المؤلفون: Archana Vijayakumar, Ayse Okesli‐Armlovich, Ting Wang, Isabel Olson, Minji Seung, Saritha Kusam, David Hollenback, Sangeetha Mahadevan, Bruno Marchand, Maria Toteva, David G. Breckenridge, James L. Trevaskis, Jamie Bates

المصدر: Hepatology Communications, Vol 6, Iss 9, Pp 2298-2309 (2022)

مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2471-254XTest

الوصول الحر: https://doaj.org/article/fcccdbbbcc8c483fa465bc4bd08eb25cTest

المؤلفون: Ross Dobie, John R. Wilson-Kanamori, Beth E.P. Henderson, James R. Smith, Kylie P. Matchett, Jordan R. Portman, Karolina Wallenborg, Simone Picelli, Anna Zagorska, Swetha V. Pendem, Thomas E. Hudson, Minnie M. Wu, Grant R. Budas, David G. Breckenridge, Ewen M. Harrison, Damian J. Mole, Stephen J. Wigmore, Prakash Ramachandran, Chris P. Ponting, Sarah A. Teichmann, John C. Marioni, Neil C. Henderson

المصدر: Cell Reports, Vol 29, Iss 7, Pp 1832-1847.e8 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124719313245Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/3e037994cd354294a9745ce74fc85275Test

المؤلفون: Philipp Schwabl, Eva Hambruch, Grant R. Budas, Paul Supper, Michael Burnet, John T. Liles, Manfred Birkel, Ksenia Brusilovskaya, Philipp Königshofer, Markus Peck-Radosavljevic, William J. Watkins, Michael Trauner, David G. Breckenridge, Claus Kremoser, Thomas Reiberger

المصدر: Biomedicines, Vol 9, Iss 1, p 60 (2021)

مصطلحات موضوعية: NASH, FXR, cilofexor, portal hypertension, fibrosis, rats, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2227-9059/9/1/60Test; https://doaj.org/toc/2227-9059Test

الوصول الحر: https://doaj.org/article/2fd79bb2ed77480192c227cb6828b2edTest

المؤلفون: Shawn S. Badal, Tareq Al Tuhaifi, Ya-Fen Yu, David Lopez, Craig T. Plato, Kristin Joly, David G. Breckenridge, Hai-Chun Yang, John T. Liles, Agnes B. Fogo

المصدر: Kidney360

مصطلحات موضوعية: Male, Pyridines, Imidazoles, Angiotensin-Converting Enzyme Inhibitors, Standard of Care, General Medicine, Kidney, Rats, Rats, Sprague-Dawley, Editorial, Enalapril, Benzamides, Hypertension, Humans, Albuminuria, Animals, Diabetic Nephropathies, Renal Insufficiency, Chronic, Protein Kinase Inhibitors, Antihypertensive Agents, Original Investigation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db85c3bdd894d9b02c41556860b8ed07Test
https://pubmed.ncbi.nlm.nih.gov/35919531Test

المؤلفون: Swetha Pendem, Igor Mikaelian, Sarani Ghoshal, Anna Zagorska, Archana Vijayakumar, Katie Walker, Bryan C. Fuchs, Robert Brockett, K. Liu, Bruno Marchand, David Lopez, David G. Breckenridge, Li Li, Ricardo Ramirez, Jamie Bates, Saritha Kusam, Dmytro Kornyeyev, Saili Yi, David Newstrom, David Hollenback

المصدر: Journal of Hepatology. 73:896-905

مصطلحات موضوعية: Liver Cirrhosis, Male, 0301 basic medicine, Diet, High-Fat, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Fibrosis, Hepatic Stellate Cells, medicine, Animals, Humans, Rats, Wistar, Hepatology, Chemistry, Lipogenesis, Acetyl-CoA carboxylase, medicine.disease, Hepatic stellate cell activation, Rats, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Liver, Lipotoxicity, Hepatic stellate cell, Cancer research, 030211 gastroenterology & hepatology, Steatohepatitis, Hepatic fibrosis, Biomarkers, Acetyl-CoA Carboxylase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26e3434ea9bae5e5487db79bd3c5389Test
https://doi.org/10.1016/j.jhep.2020.04.037Test

المؤلفون: Gabriel A. Kwong, Jay Luther, Wendy Winckler, Kathleen E. Corey, Ann K. Daly, Olivier Govaere, Quentin M. Anstee, V. Ratziu, Andrew N. Billin, Dina Tiniakos, Sarah Sherman, Louis Gelrud, Anna Zagorska, David G. Breckenridge, Fayçal Touti, Eric K. Huang, John T. Liles, Nil Gural, Sangeeta N. Bhatia, Jamie Bates, Andrew Warren, Sophie C. Cazanave, Maciej Pacula, Raymond T. Chung, Grant R. Budas, Mehar Cheema, Sabrina Ibarra

المصدر: Science Translational Medicine. 13

مصطلحات موضوعية: Nonalcoholic steatohepatitis, medicine.medical_specialty, Drug trial, Extramural, business.industry, Urinary system, Patient screening, General Medicine, medicine.disease, Fibrosis, Gastroenterology, Non-alcoholic Fatty Liver Disease, Internal medicine, Nonalcoholic fatty liver disease, medicine, Humans, Peptides, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4725c996a3088773ce242d38a7b04cfTest
https://doi.org/10.1126/scitranslmed.abe8939Test

المؤلفون: Wanchi Fung, Kobayashi Tetsuya, Anita Niedziela-Majka, Bob Jiang, Kim Jordan, Saritha Kusam, David G. Breckenridge, Hai Yang, Britton Kenneth Corkey, Kristyna Elbel, Chin Tay, Elaine Kan, Sammy Metobo, David Sperandio, Du Jinfa, Richard M. Neve, Sophia L. Shevick, Eric B. Lansdon, Kerim Babaoglu, Gregory Chin, Heather Webb, Debi Jin, Annapurna Sapre, Vangelis Aktoudianakis, Latesh Lad, Jamie Bates, Xiaowu Chen, Jeff Zablocki, Gene Eisenberg, Nate Larson, Richard L. Mackman, Martinez Ruben, Magdeleine Hung, Zachary Newby, Mish Michael R

المصدر: Bioorganic & Medicinal Chemistry. 27:457-469

مصطلحات موضوعية: Benzimidazole, BRD4, Cell Survival, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Protein Domains, Cell Line, Tumor, Drug Discovery, Animals, Humans, Potency, Tumor growth, Epigenetics, Molecular Biology, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Aryl, Organic Chemistry, Isoxazoles, Neoplasms, Experimental, Bioavailability, Bromodomain, chemistry, Molecular Medicine, Benzimidazoles, Multiple Myeloma, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32393d33e86182931fa91168f5389d3cTest
https://doi.org/10.1016/j.bmc.2018.11.020Test

المؤلفون: Markus Peck-Radosavljevic, William J. Watkins, John T. Liles, Thomas Reiberger, Grant R. Budas, Ksenia Brusilovskaya, Eva Hambruch, Philipp Schwabl, Michael Burnet, Claus Kremoser, David G. Breckenridge, Philipp Königshofer, Manfred Birkel, Michael Trauner, P Supper

المصدر: Biomedicines
Volume 9
Issue 1
Biomedicines, Vol 9, Iss 60, p 60 (2021)

مصطلحات موضوعية: 0301 basic medicine, Mean arterial pressure, medicine.medical_specialty, Cirrhosis, Portal venous pressure, Medicine (miscellaneous), Propranolol, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, Internal medicine, NAFLD, cilofexor, Medicine, propranolol, lcsh:QH301-705.5, business.industry, cirrhosis, fibrosis, NASH, portal hypertension, medicine.disease, rats, 030104 developmental biology, Endocrinology, lcsh:Biology (General), FXR, Portal hypertension, 030211 gastroenterology & hepatology, Steatohepatitis, business, Hepatic fibrosis, farnesoid X receptor, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a092db3be3feda7def92ef951fb9c5eTest
https://pubmed.ncbi.nlm.nih.gov/33435509Test

المؤلفون: David G. Breckenridge, Laurie A. Castonguay, Giuseppe A. Papalia, Swetha Pendem, Shawn S. Badal, Ford Hinojosa-Kirschenbaum, Gregory T. Notte, Sarah Wise, Michael V. Lee, Keith A. Koch, Agnes B. Fogo, Dorothy French, Britton Kenneth Corkey, Frank Y. Ma, Brian E. Schultz, Eric B. Lansdon, Melanie H. Wong, David J. Nikolic-Paterson, Tareq M Al-Tuhaifi, Theodore Sullivan, Michael Graupe, Haichun Yang, Erik Huntzicker, Grant R. Budas, John T. Liles

المصدر: Journal of Clinical Investigation. 128:4485-4500

مصطلحات موضوعية: Male, 0301 basic medicine, Nephrology, medicine.medical_specialty, MAP Kinase Signaling System, Kidney Glomerulus, Renal function, MAP Kinase Kinase Kinase 5, Rats, Sprague-Dawley, Mice, Random Allocation, 03 medical and health sciences, Fibrosis, Internal medicine, medicine, Animals, Humans, Diabetic Nephropathies, ASK1, Protein Kinase Inhibitors, Mice, Knockout, Serine/threonine-specific protein kinase, Kidney, business.industry, Glomerulosclerosis, General Medicine, Fibroblasts, medicine.disease, Oxidative Stress, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Cancer research, Female, business, Research Article, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b037ace289b522c4f72e5fa892d048Test
https://doi.org/10.1172/jci99768Test

المؤلفون: John T. Liles, Frank Y. Ma, Liv Amos, David J. Nikolic-Paterson, Greg H. Tesch, David G. Breckenridge, Yingjie Han

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, Kidney Glomerulus, urologic and male genital diseases, Rats, Inbred WKY, p38 Mitogen-Activated Protein Kinases, Rats, Sprague-Dawley, Glomerulonephritis, Cell Movement, Fibrosis, Medicine, Rapidly progressive glomerulonephritis, ASK1, Phosphorylation, Kinase, 3. Good health, Proteinuria, Molecular Medicine, Female, Original Article, medicine.symptom, Signal Transduction, medicine.medical_specialty, p38 mitogen-activated protein kinases, Inflammation, macrophage, p38 MAPK, MAP Kinase Kinase Kinase 5, Nephrotoxicity, 03 medical and health sciences, Internal medicine, Renal fibrosis, Animals, Humans, Protein Kinase Inhibitors, thrombosis, business.industry, Macrophages, JNK Mitogen-Activated Protein Kinases, Original Articles, Cell Biology, Macrophage Activation, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Endocrinology, Gene Expression Regulation, inflammation, JNK, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339b4885367b1c644a0c188e5c9be022Test
https://doi.org/10.1111/jcmm.13705Test