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1دورية أكاديمية
المؤلفون: Jialu Wang, Kenji Hanada, Dean P. Staus, Michael A. Makara, Giri Raj Dahal, Qiang Chen, Andrea Ahles, Stefan Engelhardt, Howard A. Rockman
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
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المؤلفون: Paula K. Rambarat, Biswaranjan Pani, Robert J. Lefkowitz, Shashank Vege, Seungkirl Ahn, Dean P. Staus, Bruno N. Valan, Tommaso Costa, Alem W. Kahsai, Andrew Liu
المصدر: Molecular Pharmacology. 100:513-525
مصطلحات موضوعية: Pharmacology, Allosteric modulator, genetic structures, Chemistry, Allosteric regulation, Cooperative binding, Small molecule, medicine, Arrestin, Molecular Medicine, Receptor, Carvedilol, medicine.drug, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3c7ae1a5d7fc7bdd6a4374179ff46d40Test
https://doi.org/10.1124/molpharm.121.000363Test -
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المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Receptors, Vasopressin, Allosteric regulation, Proto-Oncogene Mas, Biochemistry, Substrate Specificity, src Homology Domains, 03 medical and health sciences, GPCR, G protein-coupled receptors, Arrestin, Humans, Phosphorylation, Molecular Biology, G protein-coupled receptor, Receptor, Muscarinic M2, 030102 biochemistry & molecular biology, arrestin, Chemistry, Autophosphorylation, Signal transducing adaptor protein, Cell Biology, Recombinant Proteins, allosteric regulation, Nanostructures, Cell biology, Enzyme Activation, Kinetics, beta-Arrestin 1, src-Family Kinases, 030104 developmental biology, Mutagenesis, Site-Directed, Enzymology, Arrestin beta 2, Receptors, Adrenergic, beta-2, Signal transduction, Peptides, Protein Binding, Signal Transduction, Src, Proto-oncogene tyrosine-protein kinase Src
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3fca8f534076fed69ccead04aa47ffTest
https://doi.org/10.1074/jbc.ra120.015400Test -
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المؤلفون: Wayne L. Hubbell, Andrew C. Kruse, Robert J. Lefkowitz, Conor McMahon, Howard A. Rockman, Matthias Elgeti, Laura M. Wingler, Jialu Wang, Meredith A. Skiba, Dean P. Staus
المصدر: Proc Natl Acad Sci U S A
مصطلحات موضوعية: Angiotensin receptor, Receptors, Angiotensin, Multidisciplinary, biology, Chemistry, Antibody Affinity, Blood Pressure, Single-Domain Antibodies, Biological Sciences, Pharmacology, Angiotensin II, Cell Line, Angiotensin Receptor Antagonists, Mice, Chemokine receptor, Losartan, Renin–angiotensin system, medicine, biology.protein, Animals, Humans, Antibody, Receptor, medicine.drug, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b35f906b7b9631e5554ad558505ea4Test
https://doi.org/10.1073/pnas.2009029117Test -
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المؤلفون: Robert J. Lefkowitz, Alissa L. W. Kleinhenz, Meredith A. Skiba, Andrew C. Kruse, Carl-Mikael Suomivuori, Conor McMahon, Dean P. Staus, Ron O. Dror, Naomi R. Latorraca, Laura M. Wingler
المصدر: Science
مصطلحات موضوعية: Multidisciplinary, biology, Protein Conformation, Chemistry, Angiotensin II, Ligands, Receptor, Angiotensin, Type 1, Article, Cell biology, Chemokine receptor, Gq alpha subunit, Heterotrimeric G protein, biology.protein, Humans, Signal transduction, Receptor, beta-Arrestins, Endogenous agonist, Signal Transduction, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6a468f15f31a04e563eca4ab612dd6Test
https://doi.org/10.1126/science.aay9813Test -
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المؤلفون: Robert J. Lefkowitz, William D. Capel, Michael J. Robertson, Georgios Skiniotis, Alissa L. W. Kleinhenz, Dean P. Staus, Naomi R. Latorraca, Laura M. Wingler, Hongli Hu
المصدر: Nature
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Cell signaling, G protein, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Heterotrimeric G protein, Arrestin, Humans, Computer Simulation, Lipid bilayer, beta-Arrestins, Nanodisc, G protein-coupled receptor, Multidisciplinary, Chemistry, Cryoelectron Microscopy, Lipids, Nanostructures, Protein Structure, Tertiary, 030104 developmental biology, Biophysics, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1efd599fe56055577c922d7be1c08c5Test
https://doi.org/10.1038/s41586-020-1954-0Test -
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المؤلفون: Biswaranjan, Pani, Seungkirl, Ahn, Paula K, Rambarat, Shashank, Vege, Alem W, Kahsai, Andrew, Liu, Bruno N, Valan, Dean P, Staus, Tommaso, Costa, Robert J, Lefkowitz
المصدر: Molecular pharmacology. 100(5)
مصطلحات موضوعية: HEK293 Cells, Allosteric Regulation, Dose-Response Relationship, Drug, Adrenergic beta-Antagonists, Sf9 Cells, Animals, Humans, Carvedilol, Receptors, Adrenergic, beta-2, beta-Arrestins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::a25ba5f5598267b2a18bff03e4dc43d9Test
https://pubmed.ncbi.nlm.nih.gov/34862306Test -
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المؤلفون: Claudia Lee, Jeffrey S. Smith, Dean P. Staus, Sudarshan Rajagopal, Thomas F. Pack, Issac Choi, Xinyu Xiong, Zhiyuan Ma, Dylan Eiger, Ian M. Levitan, Gayathri Viswanathan, Alem W. Kahsai, Kevin Zheng, Joshua C. Snyder, Marc G. Caron, Anmol Warman, Asuka Inoue, Lauren K. Rochelle
المصدر: Science. 371
مصطلحات موضوعية: Multidisciplinary, Chemistry, G protein, GTP-Binding Protein alpha Subunits, Heterotrimeric G protein, Gi alpha subunit, Arrestin, Signal transducing adaptor protein, Signal transduction, G protein-coupled receptor, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::44854b6d99141f5ba0b875f6d96fb686Test
https://doi.org/10.1126/science.aay1833Test -
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المؤلفون: Xiangyu Liu, Ali Masoudi, Alem W. Kahsai, Li-Yin Huang, Biswaranjan Pani, Dean P. Staus, Paul J. Shim, Kunio Hirata, Rishabh K. Simhal, Allison M. Schwalb, Paula K. Rambarat, Seungkirl Ahn, Robert J. Lefkowitz, Brian Kobilka
المصدر: Science. 364:1283-1287
مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Multidisciplinary, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4c865d47044825bfbfb594df9185fc57Test
https://doi.org/10.1126/science.aaw8981Test -
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المؤلفون: Laura M. Wingler, Biswaranjan Pani, Dean P. Staus, Paula K. Rambarat, Paul J. Shim, Robert J. Lefkowitz, Jin Lei, Thomas Franch, Mikkel Vestergaard, Lillian D. Sun, Eva Kampmann Olsen, Thomas T. Xu, Li-Yin Huang, Shuai Zhao, Seungkirl Ahn, Gitte Nystrup Husemoen, Alem W. Kahsai, Rishabh K. Simhal, Xin Chen
المصدر: Molecular Pharmacology
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, G protein, Allosteric regulation, Substrate Specificity, Small Molecule Libraries, 03 medical and health sciences, Structure-Activity Relationship, Allosteric Regulation, GTP-Binding Proteins, Structure–activity relationship, Receptor, Adrenergic beta-2 Receptor Agonists, G protein-coupled receptor, Gene Library, Pharmacology, Molecular Structure, Chemistry, Drug discovery, Cooperative binding, Drug Synergism, Articles, Small molecule, 3. Good health, 030104 developmental biology, beta-Arrestin 1, Molecular Medicine, Receptors, Adrenergic, beta-2, Allosteric Site
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8cb23648cdfae42cf2c744bde85237Test
http://europepmc.org/articles/PMC6022804Test