دورية أكاديمية
Real-World Assessment of Efficacy and Safety Parameters for Dapagliflozin in Management of Type 2 Diabetes Mellitus: REWARD Study
| العنوان: | Real-World Assessment of Efficacy and Safety Parameters for Dapagliflozin in Management of Type 2 Diabetes Mellitus: REWARD Study |
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| المؤلفون: | Ahmed Hassoun, Denish Kumar Dhanwal, Jalal Nafach, Yasmin Ajaz, Asif Majid Khan, Abdullah Ben Nakhi, Monira AlArouj, Khadija Hafidh, Majdi AlNajjar, Ahmed Reyas, Sana Qamar, Mohamed Alsayed, Ahmad Bdair |
| المصدر: | Dubai Diabetes and Endocrinology Journal, Pp 1-10 (2022) |
| بيانات النشر: | Karger Publishers, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | dapagliflozin, sodium-glucose cotransporter type 2, sodium-glucose cotransporter type 2 inhibitors, diabetes mellitus, type 2 diabetes mellitus, type 2 diabetes, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | Introduction: While ample evidence on improved glycemic control, weight reduction, and lowered blood pressure (BP) with sodium-glucose cotransporter type 2 inhibitors (SGLT2is) exists, real-world data on the potential benefit of SGLT2i on the diabetic population in the Middle East are lacking. The aim of our study was to describe the glycemic control, changes in body weight, body mass index (BMI), lipid profile, and BPs in patients receiving dapagliflozin with other antidiabetic medication. Methods: The REWARD study was a multicenter, post-authorization, prospective, open-label, noninterventional, real-world, cohort study. We enrolled 511 adult, type 2 diabetes mellitus patients on antidiabetic medications. These patients were started on dapagliflozin and followed up for 1 year to assess changes in their clinical and laboratory outcomes. Results: The mean HbA1c decreased significantly from 8.5 ± 1.6% at baseline to 7.6 ± 1.3% after 12 months (p value |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2673-1797 2673-1738 |
| العلاقة: | https://www.karger.com/Article/FullText/519871Test; https://doaj.org/toc/2673-1797Test; https://doaj.org/toc/2673-1738Test |
| DOI: | 10.1159/000519871 |
| الوصول الحر: | https://doaj.org/article/059bfb4103f2495e97b4cf10defae7ccTest |
| رقم الانضمام: | edsdoj.059bfb4103f2495e97b4cf10defae7cc |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 26731797 26731738 |
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| DOI: | 10.1159/000519871 |