موضوعية: BREAST, OVARIAN epithelial cancer, TUMORS, NUCLEOTIDE sequencing, CLINICAL trials, DNA

المؤلفون: Deolet, Ellen, Arora, Iteeka, Van Dorpe, Jo, Van der Meulen, Joni, Desai, Sudha, Van Roy, Nadine, Kaur, Baljeet, Van de Vijver, Koen, McCluggage, W Glenn

المصدر: AMERICAN JOURNAL OF SURGICAL PATHOLOGY ; ISSN: 0147-5185 ; ISSN: 1532-0979

مصطلحات موضوعية: Medicine and Health Sciences, Ovary, mesonephric-like adenocarcinoma, extrauterine, immunohistochemistry, molecular, YOLK-SAC TUMOR, RECURRENT KRAS MUTATIONS, FEMALE GENITAL-TRACT, UTERINE CERVIX, CELL TUMOR, ADENOCARCINOMAS, CARCINOMA, BENIGN, OVERREPRESENTATION, TRISOMY-12

وصف الملف: application/pdf

العلاقة: https://biblio.ugent.be/publication/8714330Test; http://hdl.handle.net/1854/LU-8714330Test; http://dx.doi.org/10.1097/PAS.0000000000001766Test; https://biblio.ugent.be/publication/8714330/file/8714332Test

الإتاحة: https://doi.org/10.1097/PAS.0000000000001766Test
https://biblio.ugent.be/publication/8714330Test
http://hdl.handle.net/1854/LU-8714330Test
https://biblio.ugent.be/publication/8714330/file/8714332Test