يعرض 1 - 10 نتائج من 47 نتيجة بحث عن '"Daniel Andrade da Cunha"', وقت الاستعلام: 1.46s تنقيح النتائج
  1. 1
    دورية أكاديمية
    RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate

    المؤلفون: Thasso Griebel, Jean-Valery Turatsinze, Olatz Villate, Laurence Ladrière, Decio L. Eizirik, Marco Bugliani, Lorella Marselli, Daniel Andrade Da Cunha, Michael Sammeth, Mariana Igoillo-Esteve, Piero Marchetti, Baroj Abdulkarim, Izortze Santin, Mark I. McCarthy, Matilde Masini, Guy Bottu, Miriam Cnop

    مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, Internal Medicine

    العلاقة: url:https://www.openaccessrepository.it/communities/itmirrorTest; https://www.openaccessrepository.it/record/117575Test

    الإتاحة: https://doi.org/10.2337/db13-1383Test
    https://www.openaccessrepository.it/record/117575Test

    View record in BASE

    أضف إلى المفضلة
  2. 2
    Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity

    المؤلفون: Miriam Cnop, Mariana Igoillo-Esteve, Maria Lytrivi, Miguel Lopes, Victoria Rosengren, Kassem Ghaddar, Daniel Andrade Da Cunha, Henrik Ortsäter, Decio L. Eizirik, Janne Lehtiö, Piero Marchetti, Henrik J. Johansson, Anthony Piron, Xiaoyan Yi, Lorella Marselli

    المصدر: BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
    BMC Genomics
    BMC genomics, 21 (1

    مصطلحات موضوعية: Proteomics, 0106 biological sciences, Beta-cells, Proteome, lcsh:QH426-470, lcsh:Biotechnology, Pancreatic islets, Palmitates, RNA-sequencing, Apoptosis, FOXO1, Biology, Free fatty acids, 01 natural sciences, Transcriptome, 03 medical and health sciences, Endoplasmic reticulum stress, Lipid metabolism, Type 2 diabetes, Downregulation and upregulation, Insulin-Secreting Cells, lcsh:TP248.13-248.65, Genetics, Humans, Liver X receptor, Protein kinase A, Transcription factor, 030304 developmental biology, 0303 health sciences, Sciences bio-médicales et agricoles, Cell biology, lcsh:Genetics, Diabetes Mellitus, Type 2, Lipotoxicity, Unfolded protein response, Research Article, 010606 plant biology & botany, Biotechnology

    وصف الملف: 1 full-text file(s): application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be488677bb3f79d2aa26646786cd7c67Test
    https://doi.org/10.1186/s12864-020-07003-0Test


    أضف إلى المفضلة
  3. 3
    Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis

    المؤلفون: Miriam Cnop, Laurence Ladrière, Lorella Marselli, Mariana Igoillo-Esteve, Piero Marchetti, Daniel Andrade Da Cunha, Miriam H Hernangomez, Baroj Abdulkarim

    المصدر: Endocrinology
    Endocrinology, 158 (6

    مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Programmed cell death, Cells, Biologie générale, Wistar, Drug Resistance, Apoptosis, Biology, 03 medical and health sciences, Endocrinology, Insulin-Secreting Cells, Internal medicine, medicine, Animals, Humans, Rats, Wistar, Protein kinase A, Antihypertensive Agents, Cells, Cultured, Diabétologie, Cultured, Guanabenz, Kinase, Endoplasmic reticulum, Biologie moléculaire, Enseignement des sciences, Endoplasmic Reticulum Stress, Lipids, Rats, 3. Good health, 030104 developmental biology, Lipotoxicity, Unfolded protein response, Phosphorylation, Biologie cellulaire, Biologie, medicine.drug

    وصف الملف: 1 full-text file(s): application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70379928518ffcfe414dde2779cb6aa1Test
    https://doi.org/10.1210/en.2016-1773Test


    أضف إلى المفضلة
  4. 4
    In vitro use of free fatty acids bound to albumin: A comparison of protocols

    المؤلفون: Mariana Igoillo-Esteve, Daniel Andrade Da Cunha, Piero Marchetti, Ana F Oliveira, Miriam Cnop, Marco Bugliani, Laurence Ladrière

    المصدر: BioTechniques, 58 (5

    مصطلحات موضوعية: Genetics and Molecular Biology (all), Biologie générale, Palmitates, Fatty Acids, Nonesterified, Biochemistry, General Biochemistry, Genetics and Molecular Biology, Albumins, Animals, Humans, Diabétologie, Chemistry, Fatty Acids, Albumin, Biologie moléculaire, Enseignement des sciences, Sciences bio-médicales et agricoles, In vitro, Nonesterified, Biologie cellulaire, Cattle, Oleic Acid, Protein Binding, Biochemistry, Genetics and Molecular Biology (all), Biotechnology, Biologie

    وصف الملف: 1 full-text file(s): application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c4ab6da70d584bf7f42e0eab6e8ca9Test
    https://doi.org/10.2144/000114285Test


    أضف إلى المفضلة
  5. 5
    Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)

    المؤلفون: Decio L. Eizirik, Andrii Domanskyi, Maria Lindahl, Monia Cito, Marco Bugliani, Piero Marchetti, Cristina Cosentino, Tatiana Danilova, Fabio Arturo Grieco, Daniel Andrade Da Cunha, Miriam Cnop, Laurence Ladrière

    المصدر: Journal of Biological Chemistry
    The Journal of biological chemistry, 292 (36

    مصطلحات موضوعية: 0301 basic medicine, type 1 diabetes, Biologie générale, mitochondrial apoptosis, thrombospondin, Endoplasmic Reticulum, Biochemistry, Thrombospondin 1, chemistry.chemical_compound, Mice, Insulin-Secreting Cells, cytokine, Cells, Cultured, Cultured, islet, IL-1, endoplasmic reticulum stress (ER stress), inflammation, interferon, β-cell, Animals, Cytokines, Humans, Inflammation, Nerve Growth Factors, Oxidative Stress, Thapsigargin, Molecular Biology, Cell Biology, Cytoprotection, 3. Good health, Cell biology, Biologie, Intracellular, medicine.medical_specialty, Programmed cell death, Cells, Biology, 03 medical and health sciences, Internal medicine, medicine, Diabétologie, Thrombospondin, Endoplasmic reticulum, Biologie moléculaire, Enseignement des sciences, 030104 developmental biology, Endocrinology, chemistry, Unfolded protein response, Biologie cellulaire

    وصف الملف: 2 full-text file(s): application/pdf; application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afebd1181aba57371d16059b42c42d6Test
    https://europepmc.org/articles/PMC5592674Test/


    أضف إلى المفضلة
  6. 6
    JunB protects β-cells from lipotoxicity via the XBP1–AKT pathway

    المؤلفون: Decio L. Eizirik, Daniel Andrade Da Cunha, Marco Bugliani, Fernanda Ortis, Esteban Nicolas Gurzov, Alessandra K Cardozo, Najib Naamane, Miriam Cnop, Piero Marchetti

    المصدر: Cell Death & Differentiation. 21:1313-1324

    مصطلحات موضوعية: Male, X-Box Binding Protein 1, XBP1, JUNB, Regulatory Factor X Transcription Factors, Biology, Insulin-Secreting Cells, hemic and lymphatic diseases, Animals, Humans, Phosphorylation, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Original Paper, Cell Biology, Middle Aged, Rats, DNA-Binding Proteins, Diabetes Mellitus, Type 2, Lipotoxicity, Cancer research, Unfolded protein response, Female, Signal transduction, Proto-Oncogene Proteins c-akt, Signal Transduction, Transcription Factors

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae79efa33e4729ddd35589237b4d08f0Test
    https://doi.org/10.1038/cdd.2014.53Test


    أضف إلى المفضلة
  7. 7
    Phenylpropenoic acid glucoside from rooibos protects pancreatic beta cells against cell death induced by acute injury

    المؤلفون: Piero Marchetti, Miriam Cnop, Daniel Andrade Da Cunha, Marco Bugliani, Eddy Himpe, Imane Song, Luc Bouwens

    المساهمون: Basic (bio-) Medical Sciences, Cell Differentiation

    المصدر: PloS one, 11 (6
    PLoS ONE
    PLoS ONE, Vol 11, Iss 6, p e0157604 (2016)

    مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, Genetics and Molecular Biology (all), Phytochemistry, Necrosis, Phytochemicals, Psychologie appliquée, lcsh:Medicine, Apoptosis, Plant Science, Pharmacology, medicine.disease_cause, Biochemistry, Endocrinology, Glucosides, Insulin-Secreting Cells, Medicine and Health Sciences, Cytotoxic T cell, lcsh:Science, Cells, Cultured, Aged, 80 and over, Staining, Mice, Inbred BALB C, Multidisciplinary, Cell Death, Phenylpropionates, Aspalathus, Organic Compounds, Plant Biochemistry, Medicine (all), Monosaccharides, Cell Staining, Middle Aged, Sciences bio-médicales et agricoles, Nucleic acids, Chemistry, Cell Processes, Physical Sciences, medicine.symptom, Beta cell, Biologie, medicine.drug, Research Article, Programmed cell death, Endocrine Disorders, Carbohydrates, Biology, Protective Agents, Research and Analysis Methods, Diabetes Mellitus, Experimental, Necrotic Cell Death, 03 medical and health sciences, medicine, Diabetes Mellitus, Genetics, Animals, Humans, Agricultural and Biological Sciences (all), Biochemistry, Genetics and Molecular Biology (all), Aged, Cell Proliferation, Cell growth, Plant Extracts, lcsh:R, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, Cell Biology, DNA, Streptozotocin, Oxidative Stress, 030104 developmental biology, Glucose, Specimen Preparation and Treatment, Metabolic Disorders, DNA damage, lcsh:Q, Oxidative stress

    وصف الملف: 1 full-text file(s): application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe17e90cbca4a667247e00c4e39f1b4Test
    http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/236893Test


    أضف إلى المفضلة
  8. 8
    Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway

    المؤلفون: Miriam Cnop, Daniel Andrade Da Cunha, Jean-Marie Vanderwinden, Jeffery D. Molkentin, Per-Ola Carlsson, Monia Cito, Decio L. Eizirik, Marco Bugliani, Piero Marchetti

    مصطلحات موضوعية: Male, 0301 basic medicine, Programmed cell death, Cell Survival, NF-E2-Related Factor 2, Palmitic Acid, Biology, Endoplasmic Reticulum, medicine.disease_cause, Models, Biological, Antioxidants, Thrombospondin 1, Mice, eIF-2 Kinase, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Insulin-Secreting Cells, Puma, medicine, Animals, Humans, Rats, Wistar, Molecular Biology, Original Paper, Cell Biology, Endoplasmic reticulum, Neurodegeneration, JNK Mitogen-Activated Protein Kinases, Middle Aged, Endoplasmic Reticulum Stress, medicine.disease, biology.organism_classification, Lipids, Cell biology, Oxidative Stress, 030104 developmental biology, Lipotoxicity, Cytoprotection, 030220 oncology & carcinogenesis, Proteolysis, Female, Apoptosis Regulatory Proteins, Oxidative stress, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e8b45dfe8839effa417ba8652e211fTest
    http://hdl.handle.net/11568/831792Test


    أضف إلى المفضلة
  9. 9
    DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

    المؤلفون: Ute Volkmar, Silvia Del Guerra, Daniel Andrade Da Cunha, Rachel Deplus, Decio L. Eizirik, Miriam Cnop, Emilie Calonne, Sarah Dedeurwaerder, Marco Bugliani, Michael Volkmar, Mariana Igoillo-Esteve, Piero Marchetti, Matilde Masini, Matladi N. Ndlovu, Najib Naamane, Matthieu Defrance, François Fuks

    المصدر: The EMBO Journal. 31:1405-1426

    مصطلحات موضوعية: Genetics, endocrine system, 0303 health sciences, endocrine system diseases, General Immunology and Microbiology, General Neuroscience, Pancreatic islets, 030209 endocrinology & metabolism, Promoter, Methylation, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, CpG site, DNA methylation, medicine, Genetic predisposition, Epigenetics, Molecular Biology, 030304 developmental biology, Epigenetics of diabetes Type 2

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9e24644c0187452824a686e325f31318Test
    https://doi.org/10.1038/emboj.2011.503Test


    أضف إلى المفضلة
  10. 10
    A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly

    المؤلفون: Andrew T. Hattersley, Anne Philippi, Mathilde Daures, Cécile Julier, Céline Derbois, Mariana Igoillo-Esteve, Valérie Senée, Decio L. Eizirik, Heather P. Harding, Miriam Cnop, Baroj Abdulkarim, Daniel Andrade Da Cunha, Marc Nicolino, Sophie Romero, Nathalie Bendelac, Miguel Lopes, David Ron

    المساهمون: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Harding, Heather [0000-0002-7359-7974], Ron, David [0000-0002-3014-5636], Apollo - University of Cambridge Repository, Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA)

    المصدر: Diabetes
    Diabetes, American Diabetes Association, 2015, 64 (11), pp.3951-62. ⟨10.2337/db15-0477⟩
    Europe PubMed Central

    مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Microcephaly, Protein Phosphatase 1/*genetics, Adolescent, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], Phosphatase, Mutation, Missense, Biology, environment and public health, Dephosphorylation, Internal medicine, Protein Phosphatase 1, Internal Medicine, medicine, Diabetes Mellitus, Missense mutation, Humans, EIF2AK3, Diabetes Mellitus/*genetics, Growth Disorders/*genetics, Growth Disorders, Genetics, Microcephaly/*genetics, Genetics/Genomes/Proteomics/Metabolomics, Protein phosphatase 1, Syndrome, Mutation, medicine.disease, 3. Good health, enzymes and coenzymes (carbohydrates), Endocrinology, Mutation (genetic algorithm), Phosphorylation, Female, biological phenomena, cell phenomena, and immunity, Missense

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea67a5465bc32d9a1fcef631f2f8ff4Test
    https://hal.archives-ouvertes.fr/hal-01850506Test


    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS — أرسل هذا البحث بالبريد الإلكتروني — حفظ البحث