المؤلفون: Sigitas Mikutis, Muxin Gu, Erdem Sendinc, Madoka E. Hazemi, Hannah Kiely-Collins, Demetrios Aspris, George S. Vassiliou, Yang Shi, Konstantinos Tzelepis, Gonçalo J. L. Bernardes

المصدر: ACS Central Science, Vol 6, Iss 12, Pp 2196-2208 (2020)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2374-7951Test

الوصول الحر: https://doaj.org/article/4ce661e34b844c1e93d35c307107b2caTest

المؤلفون: Konstantinos Tzelepis, Etienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M. S. Vijayabaskar, Wen-Hsin Liu, Malgorzata Gozdecka, Emmanouil Metzakopian, Hamish D. Toop, Monika Dudek, Samuel C. Robson, Francisco Hermida-Prado, Yu Hsuen Yang, Roya Babaei-Jadidi, Dimitrios A. Garyfallos, Hannes Ponstingl, Joao M. L. Dias, Paolo Gallipoli, Michael Seiler, Silvia Buonamici, Binje Vick, Andrew J. Bannister, Roland Rad, Rab K. Prinjha, John C. Marioni, Brian Huntly, Jennifer Batson, Jonathan C. Morris, Cristina Pina, Allan Bradley, Irmela Jeremias, David O. Bates, Kosuke Yusa, Tony Kouzarides, George S. Vassiliou

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/1853a1ced0ff46dfaf75bec9896c8581Test

المؤلفون: Demetrios Aspris, Eliza Yankova, Konstantinos Tzelepis

المصدر: Current Opinion in Hematology. 28:80-85

مصطلحات موضوعية: 0301 basic medicine, biology, Myeloid leukemia, RNA, Hematology, 03 medical and health sciences, Haematopoiesis, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Epitranscriptomics, biology.protein, Cancer research, Demethylase, N6-Methyladenosine, Stem cell, Gene, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cf220a9d1aa2c00e47f5c6cdfd2f4e89Test
https://doi.org/10.1097/moh.0000000000000636Test

المؤلفون: Yusuke Tarumoto, Jonathan L. Cooper, Brian J. P. Huntly, George S. Vassiliou, Konstantinos Tzelepis, Xi Chen, Malgorzata Gozdecka, Demetrios Aspris, Muxin Gu, Etienne De Braekeleer, Kosuke Yusa, Jason S. L. Yu, Yan Zi Au, Swee Hoe Ong

المساهمون: Gu, Muxin [0000-0003-4376-795X], Tzelepis, Konstantinos [0000-0002-4865-7648], Huntly, Brian [0000-0003-0312-161X], Vassiliou, George [0000-0003-4337-8022], Apollo - University of Cambridge Repository

المصدر: Leukemia

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, BRD4, Lysine Acetyltransferases, Oncogene Proteins, Fusion, Apoptosis, Biology, Article, Epigenesis, Genetic, Histones, 03 medical and health sciences, Gene Knockout Techniques, 0302 clinical medicine, Cancer epigenetics, hemic and lymphatic diseases, Cell Line, Tumor, Transcriptional regulation, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, Myeloid Cells, KAT7, Promoter Regions, Genetic, neoplasms, Genetic Association Studies, Histone Acetyltransferases, Gene Rearrangement, Cancer stem cells, Myeloid leukemia, Disease Management, Cell Differentiation, Hematology, Histone-Lysine N-Methyltransferase, 3. Good health, Leukemia, Myeloid, Acute, 030104 developmental biology, Histone, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Myeloid-Lymphoid Leukemia Protein, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1f83a1b5c13994528ef8f7c7e96e47Test
http://europepmc.org/articles/PMC7610570Test

المؤلفون: Esteban A. Orellana, Eric S. Fischer, Mehdi Pirouz, Demetrios Aspris, Jihoon Lim, George S. Vassiliou, Konstantinos Tzelepis, Richard I. Gregory, Etienne De Braekeleer, Gonçalo J. L. Bernardes, Qi Liu, Alejandro Gutierrez, Erdem Sendinc, Muxin Gu, Sigitas Mikutis, Frank J. Slack, Wen Cai Zhang, Eliza Yankova, Allan Bradley, Raja Hussain Ali, Dimitrios A. Garyfallos

المصدر: Mol Cell

مصطلحات موضوعية: TRNA modification, Methyltransferase, Cell, RNA, Translation (biology), Cell Biology, Biology, Cell cycle, Article, Cell biology, medicine.anatomical_structure, RNA, Transfer, GTP-Binding Proteins, Epitranscriptomics, Neoplasms, Transfer RNA, medicine, Humans, RNA, Messenger, RNA Processing, Post-Transcriptional, Molecular Biology, Ribosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e86d4daac3626d82c187ece2288d8daTest
https://europepmc.org/articles/PMC8380730Test/

المؤلفون: Etienne De Braekeleer, Patrick Guest, Maria Eleftheriou, Georgia Tsagkogeorga, Ewa S. Pilka, Nerea Irigoyen, Malgorzata Gozdecka, Tony Kouzarides, Binje Vick, Andrew J. Bannister, Richard Fosbeary, Mark Albertella, Justyna Rak, Alan G. Hendrick, Irmela Jeremias, Dan Leggate, Demetrios Aspris, George S. Vassiliou, Eliza Yankova, Oliver Rausch, Natalie A. Webster, Konstantinos Tzelepis, Byron Andrews, João Lopes Dias, Wesley Blackaby

المساهمون: Yankova, Eliza [0000-0003-2913-0012], Pilka, Ewa S [0000-0002-0107-2597], Hendrick, Alan G [0000-0002-8604-0462], Irigoyen, Nerea [0000-0001-6346-3369], Dias, Joao ML [0000-0002-8451-3537], Bannister, Andrew J [0000-0002-6312-4436], Vick, Binje [0000-0003-1956-2778], Jeremias, Irmela [0000-0003-1773-7677], Vassiliou, George S [0000-0003-4337-8022], Rausch, Oliver [0000-0003-4074-3848], Tzelepis, Konstantinos [0000-0002-4865-7648], Kouzarides, Tony [0000-0002-8918-4162], Apollo - University of Cambridge Repository

المصدر: Nature 593, 597-601 (2021)
Nature

مصطلحات موضوعية: Methyltransferase, Adenosine, Antineoplastic Agents, Apoptosis, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Cell Line, Tumor, Animals, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, Molecular Structure, Gene Expression Regulation, Leukemic, RNA, Cell Differentiation, Methyltransferases, Small molecule, Xenograft Model Antitumor Assays, 3. Good health, Mice, Inbred C57BL, Leukemia, Myeloid, Acute, Enzyme, chemistry, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Stem cell

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d210f07dd025da467c48c4ac96a2015Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61877Test

المؤلفون: Erdem Sendinc, George S. Vassiliou, Yang Shi, Konstantinos Tzelepis, Gonçalo J. L. Bernardes, Hannah Kiely-Collins, Madoka E Hazemi, Sigitas Mikutis, Muxin Gu, Demetrios Aspris

المساهمون: Mikutis, Sigitas [0000-0003-0064-639X], Vassiliou, George [0000-0003-4337-8022], Tzelepis, Konstantinos [0000-0002-4865-7648], Lopes Bernardes, Goncalo [0000-0001-6594-8917], Apollo - University of Cambridge Repository, Repositório da Universidade de Lisboa

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ACS Central Science, Vol 6, Iss 12, Pp 2196-2208 (2020)
ACS Central Science

مصطلحات موضوعية: 34 Chemical Sciences, 010405 organic chemistry, Chemistry, RNA methylation, General Chemical Engineering, 1.1 Normal biological development and functioning, RNA, General Chemistry, Computational biology, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, 3. Good health, RNA interference, RNA editing, RNA splicing, RNA methyltransferase activity, Nucleic acid, Genetics, 1 Underpinning research, RNA Cleavage, Generic health relevance, QD1-999, Research Article

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4712067cbb57e56d88e6f906f5727d6fTest

المؤلفون: Emmanouil Metzakopian, Demetrios Aspris, Paolo Gallipoli, Tony Kouzarides, Francisco Hermida-Prado, Rab K. Prinjha, Isaia Barbieri, Roya Babaei-Jadidi, Samuel Robson, Irmela Jeremias, John C. Marioni, Michael Seiler, João M. L. Dias, Cristina Pina, Kosuke Yusa, Malgorzata Gozdecka, Silvia Buonamici, Yu Hsuen Yang, Etienne De Braekeleer, Brian J. P. Huntly, Allan Bradley, Binje Vick, Andrew J. Bannister, Hannes Ponstingl, Monika Dudek, Hamish D. Toop, M. S. Vijayabaskar, David O. Bates, Wen-Hsin Liu, George S. Vassiliou, Jennifer Batson, Jonathan C. Morris, Dimitrios A. Garyfallos, Konstantinos Tzelepis, Roland Rad

المساهمون: Toop, Hamish D [0000-0003-4637-4764], Ponstingl, Hannes [0000-0001-7573-1703], Dias, Joao ML [0000-0002-8451-3537], Gallipoli, Paolo [0000-0001-7254-2253], Vick, Binje [0000-0003-1956-2778], Prinjha, Rab K [0000-0002-2666-3326], Marioni, John C [0000-0001-9092-0852], Huntly, Brian [0000-0003-0312-161X], Batson, Jennifer [0000-0001-7005-4336], Morris, Jonathan C [0000-0002-5109-9069], Jeremias, Irmela [0000-0003-1773-7677], Vassiliou, George S [0000-0003-4337-8022], Apollo - University of Cambridge Repository

المصدر: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nat. Commun. 9:5378 (2018)
Tzelepis, K, De Braekeleer, E, Aspris, D, Barbieri, I, Vijayabaskar, M S, Liu, W, Gozdecka, M, Metzakopian, E, Toop, H D, Dudek, M, Robson, S C, Hermida-Prado, F, Yang, Y H, Babaei-Jadidi, R, Garyfallos, D A, Ponstingl, H, Dias, J M L, Gallipoli, P, Seiler, M, Buonamici, S, Vick, B, Bannister, A J, Rad, R, Prinjha, R K, Marioni, J C, Huntly, B, Batson, J, Morris, J C, Pina, C, Bradley, A, Jeremias, I, Bates, D O, Yusa, K, Kouzarides, T & Vassiliou, G S 2018, ' SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 ', Nature Communications, vol. 9, no. 1, 5378 . https://doi.org/10.1038/s41467-018-07620-0Test

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, BRD4, Cellular differentiation, Science, RNA Splicing, General Physics and Astronomy, Cell Cycle Proteins, HL-60 Cells, Biology, SRPK1, Protein Serine-Threonine Kinases, General Biochemistry, Genetics and Molecular Biology, Article, Epigenesis, Genetic, Paediatric cancer, 03 medical and health sciences, Targeted therapies, Cancer epigenetics, hemic and lymphatic diseases, Humans, Protein Isoforms, MYB, Epigenetics, lcsh:Science, neoplasms, Multidisciplinary, Biomedical Sciences, Myeloid leukemia, Nuclear Proteins, Cell Differentiation, General Chemistry, Cell Cycle Checkpoints, Chromatin, 3. Good health, Hematopoiesis, Leukemia, Myeloid, Acute, 030104 developmental biology, Cancer research, lcsh:Q, K562 Cells, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b977c8316956d534c8b30c77125f51fTest
http://europepmc.org/articles/PMC6300607Test

المؤلفون: George S. Vassiliou, Eliza Yankova, Etienne De Braekeleer, Oliver Rausch, Yaara Ofir-Rosenfeld, Richard Fosbeary, Alexandra Sapetschnig, Mark Albertella, Tony Kouzarides, Dan Leggate, Demetrios Aspris, Alan G. Hendrick, Cristina Pina, Konstantinos Tzelepis, Ana Filipa Domingues, Justyna Rak, Wesley Blackaby

المصدر: Blood. 134:403-403

مصطلحات موضوعية: 0301 basic medicine, Myeloid, Methyltransferase, Chemistry, Immunology, RNA, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Biochemistry, Transplantation, 03 medical and health sciences, Haematopoiesis, Leukemia, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, In vivo, medicine, Cancer research, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cad2a8c3b3a4c7a25f2b1f2eaaed797fTest
https://doi.org/10.1182/blood-2019-127962Test

المؤلفون: Namshik Han, Samuel Robson, Etienne De Braekeleer, Luca Pandolfini, Hannes Ponstingl, Junwei Shi, Konstantinos Tzelepis, Tony Kouzarides, Alan G. Hendrick, Valentina Migliori, Demetrios Aspris, Isaia Barbieri, George S. Vassiliou, Christopher R. Vakoc, Andrew J. Bannister, Gonzalo Millán-Zambrano

المساهمون: Barbieri, Isaia [0000-0003-3035-8970], Tzelepis, Konstantinos [0000-0002-4865-7648], Pandolfini, Luca [0000-0003-1444-8167], Bannister, Andrew [0000-0002-6312-4436], Han, Namshik [0000-0002-7741-6384], Hendrick, Alan [0000-0002-8604-0462], Vassiliou, George [0000-0003-4337-8022], Kouzarides, Tony [0000-0002-8918-4162], Apollo - University of Cambridge Repository

مصطلحات موضوعية: 0301 basic medicine, Myeloid, Adenosine, Biology, Article, 03 medical and health sciences, Mice, Cell Line, Tumor, medicine, Coding region, Animals, Humans, RNA, Messenger, Promoter Regions, Genetic, Gene, Cell Proliferation, Genetics, Regulation of gene expression, Multidisciplinary, Methyltransferase complex, MRNA modification, Methyltransferases, Chromatin, Cell biology, Gene Expression Regulation, Neoplastic, Leukemia, Myeloid, Acute, 030104 developmental biology, medicine.anatomical_structure, Essential gene, Protein Biosynthesis, Female, CRISPR-Cas Systems, Transcription Initiation Site, Ribosomes, Genes, Neoplasm

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38de288bed5c391918c246d11bf98647Test