Evaluation of environmental contamination by platinum and exposure risks for healthcare workers during a heated intraperitoneal perioperative chemotherapy (HIPEC) procedure

التفاصيل البيبلوغرافية
العنوان: Evaluation of environmental contamination by platinum and exposure risks for healthcare workers during a heated intraperitoneal perioperative chemotherapy (HIPEC) procedure
المؤلفون: Marc Pocard, Antoine Villa, Gabriel Fernandez, Joël Poupon, Robert Garnier, Danielle Mezzaroba, Helene Hasni-Pichard, Armande Konate
المصدر: Journal of Surgical Oncology. 103:6-9
بيانات النشر: Wiley, 2010.
سنة النشر: 2010
مصطلحات موضوعية: Operating Rooms, medicine.medical_specialty, Medical staff, Organoplatinum Compounds, Forceps, chemistry.chemical_element, Antineoplastic Agents, Air Pollutants, Occupational, Occupational Exposure, Perioperative chemotherapy, Medical Staff, Hospital, medicine, Humans, Gloves, Surgical, Infusions, Parenteral, Peritoneal Neoplasms, Platinum, Air filter, Inhalation exposure, Inhalation Exposure, business.industry, Carcinoma, Hyperthermia, Induced, General Medicine, Contamination, Combined Modality Therapy, Oxaliplatin, Surgery, Oncology, chemistry, Anesthesia, business, Environmental Monitoring, medicine.drug
الوصف: The study was plan to assess platinum (Pt) contamination in the operating room and its exposure to health workers during heated intraperitoneal perioperative chemotherapy (HIPEC) using oxaliplatin. Materials and Methods Pt was measured in urinary and environmental (air and surfaces) samples via inductively coupled plasma mass spectrometry (ICP-MS). Urinary samples were obtained from 11 members of the staff before and after the procedure and from 6 controls. Samples from 15 surfaces and from 3 filters from the air extractors were also analyzed for Pt contamination. Results Before HIPEC, Pt levels in urinary samples were similar in both the exposed and control groups; concentrations were below the limit of detection (i.e., 1.5 ng/L). No elevation was observed in the exposed group at the end of the procedure. Surgeon gloves were heavily contaminated. On other analyzed surfaces, lesser amounts of Pt were measured, ranging from 2 ng on the surgeon's hands to 183 ng on the forceps. All three air filters tested negative. Conclusion No contamination of healthcare workers or of the air in the operating room was detected. However, the heavy contamination of the surgeon's gloves demonstrates why doubling of specialized gloves for the surgeon should be mandatory. J. Surg. Oncol. 2011;103:6–9. © 2010 Wiley-Liss, Inc.
تدمد: 0022-4790
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7aab71b61a9fca3fd26e26e17164c0dTest
https://doi.org/10.1002/jso.21740Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....c7aab71b61a9fca3fd26e26e17164c0d
قاعدة البيانات: OpenAIRE