يعرض 1 - 10 نتائج من 83 نتيجة بحث عن '"Deborah H. Charych"', وقت الاستعلام: 1.26s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy

    المؤلفون: Meenu Sharma, Hiep Khong, Faisal Fa’ak, Salah-Eddine Bentebibel, Louise M. E. Janssen, Brent C. Chesson, Caitlin A. Creasy, Marie-Andrée Forget, Laura Maria S. Kahn, Barbara Pazdrak, Binisha Karki, Yared Hailemichael, Manisha Singh, Christina Vianden, Srinivas Vennam, Uddalak Bharadwaj, David J. Tweardy, Cara Haymaker, Chantale Bernatchez, Shixia Huang, Kimal Rajapakshe, Cristian Coarfa, Michael E. Hurwitz, Mario Sznol, Patrick Hwu, Ute Hoch, Murali Addepalli, Deborah H. Charych, Jonathan Zalevsky, Adi Diab, Willem W. Overwijk

    المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    العلاقة: https://doaj.org/toc/2041-1723Test

    الوصول الحر: https://doaj.org/article/ef1801862b2840b0a440db03c657db66Test

    View record in DOAJ النص الكامل

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  2. 2
    دورية أكاديمية
    Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion

    المؤلفون: Jonathan Zalevsky, Deborah H Charych, Alfredo Nicosia, Fulvia Troise, Anna Morena D'Alise, Guido Leoni, Maria De Lucia, Francesca Langone, Linda Nocchi, Fabio Giovanni Tucci, Elisa Micarelli, Gabriella Cotugno, Irene Garzia, Rosa Vitale, Veronica Bignone, Elena Di Matteo, Rosa Bartolomeo, Armin Lahm, Elisa Scarselli

    المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)

    مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

    العلاقة: https://jitc.bmj.com/content/9/11/e003480.fullTest; https://doaj.org/toc/2051-1426Test; https://doaj.org/article/d728620d3f7a4b82b56909660ec7e6fbTest

    الإتاحة: https://doi.org/10.1136/jitc-2021-003480Test
    https://doaj.org/article/d728620d3f7a4b82b56909660ec7e6fbTest

    View record in BASE النص الكامل

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  3. 3
    دورية أكاديمية
    Combination of radiation therapy, bempegaldesleukin, and checkpoint blockade eradicates advanced solid tumors and metastases in mice

    المؤلفون: Willem W Overwijk, Zachary S Morris, Paul M Sondel, Deborah H Charych, Amy K Erbe, Jacquelyn A Hank, Alexander L Rakhmilevich, Won Jong Jin, Peter M Carlson, Alexander A Pieper, Ravi B Patel, Daniel V Spiegelman, Jen Birstler

    المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)

    مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

    العلاقة: https://jitc.bmj.com/content/9/6/e002715.fullTest; https://doaj.org/toc/2051-1426Test; https://doaj.org/article/07a432011bbe452ebe7af0fdcf7d01a3Test

    الإتاحة: https://doi.org/10.1136/jitc-2021-002715Test
    https://doaj.org/article/07a432011bbe452ebe7af0fdcf7d01a3Test

    View record in BASE النص الكامل

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  4. 4
    Figure S2 from NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models

    المؤلفون: Stephen K. Doberstein, Seema S. Kantak, Theresa D. Sweeney, Jicai Huang, Yujun Wang, Chunmei Ji, Yolanda M. Kirksey, Rupesh S. Kanhere, Rhoneil L. Pena, Marina Konakova, Thomas K. Chang, Cherie F. Ali, Laurie A. VanderVeen, Paul W. Sims, Xiaofeng Liu, Dawei Sheng, Peter B. Kirk, Murali K. Addepalli, Steve R. Lee, John L. Langowski, Ute Hoch, Deborah H. Charych

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134c32d3a79528e455bdc621b359c574Test
    https://doi.org/10.1158/1078-0432.22460627.v1Test


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  5. 5
    Data from NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models

    المؤلفون: Stephen K. Doberstein, Seema S. Kantak, Theresa D. Sweeney, Jicai Huang, Yujun Wang, Chunmei Ji, Yolanda M. Kirksey, Rupesh S. Kanhere, Rhoneil L. Pena, Marina Konakova, Thomas K. Chang, Cherie F. Ali, Laurie A. VanderVeen, Paul W. Sims, Xiaofeng Liu, Dawei Sheng, Peter B. Kirk, Murali K. Addepalli, Steve R. Lee, John L. Langowski, Ute Hoch, Deborah H. Charych

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fe8117f5e79650581c47831ffd8438Test
    https://doi.org/10.1158/1078-0432.c.6524552Test


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  6. 6
    Supplemental Data from NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models

    المؤلفون: Stephen K. Doberstein, Seema S. Kantak, Theresa D. Sweeney, Jicai Huang, Yujun Wang, Chunmei Ji, Yolanda M. Kirksey, Rupesh S. Kanhere, Rhoneil L. Pena, Marina Konakova, Thomas K. Chang, Cherie F. Ali, Laurie A. VanderVeen, Paul W. Sims, Xiaofeng Liu, Dawei Sheng, Peter B. Kirk, Murali K. Addepalli, Steve R. Lee, John L. Langowski, Ute Hoch, Deborah H. Charych

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0355aa629ebbad4322a3a47b80293276Test
    https://doi.org/10.1158/1078-0432.22460618Test


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  7. 7
    Combination of radiation therapy, bempegaldesleukin, and checkpoint blockade eradicates advanced solid tumors and metastases in mice

    المؤلفون: Zachary S. Morris, Willem W. Overwijk, Deborah H. Charych, Jacquelyn A. Hank, Alexander L. Rakhmilevich, Alexander A. Pieper, Won Jong Jin, Jen Birstler, Paul M. Sondel, Daniel V Spiegelman, Ravi Patel, Amy K. Erbe, Peter M. Carlson

    المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
    Journal for Immunotherapy of Cancer

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, combined modality therapy, medicine.medical_treatment, Receptor expression, Immunology, Polyethylene Glycols, Metastasis, Mice, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, Immunology and Allergy, Neoplasm Metastasis, Immune Checkpoint Inhibitors, RC254-282, Clinical/Translational Cancer Immunotherapy, Pharmacology, Radiotherapy, business.industry, Melanoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunotherapy, medicine.disease, costimulatory and inhibitory T-cell receptors, Primary tumor, Head and neck squamous-cell carcinoma, cytokines, Immune checkpoint, Radiation therapy, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, translational medical research, Cancer research, Interleukin-2, Molecular Medicine, Female, business

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b3a8b55b3fe3c50b61ffaf39069fc4Test
    https://jitc.bmj.com/content/9/6/e002715.fullTest


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  8. 8
    Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion

    المؤلفون: Deborah H. Charych, Elena Di Matteo, Anna Morena D'Alise, Gabriella Cotugno, Maria De Lucia, Veronica Bignone, Fabio Giovanni Tucci, Guido Leoni, Rosa Bartolomeo, Elisa Scarselli, Elisa Micarelli, Jonathan Zalevsky, Alfredo Nicosia, Linda Nocchi, Francesca Langone, Rosa Maria Vitale, Fulvia Troise, Irene Garzia, Armin Lahm

    المساهمون: D'Alise, A. M., Leoni, G., de Lucia, M., Langone, F., Nocchi, L., Tucci, F. G., Micarelli, E., Cotugno, G., Troise, F., Garzia, I., Vitale, R., Bignone, V., Matteo, E. D., Bartolomeo, R., Charych, D. H., Lahm, A., Zalevsky, J., Nicosia, A., Scarselli, E.

    المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
    Journal for Immunotherapy of Cancer

    مصطلحات موضوعية: Cancer Research, combined modality therapy, medicine.medical_treatment, T cell, Programmed Cell Death 1 Receptor, Immunology, Gene Expression, chemical and pharmacologic phenomena, Cancer Vaccines, T-Lymphocytes, Regulatory, Mice, Immune system, medicine, Animals, Humans, tumor microenvironment, Immunology and Allergy, RC254-282, Pharmacology, Tumor microenvironment, Animal, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cancer, Basic Tumor Immunology, adaptive immunity, Immunotherapy, vaccination, medicine.disease, Acquired immune system, Vaccination, medicine.anatomical_structure, Oncology, Cancer cell, Cancer research, Molecular Medicine, Female, business, Cancer Vaccine, Human

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ff8da7288e6c86135e2a0a4e5c196aTest
    https://doi.org/10.1136/jitc-2021-003480Test


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  9. 9
    NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8+ T cell responses capable of curing multi-focal cancer

    المؤلفون: Annah S Rolig, Ute Hoch, Deborah H. Charych, Melissa J Kasiewicz, Michael J. McNamara, Daniel Rose, Joshua M. Walker, William L. Redmond, Ian Hilgart-Martiszus

    المصدر: Journal for Immunotherapy of Cancer
    Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

    مصطلحات موضوعية: Cancer Research, Combination therapy, medicine.medical_treatment, T cell, Fibrosarcoma, Immunology, immunity, cellular, CD8-Positive T-Lymphocytes, T-Lymphocytes, Regulatory, Natural killer cell, Polyethylene Glycols, Mice, Immune system, Lymphocytes, Tumor-Infiltrating, Immunology and Allergy, Medicine, Cytotoxic T cell, Animals, RC254-282, T-lymphocytes, Pharmacology, Mice, Inbred BALB C, Radiotherapy, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Basic Tumor Immunology, Immunotherapy, Combined Modality Therapy, Radiation therapy, Mice, Inbred C57BL, medicine.anatomical_structure, Oncology, Cancer research, Molecular Medicine, Interleukin-2, Female, Sarcoma, Experimental, business, Colorectal Neoplasms, CD8

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6ed4cbf4654493c723ce6af7f2a728Test
    http://europepmc.org/articles/PMC7252958Test


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  10. 10
    Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy

    المؤلفون: Marie Andrée Forget, Barbara Pazdrak, Yared Hailemichael, Meenu Sharma, Patrick Hwu, Cara Haymaker, Adi Diab, Binisha Karki, Ute Hoch, Christina Vianden, Deborah H. Charych, Manisha Singh, Caitlin Creasy, Cristian Coarfa, Michael E. Hurwitz, Salah Eddine Bentebibel, Mario Sznol, Uddalak Bharadwaj, Hiep Khong, Kimal Rajapakshe, Chantale Bernatchez, David J. Tweardy, Jonathan Zalevsky, Murali Addepalli, Srinivas Vennam, Faisal Fa’ak, Willem W. Overwijk, Shixia Huang, Louise M.E. Janssen, Brent C. Chesson, Laura Maria S. Kahn

    المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
    Nature Communications

    مصطلحات موضوعية: 0301 basic medicine, Cancer therapy, medicine.medical_treatment, General Physics and Astronomy, CD8-Positive T-Lymphocytes, Lymphocyte Activation, T-Lymphocytes, Regulatory, Polyethylene Glycols, Cohort Studies, Mice, 0302 clinical medicine, Prodrugs, Lymphocytes, lcsh:Science, Receptor, Melanoma, Multidisciplinary, 3. Good health, Cytokine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Monoclonal, Tumour immunology, Cytokines, Drug Therapy, Combination, Female, Immunotherapy, medicine.symptom, Science, T cell, Antibodies, Monoclonal, Humanized, Article, General Biochemistry, Genetics and Molecular Biology, Interferon-gamma, 03 medical and health sciences, medicine, Animals, Humans, Carcinoma, Renal Cell, Tumor Necrosis Factor-alpha, business.industry, Cancer, Receptors, Interleukin-2, General Chemistry, medicine.disease, Ipilimumab, Blockade, Mice, Inbred C57BL, 030104 developmental biology, Mechanism of action, Cancer research, Interleukin-2, lcsh:Q, business, CD8

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0572cdd81af8649d8def3ef23f546b8Test
    https://doi.org/10.1038/s41467-020-14471-1Test


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