المؤلفون: Matthew R. Henn, Meghan Chafee, Bharat K. Misra, Liyang Diao, John G. Aunins, Brian G. Feagan, Jennifer R. Wortman, Amelia Tomlinson, Roger J. Pomerantz, Peng Zhao, Sherry Wang-Weigand, Michele Trucksis, Barbara H. McGovern, Christopher B. Ford, David N. Cook, William J. Sandborn, Patricia Bernardo, David I. Lichter, Curtis Huttenhower, Sheri L. Simmons, Edward J. O’Brien

المصدر: Gastroenterology

مصطلحات موضوعية: 0301 basic medicine, Male, Spores, LC-MS, Liquid chromatography-mass spectrometry, AhR, Aryl hydrocarbon receptor, Gastroenterology, Inflammatory bowel disease, DCA, Deoxycholic acid, 0302 clinical medicine, TMMS, Total modified Mayo score, 5-ASA, 5-aminosalicyclic acid, HMP2, Integrative Human Microbiome Project or iHMP, UDCA, Ursodeoxycholic acid, Middle Aged, Ulcerative colitis, Ursodeoxycholic acid, microbiome therapeutics, LCA, Lithocholic acid, Tolerability, Vancomycin, IBD, Inflammatory bowel disease, LC-MS/MS, Liquid chromatography-tandem mass spectrometry, 030211 gastroenterology & hepatology, Female, 2°BA, Secondary bile acid, medicine.drug, Adult, microbe-associated metabolites, medicine.medical_specialty, Firmicutes, BA, Bile acid, MGX, Metagenomic shotgun sequencing, Placebo, Article, 03 medical and health sciences, Double-Blind Method, MeDRA, Medical Dictionary for Regulatory Activities, Internal medicine, medicine, Humans, Dosing, Adverse effect, SCFA, Short-chain fatty acid, gastrointestinal microbiome, FMT, Fecal microbiota transplant, Hepatology, business.industry, TNF, Tumor necrosis factor, medicine.disease, UC, Ulcerative colitis, 030104 developmental biology, Colitis, Ulcerative, CFU, Colony forming unit, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17da58568b427b6d165f82d1d01a222dTest
http://europepmc.org/articles/PMC7402096Test

المؤلفون: Paul G. Richardson, Alessandra Di Bacco, Andrew Dorner, Allison Berger, Deborah Ricci, Pieter Sonneveld, Erik Koenig, Robert Z. Orlowski, Jeśus F.San Miguel, Hugues Bernard, Edward A. Stadtmauer, William L. Trepicchio, David I. Lichter, Helgi van de Velde, Sundar Jagannath, Matthew Schu, Kenneth C. Anderson, Stephen J. Blakemore, Nibedita Chattopadhyay, Dixie Lee Esseltine, George Mulligan, Joseph B. Bolen, Rachel Neuwirth, Bin Li, Sagar Lonial, James R. Berenson

المساهمون: Radiology & Nuclear Medicine, Epidemiology, Hematology

المصدر: Blood, 123(5), 632-639. American Society of Hematology

مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Clinical Trials and Observations, Immunology, Antineoplastic Agents, PDGFRA, Biology, Bioinformatics, medicine.disease_cause, Biochemistry, GTP Phosphohydrolases, Bortezomib, Cohort Studies, Proto-Oncogene Proteins p21(ras), immune system diseases, hemic and lymphatic diseases, Proto-Oncogene Proteins, medicine, Humans, neoplasms, Survival analysis, Multiple myeloma, Dexamethasone, Mutation, Dose-Response Relationship, Drug, Membrane Proteins, Cell Biology, Hematology, medicine.disease, Prognosis, Boronic Acids, Survival Analysis, digestive system diseases, Pyrazines, Cancer research, ras Proteins, KRAS, Multiple Myeloma, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc7a06d9996ee11f17c51fcbb70b586Test
https://europepmc.org/articles/PMC4123425Test/

المؤلفون: Joan Bladé, Dixie-Lee Esseltine, Melissa Alsina, Sagar Lonial, David I. Lichter, George Mulligan, Michael D. Sintchak, Pieter Sonneveld, Paul G. Richardson, Helgi van de Velde, William L. Trepicchio, Jamie Cavenagh, Olga Tayber, William S. Dalton, Kenneth C. Anderson, Ruben Niesvizky, Deborah Ricci, Hadi Danaee, Michael D. Pickard, Hongliang Shi, Thierry Facon

المساهمون: Hematology

المصدر: Blood, 120(23), 4513-4516. American Society of Hematology

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Genotype, Clinical Trials and Observations, Immunology, Single-nucleotide polymorphism, Antineoplastic Agents, Biology, Biochemistry, Polymorphism, Single Nucleotide, Dexamethasone, Bortezomib, Gene Frequency, Recurrence, hemic and lymphatic diseases, medicine, Humans, Gene, Multiple myeloma, Cell Biology, Hematology, Sequence Analysis, DNA, medicine.disease, Boronic Acids, Survival Analysis, PSMB5, Cysteine Endopeptidases, Protein Subunits, Treatment Outcome, Proteasome, Drug Resistance, Neoplasm, Pyrazines, Cancer research, Multiple Myeloma, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c77f9b625ea3bf0340ebadaccbfe43bTest
https://europepmc.org/articles/PMC3757460Test/

المؤلفون: Narsis Attar, Stephen Mok, Bartosz Chmielowski, Erika von Euw, Richard C. Koya, Charles Ng, Antoni Ribas, Deborah J.L. Wong, Barry L. Burgess, Tara A. McCannel, Sybil Zachariah, Mohammad Atefi, David I. Lichter, Elena S. Izmailova, Connie Chu

المصدر: Molecular Cancer
Molecular Cancer, Vol 11, Iss 1, p 22 (2012)
von Euw, Erika; Atefi, Mohammad; Attar, Narsis; Chu, Connie; Zachariah, Sybil; Burgess, Barry L; et al.(2012). Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines. Molecular Cancer, 11(1), 22. doi: http://dx.doi.org/10.1186/1476-4598-11-22Test. Retrieved from: http://www.escholarship.org/uc/item/7nz2c5npTest

مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Uveal Neoplasms, Cancer Research, Skin Neoplasms, MAP Kinase Signaling System, Pyridones, Antineoplastic Agents, Pyrimidinones, MAPK signaling, Biology, lcsh:RC254-282, Inhibitory Concentration 50, Phosphatidylinositol 3-Kinases, Cell Line, Tumor, medicine, Humans, Radioactive Tracers, Melanoma, Protein Kinase Inhibitors, MEK inhibitor, GNA11, Research, Cell Cycle, Wild type, Oncogenes, Cell cycle, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, BRAF mutation, Oncology, Drug Resistance, Neoplasm, Cutaneous melanoma, Cancer research, Molecular Medicine, Proto-Oncogene Proteins c-akt, GNAQ, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad85f0f62206a8da2c80d049f0a30867Test
https://pubmed.ncbi.nlm.nih.gov/22515704Test

المؤلفون: Erika Von Euw, Mohammad Atefi, Narsis Attar, Connie Chu, Sybil Zachariah, Barry L Burgess, Stephen Mok, Charles Ng, Deborah Jl Wong, Bartosz Chmielowski, David I Lichter, Richard C Koya, Tara A Mccannel, Elena Izmailova, Antoni Ribas

المساهمون: The Pennsylvania State University CiteSeerX Archives

مصطلحات موضوعية: Melanoma, MEK inhibitor, BRAF mutation, Oncogenes, MAPK signaling

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.409.4901Test

المؤلفون: Kenneth C. Anderson, William L. Trepicchio, Alessandra Di Bacco, Hugues Bernard, Pieter Sonneveld, Allison Berger, George Mulligan, Erik Koenig, Bin Li, Jesús F. San Miguel, Sagar Lonial, Paul G. Richardson, Dixie-Lee Esseltine, Stephen J. Blakemore, David I. Lichter, Matthew C. Schu

المصدر: Blood. 118:1377-1377

مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Oncology, medicine.medical_specialty, Mutation rate, business.industry, Bortezomib, Immunology, Cell Biology, Hematology, PDGFRA, medicine.disease, medicine.disease_cause, Biochemistry, Chromosome 17 (human), Leukemia, Internal medicine, Medicine, Cancer gene, KRAS, business, health care economics and organizations, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::913374ce9947540e2eb446db944f2ec1Test
https://doi.org/10.1182/blood.v118.21.1377.1377Test

المؤلفون: William L. Trepicchio, Hadi Danaee, Patrick J. LeRoy, George Mulligan, Jeffrey Ecsedy, David I. Lichter

المصدر: Molecular Cancer Therapeutics. 10:A41-A41

مصطلحات موضوعية: Serine/threonine-specific protein kinase, Cancer Research, Mitotic index, medicine.diagnostic_test, Aurora A kinase, Cancer, Biology, Cell cycle, medicine.disease, Molecular biology, chemistry.chemical_compound, Oncology, Western blot, chemistry, Alisertib, medicine, Immunohistochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9900da7660febc62438cf2104a02c662Test
https://doi.org/10.1158/1535-7163.targ-11-a41Test

المؤلفون: Tara A. McCannel, David I. Lichter, Mohammad Atefi, Sybil Zachariah, Antoni Ribas, Barry L. Burgess, Narsis Attar, Erika von Euw, Elena S. Izmailova

المصدر: Cancer Research. 71:3584-3584

مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Cancer Research, MEK Inhibitor TAK-733, medicine.diagnostic_test, GNA11, MEK inhibitor, Ocular Melanoma, Biology, Flow cytometry, Oncology, Cell culture, Immunology, medicine, Cancer research, GNAQ

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::10a9e0019041cac16b03cabfc8a5fa53Test
https://doi.org/10.1158/1538-7445.am2011-3584Test

المؤلفون: Russell M. Walker, William L. Trepicchio, David I. Lichter, Elena S. Izmailova

المصدر: Clinical Cancer Research. 16:A26-A26

مصطلحات موضوعية: Sanger sequencing, Cancer Research, Mutation, Melanoma, Mutant, Biology, medicine.disease_cause, medicine.disease, Molecular biology, symbols.namesake, Oncology, medicine, symbols, Allele, Gene, Genotyping, V600E

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::407916d760a75af0c221a6804cb43825Test
https://doi.org/10.1158/diag-10-a26Test

المؤلفون: Olga Tayber, Stephen J. Blakemore, Hadi Danaee, David I. Lichter, Hiroshi Miyake, Josephine Atienza, Michael D. Sintchak, Keiske Kuida

المصدر: Clinical Cancer Research. 16:B5-B5

مصطلحات موضوعية: Cancer Research, Exon, dbSNP, Oncology, Sequence analysis, HSP90AB1, biology.protein, Estrogen receptor, Single-nucleotide polymorphism, Biology, Molecular biology, Gene, Hsp90

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ed7154ce8100b1c2a4edb6ddf006272eTest
https://doi.org/10.1158/1078-0432.tcmusa10-b5Test