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1صورة
المؤلفون: Devi Kasinathan, Zheng Guo, Dylan C. Sarver, G. William Wong, Shumei Yun, Aaron W. Michels, Liping Yu, Chandan Sona, Matthew N. Poy, Maria L. Golson, Dax Fu
مصطلحات موضوعية: Other biological sciences not elsewhere classified, Type 1 Diabetes, Monoclonal Antibodies, Immunotherapy, ZnT-8 (zinc transporter), NOD Mouse/Mice, Islet Autoimmunity, Antigen Identification, Autoantibody/Autoantibodies, Beta Cell Autoimmunity
الإتاحة: https://doi.org/10.2337/figshare.25254211.v1Test
https://figshare.com/articles/figure/Cell-surface_ZnT8_antibody_prevents_and_reverses_autoimmune_diabetes_in_mice/25254211Test -
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المؤلفون: Zheng Guo, Devi Kasinathan, Chengfeng Merriman, Maki Nakayama, Hua Li, Huilin Li, Cheng Xu, G. William Wong, Liping Yu, Maria L. Golson, Dax Fu
المصدر: Diabetes.
مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Internal Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094967013bf4518c824f6c946b481e46Test
https://pubmed.ncbi.nlm.nih.gov/36448936Test -
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المؤلفون: Chengfeng Merriman, Dax Fu
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, medicine.medical_treatment, Down-Regulation, Inflammation, Zinc Transporter 8, Endoplasmic Reticulum, Biochemistry, Proinflammatory cytokine, Islets of Langerhans, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, medicine, Humans, Insulin, Molecular Biology, 030102 biochemistry & molecular biology, Chemistry, Endoplasmic reticulum, Molecular Bases of Disease, Cell Biology, Endoplasmic Reticulum Stress, Cell biology, Pancreatic Neoplasms, Protein Transport, 030104 developmental biology, Cytokine, Apoptosis, Gene Knockdown Techniques, Unfolded protein response, Cytokines, Insulinoma, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a922355eae5fd0bd6f4d813818008eTest
https://doi.org/10.1074/jbc.ra119.010937Test -
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المؤلفون: Xiaofan Jia, Yong Gu, Janet M. Wenzlau, Hua Li, Marian Rewers, Chengfeng Merriman, Huilin Li, Zheng Guo, Dax Fu, Liping Yu
المصدر: J Autoimmun
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Adolescent, Immunology, Disease, Zinc Transporter 8, medicine.disease_cause, Autoantigens, Epitope, Article, Autoimmunity, 03 medical and health sciences, Islets of Langerhans, Young Adult, 0302 clinical medicine, medicine, Immunology and Allergy, Humans, Longitudinal Studies, Child, Aged, Autoantibodies, 030203 arthritis & rheumatology, Autoimmune disease, Antibody-dependent cell-mediated cytotoxicity, Type 1 diabetes, business.industry, Pancreatic islets, Autoantibody, Infant, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Diabetes Mellitus, Type 1, Seroconversion, Child, Preschool, Epitopes, B-Lymphocyte, Female, business, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73518bb7cb427268b2a597f0f83c5863Test
https://pubmed.ncbi.nlm.nih.gov/34130115Test -
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المؤلفون: Cynthia L. Sears, Richard B. Thompson, Mark Donowitz, Dax Fu, Fengyi Wan, Ruxian Lin, Joanna M.P. Melia, Ramnik J. Xavier
المصدر: Biochemical and Biophysical Research Communications. 515:325-331
مصطلحات موضوعية: 0301 basic medicine, Biophysics, Inflammation, Polymorphism, Single Nucleotide, Biochemistry, Interferon-gamma, 03 medical and health sciences, 0302 clinical medicine, Immune system, Crohn Disease, medicine, Homeostasis, Humans, Interferon gamma, RNA, Messenger, Interleukin 8, Intestinal Mucosa, Cation Transport Proteins, Molecular Biology, Lamina propria, Tumor Necrosis Factor-alpha, Chemistry, NF-kappa B, Epithelial Cells, Cell Biology, Recombinant Proteins, Up-Regulation, Cell biology, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Tumor necrosis factor alpha, Calprotectin, medicine.symptom, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1168f6d2f4d348e05d5b1490c6dc87Test
https://doi.org/10.1016/j.bbrc.2019.05.137Test -
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المؤلفون: Dax Fu, Chengfeng Merriman, Huilin Li, Hua Li
المصدر: Journal of Biological Chemistry. 293:16206-16216
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Allosteric regulation, Zinc Transporter 8, Monoclonal antibody, Biochemistry, Epitope, 03 medical and health sciences, Allosteric Regulation, Insulin-Secreting Cells, Drug Discovery, medicine, Humans, Genetic Predisposition to Disease, Molecular Biology, 030102 biochemistry & molecular biology, SLC30A8, biology, Chemistry, Drug discovery, Methods and Resources, Antibodies, Monoclonal, Transporter, Cell Biology, Solute carrier family, 030104 developmental biology, Diabetes Mellitus, Type 2, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f37bec8d7ed49a9eaa932e9133f1cfTest
https://doi.org/10.1074/jbc.ra118.005136Test -
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المؤلفون: Janet M. Wenzlau, Hua Li, Yong Gu, Chengfeng Merriman, Huilin Li, Xiaofan Jia, Marian Rewers, Dax Fu, Liping Yu
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Autoimmune disease, geography, Type 1 diabetes, geography.geographical_feature_category, business.industry, Pancreatic islets, Autoantibody, medicine.disease, Institutional review board, Islet, medicine.disease_cause, Epitope, Autoimmunity, medicine.anatomical_structure, Immunology, medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6a2cd33624ae26cff5de391f87d913a3Test
https://doi.org/10.2139/ssrn.3754816Test -
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المؤلفون: Dax Fu, Qiong Huang, Wei Gu, Liping Yu, Chengfeng Merriman
المصدر: Journal of Biological Chemistry. 293:579-587
مصطلحات موضوعية: 0301 basic medicine, Antigenicity, Zinc Transporter 8, Biochemistry, Antibodies, Mice, 03 medical and health sciences, Immune system, Antigen, Insulin-Secreting Cells, Extracellular, Animals, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Cytotoxicity, Molecular Biology, Mice, Knockout, biology, Chemistry, Rat Insulinoma, Molecular Bases of Disease, Cell Biology, Molecular biology, Rats, Transmembrane domain, Diabetes Mellitus, Type 1, 030104 developmental biology, Antigens, Surface, biology.protein, Antibody
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d80f08b4f9c6cc520ed48deeb9cf746Test
https://doi.org/10.1074/jbc.ra117.000195Test -
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المؤلفون: Guy A. Rutter, Dax Fu, Chengfeng Merriman, Qiong Huang
المصدر: Journal of Biological Chemistry. 291:26950-26957
مصطلحات موضوعية: 0301 basic medicine, Nonsynonymous substitution, medicine.medical_treatment, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Insulin, genetic polymorphism, Cation Transport Proteins, Phospholipids, diabetes, zinc, 11 Medical And Health Sciences, Cholesterol, Lysophosphatidylcholine, transporter, YIIP, 03 Chemical Sciences, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, membrane transporter reconstitution, medicine.medical_specialty, chemistry.chemical_element, Papers of the Week, Zinc Transporter 8, Zinc, Biology, drug discovery, 03 medical and health sciences, INSULIN SECRETORY GRANULES, Internal medicine, medicine, Humans, Allele, Molecular Biology, Science & Technology, MUTATIONS, HEK 293 cells, Lysophosphatidylcholines, Transporter, Cell Biology, 06 Biological Sciences, MICE, HEK293 Cells, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, chemistry, kinetics, Mutation, PANCREATIC BETA-CELLS, GLUCOSE-HOMEOSTASIS, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976976a6c18d90328c223c4655ad4f3fTest
https://doi.org/10.1074/jbc.m116.764605Test -
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المؤلفون: Israel Sekler, Yusaku Miyamae, Masaya Nagao, Eitan Hoch, Kazuhisa Fukue, Tokuji Tsuji, Dax Fu, Ayako Fukunaka, Taiho Kambe, Seiji Masuda, Taka-aki Takeda, Takashi Fujiwara, Chengfeng Merriman, Yukina Nishito, Shigeyuki Fujimoto
المصدر: Biochemical Journal. 473:2611-2621
مصطلحات موضوعية: 0301 basic medicine, Alanine, chemistry.chemical_classification, Mutant, Transporter, Cell Biology, Biology, Biochemistry, Article, Cell Line, 03 medical and health sciences, Enzyme activator, 030104 developmental biology, Enzyme, chemistry, Animals, Alkaline phosphatase, Amino Acid Sequence, Protein stabilization, Carrier Proteins, Chickens, Molecular Biology, Secretory pathway
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d7f2de1041fb43fbda1ec78032375aTest
https://doi.org/10.1042/bcj20160324Test